Where is the septum?
The term septum, when used in reference to the brain (it is a common anatomical term used to refer to a partition), indicates a subcortical structure in the forebrain that is found near the midline of the brain. The septum in humans can be separated into two structures: the septum pellucidum and septum verum. Each of these is sometimes........ Read more »
Sheehan, T., Chambers, R., & Russell, D. (2004) Regulation of affect by the lateral septum: implications for neuropsychiatry. Brain Research Reviews, 46(1), 71-117. DOI: 10.1016/j.brainresrev.2004.04.009
"Prescription drug use and polypharmacy rates among adults with ASD [autism spectrum disorder] are substantially higher than those in an age-, sex-, and race-matched cohort of adults without ASD."That sentence taken from the paper by Rini Vohra and colleagues  (open-access available here) is probably not likely to win any 'novel findings of the year' awards given the already quite voluminous data published on the medication use and autism (see here for example). What gives the ........ Read more »
Vohra R, Madhavan S, Sambamoorthi U, StPeter C, Poe S, Dwibedi N, & Ajmera M. (2016) Prescription Drug Use and Polypharmacy Among Medicaid-Enrolled Adults with Autism: A Retrospective Cross-Sectional Analysis. Drugs - real world outcomes. PMID: 27873285
by Livia Gerber in Language on the Move
A 2015 article in the New York Post argued that mobile dating apps, such as Tinder and its many clones,...... Read more »
Hobbs, M., Owen, S., & Gerber, L. (2016) Liquid love? Dating apps, sex, relationships and the digital transformation of intimacy. Journal of Sociology. DOI: 10.1177/1440783316662718
Research considers that the diagnosis of congenital malformation may affect maternal mental health during pregnancy. Symptoms of anxiety and depression can occur from the first quarter, impacting also on the family, especially if the communication of the diagnosis is not careful. They conclude that the coping face to this situation and the impact of bad news can be minimized by the pregnant woman's support network. … Read More →... Read more »
CUNHA, A., PEREIRA JUNIOR, J., CALDEIRA, C., & CARNEIRO, V. (2016) Diagnóstico de malformações congênitas: impactos sobre a saúde mental de gestantes. Estudos de Psicologia (Campinas), 33(4), 601-611. DOI: 10.1590/1982-02752016000400004
A recently-published study has now resolved the mystery of the bison bones, with the help of some Ice Age cave artists. It turns out that there once existed, during the Ice Age, a hybrid between the now-extinct aurochs (the beast from which we domesticated the cow) and the equally-extinct steppe bison (basically, the Asian version of the American bison).... Read more »
Soubrier, J., Gower, G., Chen, K., & et al. (2016) Early cave art and ancient DNA record the origin of European bison. Nature Communications, 13158. DOI: 10.1038/ncomms13158
"A total of 22 original papers that examined the association between folic acid supplementation in human pregnancy and neurodevelopment/autism were identified after the screening, with 15 studies showing a beneficial effect of folic acid supplementation on neurodevelopment/autism, 6 studies showed no statistically significant difference, while one study showed a harmful effect in > 5 mg folic acid supplementation/day during pregnancy."That rather long quote taken from the paper published by Y........ Read more »
Gao Y, Sheng C, Xie RH, Sun W, Asztalos E, Moddemann D, Zwaigenbaum L, Walker M, & Wen SW. (2016) New Perspective on Impact of Folic Acid Supplementation during Pregnancy on Neurodevelopment/Autism in the Offspring Children - A Systematic Review. PloS one, 11(11). PMID: 27875541
New research looks at the factors that influence how we feel after euthanizing a pet.The loss of a pet is a difficult process. People’s feelings of grief may be the same as for losing a human family member. New research investigates some of the factors that may affect people’s grief and sorrow after euthanizing a dog or cat.The study, by Sandra Barnard-Nguyen (University of Sydney) et al, is one of the first to use a survey designed specifically to measure people’s responses to loss o........ Read more »
