The role of the immune system in Alzheimer’s disease is a hot topic, but exactly how the two are connected and what interventions could help lower risk remain a mystery. In a new study, researchers in the Ann Romney Center for Neurologic Diseases at Brigham and Women’s Hospital (BWH) investigate how genetic risk factors for Alzheimer’s disease may influence a key type of immune cell. Their results lay the groundwork for designing better therapeutic strategies and better prediction tools fo........ Read more »
Chan, G., White, C., Winn, P., Cimpean, M., Replogle, J., Glick, L., Cuerdon, N., Ryan, K., Johnson, K., Schneider, J.... (2015) CD33 modulates TREM2: convergence of Alzheimer loci. Nature Neuroscience. DOI: 10.1038/nn.4126
MedicalResearch.com Interview with: Dr. Wilfried Gwinner Div. of Nephrology and Hypertension University of Hanover Medical School Hannover and Dr. Uta Erdbruegger Div. Nephrology and Hypertension Division University of Virginia, Charlottesville Medical Research: What is the background for this study? … Continue reading →
The post Study Does Not Support Significant Role of CMV Virus In Transplant Outcomes appeared first on MedicalResearch.com.
... Read more »
Dr. Wilfried Gwinner and Dr. Uta Erdbruegger. (2015) Study Does Not Support Significant Role of CMV Virus In Transplant Outcomes. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Dr. Rebecca Prince MBBS Clinical Research Fellow and first author and Monika K. Krzyzanowska, MD MPH FRCPC Medical Oncologist, Princess Margaret Cancer Centre, Associate Professor, Dept of Medicine and Institute of Health Policy, Management & Evaluation, University of … Continue reading →
The post Many Patients Require Hospitalization During Chemotherapy appeared first on MedicalResearch.com.
... Read more »
Dr. Rebecca Prince MBBS. (2015) Many Patients Require Hospitalization During Chemotherapy. MedicalResearch.com. info:/
MedicalResearch.com Interview with: M.A. Frouws, Study Coordinator ASPIRIN trial MD PhD Candidate Datacenter Heelkunde, K6-R Leiden University Medical Center Leiden, the Netherlands Medical Research: What is the background for this study? What are the main findings? Response: The effect of … Continue reading →
The post Aspirin Prolongs Survival In All GI Cancers Except Pancreatic appeared first on MedicalResearch.com.
... Read more »
M.A. Frouws, Study Coordinator ASPIRIN trial. (2015) Aspirin Prolongs Survival In All GI Cancers Except Pancreatic. MedicalResearch.com. info:/
Does this sight make you want to yawn? A yawning Japanese macaque by Daisuke Tashiro at Wikimedia Commons.Do you think it would make other animals want to yawn? Many animals yawn spontaneously, but yawning in response to sensing or thinking about someone else doing it may be a completely different thing. Contagious yawning requires a sense of social connection and emotional empathy that not all species share. So far, scientists have found experimental evidence of contagious yawning in humans, ch........ Read more »
Gallup, A., Swartwood, L., Militello, J., & Sackett, S. (2015) Experimental evidence of contagious yawning in budgerigars (Melopsittacus undulatus). Animal Cognition, 18(5), 1051-1058. DOI: 10.1007/s10071-015-0873-1
An analysis of the OPTN/UNOS database from 1999-2011 reveals that 63.6% of all living kidney donors were either overweight* or obese. (emphasis mine): “Overweight and mildly obese kidney donors have increased through time by 12% and 20% every 5 years, respectively “ Obesity is associated with numerous health risks, including Type 2 Diabetes and …
Continue reading »
The post 63.6% of Living Kidney Donors Are Overweight appeared first on Living Donors Are People Too......... Read more »
Sachdeva, M. (2015) Weight trends in United States living kidney donors: Analysis of the UNOS database. World Journal of Transplantation, 5(3), 137. DOI: 10.5500/wjt.v5.i3.137
There are many things we read and discard rather than sharing them (and our take on them) with you, but other things we read and grin and think you might want to know. We’ve described these before as odd facts for sharing over drinks or dinner or around the office. It isn’t the most pivotal […]
“Cultural competency” is important for your financial bottom line
The Donald Trump Effect: Press coverage can determine public opinion and maybe election outcomes
Things ........ Read more »
Caputo, G. (2015) Dissociation and hallucinations in dyads engaged through interpersonal gazing. Psychiatry Research, 228(3), 659-663. DOI: 10.1016/j.psychres.2015.04.050
An ancient mass grave, uncovered during the construction of a shopping mall outside San Francisco, contains the bodies of seven men who appear to have been victims of “mass homicide” some 1,150 years ago, scientists say.
