by Piter Kehoma Boll Recently the appearance of a new pokémon, Cutiefly, has brought a lot of attention to the real world species in which it is based. So why not bring it to Friday Fellow so that you may … Continue reading →... Read more »
Brooks, A. (2012) Identification of Bombyliid Parasites and Hyperparasites of Phalaenidae of the Prairie Provinces of Canada, with Descriptions of Six Other Bombyliid Pupae (Diptera). The Canadian Entomologist, 84(12), 357-373. DOI: 10.4039/Ent84357-12
Jazykov (Zakhvatkin), A. (2009) Parasites and Hyperparasites of the Egg-pods of injurious Locusts (Acridodea) of Turkestan. Bulletin of Entomological Research, 22(03), 385. DOI: 10.1017/S0007485300029904
Science headlines eh? Who would trust them and their sometimes inflated press releases?I start today with a science headline taken from the BBC website reading: "Pregnancy multivitamins 'are a waste of money'" based on the findings of a review article  published in the journal Drug and Therapeutics Bulletin.In it we are told that complex multi-vitamin and mineral supplements are 'unlikely to be needed and are an unnecessary expense' during the nine months that made us. Further that certain vi........ Read more »
Medication roulette, if you have ever had to deal with depression or other types of mental illness you know what I'm talking about. You take a pill that could help or could cause all sorts of horrid side effects. You cross your fingers as you take that first pill and in the 4-6 weeks it takes to start working you cross your fingers, hope, wish and probably even dread the outcome. But why does it take so long for antidepressants to start working in the first place and what could be done to c........ Read more »
Erb, S., Schappi, J., & Rasenick, M. (2016) Antidepressants Accumulate in Lipid Rafts Independent of Monoamine Transporters to Modulate Redistribution of the G protein, Gα . Journal of Biological Chemistry. DOI: 10.1074/jbc.M116.727263
Deep space missions could increase the chances of cardiovascular diseases, thereby increasing the chances of deaths in astronauts.
NASA’s Apollo program sent 9 manned missions and 24 astronauts above the low Earth orbit (LEO) during decades of 1960s and 1970s. Those missions also included Apollo 11, which was used to take Neil Armstrong and Buzz Aldrin to the moon. However, it appears that such beyond Earth missions........ Read more »
Delp, M., Charvat, J., Limoli, C., Globus, R., & Ghosh, P. (2016) Apollo Lunar Astronauts Show Higher Cardiovascular Disease Mortality: Possible Deep Space Radiation Effects on the Vascular Endothelium. Scientific Reports, 29901. DOI: 10.1038/srep29901
Gron gazed across the plain from inside a tuft of long grass. There. Just in front of the far hillock. Gazelles. Meals on legs. He vaguely remembered mother carrying him through cooler forests when he was not yet old enough to walk. He had never understood why they had left. But he had learned, had […]... Read more »
Zeder MA. (2008) Domestication and early agriculture in the Mediterranean Basin: Origins, diffusion, and impact. Proceedings of the National Academy of Sciences of the United States of America, 105(33), 11597-604. PMID: 18697943
Lazaridis, I., Nadel, D., Rollefson, G., Merrett, D., Rohland, N., Mallick, S., Fernandes, D., Novak, M., Gamarra, B., Sirak, K.... (2016) Genomic insights into the origin of farming in the ancient Near East. Nature. DOI: 10.1038/nature19310
The paper by Traolach Brugha and colleagues  makes for some blogging fodder today and the suggestion that: "The combined prevalence of autism in adults of all ages in England was 11/1000."Just before going through the Brugha paper it is perhaps appropriate to put it into some context based on other work from this group previously covered on this blog (see here) and the findings again by Brugha and colleagues  (a further report on their findings that time around can be seen h........ Read more »
Brugha TS, Spiers N, Bankart J, Cooper SA, McManus S, Scott FJ, Smith J, & Tyrer F. (2016) Epidemiology of autism in adults across age groups and ability levels. The British journal of psychiatry : the journal of mental science. PMID: 27388569
A team of Toronto scientists has found similarities in brain impairments in children with autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD) and obsessive compulsive disorder (OCD). The study involved brain imaging of white matter in 200 children with autism, ADHD, OCD or no diagnosis.
