Post List

  • July 4, 2015
  • 05:19 AM
  • 60 views

A viral 'cause' of obesity?

by Paul Whiteley in Questioning Answers

I must thank Leah Hardy (@LeahFHardy) for bringing to my attention the paper by Qinglong Shang and colleagues [1] (open-access available here) reporting that: "Ad36 [Human adenovirus 36] infection is associated with an increased risk of obesity development."Based on a meta-analysis of the available research literature examining whether Ad-36 - "a nonenveloped icosahedral virus comprised of double-stranded DNA and is one of 56 serotypes in 7 subgroups of human adenoviruses" - might........ Read more »

  • July 3, 2015
  • 04:37 PM
  • 82 views

REM sleep critical for young brain development; medication interferes

by Dr. Jekyll in Lunatic Laboratories

Rapid eye movement or REM sleep actively converts waking experiences into lasting memories and abilities in young brains reports a new study. The finding broadens the understanding of children’s sleep needs and calls into question the increasing use of REM-disrupting medications such as stimulants and antidepressants.

... Read more »

Michelle C. Dumoulin Bridi, Sara J. Aton, Julie Seibt, Leslie Renouard, Tammi Coleman1, & Marcos G. Frank. (2015) Rapid eye movement sleep promotes cortical plasticity in the developing brain. Science Advances. info:/10.1126/sciadv.1500105

  • July 3, 2015
  • 04:05 PM
  • 62 views

Novel DNA repair mechanism brings new horizons

by Dr. Jekyll in Lunatic Laboratories

The DNA molecule is chemically unstable giving rise to DNA lesions of different nature. That is why DNA damage detection, signaling and repair, collectively known as the DNA damage response, are needed. A group of researchers discovered a new mechanism of DNA repair, which opens up new perspectives for the treatment and prevention of neurodegenerative diseases.... Read more »

Nikolay A. Pestov, Nadezhda S. Gerasimova, Olga I. Kulaeva, & Vasily M. Studitsky. (2015) Structure of transcribed chromatin is a sensor of DNA damage. Science Advances. info:/10.1126/sciadv.1500021

  • July 3, 2015
  • 11:47 AM
  • 74 views

Smile at a party and people are more likely to remember seeing your face there

by BPS Research Digest in BPS Research Digest

When you smile at a party, your facial expression is emotionally consistent with the happy context and as a consequence other guests will in future be more likely to remember that they've seen your face before, and where you were when they saw you. That's according to a team of Italian researchers led by Stefania Righi who have explored how memory for a face is affected by the emotion shown on that face and the congruence between that emotional expression and its surrounding context.The research........ Read more »

  • July 3, 2015
  • 11:45 AM
  • 43 views

Warming Climate May Not Reduce Winter Mortality

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Prof. Patrick L Kinney Ph.D. Professor of Environmental Health Sciences and Director, Columbia Climate and Health Program Mailman School of Public Health Columbia University, New York, NY Medical Research: What is the background for this study? Dr. Kinney: … Continue reading →
The post Warming Climate May Not Reduce Winter Mortality appeared first on MedicalResearch.com Medical Research Interviews and News.
... Read more »

Prof. Patrick L Kinney Ph.D., & Professor of Environmental Health Sciences. (2015) Warming Climate May Not Reduce Winter Mortality. MedicalResearch.com. info:/

  • July 3, 2015
  • 09:55 AM
  • 68 views

Evidence for "Unconscious Learning" Questioned

by Neuroskeptic in Neuroskeptic_Discover

Can we learn without being aware of what we're learning? Many psychologists say that 'unconscious', or implicit, learning exists.

But in a new paper, London-based psychologists Vadillo, Konstantinidis, and Shanks call the evidence for this into question.



Vadillo et al. focus on one particular example of implicit learning, the contextual cueing paradigm. This involves a series of stimulus patterns, each consisting of a number of "L" shapes and one "T" shape in various orientations. For ... Read more »

  • July 3, 2015
  • 09:13 AM
  • 46 views

Diabetes Medication Reduced Weight and Improved Metabolic Parameters in Obese Patients

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Dr. F. Xavier Pi–Sunyer MD Division of Endocrinology and Obesity Research Center Columbia University, New York Medical Research: What is the background for this study? What are the main findings? Dr. Pi-Sunye: In a large randomized trial, … Continue reading →
The post Diabetes Medication Reduced Weight and Improved Metabolic Parameters in Obese Patients appeared first on MedicalResearch.com Medical Research Interviews and News.
... Read more »

