Prosthetics have come a long way in a relatively short amount of time. With the ongoing wars in the middle east the need for better prosthetics technologies has become more apparent, to this end we now have prosthetics that will allow a person to "feel", we even have motorized prosthetics that will help allow a more fluid walk, but while powered lower limb prosthetics hold promise for improving the mobility of amputees, errors in the technology may also cause some users to stumble or fall. Becau........ Read more »
Zhang, F., Liu, M., & Huang, H. (2014) Effects of Locomotion Mode Recognition Errors on Volitional Control of Powered Above-Knee Prostheses. IEEE Transactions on Neural Systems and Rehabilitation Engineering. DOI: 10.1109/TNSRE.2014.2327230
The EPA announced a plan to cut power plant emissions by 30% in about 15 years - get the details here!... Read more »
Fowlie, M., Goulder, L., Kotchen, M., Borenstein, S., Bushnell, J., Davis, L., Greenstone, M., Kolstad, C., Knittel, C., Stavins, R.... (2014) An economic perspective on the EPA's Clean Power Plan. Science, 346(6211), 815-816. DOI: 10.1126/science.1261349
Over the past several decades we have seen the advent of a number of new pharmaceutical drugs to treat depression, but major depressive disorder remains one of the most common mood disorders in the United States; over 15% of the population will suffer from major depressive disorder at some point in their lives. Despite extensive research into the etiology and treatment of depression, we haven't seen a mitigation of the impact depression has on our society. In fact, there have even been a lot of ........ Read more »
Canli, T. (2014) Reconceptualizing major depressive disorder as an infectious disease. Biology of Mood , 4(1), 10. DOI: 10.1186/2045-5380-4-10
Injecting a Placebo to Run Faster!... Read more »
Ross R, Gray CM, & Gill JM. (2014) The Effects of an Injected Placebo on Endurance Running Performance. Medicine and science in sports and exercise. PMID: 25412293
Even though most of my posts on MassGenomics concern human genetics and genomics, today I’d like to highlight a milestone in another species, one that many humans care fiercely about. This guy: Cat lovers, rejoice! This month in the Proceedings of the National Academy of Sciencs, Mike Montague, Wes Warren, and colleagues published the first complete […]... Read more »
Montague MJ, Li G, Gandolfi B, Khan R, Aken BL, Searle SM, Minx P, Hillier LW, Koboldt DC, Davis BW.... (2014) Comparative analysis of the domestic cat genome reveals genetic signatures underlying feline biology and domestication. Proceedings of the National Academy of Sciences of the United States of America. PMID: 25385592
Even kings and queens that have six legs and live underground aren’t immune to royal machinations. In one Asian termite species, queens choose to shut their mates out of the picture when it’s time to breed a successor. They simply clone themselves to make new queens. To keep the king’s genes away, the queen makes […]The post Termite Queen Clones Herself by Making Eggs Impervious to Sperm appeared first on Inkfish.... Read more »
Yashiro T, & Matsuura K. (2014) Termite queens close the sperm gates of eggs to switch from sexual to asexual reproduction. Proceedings of the National Academy of Sciences of the United States of America. PMID: 25404335
by Rita Handrich in The Jury Room
It’s a constantly moving target. Just over a year ago, we wrote about this on-going question and cited a Gallup Poll saying 65% of Black Americans have no preference when it comes to labels used to describe their racial or ethnic group. The authors of today’s research article would disagree. They say there are consequences […]
Should we say Black or African-American? Latino or Hispanic?
