Post List

  • July 30, 2014
  • 08:10 AM
  • 157 views

Does Life Come In XXXS?

by Mark Lasbury in As Many Exceptions As Rules

Is there a minimum size for life? How would you measure it, cell volume or genome size? People do both. The current minimum example of life is Mycoplasma genitalium, at just 200 nm by 600 nm in well-fed cultures. M. genitalium also has the smallest known genome for a free-living organism (520 genes, we have about 27,000). Some organisms have fewer genes (137 or so) but are endosymbionts, so they can get away with trashing some of their DNA. New research shows that M. genitalium is a pathogenic o........ Read more »

Manhart LE. (2013) Mycoplasma genitalium: An emergent sexually transmitted disease?. Infectious disease clinics of North America, 27(4), 779-92. PMID: 24275270  

Gibson DG, Glass JI, Lartigue C, Noskov VN, Chuang RY, Algire MA, Benders GA, Montague MG, Ma L, Moodie MM.... (2010) Creation of a bacterial cell controlled by a chemically synthesized genome. Science (New York, N.Y.), 329(5987), 52-6. PMID: 20488990  

  • July 30, 2014
  • 07:32 AM
  • 109 views

Potentially habitable exoplanets found

by Jeffrey Daniels in United Academics

Two systems in the cosmic realm that are the closest to Earth found so far. At half the speed of light we can visit them within a single human lifetime.... Read more »

Anglada-Escude, G., Arriagada, P., Tuomi, M., Zechmeister, M., Jenkins, J., Ofir, A., Dreizler, S., Gerlach, E., Marvin, C., Reiners, A.... (2014) Two planets around Kapteyn's star: a cold and a temperate super-Earth orbiting the nearest halo red dwarf. Monthly Notices of the Royal Astronomical Society: Letters, 443(1). DOI: 10.1093/mnrasl/slu076  

  • July 30, 2014
  • 07:02 AM
  • 68 views

We agree and thus, I am certain we shall prevail

by Doug Keene in The Jury Room

The American Bar Association is seeking nominations until August 8, 2014 to help it decide on the Top 100 law blogs (“Blawgs”). We have been in the ABA Top 100 for the past 4 years and would like to make it 5! If you like this blog, please nominate us (it’s fast and free) here. THANKS! […]

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Politics and prejudice? Nope. It’s about........ Read more »

  • July 30, 2014
  • 06:59 AM
  • 105 views

Efficient Room-Temperature Phosphorescent OLEDs Developed

by dailyfusion in The Daily Fusion

The team of Jinsang Kim, a professor of materials science and engineering and chemical engineering at the University of Michigan, developed bright, metal-free, organic, phosphorescent light emitters.... Read more »

  • July 30, 2014
  • 05:35 AM
  • 100 views

When the cuddle hormone turns nasty - oxytocin linked with violent intentions

by BPS Research Digest in BPS Research Digest

For many years, the hormone oxytocin was caricatured as the source of all human goodness - trust, altruism, love, and morality. Among the findings that contributed to this picture were the discovery that sniffing oxytocin increases people's trust and generosity in financial games; that it aids face recognition; and that its release is associated with maternal bonding; and with orgasm.However, the picture has grown a lot more complicated of late, with findings showing that oxytocin........ Read more »

  • July 30, 2014
  • 05:27 AM
  • 68 views

Subduing the Hive Mind: An enemy’s enemy could become an unlikely friend

by socgenmicro in Microbe Post

Leafcutter ants form some of the biggest, most remarkable animal societies on Earth, living in sprawling colonies of up to 8 million individuals. These ants harvest more greenery in South American rainforests than any other animal, consuming almost 20% of … Continue reading →... Read more »

  • July 30, 2014
  • 05:23 AM
  • 18 views

Wet get drier (eventually)?

by Ed Hawkins in Climate Lab Book

A prevailing paradigm of how rainfall patterns will change on a warming Earth is that the hydrological cycle strengthens causing wet regions to get wetter and dry regions to get drier. However, this is not always the case: Hawkins, Joshi … Continue reading →... Read more »