Dr. F. Xavier Pi-Sunyer MD, & Division of Endocrinology and Obesity Research Center. (2015) Diabetes Medication Reduced Weight and Improved Metabolic Parameters in Obese Patients. MedicalResearch.com. info:/

  • July 3, 2015
  • 08:54 AM
  • 40 views

Low Testosterone Linked To Obesity and Depression In Men

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Michael S. Irwig MD Division of Endocrinology Medical Faculty Associates George Washington University Medical Research: What is the background for this study? What are the main findings? Response: Many factors are associated with lower testosterone levels and … Continue reading →
The post Low Testosterone Linked To Obesity and Depression In Men appeared first on MedicalResearch.com Medical Research Interviews and News.
... Read more »

Michael S. Irwig MD Division of Endocrinology Medical Faculty Associates. (2015) Low Testosterone Linked To Obesity and Depression In Men. MedicalResearch.com. info:/

  • July 3, 2015
  • 08:15 AM
  • 38 views

Male Kangaroos' Arms Evolved to Pound the Crap out of Each Other

by Elizabeth Preston in Inkfish



When you look at a kangaroo or a wallaby, it's obvious the animal is well built for bouncing around the outback. What may be less obvious is that its arms are built for fighting—if it's male, that is. Males of these species have disproportionately long arm bones. And the more brawling a species does, the more exaggerated the difference between the beefy-armed males and their normal-limbed mates.

To understand this evolutionary quirk, we'll need to review the rules of fighting in wallabie........ Read more »

  • July 3, 2015
  • 07:02 AM
  • 14 views

Trustworthiness, real adulthood, cat videos and how open you are to experiences 

by Rita Handrich in The Jury Room

Here’s another installment of things we think you might want to know but to which we don’t wish to devote an entire blog post. Keep reading to have tidbits worthy of sound bytes over drinks. The onset of ‘real’ adulthood Five years ago we were distressed to discover that middle age begins at 35 and […]

Related posts:
There is a “naive faith in the trustworthiness of brain imaging data”
“I’ve got proof I’m open-minded!”: Inventing racist roads not taken
Your online av........ Read more »

  • July 3, 2015
  • 06:06 AM
  • 68 views

A new tissue-specific FLCN-deficient mouse model of renal tumourigenesis

by Danielle Stevenson in BHD Research Blog

Animal models can be useful for understanding disease pathology and as preclinical models for drug testing. As BHD patients develop renal cell carcinomas (RCCs) of varied histologies, associated with a loss of FLCN, BHD animal models could be used to study of a wide range of renal cancer subtypes. Current BHD mouse models include kidney-specific Flcn-knockouts (Chen et al., 2008, Baba et al., 2008) and ubiquitous knockouts (Hasumi et al., 2009, Hartman et al., 2009, Hudon et al., 2010). The form........ Read more »

Chen J, Huang D, Rubera I, Futami K, Wang P, Zickert P, Khoo SK, Dykema K, Zhao P, Petillo D.... (2015) Disruption of tubular Flcn expression as a mouse model for renal tumor induction. Kidney international. PMID: 26083655  

  • July 3, 2015
  • 06:02 AM
  • 96 views

5 Tips For Better Sleep

by Elisabeth Buhl Thubron in United Academics

Adding some ‘worry time’ to your day could work better than pills.... Read more »

  • July 3, 2015
  • 05:15 AM
  • 70 views

Here be values (in the brain): how the ventral striatum participates in decision-making

by Pierre Megevand in Neuroscience and Medicine

A new research article shows that the ventral striatum includes a representation of the value attributed to potential choices in a gambling task, and of the decision eventually reached.... Read more »

  • July 3, 2015
  • 04:56 AM
  • 57 views

Vitamin D metabolic gene variants and risk for autism

by Paul Whiteley in Questioning Answers

I was really rather happy to see the "preliminary evidence" reported by Rebecca Schmidt and colleagues [1] when it came to examining whether selected vitamin D metabolic gene variants might show linkage to autism spectrum disorder (ASD) based on data derived from the CHARGE initiative.For quite a while now I've discussed the various peer-reviewed science on the topic of vitamin D deficiency / insufficiency with autism in mind on this blog (see here and see here for example). Specifically, h........ Read more »

Schmidt RJ, Hansen RL, Hartiala J, Allayee H, Sconberg JL, Schmidt LC, Volk HE, & Tassone F. (2015) Selected vitamin D metabolic gene variants and risk for autism spectrum disorder in the CHARGE Study. Early human development, 91(8), 483-489. PMID: 26073892  

