Post List

  • July 27, 2016
  • 07:20 AM
  • 98 views

The Nature of Science of Nature

by Mark Lasbury in As Many Exceptions As Rules

One the tenets of science is that hypotheses can't be proved, only disproved. But medical journals do not publish negative data, even though this is often helpful to scientists and physicians. A recent TED Talk by Ben Goldacre illustrates this point in the context of drug studies. In a bigger sense – is this really the only way to do science; to follow this one scientific method?... Read more »

Ben Goldacre. (2012) What doctors don't know about the drugs they prescribe. TED MED. info:/

  • July 27, 2016
  • 04:30 AM
  • 88 views

We’ll Ask the Question Again? Surgery or Nonoperative Treatment?

by Kyle Harris in Sports Medicine Research (SMR): In the Lab & In the Field

Patients who sustained an anterior cruciate ligament (ACL) rupture were more likely to develop secondary meniscal injury and arthritis when compared to a matched cohort. Specifically, those that were treated nonoperatively or with delayed surgery may be more likely to develop secondary meniscal injury, develop arthritis, and be in need of a total knee replacement when compared with those patients treated with early surgery.... Read more »

Sanders, T., Kremers, H., Bryan, A., Fruth, K., Larson, D., Pareek, A., Levy, B., Stuart, M., Dahm, D., & Krych, A. (2016) Is Anterior Cruciate Ligament Reconstruction Effective in Preventing Secondary Meniscal Tears and Osteoarthritis?. The American Journal of Sports Medicine, 44(7), 1699-1707. DOI: 10.1177/0363546516634325  

  • July 27, 2016
  • 03:44 AM
  • 98 views

Blood glutamate levels in autism meta-analysed

by Paul Whiteley in Questioning Answers

"The meta-analysis provided evidence for higher blood glutamate levels in ASD [autism spectrum disorder]."That was the research bottom-line reported by Zhen Zheng and colleagues [1] (open-access available here) who surveyed the current peer-reviewed science literature in this area and found something to see based on: "Twelve studies involving 880 participants and 446 incident cases."Drawing on the idea that glutamate is a rather important amino acid that plays a role in various biological p........ Read more »

  • July 26, 2016
  • 04:22 PM
  • 122 views

The mysterious fart

by Dr. Jekyll in Lunatic Laboratories

Everyone does it ...no, not poop, but fart. Passing gas, fuming, crop dusting, cracking a rat -- no matter what you call it -- everyone fart, but why? Researchers have published an article devoted to the review of gaseous neurotransmitters of microbial origin and their role in the human body.

... Read more »

  • July 26, 2016
  • 09:22 AM
  • 102 views

Fungi found flourishing following fire

by Rosin Cerate in Rosin Cerate

Morels and several other fungi (all members of the order Pezizales) are known to produce their mushrooms in recently burned soil, whether it's the result of a nice little campfire or an entire forest going up in smoke. The fire creates the right conditions for the fungus, which lies beneath the ground and so protected from flames and heat, to send up mushrooms. These mushrooms release spores into the environment, and the circle of life continues ever onward.In the case of morels, it's thought a ........ Read more »

  • July 26, 2016
  • 03:41 AM
  • 109 views

Probiotics degrading gluten peptides - part 2

by Paul Whiteley in Questioning Answers

I going to assume that readers have some background knowledge about probiotics, gut bacteria, bacterial dysbiosis and coeliac disease before reading this post. I'd love to be able to give detailed descriptions of each here but fear that this would turn a short post into a much longer one...So... in a previous post titled: 'Probiotics degrading gluten peptides?' I covered the potentially important suggestion that certain types of bacteria might have the ability to breakdown (degrade) immunog........ Read more »

  • July 25, 2016
  • 09:04 PM
  • 108 views

Wave that claw: how male crabs attract mates

by Emily Makowski in Sextraordinary!