Hawkins, E., Joshi, M., & Frame, D. (2014) Wetter then drier in some tropical areas. Nature Climate Change, 4(8), 646-647. DOI: 10.1038/nclimate2299  

  • July 30, 2014
  • 04:52 AM
  • 88 views

Immunological effects from risperidone treatment in autism

by Paul Whiteley in Questioning Answers

The findings from Jai Eun Choi and colleagues [1] suggesting that use of the antipsychotic risperidone may impact on levels of certain cytokines - messenger cells of the immune system - in some cases of autism spectrum disorder (ASD) grabbed my attention recently. I've always been pretty interested in the complexity of the immune system when it comes to something like autism (see here) as well as the various examples of how many of the medications used to 'manage' aspects of autis........ Read more »

Choi JE, Widjaja F, Careaga M, Bent S, Ashwood P, & Hendren RL. (2014) Change in Plasma Cytokine Levels During Risperidone Treatment in Children with Autism. Journal of child and adolescent psychopharmacology. PMID: 24828014  

  • July 30, 2014
  • 12:05 AM
  • 60 views

The Devil Is In The Details…If You Can Get The Details Out

by Kyle Harris in Sports Medicine Research (SMR): In the Lab & In the Field

Over 75% of surveyed collegiate athletes, who believed they sustained a concussion in the past year, reported not seeking proper medical attention for that concussion. The most common reason athletes reported not seeking proper medical attention was not believing the concussion was severe enough to warrant stopping the activity to seek out a medical professional.... Read more »

  • July 29, 2014
  • 07:01 PM
  • 53 views

Gabapentin and pregabalin misuse

by DJMac in Recovery Review

  Gabapentin and pregabalin misuse are problems that are not going to go away. My post on gabapentin is one of the most-read on this site. While these are useful medicines, workers in drug treatment and support see patients regularly on gabapentin or pregabalin who have misused the drugs or who are misusing them. Guidance is [...]
The post Gabapentin and pregabalin misuse appeared first on Recovery Review.
... Read more »

  • July 29, 2014
  • 05:00 PM
  • 75 views

A simple and useable classification of software by Aral Balkan via Wuthering Bytes

by Duncan Hull in O'Really?

It’s getting pretty hard to do anything these days that doesn’t involve software. Our governments, businesses, laboratories, personal lives and entertainment would look very different without the software that makes them tick. How can we classify all this software to make sense of it all? The likes of this huge list of software categories on wikipedia are pretty bewildering, and projects such as the Software Ontology (SWO) [1] are attempting to make sense of swathes of software too. ........ Read more »

  • July 29, 2014
  • 01:15 PM
  • 102 views

Can’t Handle the Stress? Blame your Brain

by Gabriel in Lunatic Laboratories

Do you rise to the occasion, or do you fold under the pressure? No matter which side of the fence you’re, you can thank [or blame] your brain. Some people […]... Read more »

  • July 29, 2014
  • 12:32 PM
  • 95 views

Are silly superstitions useful because they are silly?

by neuroecology in Neuroecology

(Attention warning: massive speculation ahead.) Auguries often seem made up, useless. Is that why they are useful? Dove figured that the birds must be serving as some kind of ecological indicator. Perhaps they gravitated toward good soil, or smaller trees, or some other useful characteristic of a swidden site. After all, the Kantu’ had been […]... Read more »

  • July 29, 2014
  • 12:02 PM
  • 97 views

When Mom and Dad Have Different Migratory Routes, Kids Fly Right Down the Middle

by Elizabeth Preston in Inkfish

It sounds like the setup to a bad joke told by zoologists: What do you get when you cross a bird that always flies to the west with one that always flies east? But the punch line is weirder than you’d guess. Birds’ migratory routes are partly coded into their DNA. A baby that inherits […]The post When Mom and Dad Have Different Migratory Routes, Kids Fly Right Down the Middle appeared first on Inkfish.... Read more »