  • July 2, 2015
  • 06:50 PM
  • 59 views

You are here: Home › Injury › Foot Strike Pattern and Injury Rates Foot Strike Pattern and Injury Rates

by Craig Payne in Running Research Junkie

You are here: Home › Injury › Foot Strike Pattern and Injury Rates
Foot Strike Pattern and Injury Rates... Read more »

  • July 2, 2015
  • 02:54 PM
  • 31 views

Study Compares Two Surgical Techniques To Relieve Migraine Headaches

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Dr. Bahman Guyuron MD Cleveland and Lyndhurst, Ohio From the Department of Plastic Surgery, University Hospital Case Medical Center; and the American Migraine Center Medical Research: What is the background for this study? Dr. Guyuron: Through several … Continue reading →
The post Study Compares Two Surgical Techniques To Relieve Migraine Headaches appeared first on MedicalResearch.com Medical Research Interviews and News.
... Read more »

Dr. Bahman Guyuron MD, & Cleveland and Lyndhurst. (2015) Study Compares Two Surgical Techniques To Relieve Migraine Headaches. MedicalResearch.com. info:/

  • July 2, 2015
  • 02:18 PM
  • 32 views

Biomarker Predicts Bladder Cancer Response To Treatment

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Chao Cheng, Ph.D. Assistant Professor Department of Genetics Institute for Quantitative Biomedical Sciences Geisel School of Medicine at Dartmouth Hanover NH, 03755 Medical Research: What is the background for this study? Dr. Cheng: Bladder cancer is a … Continue reading →
The post Biomarker Predicts Bladder Cancer Response To Treatment appeared first on MedicalResearch.com Medical Research Interviews and News.
... Read more »

Chao Cheng, Ph.D., & Assistant Professor. (2015) Biomarker Predicts Bladder Cancer Response To Treatment. MedicalResearch.com. info:/

  • July 2, 2015
  • 12:57 PM
  • 66 views

Freezing single atoms to absolute zero with microwaves brings quantum technology closer

by Dr. Jekyll in Lunatic Laboratories

Physicists at the University of Sussex have found a way of using everyday technology found in kitchen microwaves and mobile telephones to bring quantum physics closer to helping solve enormous scientific problems that the most powerful of today’s supercomputers cannot even begin to embark upon.... Read more »

Weidt, S., Randall, J., Webster, S., Standing, E., Rodriguez, A., Webb, A., Lekitsch, B., & Hensinger, W. (2015) Ground-State Cooling of a Trapped Ion Using Long-Wavelength Radiation. Physical Review Letters, 115(1). DOI: 10.1103/PhysRevLett.115.013002  

  • July 2, 2015
  • 11:57 AM
  • 54 views

Digesting bread and pasta can release biologically active molecules

by Dr. Jekyll in Lunatic Laboratories

Biologically active molecules released by digesting bread and pasta can survive digestion and potentially pass through the gut lining, suggests new research. The study reveals the molecules released when real samples of bread and pasta are digested, providing new information for research into gluten sensitivity.... Read more »

  • July 2, 2015
  • 09:00 AM
  • 47 views

Why Should You Care How Bacteria Fight Viruses?

by Bill Sullivan in The 'Scope

Research into how bacteria fight viruses has spurred a revolution in genetic engineering referred to as "CRISPR". CRISPR provides unprecedented ways to easily modify the genome of any living creature, including humans.... Read more »

Garneau, J., Dupuis, M., Villion, M., Romero, D., Barrangou, R., Boyaval, P., Fremaux, C., Horvath, P., Magadán, A., & Moineau, S. (2010) The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA. Nature, 468(7320), 67-71. DOI: 10.1038/nature09523  

Horie, M., Honda, T., Suzuki, Y., Kobayashi, Y., Daito, T., Oshida, T., Ikuta, K., Jern, P., Gojobori, T., Coffin, J.... (2010) Endogenous non-retroviral RNA virus elements in mammalian genomes. Nature, 463(7277), 84-87. DOI: 10.1038/nature08695  

Baltimore, D., Berg, P., Botchan, M., Carroll, D., Charo, R., Church, G., Corn, J., Daley, G., Doudna, J., Fenner, M.... (2015) A prudent path forward for genomic engineering and germline gene modification. Science, 348(6230), 36-38. DOI: 10.1126/science.aab1028  

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