Post List

  • January 18, 2017
  • 04:30 AM
  • 12 views

Alterations in Leg Stiffness Following A Concussion May Lead to Changes in Return-to-Play Protocol

by Jane McDevitt in Sports Medicine Research (SMR): In the Lab & In the Field

An athlete with a recent concussion has altered lower extremity stiffness at the leg, hip, and knee, which could increase their risk for musculoskeletal injury.... Read more »

Dubose DF, Herman DC, Jones DL, Tillman SM, Clugston JR, Pass A, Hernandez JA, Vasilopoulos T, Horodyski M, & Chmielewski TL. (2017) Lower Extremity Stiffness Changes after Concussion in Collegiate Football Players. Medicine and science in sports and exercise, 49(1), 167-172. PMID: 27501359  

  • January 18, 2017
  • 03:13 AM
  • 13 views

Physical activity levels and autism (again)

by Paul Whiteley in Questioning Answers

"Adolescents with ASD [autism spectrum disorder] spent less time in MVPA [moderate and vigorous physical activity] compared to TD [typically developing] adolescents (29 min/day vs. 50 min/day, p < 0.001) and fewer met the Physical Activity Guidelines for Americans (14 vs. 29%, p > 0.05)."So said the study results published by Heidi Stanish and colleagues [1] adding yet more to another growth autism research area - physical activity and exercise - ........ Read more »

  • January 17, 2017
  • 05:05 PM
  • 25 views

Axl and GAS6: apoptotic mimicry and NLRP-3 inhibition during Zika Virus infection

by thelonevirologist in Virology Tidbits

Zika Virus (ZIKV) is a positive sense RNA virus that belongs to the Flavivirus genus of the Flaviviridae family that includes other human pathogens including Hepatitis C Virus (HCV), Yellow Fever Virus (YFV), West Nile Virus, Dengue Virus (DENV), Tick Borne Encephalitis Virus (TBEV), and Japanese Encephalitis Virus (JEV).
Although being first isolated in 1947, until recently ZIKV was not associated with severe disease; following the introduction of ZIKV in the Americas however, foetal ZIKV inf........ Read more »

Retallack H, Di Lullo E, Arias C, Knopp KA, Laurie MT, Sandoval-Espinosa C, Mancia Leon WR, Krencik R, Ullian EM, Spatazza J.... (2016) Zika virus cell tropism in the developing human brain and inhibition by azithromycin. Proceedings of the National Academy of Sciences of the United States of America, 113(50), 14408-14413. PMID: 27911847  

El Costa H, Gouilly J, Mansuy JM, Chen Q, Levy C, Cartron G, Veas F, Al-Daccak R, Izopet J, & Jabrane-Ferrat N. (2016) ZIKA virus reveals broad tissue and cell tropism during the first trimester of pregnancy. Scientific reports, 35296. PMID: 27759009  

Quicke KM, Bowen JR, Johnson EL, McDonald CE, Ma H, O'Neal JT, Rajakumar A, Wrammert J, Rimawi BH, Pulendran B.... (2016) Zika Virus Infects Human Placental Macrophages. Cell host , 20(1), 83-90. PMID: 27247001  

Savidis, G., Perreira, J., Portmann, J., Meraner, P., Guo, Z., Green, S., & Brass, A. (2016) The IFITMs Inhibit Zika Virus Replication. Cell Reports, 15(11), 2323-2330. DOI: 10.1016/j.celrep.2016.05.074  

Brass AL, Huang IC, Benita Y, John SP, Krishnan MN, Feeley EM, Ryan BJ, Weyer JL, van der Weyden L, Fikrig E.... (2009) The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus. Cell, 139(7), 1243-54. PMID: 20064371  

Bailey CC, Zhong G, Huang IC, & Farzan M. (2014) IFITM-Family Proteins: The Cell's First Line of Antiviral Defense. Annual review of virology, 261-283. PMID: 25599080  

Meertens L, Carnec X, Lecoin MP, Ramdasi R, Guivel-Benhassine F, Lew E, Lemke G, Schwartz O, & Amara A. (2012) The TIM and TAM families of phosphatidylserine receptors mediate dengue virus entry. Cell host , 12(4), 544-57. PMID: 23084921  

Bhattacharyya S, Zagórska A, Lew ED, Shrestha B, Rothlin CV, Naughton J, Diamond MS, Lemke G, & Young JA. (2013) Enveloped viruses disable innate immune responses in dendritic cells by direct activation of TAM receptors. Cell host , 14(2), 136-47. PMID: 23954153  

  • January 17, 2017
  • 07:03 AM
  • 32 views

Simultaneous near-Sun observations of a moving type IV radio burst and the associated white-light CME by K. Hariharan et al.*

by CESRA in Solar Radio Science

Quasi-continuum radio emissions of duration ~10-60 min that occur along with flares and coronal mass ejections (CMEs) in the solar atmosphere are termed as type IV bursts. The bursts are non-thermal in nature and can be classified into two categories, i.e. moving type IV (type IVm) bursts and stationary type [...]... Read more »

