Post List

  • April 8, 2017
  • 09:53 AM
  • 281 views

Publication Alert: High Nucleotide Resolution Study of the Skin Virome

by Geoffrey Hannigan in Prophage

A few weeks ago some colleagues and myself published a new manuscript looking at the diversity of the human skin virome. In our previous previous work, we evaluated the diversity of viruses on the skin. Other groups have looked at virus diversity at other body sites including the gut, lungs...... Read more »

  • April 8, 2017
  • 04:13 AM
  • 321 views

One more time folks... pregnancy folate and autism risk

by Paul Whiteley in Questioning Answers

Folate yet again on this blog? Sorry but that's just how the peer-reviewed papers have fallen..."Maternal folate supplementation during pregnancy may reduce the risk of ASD [autism spectrum disorder] in the offspring, especially in the Western population."So said the meta-analysis by Yu and colleagues [1] reporting on a topic that has seen quite a lot of research interest down the years (see here). Authors this time around cumulatively examined data for some 4,500 cases of autism compared w........ Read more »

  • April 7, 2017
  • 03:02 PM
  • 40 views

Outsourcing and precariousness of work in the social assistance policy

by SciELO in SciELO in Perspective | Press Releases

This paper presents the work conditions of psychologists hired by private organizations to work at the Sistema Único de Assistência Social (Unified System for Social Assistance). Among other things, it concludes that this “outsourcing” process has been allowing temporary contracts, high turnover rates, late payment of salaries, dismissal of large groups of employees and lack of continuing education, which impacts the health of the workers and the quality of the services offered. … Re........ Read more »

  • April 7, 2017
  • 02:18 PM
  • 291 views

Are we in the GSM Radar?

by SciELO in SciELO in Perspective

Google Scholar Metrics (GSM) offers alternative metrics to the JCR Impact Factor and the SJR, namely the h-5 index. To enter this world ranking that covers more than 40,000 journals it is only necessary to publish an average of 20 articles per year and be cited. However, there are hundreds of journals (our journals) that are not being indexed in GSM. They're off Radar. … Read More →... Read more »

Enrique Ordua-Malea, Alberto Martín-Martín, Juan M. Ayllón, & Emilio Delgado López Cozar. (2016) La revolución Google Scholar: destapando la caja de Pandora académica. Universidad de Granada. info:/

  • April 7, 2017
  • 07:02 AM
  • 63 views

Which science is most “certain” according to the American public? 

by Rita Handrich in The Jury Room

When litigation cases rely on science or highly technical information, it is critical to help jurors understand the information underlying the case at a level that makes sense to them. If they do not understand your “science”, they will simply guess which party to vote for or “follow the crowd”. Here’s an example of what […]... Read more »

Broomell, S., & Kane, P. (2017) Public perception and communication of scientific uncertainty. Journal of Experimental Psychology: General, 146(2), 286-304. DOI: 10.1037/xge0000260  

  • April 7, 2017
  • 07:00 AM
  • 72 views

Friday Fellow: Amphibian chytrid fungus

by Piter Boll in Earthling Nature

by Piter Kehoma Boll Today I’m bringing you a species that is probably one of the most terrible ones to exist today, the amphibian chytrid fungus, Batrachochytrium dendrobatidis, also known simply as Bd. The amphibian chytrid fungus, as its name says, is … Continue reading →... Read more »

  • April 7, 2017
  • 06:22 AM
  • 256 views

Novel FLCN mutations in Chinese patients

by Joana Guedes in BHD Research Blog

The gene FLCN is inactivated in individuals with BHD syndrome. The FLCN gene encodes the protein Folliculin, which is a putative tumour suppressor. Over 150 different FLCN mutations have been identified, most of which are likely to be pathogenic (LOVD-hosted FLCN mutation database). The majority of these mutations are frameshift, nonsense, insertion/deletion, or splice site mutations, resulting in truncation and inactivation of the encoded protein folliculin. FLCN consists of 14 exons spanning a........ Read more »