Male Ilyoplax pusilla crabs wave their claws in the air to attract females, but why do different-sized males spend different amounts of time waving? The answer lies in research published this year. ... Read more »

  • July 25, 2016
  • 04:51 PM
  • 110 views

Restiffic Foot Wrap for Restless Legs Syndrome

by Craig Payne in Running Research Junkie

Restiffic Foot Wrap for Restless Legs Syndrome... Read more »

  • July 25, 2016
  • 04:40 PM
  • 106 views

I know it is only a pilot study, but …. injuries in minimalist runners

by Craig Payne in Running Research Junkie

I know it is only a pilot study, but …. injuries in minimalist runners

... Read more »

Ostermann, K., Ridpath, L., & Hanna, J. (2016) Self-Reported Minimalist Running Injury Incidence and Severity: A Pilot Study. The Journal of the American Osteopathic Association, 116(8), 512. DOI: 10.7556/jaoa.2016.104  

  • July 25, 2016
  • 03:38 PM
  • 92 views

Embryonic gene Nanog reverses aging in adult stem cells

by Dr. Jekyll in Lunatic Laboratories

The fountain of youth may reside in an embryonic stem cell gene named Nanog. In a series of experiments, the gene kicked into action dormant cellular processes that are key to preventing weak bones, clogged arteries and other telltale signs of growing old. The findings also show promise in counteracting premature aging disorders such as Hutchinson-Gilford progeria syndrome.

... Read more »

  • July 25, 2016
  • 03:37 AM
  • 111 views

Risk of cancer in mums of children with autism

by Paul Whiteley in Questioning Answers

I very carefully approach the findings reported by Jennifer Fairthorne and colleagues [1] today detailing "the occurrence of hospital admissions and treatment/services for cancer in mothers of children with ASD [autism spectrum disorder] with or without ID [intellectual disability] compared with other mothers." Appreciating that families touched by autism probably have enough on their plate without additional talk about the 'big C', I do however think that this kind of r........ Read more »

  • July 24, 2016
  • 03:29 PM
  • 134 views

Researchers temporarily turn off brain area to better understand function

by Dr. Jekyll in Lunatic Laboratories

Capitalizing on experimental genetic techniques, researchers have demonstrated that temporarily turning off an area of the brain changes patterns of activity across much of the remaining brain. The research suggests that alterations in the functional connectivity of the brain in humans may be used to determine the sites of pathology in complex disorders such as schizophrenia and autism.

... Read more »

  • July 24, 2016
  • 04:45 AM
  • 133 views

Week 29 In Review: Open-Access Science | 18 to 25 July

by TakFurTheKaffe in Tak Fur The Kaffe

Cave art, wild fires, new dinosaur with teeny T-rex arms, thirsty trees and a new method to create hydrogen from grass. Here are five of the latest scientific studies published open-access this week.... Read more »

Cooper, J., Samson, A., Nieves, M., Lace, M., Caamaño-Dones, J., Cartwright, C., Kambesis, P., & Frese, L. (2016) ‘The Mona Chronicle’: the archaeology of early religious encounter in the New World. Antiquity, 90(352), 1054-1071. DOI: 10.15184/aqy.2016.103  

Nagra, G., Treble, P., Andersen, M., Fairchild, I., Coleborn, K., & Baker, A. (2016) A post-wildfire response in cave dripwater chemistry. Hydrology and Earth System Sciences, 20(7), 2745-2758. DOI: 10.5194/hess-20-2745-2016  

Caravaca, A., Jones, W., Hardacre, C., & Bowker, M. (2016) H production by the photocatalytic reforming of cellulose and raw biomass using Ni, Pd, Pt and Au on titania . Proceedings of the Royal Society A: Mathematical, Physical and Engineering Science, 472(2191), 20160054. DOI: 10.1098/rspa.2016.0054  

  • July 23, 2016
  • 05:30 PM
  • 132 views

Brain activity and response to food cues differ in severely obese women

by Dr. Jekyll in Lunatic Laboratories

The brain's reward centers in severely obese women continue to respond to food cues even after they've eaten and are no longer hungry, in contrast to their lean counterparts. The study compared attitudes and the brain activity of 15 severely obese women (those with a body mass index greater than 35) and 15 lean women (those with a BMI under 25).

