by sciencebase in Sciencebase Science Blog
I recently saw a research paper discussing the lack of tools for designers hoping to make their products greener, more environmentally benign, sustainable even. The paper focused more on the likes of coming up with a green espresso machine and offered a five-step scheme for getting the green credentials booked into a the design and [...]Five-step plan for green design is a post from: Sciencebase Science Blog
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Dominique Millet, Nicolas Tchertchian, & Daniel Brissaud. (2009) How to identify the most promising areas of environmental improvement at the early stages of the design process?. Int. J. Design Engineering, 2(3), 299-319. info:/
by DrugMonkey in DrugMonkey
There is an interesting paper that I just ran across which will possibly please a certain segment of my audience. You see, it provides a bit of a test of the hypothesis frequently bandied by my commenters that anti-drug messages backfire. That if you tell adolescents all sorts of bad things are going to happen to them if they try an illicit drug once, and it doesn't happen, somehow you are actually encouraging them to try the drug again. This general area is an occasional interest of mine and yo........ Read more »
Skenderian, J., Siegel, J., Crano, W., Alvaro, E., & Lac, A. (2008) Expectancy change and adolescents' intentions to use marijuana. Psychology of Addictive Behaviors, 22(4), 563-569. DOI: 10.1037/a0013020
by Dr Shock in Dr Shock MD PhD
In short, a recent article proposed to do deep brain stimulation for schizophenia. Schizophrenia has positive-, negative- and cognitive symptoms (see the figure above). The authors propose the DBS for positive symptoms. Their approach is based on current models of the neurocircuitry of psychosis .
They hypothesize:
that chronic, high frequency electrical stimulation (HFS) of [...]
Related posts:New Innovations in Deep Brain Stimulation Surgery A great step forward, patients don’t hav........ Read more »
Mikell, C., McKhann, G., Segal, S., McGovern, R., Wallenstein, M., & Moore, H. (2009) The Hippocampus and Nucleus Accumbens as Potential Therapeutic Targets for Neurosurgical Intervention in Schizophrenia. Stereotactic and Functional Neurosurgery, 87(4), 256-265. DOI: 10.1159/000225979
Bakay, R. (2009) Deep Brain Stimulation for Schizophrenia. Stereotactic and Functional Neurosurgery, 87(4), 266-266. DOI: 10.1159/000225980
by Paul Spraycar in Beyond Climate Change
A recent paper in Ecology Letters, “Understanding relationships among multiple ecosystem services,” addresses the relationship among multiple ecosystem services at a single site, addressing in particular one consequence of maximizing one ecosystem service: other services often decline substantially.
Despite growing interest in ecosystem services, the authors contend that much of the research literature is limited by only considering a single ecosystem service, or at most two service........ Read more »
Bennett, E., Peterson, G., & Gordon, L. (2009) Understanding relationships among multiple ecosystem services. Ecology Letters, 12(12), 1394-1404. DOI: 10.1111/j.1461-0248.2009.01387.x
by Olexandr Isayev in olexandrisayev.com
The Brookhaven team, has been refining techniques to use strands of artificial DNA as a highly specific kind of Velcro or glue to link up nanoparticles. Such DNA-based self-assembly holds promise for the rational design of a range of new materials for applications in molecular separation, electronics, energy conversion, and other fields. But none of these structures has had the ability to change in a programmable manner in response to molecular stimuli — until now. “Now we’re u........ Read more »
Maye, M., Kumara, M., Nykypanchuk, D., Sherman, W., & Gang, O. (2009) Switching binary states of nanoparticle superlattices and dimer clusters by DNA strands. Nature Nanotechnology. DOI: 10.1038/nnano.2009.378
by Lorimer Moseley in BodyInMind
From a biological perspective, I find CRPS very perplexing. So do many other people—the community of scientists that are pursuing better treatments, through a better understanding of the basic mechanisms, or by developing better animal models of CRPS, or by undertaking clinical investigations and clinical trials, stretches across many countries and many scientific and clinical disciplines. With all of those supposedly clever people working on it, one might expect that by now [........ Read more »
Lorimer Moseley. (2009) The Brain in CRPS-More Barriers or New Opportunities. Bodyinmind.com.au. info:/
One of Charles R. Knight's wonderful paintings of woolly mammoths walking through the snow of ancient Europe. On display at the Field Museum in Chicago.