  • January 17, 2017
  • 04:28 AM
  • 38 views

Vitamin D supplementation and self-perceived fatigue

by Paul Whiteley in Questioning Answers

"Vitamin D treatment significantly improved fatigue in otherwise healthy persons with vitamin D deficiency."Supplementation details, described in the paper by Albina Nowak and colleagues [1] (open-access available here), were a single dose of 100,000 IU [international units] of vitamin D or a placebo (mannitol) administered to 120 adult participants who presented with "fatigue and vitamin D deficiency (serum 25(OH)D < 20 μg/L)." This was a double-blind trial and self-perceived fatigue ........ Read more »

Nowak A, Boesch L, Andres E, Battegay E, Hornemann T, Schmid C, Bischoff-Ferrari HA, Suter PM, & Krayenbuehl PA. (2016) Effect of vitamin D3 on self-perceived fatigue: A double-blind randomized placebo-controlled trial. Medicine, 95(52). PMID: 28033244  

  • January 16, 2017
  • 04:29 PM
  • 36 views

Op, Op, Op. The Neuroscience of Gangnam Style?

by Neuroskeptic in Neuroskeptic_Discover

"Our results revealed characteristic patterns of brain activity associated with Gangnam Style". So say the authors of a new paper called Neural correlates of the popular music phenomenon.



The authors, Qiaozhen Chen et al. from Zhejiang in China, used fMRI to record brain activity while 15 volunteers listened to two musical pieces: Psy's 'Gangnam Style' and a "light music" control, Richard Clayderman's piano piece 'A Comme Amour'.

Chen et al. say that Gangnam Style was associated with "... Read more »

Chen Q, Zhang Y, Hou H, Du F, Wu S, Chen L, Shen Y, Chao F, Chung JK, Zhang H.... (2017) Neural correlates of the popular music phenomenon: evidence from functional MRI and PET imaging. European journal of nuclear medicine and molecular imaging. PMID: 28083689  

  • January 16, 2017
  • 12:50 PM
  • 45 views

Five things to consider when designing a policy to measure research impact [Originally published in The Conversation]

by SciELO in SciELO in Perspective

The move of the Australian government to measure the impact of university research on society introduces many new challenges that were not previously relevant when evaluation focused solely on academic merit. … Read More →... Read more »

  • January 16, 2017
  • 09:52 AM
  • 36 views

Simple Jury Persuasion: Using your expert  witnesses’ hands help persuade jurors

by Rita Handrich in The Jury Room

You may have seen our blog post where we talk about research that informs us in patent work to either allow jurors to examine a disputed invention up close or to simply have them view it from a distance. Which strategy we recommend you use all depends on the evidence and your specific case. Today, […]... Read more »

Vallée-Tourangeau F, Steffensen SV, Vallée-Tourangeau G, & Sirota M. (2016) Insight with hands and things. Acta Psychologica, 195-205. PMID: 27569687  

  • January 16, 2017
  • 03:11 AM
  • 52 views

Autism-like traits and/or autism elevated in psychosis

by Paul Whiteley in Questioning Answers

"Rates of ASD [autism spectrum disorder] and ASD traits are elevated in a psychosis population."The paper by Debbie Kincaid and colleagues [1] provides yet more [short] blogging material pertinent to the increasing interest in how psychosis may be yet another comorbidity over-represented when it comes to autism (see here) and vice-versa. I know this is another topic that has to be treated with some caution in terms of concepts like stigma but more discussions - science discussions........ Read more »

  • January 15, 2017
  • 07:04 AM
  • 79 views

What Differential-K Theory gets Wrong about Race Differences in Sexuality

by Scott McGreal in Eye on Psych

This post critiques a study that attempted to test predictions of differential-K theory about racial differences in sexuality using data from a Durex condom survey. Better, more scientific data addresses this topic, and fails to confirm the predictions of this theory.... Read more »

Dutton, E., van der Linden, D., & Lynn, R. (2016) Population differences in androgen levels: A test of the Differential K theory. Personality and Individual Differences, 289-295. info:/

  • January 15, 2017
  • 06:05 AM
  • 64 views

Population Differences in Androgens Fail to Validate Richard Lynn's Claims about Racial Differences in Penis Size

by Scott McGreal in Eye on Psych

The author of a study on population differences in androgens claimed that his findings support Lynn's claims about racial differences in penis length. Close analysis of the statistics used shows these conclusions are invalid.... Read more »

Dutton, E., van der Linden, D., & Lynn, R. (2016) Population differences in androgen levels: A test of the Differential K theory. Personality and Individual Differences, 289-295. info:/

  • January 15, 2017
  • 05:45 AM
  • 69 views

“World’s toughest bacterium” - Deinococcus radiodurans

by Usman Paracha in SayPeople

The bacterium, Deinococcus radiodurans, is thought to be discovered as a contaminant in radiation-sterilized cans in 1960s. The name of the bacterium comes from the Ancient Greek, i.e. deinos and kokkos meaning “terrible grain/berry”, and the Latin language, i.e. radius and durare, meaning “radiation surviving”. The bacterium is also known as Conan the Bacterium.