... Read more »
Eerkens JW, Carlson T, Malhi RS, Blake J, Bartelink EJ, Barfod GH, Estes A, Garibay R, Glessner J, Greenwald AM.... (2015) Isotopic and genetic analyses of a mass grave in central California: Implications for precontact hunter-gatherer warfare. American journal of physical anthropology. PMID: 26331533
The solitary inventor, buried away in garage or shed, is the classic depiction of introvert as born problem-solver. But new research, published recently in Psychological Studies, suggests that it’s extraverted people who perform better at classical tests of problem-solving, thanks to their tendency to be motivated in ways that are helpful for achieving.Vidya Athota at the University of Notre Dame, Australia and Richard Roberts at the Center for Innovative Assessments in New York ran compu........ Read more »
"ASD [autism spectrum disorder] might be overlooked in older adults and especially within geriatric psychiatry when diagnosing and treating depression and anxiety in older patients one should be attentive to ASD."So concluded Hilde Geurts and colleagues  as a function of their results looking for the presence of autistic traits in older adults with and without depressive disorders participating in the Netherlands study of depression in older persons (NESDO) initiative. Based on........ Read more »
Geurts, H., Stek, M., & Comijs, H. (2015) Autism characteristics in older adults with depressive disorders. The American Journal of Geriatric Psychiatry. DOI: 10.1016/j.jagp.2015.08.003
Take Home Message: Single and repetitive mild traumatic brain injury (mTBI) accelerates tauopathy among mice genetically predisposed to tau build up.... Read more »
Xu L, Ryu J, Nguyen JV, Arena J, Rha E, Vranis P, Hitt D, Marsh-Armstrong N, & Koliatsos VE. (2015) Evidence for accelerated tauopathy in the retina of transgenic P301S tau mice exposed to repetitive mild traumatic brain injury. Experimental Neurology, 168-176. PMID: 26311071
This post is the first in a series sparked by the selection of books for the History of Cataloguing section of the reading list for the core cataloguing module on the MA LIS. It highlights what Ranganathan had to say in his Five Laws (1931) regarding Cataloguing.... Read more »
S.R. Ranganathan. (1931) The Five Laws of Library Science. Hathi Trust Digital Library. info:/
A woman who won’t drive long distances because she has panic attacks in the car. A man who has contamination fears so intense he cannot bring himself to use public bathrooms. A woman who can’t go to church because she fears enclosed spaces. All of these people have two things in common: they have an anxiety disorder. They’re also parents.... Read more »
Ginsburg, G., Drake, K., Tein, J., Teetsel, R., & Riddle, M. (2015) Preventing Onset of Anxiety Disorders in Offspring of Anxious Parents: A Randomized Controlled Trial of a Family-Based Intervention. American Journal of Psychiatry. DOI: 10.1176/appi.ajp.2015.14091178
MedicalResearch.com Interview with: Talley Holman, PhD, MBA Senior eHealth Systems Analyst, Practice Advancement American Academy of Family Physicians Leawood, KS 66211 and John Beasley MD Professor of Family Medicine School of Medicine and Public Health and the Department of Industrial … Continue reading →
The post Electronic Health Records Not Adaptive To Patient-Centered Primary Care appeared first on MedicalResearch.com.
