E. fishelsoni s a bacterium that breaks the rules. It grows from 10 µm long to a fully visible 0.7 mm….in twelve hours! Normally, diffusion isn’t adequate for a bacterium this big because it takes too long for two interacting proteins to find one another. But what if the bacterium make more of the protein, so much more that it can find a partner all the time. How can you make that much of each protein? E. fishelsoni does it by making 85,000 copies of its genome….. ever........ Read more »
Bresler V, Montgomery WL, Fishelson L, Pollak PE. (1998) Gigantism in a bacterium, Epulopiscium fishelsoni, correlates with complex patterns in arrangement, quantity, and segregation of DNA. J Bacteriol., 180(21), 5061-5611. info:/9791108
MedicalResearch.com Interview with: Dr. Giuseppe Andò University of Messina, Messina, Italy Medical Research: What is the background for this study? Dr. Andò: Patients’ preference for radial access for coronary angiography and percutaneous intervention is paralleled by an almost complete abolition … Continue reading →
The post Radial Access For Coronary Angiography Can Reduce Bleeding and Mortality appeared first on MedicalResearch.com.
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Dr. Giuseppe Andò. (2015) Radial Access For Coronary Angiography Can Reduce Bleeding and Mortality . MedicalResearch.com. info:/
MedicalResearch.com Interview with: Dr Will Herrington MD, MRCP and Dr Natalie Staplin PhD Nuffield Department of Population Health, University of Oxford Oxford, UK Medical Research: What is the background for this study? What are the main findings? Response: These analyses … Continue reading →
The post Study Examines Higher Systolic Blood Pressure and Kidney Disease Progression appeared first on MedicalResearch.com.
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Dr Will Herrington MD, MRCP and, & Dr Natalie Staplin PhD. (2015) Study Examines Higher Systolic Blood Pressure and Kidney Disease Progression. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Dr. Wanpen Vongpatanasin MD Program Director, Hypertension Fellowship Program Professor of Internal Medicine Director of the University of Texas Southwestern Hypertension Program Medical Research: What is the background for this study? What are the main findings? Dr. Vongpatanasin: … Continue reading →
The post White Coat Hypertension Is Not Benign and Should Not Be Ignored appeared first on MedicalResearch.com.
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Dr. Wanpen Vongpatanasin MD. (2015) White Coat Hypertension Is Not Benign and Should Not Be Ignored. MedicalResearch.com. info:/
Apparently yes, at least according to today’s researchers. And you likely will be somewhat taken aback by just which group you choose to make wait. Researchers wanted to study whether the pedestrian’s race had anything to do with yielding behavior of motorists at crosswalks. They tested with 173 motorists and 6 trained male pedestrian-confederates (3 […]
Do Whites, Blacks, and Asians have different biases than Biracial adults?
Are you a White American? How Black is y........ Read more »
Goddard, T., Kahn, K., & Adkins, A. (2015) Racial bias in driver yielding behavior at crosswalks. Transportation Research Part F: Traffic Psychology and Behaviour, 1-6. DOI: 10.1016/j.trf.2015.06.002
Eager to travel to Mars? Think twice!
NASA, galactic cosmic rays, mars, space travel
Explorations of Mars with probes and spacecraft are revealing intriguing features of the Red Planet. The most recent discovery by the NASA spacecraft Mars Reconnaissance Orbiter, that liquid water very likely flows on Mars, has stirred enthusiasm among scientists who have been looking for signs of “life-as-we-know-it” on the planet for the last twenty years.