... Read more »
Ameis, S., Lerch, J., Taylor, M., Lee, W., Viviano, J., Pipitone, J., Nazeri, A., Croarkin, P., Voineskos, A., Lai, M.... (2016) A Diffusion Tensor Imaging Study in Children With ADHD, Autism Spectrum Disorder, OCD, and Matched Controls: Distinct and Non-Distinct White Matter Disruption and Dimensional Brain-Behavior Relationships. American Journal of Psychiatry. DOI: 10.1176/appi.ajp.2016.15111435
The e-book Global report shows that the traditional model based on large publishing houses was insufficient to incorporate the possibilities of technological advances. On the one hand, the new reading models through smartphones and subscription platforms and on the other hand, self-publishing of ebooks open opportunities to both individual authors and non-profit organizations in the educational field to produce and distribute their own works at low cost and minimal infrastructure requirements. &........ Read more »
WISCHENBART, R.,, & et al. (2016) Global eBook: a report on market trends an developments. Rüdiger Wischenbart Content and Consulting (RWCC). info:/
If you're ever lost in a remote European forest, you might be able to get your bearings by finding a herd of roe deer. These animals like to align themselves roughly north-south, whether they're standing still or fleeing danger.
Roe deer are small, reddish or grayish grazers common in Europe and Asia. Petr Obleser, of the Czech University of Life Sciences in Prague, and his coauthors studied the behavior of these skittish herbivores to look for evidence that they can sense the earth's ma........ Read more »
One would think that people with few friends and living in poverty are more at risk for PTSD than those with a strong support network and many resources. And that's true.
However, it is a different story when you look at the country-, rather than the individual level. Countries with more resources, such as the USA and the Netherlands, have higher levels of PTSD than countries with fewer resources (e.g. Colombia, South Africa).
... Read more »
Dückers ML, Alisic E, & Brewin CR. (2016) A vulnerability paradox in the cross-national prevalence of post-traumatic stress disorder. The British Journal of Psychiatry. PMID: 27445357
Food puzzles will help satisfy your cat’s hunting instinct, but most cats are missing out.A new paper on food puzzle toys for cats has plenty of ideas to get everyone started on these wonderful enrichment items. The research, led by Mikel Delgado (University of California, Berkeley; Feline Minds), combines a review of the scientific literature on food toys as feline enrichment with practical tips gained from the authors’ work as feline behaviour practitioners.Food puzzles are toys that make ........ Read more »
Dantas, L., Delgado, M., Johnson, I., & Buffington, C. (2016) Food puzzles for cats: feeding for physical and emotional wellbeing. Journal of Feline Medicine and Surgery. DOI: 10.1177/1098612X16643753
In a new paper that could prove explosive, Australian neuropathologists C. V. Dennis and colleagues report that they found very little evidence for adult neurogenesis in humans.
In recent years, the idea that neurogenesis - the production of new neurons - occurs in specific regions of the adult brain has become widely accepted, and much discussed. Disruptions to neurogenesis have been proposed to play a role in stress, depression, and other disorders.
However, Dennis et al. say that ne... Read more »
Dennis CV, Suh LS, Rodriguez ML, Kril JJ, & Sutherland GT. (2016) Human adult neurogenesis across the ages: An immunohistochemical study. Neuropathology and applied neurobiology. PMID: 27424496
Human papillomaviruses (HPV) are a diverse group of small double-stranded DNA viruses with specific mucosal or cutaneous tropisms. It is estimated that up to 80% of sexually active individuals will become infected with HPV sometime in their lifetime, making HPV the most prevalent sexually transmitted infection. HPVs can be further divided into high- and low-risk genotypes, based on their oncogenic potential. High-risk HPVs are implicated as causal in nearly 100% of cervical cancers, approximatel........ Read more »
Cicchini L, Westrich JA, Xu T, Vermeer DW, Berger JN, Clambey ET, Lee D, Song JI, Lambert PF, Greer RO.... (2016) Suppression of Antitumor Immune Responses by Human Papillomavirus through Epigenetic Downregulation of CXCL14. mBio, 7(3). PMID: 27143385
Stransky N, Egloff AM, Tward AD, Kostic AD, Cibulskis K, Sivachenko A, Kryukov GV, Lawrence MS, Sougnez C, McKenna A.... (2011) The mutational landscape of head and neck squamous cell carcinoma. Science (New York, N.Y.), 333(6046), 1157-60. PMID: 21798893
Anayannis NV, Schlecht NF, & Belbin TJ. (2015) Epigenetic Mechanisms of Human Papillomavirus-Associated Head and Neck Cancer. Archives of pathology , 139(11), 1373-8. PMID: 25978766
Cancer Genome Atlas Network. (2015) Comprehensive genomic characterization of head and neck squamous cell carcinomas. Nature, 517(7536), 576-82. PMID: 25631445