  • April 7, 2017
  • 04:48 AM
  • 317 views

Folate-dependent one carbon metabolism and transsulfuration pathways: biomarkers for autism?

by Paul Whiteley in Questioning Answers

I found it a little unusual that the findings reported by Daniel Howsmon and colleagues [1] (open-access) talking about "multivariate statistical analysis presented herein [provided] unprecedented quantitative classification results for separating participants into ASD [autism spectrum disorder] and NEU [neurotypical] cohorts based solely on biochemical data" merited a rapid reply in a prominent science magazine pouring cold water on the results (see here). Not least bec........ Read more »

  • April 6, 2017
  • 02:44 AM
  • 320 views

"a single intravenous infusion of autologous umbilical cord blood" and autism

by Paul Whiteley in Questioning Answers

'Could stem cells offer hope for autism?' went one media headline referencing the very preliminary "phase I, open-label trial" published by Geraldine Dawson and colleagues [1] (open-access) detailing the experiences of a single intravenous infusion of autologous umbilical cord blood in 25 children with "a confirmed diagnosis of ASD [autism spectrum disorder]."Well, the results were promising in respect of important issues such as safety in light of the tenet 'first do no harm': "Assess........ Read more »

Geraldine Dawson, Jessica M. Sun, Katherine S. Davlantis, Michael Murias,, Lauren Franz, Jesse Troy, Ryan Simmons, Maura Sabatos-DeVito, Rebecca Durham, & Joanne Kurtzberg. (2017) Autologous Cord Blood Infusions Are Safe and Feasible in Young Children with Autism Spectrum Disorder: Results of a Single-Center Phase I Open-Label Trial. Stem Cells Translational Medicine. info:/10.1002/sctm.16-0474

  • April 5, 2017
  • 07:02 AM
  • 275 views

Your Black client is much more likely to be wrongfully convicted

by Doug Keene in The Jury Room

Those of us who’ve been around for a while have heard this repeatedly. But, lest you think times are changing, here’s some sobering data from a March, 2017 report co-edited by a Michigan State University College of Law Professor. From the beginning, this is a disturbing report. Here’s how it starts: African-Americans are only 13% […]... Read more »

Samuel R. Gross, Maurice Possley, & Klara Stephens. (2017) Race and Wrongful Convictions in the United States. . UC Irvine: National Registry of Exonerations. . info:/

  • April 5, 2017
  • 04:30 AM
  • 268 views

Elbow Stress May Compromise Elbow Health

by Catherine E. Lewis in Sports Medicine Research (SMR): In the Lab & In the Field

Workers and athletes exposed to greater elbow stress (from vibration, high forces, or high repetition) may be more likely to develop elbow osteoarthritis. ... Read more »

  • April 5, 2017
  • 03:14 AM
  • 316 views

Paediatric congenital heart disease and autism risk (again)

by Paul Whiteley in Questioning Answers

"Risk of autism spectrum disorder screening status in children with congenital heart defects was higher than expected from population rates."So said the findings reported by Jessica Bean Jaworski and colleagues [1] who set about "to assess the rates of autism spectrum disorders in a large sample of children with a history of congenital heart defects and to assess medical, behavioral, and individual factors that may be associated with the risk of autism spectrum disorders." Covering a topic that ........ Read more »

Bean Jaworski JL, Flynn T, Burnham N, Chittams JL, Sammarco T, Gerdes M, Bernbaum JC, Clancy RR, Solot CB, Zackai EH.... (2017) Rates of autism and potential risk factors in children with congenital heart defects. Congenital heart disease. PMID: 28299880  

  • April 4, 2017
  • 06:00 PM
  • 183 views

New rice fights off drought

by adam phillips in It Ain't Magic

Researchers have created drought resistant transgenic rice using a gene from a small Eurasian flowering plant.... Read more »

  • April 4, 2017
  • 11:00 AM
  • 297 views

Researchers Finally Ask: Does Your Cat Even Like To Be Around You?

