Post List

  • July 6, 2011
  • 06:35 AM

Cultural or universal

by David Winter in Careers - in Theory

In The East and West of Careers Guidance, my colleague Saiyada talked about the Jiva project promoting career development counselling in India. A recent paper by G. Arulmani (2011) expands on some of the cultural concepts that underlie this approach to careers work. I have my reservations about the research presented in the paper which [...]... Read more »

Arulmani, G. (2011) Striking the right note: the cultural preparedness approach to developing resonant career guidance programmes. International Journal for Educational and Vocational Guidance, 11(2), 79-93. info:/10.1007/s10775-011-9199-y

  • July 6, 2011
  • 05:18 AM

Single-molecule investigations of the stringent response machinery in living bacterial cells

by Vasili Hauryliuk in stringent response

Wikipedia: "reductionism, an approach to understanding the nature of complex things by reducing them to the interactions of their parts, or to simpler or more fundamental things". This approach was very successful in unrevealing the basic mechanisms of biological systems. Modern biochemistry is reductionism in its pure form: we purify individual components, mix them together in a test tube and make this in vitro system jump through the hoops and ........ Read more »

Potrykus K, & Cashel M. (2008) (p)ppGpp: still magical?. Annual review of microbiology, 35-51. PMID: 18454629  

Gallant J, Palmer L, & Pao CC. (1977) Anomalous synthesis of ppGpp in growing cells. Cell, 11(1), 181-5. PMID: 326415  

Brian P. English, Vasili Hauryliuk, Arash Sanamrad, Stoyan Tankov, Nynke H. Dekker, and Johan Elf. (2011) Single-molecule investigations of the stringent response machinery in living bacterial cells. Proceedings of the National Academy of Sciences of the United States of America. info:/

  • July 6, 2011
  • 05:07 AM

Tightening the interval of the expected

by Razib Khan in Gene Expression

The Pith: The rarer the genetic variant, the more likely that variant is to be specific to a distinct population. Including information about the distribution of these genetic variants missed in current techniques can increase greatly the precision of statistical inferences.
A few days ago I mentioned in passing an article in The New York Times which reported on results from a paper which illustrated how starkly differentiated populations might be on rare alleles. By this, I mean that some genet........ Read more »

Simon Gravel, Brenna M. Henn, Ryan N. Gutenkunst, Amit R. Indap, Gabor T. Marth, Andrew G. Clark, Fuli Yu, Richard A. Gibbs, The 1000 Genomes Project, & and Carlos D. Bustamante. (2011) Demographic history and rare allele sharing among human populations. PNAS. info:/10.1073/pnas.1019276108

  • July 6, 2011
  • 04:50 AM

There’s no conspiracy – sometimes it just doesn’t work

by Cancer Research UK in Cancer Research UK - Science Update

At Cancer Research UK, we’re often asked about alleged “miracle cures” for cancer, usually based on claims made on the internet. There’s an impressive list of these collected on the Quackwatch website (here and here), ranging from the slightly wacky to the downright dangerous. In virtually all cases, when researchers have rigorously tested these treatments, [...]... Read more »

Bashford EF. (1911) CANCER, CREDULITY, AND QUACKERY. British medical journal, 1(2630), 1221-30. PMID: 20765638  

Imperial Cancer Research Fund. (1907) IMPERIAL CANCER RESEARCH FUND. British medical journal, 2(2427), 26-9. PMID: 20763346  

No authors listed. (1906) THE COMPOSITION OF SOME CANCER "REMEDIES.". British medical journal, 1(2369), 1238. PMID: 20762692  

  • July 6, 2011
  • 03:29 AM

Autism Isn't Very Genetic...Or Is It?

by Neuroskeptic in Neuroskeptic

The environment is more important than genetics in setting the risk for autism, according to a new study that's got the media in a tizzy.The paper, which is free, is here: Genetic Heritability and Shared Environmental Factors Among Twin Pairs With AutismIt's a twin study, and like all such research, it aims to estimate heritability, the proportion of the variability in autism risk caused by straightforward genetic effects. A heritability of 0% means no genetics and 100% means purely genetic. No........ Read more »

Joachim Hallmayer, et al. (2011) Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism. Archives of General Psychiatry. info:/

  • July 6, 2011
  • 03:00 AM

Is exportation of hazardous waste the future solution, in the face of unsustainable methods?

by SAGE Insight in SAGE Insight

Review article: Persistent organic pollutants and landfills – a review of past experiences and future challenges From Waste Management & Research The landfilling and dumping of persistent organic pollutants (POPs) and other persistent hazardous compounds can have significant adverse environmental consequences. POPs will persist in landfills for many decades and possibly centuries. The build up [...]... Read more »