One of the major future goals of ........ Read more »
"Immune clue to preventing schizophrenia" went the BBC headline, as the paper by Peter Bloomfield and colleagues  garnered some significant media interest recently specifically tied into their findings suggesting that: "neuroinflammation is linked to the risk of psychosis and related disorders, as well as the expression of subclinical symptoms."Based on the use of "second-generation radioligand [11C]PBR28 and PET to image microglial activity in the brains of participants at ultra high risk fo........ Read more »
Bloomfield, P., Selvaraj, S., Veronese, M., Rizzo, G., Bertoldo, A., Owen, D., Bloomfield, M., Bonoldi, I., Kalk, N., Turkheimer, F.... (2015) Microglial Activity in People at Ultra High Risk of Psychosis and in Schizophrenia: An [ C]PBR28 PET Brain Imaging Study . American Journal of Psychiatry. DOI: 10.1176/appi.ajp.2015.14101358
Credit: Image courtesy of Aalto UniversityIs it possible to be “addicted” to food, much like an addiction to substances (e.g., alcohol, cocaine, opiates) or behaviors (gambling, shopping, Facebook)? An extensive and growing literature uses this terminology in the context of the “obesity epidemic”, and looks for the root genetic and neurobiological causes (Carlier et al., 2015; Volkow & Bailer, 2015).Fig. 1 (Meule, 2015). Number of scientific publications on food addiction (1990-2014........ Read more »
Castro, D., & Berridge, K. (2014) Advances in the neurobiological bases for food ‘liking’ versus ‘wanting’. Physiology , 22-30. DOI: 10.1016/j.physbeh.2014.05.022
Karlsson, H., Tuulari, J., Tuominen, L., Hirvonen, J., Honka, H., Parkkola, R., Helin, S., Salminen, P., Nuutila, P., & Nummenmaa, L. (2015) Weight loss after bariatric surgery normalizes brain opioid receptors in morbid obesity. Molecular Psychiatry. DOI: 10.1038/mp.2015.153
Meule A. (2015) Back by Popular Demand: A Narrative Review on the History of Food Addiction Research. The Yale journal of biology and medicine, 88(3), 295-302. PMID: 26339213
Following removal of immobilization, a patient recovering from an isolated uncomplicated ankle fracture does not benefit more from a supervised exercise program and advice compared with advice alone.... Read more »
Moseley AM, Beckenkamp PR, Haas M, Herbert RD, Lin CW, & EXACT Team. (2015) Rehabilitation After Immobilization for Ankle Fracture: The EXACT Randomized Clinical Trial. JAMA, 314(13), 1376-85. PMID: 26441182
Minimalist vs Maximalist Running Shoes and Achilles Tendon Loads... Read more »
Sinclair, J., Richards, J., & Shore, H. (2015) Effects of minimalist and maximalist footwear on Achilles tendon load in recreational runners. Comparative Exercise Physiology, 1-6. DOI: 10.3920/CEP150024
You may have seen the buzz around a recent study which found that atheist kids are more altruistic than religious kids. Like any study that reinforces preconceptions of a vocal group, it was social media gold dust. I want to take a critical look at it and some of the objections that have been raised [Read More...]... Read more »
Decety, J., Cowell, J., Lee, K., Mahasneh, R., Malcolm-Smith, S., Selcuk, B., & Zhou, X. (2015) The Negative Association between Religiousness and Children’s Altruism across the World. Current Biology. DOI: 10.1016/j.cub.2015.09.056
An overview of my PhD so far...... Read more »
Ottenburghs, J., Ydenberg, R., Van Hooft, P., Van Wieren, S., & Prins, H. (2015) The Avian Hybrids Project: gathering the scientific literature on avian hybridization. Ibis, 157(4), 892-894. DOI: 10.1111/ibi.12285
A new paper from British psychologists David Shanks and colleagues will add to the growing sense of a "reproducibility crisis" in the field of psychology.