Barnard-Nguyen, S., Breit, M., Anderson, K., & Nielsen, J. (2016) Pet Loss and Grief: Identifying At-risk Pet Owners during the Euthanasia Process. Anthrozoös, 29(3), 421-430. DOI: 10.1080/08927936.2016.1181362
MicroRNAs (miRNAs) are non-coding RNAs, roughly 22 nucleotides in size that are central and negative regulators of gene expression. They exert their functions through base-pairing with the 3’UTR of mRNAs and block expression at the transcriptional and post-transcriptional levels, depending on the perfect or imperfect match in sequences between miRNAs and their target genes. miRNAs are central nodes in a variety of biological processes like cell proliferation, apoptosis, migration and dif........ Read more »
Parodi F, Carosio R, Ragusa M, Di Pietro C, Maugeri M, Barbagallo D, Sallustio F, Allemanni G, Pistillo MP, Casciano I.... (2016) Epigenetic dysregulation in neuroblastoma: A tale of miRNAs and DNA methylation. Biochimica et biophysica acta, 1859(12), 1502-1514. PMID: 27751904
A Blanket high dose vitamin D supplement plan results in elevated levels of vitamin D metabolites after the supplementation is completed. This could result in lower than normal levels of vitamin D, which is the opposite effect of the intended supplementation.... Read more »
Owens DJ, Tang JC, Bradley WJ, Sparks SA, Fraser WD, Morton JP, & Close GL. (2016) Efficacy of High Dose Vitamin D Supplements for Elite Athletes. Medicine and science in sports and exercise. PMID: 27741217
Does non-ionizing radiation pose a health risk? Everyone knows that ionizing radiation, like gamma rays, can cause cancer by damaging DNA. But the scientific consensus is that there is no such risk from non-ionizing radiation such as radiowaves or Wi-Fi.
Yet according to a remarkable new paper from Magda Havas, the risk is real: it's called When theory and observation collide: Can non-ionizing radiation cause cancer?
There are a few remarkable things about this paper but chief among th... Read more »
Havas, M. (2016) When theory and observation collide: Can non-ionizing radiation cause cancer?. Environmental Pollution. DOI: 10.1016/j.envpol.2016.10.018
It would be great if, before starting a therapy, it was possible to test small doses of several drugs, at the same time, in a patient and compare their effects on the tumor, so to identify the one that works best.
The study of Yaari and colleagues from the Israel Institute of Technology in Haifa, published in Nature Communication, opens a way to this achievement.... Read more »
Yaari, Z., da Silva, D., Zinger, A., Goldman, E., Kajal, A., Tshuva, R., Barak, E., Dahan, N., Hershkovitz, D., Goldfeder, M.... (2016) Theranostic barcoded nanoparticles for personalized cancer medicine. Nature Communications, 13325. DOI: 10.1038/ncomms13325
Insomnia of sufficient severity to meet clinical significance is estimated to affect up to 20% of the general population.This makes insomnia an important public health challenge.Effective, inexpensive and accessible programs to treat insomnia are needed.One recent controlled clinical trial supports the promise of an online intervention that incorporates key elements of cognitive behavioral therapy (CBT).Lee Ritterband and colleagues at the University of Virginia recently published a controlled c........ Read more »
Ritterband LM, Thorndike FP, Ingersoll KS, Lord HR, Gonder-Frederick L, Frederick C, Quigg MS, Cohn WF, & Morin CM. (2016) Effect of a Web-Based Cognitive Behavior Therapy for Insomnia Intervention With 1-Year Follow-up: A Randomized Clinical Trial. JAMA psychiatry. PMID: 27902836
The vast majority of professors will gladly meet a prospective graduate student and discuss research opportunities as well as long-term career options, especially if the student requesting the meeting clarifies the goal of the meeting. However, there are cases when students wait in vain for a response. Is it because their email never reached the professor because it got lost in the internet ether or a spam folder? Was the professor simply too busy to respond? A research study headed by Katherine........ Read more »