  • July 6, 2011
  • 02:52 AM

Trading AIDS for aging?

by Nerdy One in Try Nerdy

Acquired immunodeficiency syndrome (AIDS) is an immune disease caused by infection with human immunodeficiency virus (HIV) and has been responsible for more than 2 million deaths worldwide each year since 2003. The HIV virus attacks and kills immune cells until their numbers are so low that a person is classified as having AIDS, with essentially no remaining cell-based immunity against opportunistic infections that could normally be fought off by the body but are now potentially fatal to the aff........ Read more »

  • July 6, 2011
  • 01:52 AM

REPOST: Oral Contraceptives and Weight Gain, Myths and Truths and Anecdotes

by Scicurious in Neurotic Physiology

And lions and tigers and bears! Sci is reposting this one in particular because I keep seeing it come up. Again and again I read articles on how combined hormonal contraceptives don't cause weight gain. And again and again I see women posting everywhere on the internet not to trust those dang scientists! I gained [...]... Read more »

Gallo MF, Lopez LM, Grimes DA, Schulz KF, & Helmerhorst FM. (2008) Combination contraceptives: effects on weight. Cochrane database of systematic reviews (Online). PMID: 18843652  

  • July 5, 2011
  • 07:42 PM

The Undiagnosed Epidemic of Incarceration

by Dirk Hanson in Addiction Inbox

Prison once again a place for addicts and the mentally ill.

Readers may remember the dark day of January 1, 2008, when the U.S. set an all-time record: One out of every 100 adults was behind bars. That’s more than 2.3 million people. That’s 25% of all the prisoners in the world—and the world includes some very nasty nations. What gives?

You know the answer: drug crimes. Can it really be a coincidence that over the past 40 years, ever since President Richard Nixon first declared war on ........ Read more »

Rich JD, Wakeman SE, & Dickman SL. (2011) Medicine and the epidemic of incarceration in the United States. The New England journal of medicine, 364(22), 2081-3. PMID: 21631319  

  • July 5, 2011
  • 04:44 PM

Hexagonal orientation maps in V1

by Patrick Mineault in xcorr

Interesting paper from Se-Bum Paik and Dario Ringach in this month’s issue of Nature Neuroscience on the origins of the orientation map in V1. Dr. Ringach has been developing a model of V1 orientation selectivity for a number of years now, the statistical connectivity hypothesis, based on the idea that the retinotopic map in V1 [...]... Read more »

  • July 5, 2011
  • 04:35 PM

Amber Snail Puzzle

by Africa Gomez in BugBlog

While removing an old pot containing a lot of grass and a dead Agapanthus, next to a rainwater filled pot, I stumbled upon this little snail. I was quite surprised as initially, I thought it was a pond snail, but closer inspection revealed the tell-tale eyes-on-top-of-tentacles characteristic of land snails and slugs, while aquatic snails have their eyes at the base of their tentacles. After sifting through a Molluscs guide I found out it was a Common Amber Snail, Succinea putris. Although not a........ Read more »

Biggs, H. E. J. (1968) Succinea putris (L.) in a pigeon's crop. Conchologist Newsletter, 24: 36., 36. info:other/

Shinichiro Wada, Kazuto Kawakami and Satoshi Chiba. (2011) Snails can survive passage through a bird's digestive system. Journal of Biogeography. info:/doi:10.1111/j.1365-2699.2011.02559.x

  • July 5, 2011
  • 04:11 PM

The Tertiary: Birds, Whales, Humans and Climate Change

by Marc in Teaching Biology

For PDFs of this entire talk series, click here! [17.62MB rar file with 6 PDFs] In this talk, the lack of structure that I mentioned earlier is very apparent, as we go through three not-directly-related topics. First, we will look at two select examples of vertebrates that underwent spectacular changes in the Tertiary. Second, we [...]... Read more »

Uhen, M. (2010) The Origin(s) of Whales. Annual Review of Earth and Planetary Sciences, 38(1), 189-219. DOI: 10.1146/annurev-earth-040809-152453  

Thuiller, W., Lavergne, S., Roquet, C., Boulangeat, I., Lafourcade, B., & Araujo, M. (2011) Consequences of climate change on the tree of life in Europe. Nature, 470(7335), 531-534. DOI: 10.1038/nature09705  