When did the last woolly mammoths die?
There is no easy answer to the question. In its heyday the woolly mammoth (Mammuthus primigenius) was distributed across much of the northern hemisphere, from southern Spain to the eastern United States, and the entire species did not simply lay down and die at one particular moment. Some populations........ Read more »
Haile, J., Froese, D., MacPhee, R., Roberts, R., Arnold, L., Reyes, A., Rasmussen, M., Nielsen, R., Brook, B., Robinson, S.... (2009) Ancient DNA reveals late survival of mammoth and horse in interior Alaska. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.0912510106
by Journal Watch Online in Journal Watch Online
Fisheries with catch-share programs are more stable
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Essington, T. (2009) Ecological indicators display reduced variation in North American catch share fisheries. Proceedings of the National Academy of Sciences. info:/10.1073/pnas.0907252107
by Michael Long in Phased
Mark Welford and Brian Bossak (Georgia Southern University) shed doubt on the long-held conclusion that the Black Death was caused by bubonic and pneumonic plague. This news feature was written on December 22, 2009.... Read more »
Welford, M. R., & Bossak, B. H. (2009) Validation of Inverse Seasonal Peak Mortality in Medieval Plagues, Including the Black Death, in Comparison to Modern Yersinia pestis-Variant Diseases. PLoS ONE, 4(12). DOI: 10.1371/journal.pone.0008401
by Christie Wilcox in Nutrition Wonderland
In the past year or two, certified organic sales have jumped around 30% to about $52 billion (2008 dollars) worldwide despite the fact that organic foods cost up to three times as much as those produced by conventional methods. More and more, people are shelling out their hard-earned cash for Certified Organic. Imagine, people say: you can improve your nutrition while helping save the planet from the evils of conventional agriculture – a complete win-win. And who wouldn’t buy organic........ Read more »
Gold, L., Slone, T., Stern, B., Manley, N., & Ames, B. (1992) Rodent carcinogens: setting priorities. Science, 258(5080), 261-265. DOI: 10.1126/science.1411524
Caboni, P., Sherer, T., Zhang, N., Taylor, G., Na, H., Greenamyre, J., & Casida, J. (2004) Rotenone, Deguelin, Their Metabolites, and the Rat Model of Parkinson's Disease. Chemical Research in Toxicology, 17(11), 1540-1548. DOI: 10.1021/tx049867r
Mukherjee A, Speh D, Dyck E, & Diez-Gonzalez F. (2004) Preharvest evaluation of coliforms, Escherichia coli, Salmonella, and Escherichia coli O157:H7 in organic and conventional produce grown by Minnesota farmers. Journal of food protection, 67(5), 894-900. PMID: 15151224
Fillion, L., & Arazi, S. (2002) Does organic food taste better? A claim substantiation approach. Nutrition , 32(4), 153-157. DOI: 10.1108/00346650210436262
by Journal Watch Online in Journal Watch Online
Acidified oceans will transmit more sound
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Ilyina, T., Zeebe, R., & Brewer, P. (2009) Future ocean increasingly transparent to low-frequency sound owing to carbon dioxide emissions. Nature Geoscience, 3(1), 18-22. DOI: 10.1038/NGEO719
by Jason Snyder in Functional Neurogenesis
A review of the Cell paper by Kitamura, Inokuchi and colleagues on the role of adult-born neurons in systems consolidation of memory.... Read more »
Kitamura T, Saitoh Y, Takashima N, Murayama A, Niibori Y, Ageta H, Sekiguchi M, Sugiyama H, & Inokuchi K. (2009) Adult neurogenesis modulates the hippocampus-dependent period of associative fear memory. Cell, 139(4), 814-27. PMID: 19914173
by Vincent Racaniello in virology blog
Millions of New Yorkers were immunized against smallpox within a few weeks in April 1947. The stimulus for this mass immunization was the importation of smallpox by a businessman who had acquired the disease during his travels. While we are in the middle of a massive influenza immunization campaign, it is useful to review the [...]... Read more »
Sepkowitz KA. (2004) The 1947 smallpox vaccination campaign in New York City, revisited. Emerging infectious diseases, 10(5), 960-1. PMID: 15216846
by Nestor Lopez-Duran PhD in Child-Psych
By now most people interested in autism have read the CDC report, or at least read the news, regarding the new estimated prevalence rates of autism in the United States. Today I finally was able to read the full original report and have some brief general thoughts.