Burgers WA, Blanchon L, Pradhan S, de Launoit Y, Kouzarides T, & Fuks F. (2007) Viral oncoproteins target the DNA methyltransferases. Oncogene, 26(11), 1650-5. PMID: 16983344
Schlecht NF, Kulaga S, Robitaille J, Ferreira S, Santos M, Miyamura RA, Duarte-Franco E, Rohan TE, Ferenczy A, Villa LL.... (2001) Persistent human papillomavirus infection as a predictor of cervical intraepithelial neoplasia. JAMA, 286(24), 3106-14. PMID: 11754676
One the tenets of science is that hypotheses can't be proved, only disproved. But medical journals do not publish negative data, even though this is often helpful to scientists and physicians. A recent TED Talk by Ben Goldacre illustrates this point in the context of drug studies. In a bigger sense – is this really the only way to do science; to follow this one scientific method?... Read more »
Ben Goldacre. (2012) What doctors don't know about the drugs they prescribe. TED MED. info:/
Patients who sustained an anterior cruciate ligament (ACL) rupture were more likely to develop secondary meniscal injury and arthritis when compared to a matched cohort. Specifically, those that were treated nonoperatively or with delayed surgery may be more likely to develop secondary meniscal injury, develop arthritis, and be in need of a total knee replacement when compared with those patients treated with early surgery.... Read more »
Sanders, T., Kremers, H., Bryan, A., Fruth, K., Larson, D., Pareek, A., Levy, B., Stuart, M., Dahm, D., & Krych, A. (2016) Is Anterior Cruciate Ligament Reconstruction Effective in Preventing Secondary Meniscal Tears and Osteoarthritis?. The American Journal of Sports Medicine, 44(7), 1699-1707. DOI: 10.1177/0363546516634325
"The meta-analysis provided evidence for higher blood glutamate levels in ASD [autism spectrum disorder]."That was the research bottom-line reported by Zhen Zheng and colleagues  (open-access available here) who surveyed the current peer-reviewed science literature in this area and found something to see based on: "Twelve studies involving 880 participants and 446 incident cases."Drawing on the idea that glutamate is a rather important amino acid that plays a role in various biological p........ Read more »
Zheng Z, Zhu T, Qu Y, & Mu D. (2016) Blood Glutamate Levels in Autism Spectrum Disorder: A Systematic Review and Meta-Analysis. PloS one, 11(7). PMID: 27390857
Everyone does it ...no, not poop, but fart. Passing gas, fuming, crop dusting, cracking a rat -- no matter what you call it -- everyone fart, but why? Researchers have published an article devoted to the review of gaseous neurotransmitters of microbial origin and their role in the human body.
... Read more »
Oleskin, A., & Shenderov, B. (2016) Neuromodulatory effects and targets of the SCFAs and gasotransmitters produced by the human symbiotic microbiota. Microbial Ecology in Health . DOI: 10.3402/mehd.v27.30971
Morels and several other fungi (all members of the order Pezizales) are known to produce their mushrooms in recently burned soil, whether it's the result of a nice little campfire or an entire forest going up in smoke. The fire creates the right conditions for the fungus, which lies beneath the ground and so protected from flames and heat, to send up mushrooms. These mushrooms release spores into the environment, and the circle of life continues ever onward.In the case of morels, it's thought a ........ Read more »
Greene D, Hesketh M, & Pounden E. (2009) Emergence of morel (Morchella) and pixie cup (Geopyxis carbonaria) ascocarps in response to the intensity of forest floor combustion during a wildfire. . Mycologia, 102(4), 766-773. DOI: 10.3852/08-096
I going to assume that readers have some background knowledge about probiotics, gut bacteria, bacterial dysbiosis and coeliac disease before reading this post. I'd love to be able to give detailed descriptions of each here but fear that this would turn a short post into a much longer one...So... in a previous post titled: 'Probiotics degrading gluten peptides?' I covered the potentially important suggestion that certain types of bacteria might have the ability to breakdown (degrade) immunog........ Read more »
Caminero, A., Galipeau, H., McCarville, J., Johnston, C., Bernier, S., Russell, A., Jury, J., Herran, A., Casqueiro, J., Tye-Din, J.... (2016) Duodenal bacteria from patients with celiac disease and healthy subjects distinctly affect gluten breakdown and immunogenicity. Gastroenterology. DOI: 10.1053/j.gastro.2016.06.041
Male Ilyoplax pusilla crabs wave their claws in the air to attract females, but why do different-sized males spend different amounts of time waving? The answer lies in research published this year. ... Read more »
Kawano, Y., & Henmi, Y. (2016) Female preference for large waving claws in the dotillid crab Ilyoplax pusilla. Journal of Ethology. DOI: 10.1007/s10164-016-0471-y
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