Deinococcus radiodurans is a comparatively larger bacterium having spherical shape. It is a red-pigmented b........ Read more »

  • January 15, 2017
  • 03:47 AM
  • 76 views

Neuroscience Can't Heal a Divided Nation

by The Neurocritic in The Neurocritic




Brain activation during challenges to political vs. non-political beliefs (Figure modified from Kaplan et al., 2016).


Lately I've been despairing about the state of America.




I'm not sure how denying access to affordable health care, opposing scientific facts like global warming and the benefits of vaccines, alienating our allies, banning Muslims, building a wall, endorsing torture, and

... Read more »

  • January 14, 2017
  • 11:53 AM
  • 87 views

What Can fMRI Tell Us About Mental Illness?

by Neuroskeptic in Neuroskeptic_Discover

A remarkable and troubling new paper: Addressing reverse inference in psychiatric neuroimaging: Meta-analyses of task-related brain activation in common mental disorders



Icahn School of Medicine researchers Emma Sprooten and colleagues carried out an ambitious task: to pull together the results of every fMRI study which has compared task-related brain activation in people with a mental illness and healthy controls.

Sprooten et al.'s analysis included 537 studies with a total of 21,427 ... Read more »

  • January 14, 2017
  • 04:35 AM
  • 173 views

No significant difference in circulating cytokines in autism vs controls?

by Paul Whiteley in Questioning Answers

"As compared with 54 typically developing controls, we found no evidence of differences in the blood profile of immune mediators supportive of active systemic inflammation mechanisms in participants with autism."That was the unexpected research bottom-line published by Carlos Pardo and colleagues [1] (open-access) examining whether various immune-related chemicals - "cytokines, chemokines, or growth factors in serum and cerebrospinal fluid" - might be linked to autism following longitudinal........ Read more »

  • January 13, 2017
  • 07:02 AM
  • 33 views

Internet commenters, crying men, psychiatrists on trial, and good  bosses

by Doug Keene in The Jury Room

It is still so early in 2017 and yet, it is time for another installation of tidbits, miscellany, odds and ends, and accumulated wisdom with which you can amaze your friends and impress family members. And that we don’t want to just toss disrespectfully into recycling when it could bring so much joy to your […]... Read more »

  • January 13, 2017
  • 05:11 AM
  • 92 views

Nutrient-dependent FNIP degradation regulates FLCN localization and promotes renal cancer progression

by Joana Guedes in BHD Research Blog

Birt-Hogg-Dubé (BHD) syndrome is a rare disorder caused by mutations in FLCN and associated with increased risk of kidney cancer. It has been shown that FLCN-interacting protein 1 and 2 (FNIP1 and FNIP2) double knockout mice, like the FLCN knockout mice, develop renal carcinoma (Hasumi et al., 2015). However, the molecular mechanisms linking FNIP and FLCN remain unknown. In their new study, Nagashima et al. (2016) show that FNIP2 undergoes proteasome-dependent degradation via β-TRCP ........ Read more »

  • January 13, 2017
  • 05:00 AM
  • 82 views

Friday Fellow: Branching Vase Sponge

by Piter Boll in Earthling Nature

by Piter Kehoma Boll A fascinating group of animals that has not yet joined the Friday Fellows are the sponges. Different from all other animals, sponges have a unique body structure that behaves more like a plant or fungus. They … Continue reading →... Read more »

  • January 13, 2017
  • 03:13 AM
  • 98 views

Exercise as an intervention for anxiety?

by Paul Whiteley in Questioning Answers

"Our data suggest that exercise is more effective than control at reducing anxiety symptoms."So said the meta-analysis published by Brendan Stubbs and colleagues [1] who surveyed the peer-reviewed literature "investigating the benefits of exercise compared to usual treatment or control conditions in people with an anxiety and/or stress-related disorders." From the 6 randomised, controlled trials found "from inception until December 2015" exercise (various types of exercise regime) did seem to ha........ Read more »

  • January 13, 2017
  • 02:40 AM
  • 84 views

Acute coronary syndrome on Friday the 13th: a case for re-organising services?

by Rogue Medic in Rogue Medic

"However, patients admitted on five day/number combinations were 20-30% more likely to survive at 13 years. These findings could be explained by subgroup analysis inflation of the type I error, although supernatural causes merit further investigation.[1]"

No. Supernatural causes do not merit further investigation, at least, not based on anything in this paper.

The authors used Friday the 13th as their "normal" date for comparison with every other date, but the outcomes ........ Read more »

Protty, M., Jaafar, M., Hannoodee, S., & Freeman, P. (2016) Acute coronary syndrome on Friday the 13th: a case for re-organising services?. The Medical Journal of Australia, 205(11), 523-525. DOI: 10.5694/mja16.00870  

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