The paper is called Romance, Risk, and Replication and it examines the question of whether subtle reminders of 'mating motives' (i.e. sex) can make people more willing to spend money and take risks. In 'romantic priming' experiments, participants are first 'primed' e.g. by reading a story about meeting an attractive member of the opposite s... Read more »
Shanks DR, Vadillo MA, Riedel B, Clymo A, Govind S, Hickin N, Tamman AJ, & Puhlmann LM. (2015) Romance, Risk, and Replication: Can Consumer Choices and Risk-Taking Be Primed by Mating Motives?. Journal of experimental psychology. General. PMID: 26501730
A new cholesterol-lowering vaccine leads to reductions in ‘bad’ LDL cholesterol in mice and macaques, according to research. The authors of the study, from the University of New Mexico and the National Institutes of health in the United States, say the vaccine has the potential to be a more powerful treatment than statins alone.... Read more »
Crossey, E., Amar, M., Sampson, M., Peabody, J., Schiller, J., Chackerian, B., & Remaley, A. (2015) A cholesterol-lowering VLP vaccine that targets PCSK9. Vaccine, 33(43), 5747-5755. DOI: 10.1016/j.vaccine.2015.09.044
A dozen or so solitary trees scattered within a remote part of northeastern Madagascar are all that remains of Voanioala gerardii in its natural setting.In Malagasy, the national language of the large African island, the plant is called voanio-ala. This translates to 'forest coconut', which is appropriate given that the coconut (Cocos nucifera) is one of its closer relatives. Incidentally, the genus names assigned to several other palm trees found on Madagascar (e.g. Marojejya and Raphia) w........ Read more »
Dransfield J. (1989) Voanioala (Arecoideae: Cocoeae: Butiinae), a new palm genus from Madagascar. Kew Bulletin, 44(2), 191. DOI: 10.2307/4110796
The role of inflammation in the brain is receiving increased attention in dementia and other disorders in neuroscience medicine.Dementia with Lewy bodies (DLB) is the third leading cause of dementia. This disorder has received increased attention with the finding of the condition in the autopsy of comedian and actor Robin Williams.Patrick Ejlerskov and colleagues from Denmark, Sweden, Germany and the United Kingdom recently published an informative study in the journal Cell on this topic.Cytokin........ Read more »
Ejlerskov P, Hultberg JG, Wang J, Carlsson R, Ambjørn M, Kuss M, Liu Y, Porcu G, Kolkova K, Friis Rundsten C.... (2015) Lack of Neuronal IFN-β-IFNAR Causes Lewy Body- and Parkinson's Disease-like Dementia. Cell, 163(2), 324-39. PMID: 26451483
MedicalResearch.com Interview with: Dr. Jonathan L. Silverberg MD PhD MPH Assistant Professor in Dermatology Medical Social Sciences and Preventive Medicine Northwestern University, Chicago, Illinois Medical Research: What is the background for this study? What are the main findings? Dr. Silverberg: … Continue reading →
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Dr. Jonathan L. Silverberg MD PhD MPH. (2015) Patients Eczema Receive More Preventative Health Care Services. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Xifeng Wu, M.D., Ph.D, Professor, Epidemiology Stephanie Melkonian, Ph.D University of Texas M. D. Anderson Cancer Center Medical Research: What is the background for this study? What are the main findings? Response: This study examines dietary intake … Continue reading →
The post Smoked, Charred Meat Raises Increases Carcinogens, Risk of Kidney Cancer appeared first on MedicalResearch.com.
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Xifeng Wu, M.D., Ph.D,, & Stephanie Melkonian, Ph.D. (2015) Smoked, Charring Meat Raises Increases Carcinogens, Risk of Kidney Cancer. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Lauren Cooper, MD Fellow in Cardiovascular Diseases Duke University Medical Center Duke Clinical Research Institute Medical Research: What is the background for this study? What are the main findings? Dr. Cooper: Heart failure guidelines recommend routine monitoring … Continue reading →
The post Most Heart Failure Patients on Mineralocorticoid Receptor Antagonist Don’t Receive Recommended Laboratory Tests appeared first on MedicalResearch.com.
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Lauren Cooper, MD. (2015) Most Heart Failure Patients on Mineralocorticoid Receptor Antagonist Don’t Receive Recommended Laboratory Tests. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Dr. Priscilla Kaliopi Brastianos MD Instructor, Medicine, Harvard Medical School Assistant Physician in Medicine Hematology/Oncology, Massachusetts General Hospital Medical Research: What is the background for this study? What are the main findings? Response: Craniopharyngiomas are rare brain … Continue reading →
The post BRAF Inhibitor Dramatically Shrinks Rare Brain Tumor appeared first on MedicalResearch.com.
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Dr. Priscilla Kaliopi Brastianos MD. (2015) BRAF Inhibitor Dramatically Shrinks Rare Brain Tumor. MedicalResearch.com. info:/
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