  • July 29, 2014
  • 11:55 AM
  • 109 views

Japanese Encephalitis Virus, Coronavirus, Autophagy, and the ER stress response

by thelonevirologist in Virology Tidbits

The accumulation of misfolded proteins in the ER lumen induces a stress response commonly known as the Unfolded Protein Response (UPR) or ER stress response, an adaptive signalling pathway increasing the expression of ER chaperones, inhibiting mRNA translation, and stimulating ER associated degradation (ERAD) of accumulated proteins. The degradation via the ERAD pathway in particular requires the formation of double membrane vesicles -more commonly referred to as autophagosomes - which subsequen........ Read more »

Rzymski T, Milani M, Pike L, Buffa F, Mellor HR, Winchester L, Pires I, Hammond E, Ragoussis I, & Harris AL. (2010) Regulation of autophagy by ATF4 in response to severe hypoxia. Oncogene, 29(31), 4424-35. PMID: 20514020  

Li JK, Liang JJ, Liao CL, & Lin YL. (2012) Autophagy is involved in the early step of Japanese encephalitis virus infection. Microbes and infection / Institut Pasteur, 14(2), 159-68. PMID: 21946213  

Cottam EM, Whelband MC, & Wileman T. (2014) Coronavirus NSP6 restricts autophagosome expansion. Autophagy, 10(8). PMID: 24991833  

  • July 29, 2014
  • 11:17 AM
  • 134 views

Treating Sleep Problems Following Traumatic Brain Injury

by William Yates, M.D. in Brain Posts

Sleep problems are common following traumatic brain injury (TBI).In a previous post, I reviewed a study of the risk factors for sleep disorders following TBI.The most severe TBI is a risk factor for hypersomnia. Anxiety and depression following TBI increase risk for insomnia complaints.Few large studies of treatment for sleep problems after TBI exist. However, a recent manuscript outlined the potential benefit of treatment of sleep disorders in a series of 12 subjects.Catherine Wiseman-Hake........ Read more »

  • July 29, 2014
  • 10:37 AM
  • 68 views

STING-associated autoinflammatory disease

by Aurelie in The Immuno Blog

A study published in the New England Journal of Medicine describes an autoinflammatory syndrome associated with mutations in the gene encoding STING. Dubbed SAVI, for STING-associated vasculopathy with onset in infancy, the disease is characterized by systemic inflammation, severe cutaneous … Continue reading →... Read more »

Liu, Y., Jesus, A., Marrero, B., Yang, D., Ramsey, S., Sanchez, G., Tenbrock, K., Wittkowski, H., Jones, O., Kuehn, H.... (2014) Activated STING in a Vascular and Pulmonary Syndrome. New England Journal of Medicine, 2147483647. DOI: 10.1056/NEJMoa1312625  

  • July 29, 2014
  • 09:00 AM
  • 76 views

Finding the Missing Stories: The Prior Cemetery’s Unmarked Slave Graves

by Katy Meyers in Bones Don't Lie

One of the more common (though often frustrating) questions we get in archaeology is “Why are you doing historic archaeology? We already know what happened”. To some extent, for eras […]... Read more »

  • July 29, 2014
  • 07:35 AM
  • 107 views

Is Twitter Ruining Our Proper English?

by Katja Keuchenius in United Academics

“Hey al im on my way 2wrk but i totes 4got 2bring ur ipod sori il hav 2 bring it nxt tym ur workin. Hav a nice day xo”
Gives you the cramps? Maybe you should read this article.... Read more »

  • July 29, 2014
  • 07:30 AM
  • 94 views

Is homosexuality "natural"?

by Bill Sullivan in The 'Scope

In the beginning, there was no sex. That’s because in the beginning, there was no Barry White. A playful look at examples of homosexuality in nature.... Read more »

Van Houdenhove E, Gijs L, T'sjoen G, & Enzlin P. (2014) Asexuality: A Multidimensional Approach. Journal of sex research, 1-10. PMID: 24750031  

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