by Miss Behavior in The Scorpion and the Frog

This cat has had enough and is running away from home. Photo by Danielle Menuey.While dogs happily and obliviously boast the reputation of being “man’s best friend”, cats have a reputation of being antisocial, independent, and downright grumpy. But do cats really deserve that? Scientists finally decided to find out.Kristin Vitale Shreve and Monique Udell from Oregon State University and Lindsay Mehrkam from Monmouth University asked 25 pet cats and 25 shelter cats their preferences. H........ Read more »

  • April 4, 2017
  • 02:55 AM
  • 274 views

Autism, ageing and comorbidity

by Paul Whiteley in Questioning Answers

I'm not spending too much time today on the findings published by Elizabeth Wise and colleagues [1] but did want to bring them to your attention. Looking at the presentation of "comorbidities and behavioral and neuropsychiatric symptoms" in relation to autism in the context of ageing, some important details were noted. Not least that "GI [gastrointestinal] disorders (68.9%) and seizure disorders (23%) were common, and 25.7% of the sample had a BMI [body mass index] >30" wh........ Read more »

  • April 4, 2017
  • 12:49 AM
  • 233 views

A clue towards understanding intrinsically disordered proteins

by ragothamanyennamalli in Getting to know Structural Bioinformatics

ntrinsically disordered proteins are thought to be fully functional, yet do not confirm to a single conformation, thereby identifying their structure via crystallography becomes problematic. Many intrinsically disordered proteins have been studied and analyzed using NMR methods, however the question as to why proteins are intrinsically disordered is still debatable.... Read more »

  • April 3, 2017
  • 01:00 PM
  • 52 views

Medical practice precariousness at the Unified Health System — SUS

by SciELO in SciELO in Perspective | Press Releases

The medical practice in the Unified Health System is a study topic published in the journal Estudos de Psicologia (Campinas), which reveals the working conditions of these professionals and the impacts on personal health, analyzed through interviews and self-confidence. … Read More →... Read more »

  • April 3, 2017
  • 10:59 AM
  • 270 views

Criminal defense? Brain scans could show whether “they did it  on purpose”

by Rita Handrich in The Jury Room

When my kids were younger, I used to talk to them about the difference between intent and impact as they struggled to understand the varying reactions of people to their behavior. Back in 2009, we posted on some new research showing that we reacted more indignantly when bad deeds were done “on purpose”. Here is […]... Read more »

Vilares I, Wesley MJ, Ahn WY, Bonnie RJ, Hoffman M, Jones OD, Morse SJ, Yaffe G, Lohrenz T, & Montague PR. (2017) Predicting the knowledge-recklessness distinction in the human brain. Proceedings of the National Academy of Sciences of the United States of America, 114(12), 3222-3227. PMID: 28289225  

  • April 3, 2017
  • 10:23 AM
  • 272 views

Financial Scam Vulnerability: Brain Risk Factors

by William Yates, M.D. in Brain Posts

It is always frustrating when you hear about a financial scam that has target a vulnerable population like the elderly population.Elderly individuals may be targeted for a variety of reasons. First, they often have financial resources. Second, they may be a generally more trustworthy group increasing risk for falling for a scam. Third, elderly may suffer from some age-related brain changes that impair cognition and judgment.A recent research study suggests specific brain deficits may increase vu........ Read more »

  • April 3, 2017
  • 09:00 AM
  • 253 views

"Science is Under Attack." A Climate Scientist's Call to Action for the Future of our Planet.

by EE Giorgi in CHIMERAS

It’s a foggy morning in London. Meteorologist George Simpson, the director of the British Meteorological Office, sips his tea and opens a paper authored by a scientist named Guy Stewart Callendar. The last sentence of the abstract reads, “The temperature observations at 200 meteorological stations are used to show that world temperatures have actually increased at an average rate of 0.005°C per year during the past half century.”Simpson shakes his head and thinks, “Nonsense. It’s all ........ Read more »

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