... Read more »

Puzziferri, N., Zigman, J., Thomas, B., Mihalakos, P., Gallagher, R., Lutter, M., Carmody, T., Lu, H., & Tamminga, C. (2016) Brain imaging demonstrates a reduced neural impact of eating in obesity. Obesity, 24(4), 829-836. DOI: 10.1002/oby.21424  

  • July 23, 2016
  • 09:41 AM
  • 128 views

A New Map of the Brain: What Does It Mean?

by Neuroskeptic in Neuroskeptic_Discover

A new Nature paper has earned a lot of media attention, unusually given that it's a fairly technical and 'basic' piece of neuroscience. In the paper, researchers Matthew F. Glasser and colleagues present a new parcellation (or map) of the human cerebral cortex, breaking the cortex down into 180 areas per hemisphere - many more than conventional maps.



But is this, as Nature dubbed it, "the ultimate brain map"?

To generate their map, Glasser et al. first downloaded 210 people's data from... Read more »

Glasser MF, Coalson TS, Robinson EC, Hacker CD, Harwell J, Yacoub E, Ugurbil K, Andersson J, Beckmann CF, Jenkinson M.... (2016) A multi-modal parcellation of human cerebral cortex. Nature. PMID: 27437579  

  • July 23, 2016
  • 04:17 AM
  • 140 views

On probiotics and irritable bowel syndrome (IBS)

by Paul Whiteley in Questioning Answers

Granted, I am taking a slight departure from the material typically discussed on this blog by introducing the paper by Yan Zhang and colleagues [1] who reported the findings of a meta-analysis examining "the efficacy of different probiotic types, doses and treatment durations in IBS [irritable bowel syndrome] patients diagnosed by Rome III criteria via a meta-analysis of randomized controlled trials (RCTs)." The results however - "Probiotics are an effective pharmacological t........ Read more »

  • July 22, 2016
  • 03:38 PM
  • 146 views

When it comes to empathy, don't always trust your gut

by Dr. Jekyll in Lunatic Laboratories

Ever feel like someone is hiding something? Or maybe you suddenly feel like you can't trust a co-worker. The feeling may seem logical, but is empathy the result of gut intuition or careful reasoning? Research suggests that, contrary to popular belief, the latter may be more the case.

... Read more »

  • July 22, 2016
  • 12:25 PM
  • 132 views

Video of Evaporating Booze Droplet Looks Like a Tiny Planet

by Elizabeth Preston in Inkfish



Most of us don't give much thought to drops of liquid that end up outside our drinking glasses. But physicists care a lot about liquid droplets, and study their whole lifespans—from the first splash or drip to the moment a drop disappears.

Liquids that contain three different substances, though, haven't been studied as much. Detlef Lohse, a physicist at the University of Twente in the Netherlands, and his colleagues took a deep dive into one such liquid: ouzo.

Ouzo is a mixture of wate... Read more »

Tan H, Diddens C, Lv P, Kuerten JG, Zhang X, & Lohse D. (2016) Evaporation-triggered microdroplet nucleation and the four life phases of an evaporating Ouzo drop. Proceedings of the National Academy of Sciences of the United States of America. PMID: 27418601  

  • July 22, 2016
  • 11:50 AM
  • 136 views

Altruistic people have more sex

by BPS Research Digest in BPS Research Digest

People who perform regular altruistic acts like giving blood also tend to have more sex.Viewed through the lens of evolutionary psychology, altruism takes some explaining. In a dog eat dog world, it seems like a risky, indulgent habit. Yet we are only alive today because our distant ancestors were successful at reproducing – and the fact many of us have inherited their altruistic tendencies suggests that being altruistic gave them some kind of survival or reproductive advantage.One idea i........ Read more »

Arnocky, S., Piché, T., Albert, G., Ouellette, D., & Barclay, P. (2016) Altruism predicts mating success in humans. British Journal of Psychology. DOI: 10.1111/bjop.12208  

  • July 22, 2016
  • 09:01 AM
  • 124 views

Update on clinical trials and treatments for RCC

by Joana Guedes in BHD Research Blog

Renal cell carcinoma (RCC) is the most common type of kidney cancer and although the majority of cases are sporadic approximately 3% of cases are caused by genetic conditions such as BHD, VHL, HLRCC and TSC (Randall et al., 2014). These inherited forms of RCC have provided great insights into sporadic cancer genetics. BHD patients can develop multiple kidney tumours. In most cases these tumours are small local RCCs that can be surgically removed. However, these treatments are not without risk,........ Read more »

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