Everyday racism: A comparison of African American and Asian American Women
Are you........ Read more »
Hall, EV, Phillips, KW, & Townsend, SSM. (2014) A rose by any other name? The consequences of subtyping “African-Americans” from “Blacks”. . Journal of Experimental Social Psychology. . info:/
An eyebrow was raised upon reading the findings reported by Penelope Main and colleagues  concluding that: "it appears unlikely that genomic instability is a feature of the aetiology of autism." Based on results derived in part from "the cytokinesis-block micronucleus cytome (CBMN-cyt) assay"  looking at markers of DNA damage, authors reported very little to see in their small cohort of children with autism (n=35) compared with siblings (n=27) and asymptomatic controls (n=25) although with........ Read more »
Main PA, Thomas P, Angley MT, Young R, Esterman A, King CE, & Fenech MF. (2014) Lack of Evidence for Genomic Instability in Autistic Children as Measured by the Cytokinesis-Block Micronucleus Cytome Assay. Autism research : official journal of the International Society for Autism Research. PMID: 25371234
Researchers describe the use of traceable nanoparticles constructed to specifically target tumors. These drug loaded nano particles could function as ‘intelligent’ bullets, leaving body in 72 hours.... Read more »
Phillips E, Penate-Medina O, Zanzonico PB, Carvajal RD, Mohan P, Ye Y, Humm J, Gönen M, Kalaigian H, Schöder H.... (2014) Clinical translation of an ultrasmall inorganic optical-PET imaging nanoparticle probe. Science translational medicine, 6(260). PMID: 25355699
Statistical analyses of long-term monitoring data reveal an inverse relationship between the biomasses of zooplankton and plankton-eating fish, but only in the northern and central parts of the Barents Sea. In the southwestern Barents Sea, so such relationship is found.
... Read more »
Stige, L., Dalpadado, P., Orlova, E., Boulay, A., Durant, J., Ottersen, G., & Stenseth, N. (2014) Spatiotemporal statistical analyses reveal predator-driven zooplankton fluctuations in the Barents Sea. Progress in Oceanography, 243-253. DOI: 10.1016/j.pocean.2013.09.006
Mortality of pelagic eggs and larvae of marine fish is often assumed to be constant both in space and time due to lacking information. This may, however, be a gross oversimplification, as early life stages are likely to experience large variations in mortality both in time and space.
... Read more »
Langangen, �., Stige, L., Yaragina, N., Ottersen, G., Vikebø, F., & Stenseth, N. (2014) Spatial variations in mortality in pelagic early life stages of a marine fish (Gadus morhua). Progress in Oceanography, 96-107. DOI: 10.1016/j.pocean.2014.06.003
Understanding the drivers that determine the productivity of marine ecosystems is an important issue. Climate and exploitation interact in their effects, such that climate alterations may cause failure in a fishery management scheme while fisheries may disrupt the ability of a population to withstand, or adjust to, climate changes.
... Read more »
Durant, J., Hidalgo, M., Rouyer, T., Hjermann, D., Ciannelli, L., Eikeset, A., Yaragina, N., & Stenseth, N. (2013) Population growth across heterogeneous environments: effects of harvesting and age structure. Marine Ecology Progress Series, 277-287. DOI: 10.3354/meps10308
Ottersen, G., Stige, L., Durant, J., Chan, K., Rouyer, T., Drinkwater, K., & Stenseth, N. (2013) Temporal shifts in recruitment dynamics of North Atlantic fish stocks: effects of spawning stock and temperature. Marine Ecology Progress Series, 205-225. DOI: 10.3354/meps10249
Stige, L., Hunsicker, M., Bailey, K., Yaragina, N., & Hunt GL, J. (2013) Predicting fish recruitment from juvenile abundance and environmental indices. Marine Ecology Progress Series, 245-261. DOI: 10.3354/meps10246
Drug repurposing is predicated on the fact that many diseases are caused by the dysregulation of similar signaling pathways, or that drugs may affect several biological targets at once, meaning that a single drug may be able to treat multiple … Continue reading →... Read more »
Gramatica R, Di Matteo T, Giorgetti S, Barbiani M, Bevec D, & Aste T. (2014) Graph theory enables drug repurposing--how a mathematical model can drive the discovery of hidden mechanisms of action. PloS one, 9(1). PMID: 24416311