The report is based on the findings by the [...]... Read more »
Kogan, M., Blumberg, S., Schieve, L., Boyle, C., Perrin, J., Ghandour, R., Singh, G., Strickland, B., Trevathan, E., & van Dyck, P. (2009) Prevalence of Parent-Reported Diagnosis of Autism Spectrum Disorder Among Children in the US, 2007. PEDIATRICS, 124(5), 1395-1403. DOI: 10.1542/peds.2009-1522
by Michael Long in Phased
Carmen Lisowski and James Hutchison (University of Oregon) have developed a color-based assay for a versatile, widely-utilized class of ions that are increasingly becoming a pollution concern. This news feature was written on December 22, 2009.... Read more »
Lisowski CE, & Hutchison JE. (2009) Malonamide-functionalized gold nanoparticles for selective, colorimetric sensing of trivalent lanthanide ions. Analytical chemistry, 81(24), 10246-53. PMID: 19904966
by Cancer Research UK in Cancer Research UK - Science Update
We’ll be taking a break from blogging over the festive period, but we’ll be back in January with more top science, myth-busting and podcasts. In the meantime, here’s a quick run-down of some of the biggest stories that we’ve covered on the blog this year.
Going all the way back to January, our researchers discovered how [...]... Read more »
Chisholm, E., Vassaux, G., Martin-Duque, P., Chevre, R., Lambert, O., Pitard, B., Merron, A., Weeks, M., Burnet, J., Peerlinck, I.... (2009) Cancer-Specific Transgene Expression Mediated by Systemic Injection of Nanoparticles. Cancer Research, 69(6), 2655-2662. DOI: 10.1158/0008-5472.CAN-08-2657
Lubbe, S., Webb, E., Chandler, I., & Houlston, R. (2009) Implications of Familial Colorectal Cancer Risk Profiles and Microsatellite Instability Status. Journal of Clinical Oncology. DOI: 10.1200/JCO.2008.20.3364
Attard, G., Reid, A., A'Hern, R., Parker, C., Oommen, N., Folkerd, E., Messiou, C., Molife, L., Maier, G., Thompson, E.... (2009) Selective Inhibition of CYP17 With Abiraterone Acetate Is Highly Active in the Treatment of Castration-Resistant Prostate Cancer. Journal of Clinical Oncology. DOI: 10.1200/JCO.2008.20.0642
Cawood, R., Chen, H., Carroll, F., Bazan-Peregrino, M., van Rooijen, N., & Seymour, L. (2009) Use of Tissue-Specific MicroRNA to Control Pathology of Wild-Type Adenovirus without Attenuation of Its Ability to Kill Cancer Cells. PLoS Pathogens, 5(5). DOI: 10.1371/journal.ppat.1000440
Gupta, P., Onder, T., Jiang, G., Tao, K., Kuperwasser, C., Weinberg, R., & Lander, E. (2009) Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening. Cell. DOI: 10.1016/j.cell.2009.06.034
Eeles, R., Kote-Jarai, Z., Al Olama, A., Giles, G., Guy, M., Severi, G., Muir, K., Hopper, J., Henderson, B., Haiman, C.... (2009) Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. Nature Genetics. DOI: 10.1038/ng.450
Al Olama, A., Kote-Jarai, Z., Giles, G., Guy, M., Morrison, J., Severi, G., Leongamornlert, D., Tymrakiewicz, M., Jhavar, S., Saunders, E.... (2009) Multiple loci on 8q24 associated with prostate cancer susceptibility. Nature Genetics. DOI: 10.1038/ng.452
Pleasance, E., Cheetham, R., Stephens, P., McBride, D., Humphray, S., Greenman, C., Varela, I., Lin, M., Ordóñez, G., Bignell, G.... (2009) A comprehensive catalogue of somatic mutations from a human cancer genome. Nature. DOI: 10.1038/nature08658
Pleasance, E., Stephens, P., O’Meara, S., McBride, D., Meynert, A., Jones, D., Lin, M., Beare, D., Lau, K., Greenman, C.... (2009) A small-cell lung cancer genome with complex signatures of tobacco exposure. Nature. DOI: 10.1038/nature08629
by Joe Dunckley in Cotch
