So if you are one of the bodybuilders, powerlifters, marathon runners, or just people who like to binge-eat every now and then — no judgment all you can eat pizza day is a thing I’m told telling myself — there is some bad news. If you like to preload carbs like they are the magic bullet to your workout woes, you may want to rethink it because according to a new study, it can have an acute and detrimental effect on heart function.
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Arora, P., Wu, C., Hamid, T., Arora, G., Agha, O., Allen, K., Tainsh, R., Hu, D., Ryan, R., Domian, I.... (2016) Acute Metabolic Influences on the Natriuretic Peptide System in Humans. Journal of the American College of Cardiology, 67(7), 804-812. DOI: 10.1016/j.jacc.2015.11.049
Antarctic seabirds called skuas are so clever that they can recognize individual humans after seeing them only a few times. Some Korean researchers discovered this by messing with the birds' nests and then waiting to get attacked. They're either very brave or have never watched The Birds.
The study took place on Antarctica's King George Island. The animals here didn't evolve around humans. People have only been making appearances on the island since the 1950s or so. Today 10 countr........ Read more »
Most gods that have been invented don’t give a damn about what us mortals get up to. Researchers think that belief in the few that do, the ones that can be thought of as moralising gods, might have a significant effect on behaviour. For example, more complex societies are more likely to believe in moralising [Read More...]... Read more »
Purzycki, B., Apicella, C., Atkinson, Q., Cohen, E., McNamara, R., Willard, A., Xygalatas, D., Norenzayan, A., & Henrich, J. (2016) Moralistic gods, supernatural punishment and the expansion of human sociality. Nature. DOI: 10.1038/nature16980
A group of Indian psychiatrists have raised concern over suspicious similarities between three papers published in the Indian Journal of Psychological Medicine (IJPM). Their allegations have just been published, also in the same journal.
The authors, Girish Banwari and colleagues, focus on a 2015 paper about the use of the drug modafinil in treating schizophrenia. Banwari et al. say that this article
Contains no data at all and that only one reference was cited in the bibliography. A l... Read more »
Banwari G, Karia S, Avudaiappan S, Tharayil HM, & Andrade C. (2016) Modafinil Augmentation of Atypical Antipsychotic Agents: Duplicate Publication, Self-plagiarism, Salami Publication, and Other Matters. Indian journal of psychological medicine, 38(1), 86-7. PMID: 27011415
This view has been challenged by the University of Southampton researchers Constantine Sedikides and Tim Wildschut, who have spent the past decade studying the benefits of nostalgia. Not only do they disavow its disease status, they have conducted numerous studies which suggest that nostalgia can make us more creative, open-minded and charitable. The definition of nostalgia used by Sedikides and Wildschut as a "sentimental longing for one's past" is based on the contemporary usage........ Read more »
van Tilburg, W., Sedikides, C., & Wildschut, T. (2015) The mnemonic muse: Nostalgia fosters creativity through openness to experience. Journal of Experimental Social Psychology, 1-7. DOI: 10.1016/j.jesp.2015.02.002
Here in Southern Ontario, spring is in the process of being sprung. This means warmer temperatures and lots of rain, which can bring about the appearance of various sorts of goo. That's right, goo. Time for some photos!... Read more »
Kim E, Lin Y, Kerney R, Blumenberg L, & Bishop C. (2014) Phylogenetic analysis of algal symbionts associated with four North American amphibian egg masses. PloS One, 9(11). PMID: 25393119
Why is the quest for fairness in science still relevant today?... Read more »
Holtz, B., & Harold, C. (2010) Interpersonal Justice and Deviance: The Moderating Effects of Interpersonal Justice Values and Justice Orientation. Journal of Management, 39(2), 339-365. DOI: 10.1177/0149206310390049