Increased training time in sports that require a forward lean posture can predispose young athletes to low back pain.... Read more »
van Hilst J, Hilgersom NF, Kuilman MC, Kuijer PP, & Frings-Dresen MH. (2014) Low back pain in young elite field hockey players, football players and speed skaters: Prevalence and risk factors. Journal of Back and Musculoskeletal Rehabilitation. PMID: 24968798
We all hate getting sick and the seasonal flu vaccine can help prevent a time of serious illness. Unfortunately the vaccine is usually an educated guess as to which strains of the flu are going to be most prevalent that year. Well now an international team of researchers has shown that it may be possible to improve the effectiveness of the seasonal flu vaccine by 'pre-empting' the evolution of the influenza virus.... Read more »
Fonville, J., Wilks, S., James, S., Fox, A., Ventresca, M., Aban, M., Xue, L., Jones, T., Le N. M. H., ., Pham Q. T., .... (2014) Antibody landscapes after influenza virus infection or vaccination. Science, 346(6212), 996-1000. DOI: 10.1126/science.1256427
These researchers’ abstract pretty much says it all (emphasis mine): Ethicists and guidelines have suggested that potential living kidney donors who withdraw from evaluation be offered an ‘alibi.’ We sought to determine what potential living kidney donors are told about their ability to opt out, alibi availability and postwithdrawal confidentiality. We reviewed 148 consent …
Continue reading »
The post Living Kidney Donor Consent Forms Don’t Make It Easy to Opt........ Read more »
Thiessen C, Kim YA, Formica R, Bia M, & Kulkarni S. (2014) Opting out: confidentiality and availability of an 'alibi' for potential living kidney donors in the USA. Journal of medical ethics. PMID: 25368413
Understanding the interaction between species is particularly actual in marine systems where ecosystem approach of management is desirable. This is particularly the case in high latitude systems such as the Barents Sea where climate change effect is supposed to be the strongest.
... Read more »
Durant, J., Skern-Mauritzen, M., Krasnov, Y., Nikolaeva, N., Lindstrøm, U., & Dolgov, A. (2014) Temporal Dynamics of Top Predators Interactions in the Barents Sea. PLoS ONE, 9(11). DOI: 10.1371/journal.pone.0110933
Short supplies of adequate nesting sites and food resources are often associated in discussions of the ultimate factors controlling seabird population size, distribution and breeding success. Shift of prey distribution may affect the interaction between seabirds breeding at the same site.
... Read more »
Durant, J., Krasnov, Y., Nikolaeva, N., & Stenseth, N. (2011) Within and between species competition in a seabird community: statistical exploration and modeling of time-series data. Oecologia, 169(3), 685-694. DOI: 10.1007/s00442-011-2226-3
What is the intestinal barrier? What is intestinal permeability? What factors affect the permeability of the intestinal barrier? How do you measure intestinal permeability? How might [altered] intestinal permeability link to health, well-being and various clinical diagnoses?The new triad @ Bischoff SC et al. 2014These are some of the questions tackled by the excellent open-access review by Stephan Bischoff and colleagues  which I would like to draw your attention to i........ Read more »
Bischoff, S., Barbara, G., Buurman, W., Ockhuizen, T., Schulzke, J., Serino, M., Tilg, H., Watson, A., & Wells, J. (2014) Intestinal permeability - a new target for disease prevention and therapy. BMC Gastroenterology, 14(1), 189. DOI: 10.1186/s12876-014-0189-7
The "Natwest 3" jailedfor wire fraud in 2008.Picture a banker tossing a coin ten times. She knows the more tails she gets, the more money she wins (up to $200), so long as she gets more tails than a rival playing the same game. She performs her coin tossing in private and reports her number of tails. Do you think she'll be honest?When a team of researchers surveyed the general population about the likely dishonesty of bankers and other groups in this scenario, they found the bankers had the wors........ Read more »
Alain Cohn, Ernst Fehr, & Michel Marechal. (2014) Business culture and dishonesty in the banking industry. Nature . info:/
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