Since sequencing the human genome, the Sanger Institute in the UK and the US National Human Genome Research Institute have turned their sights -- and their vast sequencing capacities -- to cancer. Cancers can be thought of as genomic diseases, caused by somatic mutations, and progressing by the accumulation of further mutations. Last week, Nature published online the papers describing two new cancer genomes, bringing the total number of human cancer genome sequences published to five...... Read more »
Pleasance, E., Stephens, P., O’Meara, S., McBride, D., Meynert, A., Jones, D., Lin, M., Beare, D., Lau, K., Greenman, C.... (2009) A small-cell lung cancer genome with complex signatures of tobacco exposure. Nature. DOI: 10.1038/nature08629
by Michael Long in Phased
Qiang Xu (AIST, Japan) and coworkers have achieved complete chemical conversion of hydrous hydrazine to nitrogen and hydrogen at room temperature, with a metal nanoparticle catalyst. This news feature was written on December 22, 2009.... Read more »
Singh SK, & Xu Q. (2009) Complete conversion of hydrous hydrazine to hydrogen at room temperature for chemical hydrogen storage. Journal of the American Chemical Society, 131(50), 18032-3. PMID: 19928987
by Rob Goldstein in Conservation Maven
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Ashe, E., Noren, D., & Williams, R. (2009) Animal behaviour and marine protected areas: incorporating behavioural data into the selection of marine protected areas for an endangered killer whale population. Animal Conservation. DOI: 10.1111/j.1469-1795.2009.00321.x
by Psi Wavefunction in Skeptic Wonder
Of course, no one noticed any delays in the posting of the Sunday Protist, because that never happened. Actually, I've been rather frazzled by this little fun activity that happens around this time of the year called 'finals', and thus had to desperately avoid any material I may find myself actually interested in, lest it hijacks my attention for too long. Also, I'll be mostly internetless starting tomorrow, and thus unable to blog. Coming back on 03 January. May or may not schedule a post, depe........ Read more »
Agatha S. (2004) A cladistic approach for the classification of oligotrichid ciliates (Ciliophora: Spirotricha). Acta Protozoologica , 43(3), 201-217. info:/
AGATHA, S. (2004) Evolution of ciliary patterns in the Oligotrichida (Ciliophora, Spirotricha) and its taxonomic implications. Zoology, 107(2), 153-168. DOI: 10.1016/j.zool.2004.02.003
AGATHA, S., STRUDER-KYPKE, M., & BERAN, A. (2004) Morphologic and Genetic Variability in the Marine Planktonic Ciliate Laboea strobila Lohmann, 1908 (Ciliophora, Oligotrichia), with Notes on its Ontogenesis. The Journal of Eukaryotic Microbiology, 51(3), 267-281. DOI: 10.1111/j.1550-7408.2004.tb00567.x
Gao, S., Gong, J., Lynn, D., Lin, X., & Song, W. (2009) An updated phylogeny of oligotrich and choreotrich ciliates (Protozoa, Ciliophora, Spirotrichea) with representative taxa collected from Chinese coastal waters. Systematics and Biodiversity, 7(02), 235. DOI: 10.1017/S1477200009002989
MODEO, L., PETRONI, G., ROSATI, G., & MONTAGNES, D. (2003) A Multidisciplinary Approach to Describe Protists: Redescriptions of Novistrombidium testaceum Anigstein 1914 and Strombidium inclinatum Montagnes, Taylor, and Lynn 1990 (Ciliophora, Oligotrichia). The Journal of Eukaryotic Microbiology, 50(3), 175-189. DOI: 10.1111/j.1550-7408.2003.tb00114.x
Skovgaard, A., & Legrand, C. (2005) Observation of live specimens of Pseudotontonia cornuta (Ciliophora: Oligotrichida) reveals new distinctive characters. Journal of the Marine Biological Association of the United Kingdom, 85(4), 783-786. DOI: 10.1017/S0025315405011707
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