By guest blogger Sofia DelenivWe often want to know what’s driving other people’s actions. Does the politician who visited a refugee camp on the eve of elections truly care for the poverty-stricken? In reality of course, our mind reading skills are pretty limited and something as complex as an apparent act of altruism can disguise a huge diversity of motives. Most of the time, these motives remain entirely private to the individual – a driving force in a black box.For a new paper publ........ Read more »
Hein G, Morishima Y, Leiberg S, Sul S, & Fehr E. (2016) The brain's functional network architecture reveals human motives. Science (New York, N.Y.), 351(6277), 1074-8. PMID: 26941317
Without trying to scaremonger, it is already well known that certain anti-psychotics potentially indicated for some of the more 'challenging behaviours' associated with conditions like autism for example, carry their own important side-effects. Risperidone, one of the more commonly used medicines, has quite an extensive list of possible side-effects, some of which have been previously mentioned on this blog (see here). Increased appetite and weight gain are some of the more commonly observed sid........ Read more »
Scahill, L., Jeon, S., Boorin, S., McDougle, C., Aman, M., Dziura, J., McCracken, J., Caprio, S., Arnold, L., Nicol, G.... (2016) Weight Gain and Metabolic Consequences of Risperidone in Young Children With Autism Spectrum Disorder. Journal of the American Academy of Child . DOI: 10.1016/j.jaac.2016.02.016
Craig Venter is on a quest to find the Minimal bacterial genome. It seems the task is 70% complete now. We still don’t understand 30% of the minimum viable organism that we are able to build today, which means that, although we cannot understand what we cannot build, we need not necessarily understand what we can build.... Read more »
Hutchison, C., Chuang, R., Noskov, V., Assad-Garcia, N., Deerinck, T., Ellisman, M., Gill, J., Kannan, K., Karas, B., Ma, L.... (2016) Design and synthesis of a minimal bacterial genome. Science, 351(6280). DOI: 10.1126/science.aad6253
Tardigrades, they are cute and cuddly — okay maybe not cuddly — but they have earned their nicknames, such as as moss piglets or water bears. Mostly because they look like, well bears (although I don’t see a piglet personally). These guys are eight-legged microscopic animals that have long fascinated scientists for their ability to survive extremes of temperature, pressure, lack of oxygen, and even radiation exposure. Talk about a thrill seeker they can even survive in space, without a sui........ Read more »
Georgios Koutsovoulosa, Sujai Kumara, Dominik R. Laetsch, Lewis Stevens, Jennifer Daub Claire Conlon, Habib Maroon, Fran Thomasa, Aziz A. Aboobakerc, and Mark Blaxter. (2016) No evidence for extensive horizontal gene transfer in the genome of the tardigrade Hypsibius dujardini. PNAS. DOI: 10.1101/033464
When doing pretrial research we have occasionally had mock jurors show up who were inebriated or high (yes, even at 7:45am), hostile or disruptive, confused more than the average person or obviously hearing voices or responding to companions no one else could see. Yes. Occasionally people with obviously serious psychiatric disorders make it through the […]
Narcissists and Pronouns: “I”, “me”, “mine”
What’s that book you’re reading as you wait to be impane........ Read more »
Vilhauer, R. (2015) Inner reading voices: An overlooked form of inner speech. Psychosis, 8(1), 37-47. DOI: 10.1080/17522439.2015.1028972
I'd like to start by making one thing abundantly clear about today's post: I am not insinuating that self-injurious behaviour (SIB) accompanying autism is solely under genetic (or epigenetic) control.As I've discussed before on this blog, there are potentially many, many reasons why SIB under the umbrella of the so-called 'challenging behaviours' occurs (see here). As and when it does happen, the onus is on those significant others to turn detective before anyone immediately reaches for somethin........ Read more »
Shirley, M., Frelin, L., López, J., Jedlicka, A., Dziedzic, A., Frank-Crawford, M., Silverman, W., Hagopian, L., & Pevsner, J. (2016) Copy Number Variants Associated with 14 Cases of Self-Injurious Behavior. PLOS ONE, 11(3). DOI: 10.1371/journal.pone.0149646
A novel clinical risk score developed for the acutely concussed pediatric population has a modest ability to discriminate between those at low, medium, or high risk for persistent postconcussion symptoms at 28 days.... Read more »