Milkman KL, Akinola M, & Chugh D. (2015) What happens before? A field experiment exploring how pay and representation differentially shape bias on the pathway into organizations. The Journal of applied psychology, 100(6), 1678-712. PMID: 25867167
Occasionally the Sun ejects a pair of magnetized plasma clouds, called coronal mass ejections (CMEs), roughly into the same propagation direction in closely timed sequence. If the second CME is faster than the first one, the CMEs could either just slip through each other or they could collide and interact, [...]... Read more »
Mäkelä, P., Gopalswamy, N., Reiner, M., Akiyama, S., & Krupar, V. (2016) SOURCE REGIONS OF THE TYPE II RADIO BURST OBSERVED DURING A CME–CME INTERACTION ON 2013 MAY 22. The Astrophysical Journal, 827(2), 141. DOI: 10.3847/0004-637X/827/2/141
Increased body fat and physical inactivity may be modifiable risk factors for osteoporosis and sarcopenia. ... Read more »
Lee I, Cho J, Jin Y, Ha C, Kim T, & Kang H. (2016) Body Fat and Physical Activity Modulate the Association Between Sarcopenia and Osteoporosis in Elderly Korean Women. Journal of sports science , 15(3), 477-482. PMID: 27803626
Identify everyone born in Denmark between 1985-2002. Identify those treated "in the primary care setting" for an infection. Identify those diagnosed with schizophrenia and affective disorders. Look-see whether there is an overlap between infection or treated infection and schizophrenia / affective disorders. Report results.That's basically the study published by Köhler and colleagues  (a name that has appeared on this blog before) who concluded that: "Infections treated with anti-infect........ Read more »
Köhler O, Petersen L, Mors O, Mortensen PB, Yolken RH, Gasse C, & Benros ME. (2016) Infections and exposure to anti-infective agents and the risk of severe mental disorders: a nationwide study. Acta psychiatrica Scandinavica. PMID: 27870529
Individual differences may be seen in baseline SCAT3 data between sex, history of concussion, and history of comorbidities. Therefore, using the patient’s personal medical history may add value to the SCAT3 sideline screening.... Read more »
Snedden TR, Brooks MA, Hetzel S, & McGuine T. (2016) Normative Values of the Sport Concussion Assessment Tool 3 (SCAT3) in High School Athletes. Clinical journal of sport medicine. PMID: 27606952
It was inevitable ("it is your destiny") that I would formulate a post about the paper published by Khaled Saad and colleagues  reporting results based on "a double-blinded, randomized clinical trial (RCT)" looking at the potential usefulness of a vitamin D supplement on "the core symptoms of autism in children." Inevitable because the peer-reviewed research literature looking at the sunshine vitamin/hormone in relation to autism is getting rather voluminous (see here and see here f........ Read more »
Saad K, Abdel-Rahman AA, Elserogy YM, Al-Atram AA, El-Houfey AA, Othman HA, Bjørklund G, Jia F, Urbina MA, Abo-Elela MG.... (2016) Randomized controlled trial of vitamin D supplementation in children with autism spectrum disorder. Journal of child psychology and psychiatry, and allied disciplines. PMID: 27868194
Most neuroscientists will tell you that long-term memories are stored in the brain in the form of synapses, the connections between neurons. On this view, memory formation occurs when synaptic connections are strengthened, or entirely new synapses are formed.
However, in a new piece in Frontiers in Systems Neuroscience, Austrian researcher Patrick C. Trettenbrein critiques the synapse-memory theory: The Demise of the Synapse As the Locus of Memory.
Trettenbrein acknowledges that "t... Read more »
Trettenbrein, P. (2016) The Demise of the Synapse As the Locus of Memory: A Looming Paradigm Shift?. Frontiers in Systems Neuroscience. DOI: 10.3389/fnsys.2016.00088
Fig. 4 (Wexler, 2016). Lindstrom's Electro-Medical Apparatus (ca. 1895), courtesy of the Bakken.
Think the do-it-yourself transcranial direct current stimulation movement (DIY tDCS) is a technologically savvy and hip creation of 21st century neural engineering? MIT graduate student Anna Wexler has an excellent and fun review of late 19th and early 20th century electrical stimulation
... Read more »
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