... Read more »
Talley Holman, PhD, MBA and John Beasley MD. (2015) Electronic Health Records Not Adaptive To Patient-Centered Primary Care. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Anthony V. D’Amico, MD, PhD Chief, Division of Genitourinary Radiation Oncology Professor of Radiation Oncology, Harvard Medical School Medical Research: What is the background for this study? What are the main findings? Dr. D’Amico: Controversy exists as … Continue reading →
The post Androgen Deprivation Therapy For Prostate Cancer May Not Be Prudent In Men With Heart Attack History appeared first on MedicalResearch.com.
... Read more »
Anthony V. D'Amico, MD, PhD. (2015) Androgen Deprivation Therapy For Prostate Cancer May Not Be Prudent In Men With Heart Attack History. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Susanna C. Larsson PhD, Associate Professor Associate professor, Nutritional Epidemiology Institute of Environmental Medicine Karolinska Institutet Stockholm, Sweden Medical Research: What are the main findings? Dr. Larsson: A high dietary cholesterol intake has been postulated to increase the … Continue reading →
The post Eggs Not Linked To Heart Attack or Stroke appeared first on MedicalResearch.com.
... Read more »
Susanna C. Larsson. (2015) Eggs Not Linked To Heart Attack or Stroke. MedicalResearch.com. info:/
Scene from Listening, a new neuro science fiction film by writer-director Khalil Sullins. What are some of the goals of research in human neuroscience?To explain how the mind works.To unravel the mysteries of consciousness and free will.To develop better treatments for mental and neurological illnesses.To allow paralyzed individuals to walk again.Brain decoding experiments that use fMRI or ECoG (direct recordings of the brain in epilepsy patients) to deduce what a person is looking at or sa........ Read more »
Stocco, A., Prat, C., Losey, D., Cronin, J., Wu, J., Abernethy, J., & Rao, R. (2015) Playing 20 Questions with the Mind: Collaborative Problem Solving by Humans Using a Brain-to-Brain Interface. PLOS ONE, 10(9). DOI: 10.1371/journal.pone.0137303
A remarkable paper just published in PLoS ONE reports on what is, I think, one of the largest psychological experiments of all time.
Researchers Elizabeth L. Paluck and colleagues partnered with a TV network to insert certain themes (or messages) into popular dramas shown on US TV. They then looked to see whether these themes had an effect on real world behavior, ranging from Google searches to drink-driving arrests.
The study was based on three prime time Spanish-language dramas (tele... Read more »
Paluck EL, Lagunes P, Green DP, Vavreck L, Peer L, & Gomila R. (2015) Does Product Placement Change Television Viewers' Social Behavior?. PloS one, 10(9). PMID: 26398217
A team including the scientist who first harnessed the revolutionary CRISPR-Cas9 system for mammalian genome editing has now identified a different CRISPR system with the potential for even simpler and more precise genome engineering. In the study researchers describe the unexpected biological features of this new system and demonstrate that it can be engineered to edit the genomes of human cells.... Read more »
Zetsche, B., Gootenberg, J., Abudayyeh, O., Slaymaker, I., Makarova, K., Essletzbichler, P., Volz, S., Joung, J., van der Oost, J., Regev, A.... (2015) Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System. Cell. DOI: 10.1016/j.cell.2015.09.038
I was interested to read the paper by Joseph Prandota and colleagues  who observed that: "latent chronic T. gondii [Toxoplasma gondii] infection have an important impact on triggering and development of ASD [autism spectrum disorders], at least in a subset of autistic children, and this requires some modification(s) of its diagnostic procedures and treatment regimens." Big words, I'm sure you'll agree.From the start I'll indicate that I'm interested in T. gondii on this bl........ Read more »
Joseph Prandota, Noha Abdel Fattah Elleboudy, Khadiga Ahmed Ismail, Osama Kamal Zaki, & Hanan Hussein Shehata. (2015) Increased Seroprevalence of Chronic Toxoplasmosis in Autistic Children: Special Reference to the Pathophysiology of IFN-γ and NO Overproduction. International Journal of Neurology Research, 1(3), 102-122. info:/10.17554/j.issn.2313-5611.2015.01.30
Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.
If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.
Research Blogging is powered by SMG Technology.
To learn more, visit seedmediagroup.com.