Zemek R, Barrowman N, Freedman SB, Gravel J, Gagnon I, McGahern C, Aglipay M, Sangha G, Boutis K, Beer D.... (2016) Clinical Risk Score for Persistent Postconcussion Symptoms Among Children With Acute Concussion in the ED. JAMA, 315(10), 1014-25. PMID: 26954410
Dopamine is love. Dopamine is reward. Dopamine is addiction.Neuroscientists have a love/hate relationship with how this monoamine neurotransmitter is portrayed in the popular press.wwlp.comthestranger.com[The claim of vagus nerve-stimulating headphones is worth a post in its own right.]observer.com“You can fold your laundry, but you can’t fold your dopamine.”- James Cole Abrams, M.A. (in Contemplative Psychotherapy)The word dopamine has become a shorthand for positive reinforcement, whethe........ Read more »
Zalocusky, K., Ramakrishnan, C., Lerner, T., Davidson, T., Knutson, B., & Deisseroth, K. (2016) Nucleus accumbens D2R cells signal prior outcomes and control risky decision-making. Nature. DOI: 10.1038/nature17400
When most of us think maggots, we probably don’t think anything good, but maybe we should start. In a proof-of-concept study, researchers have shown that genetically engineered green bottle fly (Lucilia sericata) larvae can produce and secrete a human growth factor – a molecule that helps promote cell growth and wound healing.
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Linger, R., Belikoff, E., Yan, Y., Li, F., Wantuch, H., Fitzsimons, H., & Scott, M. (2016) Towards next generation maggot debridement therapy: transgenic Lucilia sericata larvae that produce and secrete a human growth factor. BMC Biotechnology, 16(1). DOI: 10.1186/s12896-016-0263-z
Do you haet typos? If you spot a grammo (a grammatical error), does your blood boil?
Some people are more offended by these kinds of linguistic errors than others, but why? Ann Arbor psychologists Julie E. Boland and Robin Queen examine this in a new PLOS ONE paper called If You’re House Is Still Available, Send Me an Email: Personality Influences Reactions to Written Errors in Email Messages
The authors recruited 83 volunteers (on MTurk) and asked them to imagine that they'd placed an... Read more »
Boland JE, & Queen R. (2016) If You're House Is Still Available, Send Me an Email: Personality Influences Reactions to Written Errors in Email Messages. PloS one, 11(3). PMID: 26959823
No matter how much I like modeling for the sake of modeling, or science for the sake of science, working in a hospital adds some constraints. At some point people look over at you measuring games in the Petri dish and ask “why are you doing this?” They expect an answer that involves something that […]... Read more »
Gatenby, R.A., & Gawlinski, E.T. (2003) The glycolytic phenotype in carcinogenesis and tumor invasion: insights through mathematical models. Cancer Research, 63(14), 3847-54. PMID: 12873971
Last month, we spoke of our vision of the future of humanity here at the lab. It makes sense that humanity would one-day step away from the static, non-living computer constructs we have designed. Moving us instead towards an organic alternative, one that can be readily repaired, replaced, or changed. While we cannot pretend to know what the future may hold, a new discovery helps bolster the stance we presented.
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Lampa-Pastirk, S., Veazey, J., Walsh, K., Feliciano, G., Steidl, R., Tessmer, S., & Reguera, G. (2016) Thermally activated charge transport in microbial protein nanowires. Scientific Reports, 23517. DOI: 10.1038/srep23517
'The disrupted connectivity hypothesis of autism spectrum disorders: Time for the next phase in research' went the title of the paper by Roma Vasa and colleagues .Disrupted connectivity by the way, refers to the idea that "deficiencies in the way the brain coordinates and synchronizes activity amongst different regions may account for the clinical symptoms of ASD [autism spectrum disorders]." Picture if you will, the brain as a serious of telephone wires all connecting different parts of........ Read more »
Vasa, R., Mostofsky, S., & Ewen, J. (2016) The disrupted connectivity hypothesis of autism spectrum disorders: Time for the next phase in research. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. DOI: 10.1016/j.bpsc.2016.02.003
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