  • July 5, 2011
  • 03:06 PM

How to get the most out of your next vaccine? A full night's sleep may enhance protection against viral infections

by Heather in Escaping Anergy: The Immunology Research Blog

How does sleep impact our ability to properly activate our immune system? Can sleep play a role in designing better therapies and treatments for people fighting disease? These questions motivate Jan Born’s research group at the University of Lubeck in Germany to find new ways to make more efficient vaccines…without even changing the vaccine components! Learn more about the sleep trial at Escaping Anergy!... Read more »

Lange T, Dimitrov S, Bollinger T, Diekelmann S, & Born J. (2011) Sleep after vaccination boosts immunological memory. Journal of immunology (Baltimore, Md. : 1950), 187(1), 283-90. PMID: 21632713  

  • July 5, 2011
  • 11:23 AM

Human Brain Mapping (HBM) 2011

by davejhayes in neurosphere

Human Brain Mapping in Quebec City was an excellent, if not slightly overwhelming, conference which brought together the often discrepant worlds of neuroscience, psychology, psychiatry, physics, engineering, mathematics, and computer science.... Read more »

Bullmore ET, & Bassett DS. (2011) Brain graphs: graphical models of the human brain connectome. Annual review of clinical psychology, 113-40. PMID: 21128784  

Fenno L, Yizhar O, & Deisseroth K. (2011) The development and application of optogenetics. Annual review of neuroscience, 389-412. PMID: 21692661  

Lynall ME, Bassett DS, Kerwin R, McKenna PJ, Kitzbichler M, Muller U, & Bullmore E. (2010) Functional connectivity and brain networks in schizophrenia. The Journal of neuroscience : the official journal of the Society for Neuroscience, 30(28), 9477-87. PMID: 20631176  

Smith SM, Miller KL, Salimi-Khorshidi G, Webster M, Beckmann CF, Nichols TE, Ramsey JD, & Woolrich MW. (2011) Network modelling methods for FMRI. NeuroImage, 54(2), 875-91. PMID: 20817103  

  • July 5, 2011
  • 10:15 AM

Nectocaris: What the heck is this thing?

by Laelaps in Laelaps

On May 27th, 2010 paleontologists Martin Smith and Jean-Bernard Caron announced that they had found a spectacular solution to one of the fossil record’s long-running mysteries. Since its description in 1976, the 505 million year old fossil Nectocaris pteryx from British Columbia’s famous Burgess Shale had vexed scientists. Known from a single specimen – appearing [...]... Read more »

  • July 5, 2011
  • 09:49 AM

the big picture: automatic metaphor identification

by Chris in The Lousy Linguist

The recently popularized IARPA Metaphor Program piqued my curiosity, so I've been reviewing a variety of articles on contemporary approaches to automatic metaphor identification. I've read three articles so far and one thing is somewhat dissapointing: they all severely restrict the notion of metaphor to mean local metaphors within single sentences.They all pay considerable lip service to Lakoff & Johnson's seminal 1980 work Metaphors We Live By, taking as gospel the notion that metaphor is d........ Read more »

Xuri Tang, Weiguang Qu, Xiaohe Chen, & Shiwen Yu. (2010) Automatic Metaphor Recognition Based on Semantic Relation Patterns. International Conference on Asian Language Processing. info:/

  • July 5, 2011
  • 09:00 AM

Is it OK to Laugh at ‘Fat-Jokes’?

by Arya M. Sharma in Dr. Sharma's Obesity Notes

Who has not seen or heard fat jokes?
Usually a stereotypical depiction of a fat person highlighting their ‘funny’ relationship with food, their ‘facetious’ aversion to physical activity, their ‘farcical’ physical appearance, their ‘ludicrous’ clumsiness, their ‘jolly’ self-indulgence, their ‘entertaining’ lack of self-control - in short hilarious!
Not just the general public, but media, movie makers, comedians, [...]... Read more »

  • July 5, 2011
  • 08:52 AM

After Years of Belief, Confirmation: It IS a Black Hole

by Brooke N in Smaller Questions

One of the most famous black holes (for a ranked list of all famous black holes and details of their exploits, visit TMZ) is 1/2 of Cygnus X-1, a binary system in which only one companion emits light.

Astronomers have long hypothesized that the "dark star" in this binary was a black hole, but true proof did not come until last week, with the publication of three papers in the Astrophysical Journal--one precisely measuring the distance, one precisely measuring the mass, and one preci........ Read more »

Lijun Gou, Jeffrey E. McClintock, Mark J. Reid, Jerome A. Orosz, James F. Steiner, Ramesh Narayan, Jingen Xiang, Ronald A. Remillard, Keith A. Arnaud, & Shane W. Davis. (2011) The Extreme Spin of the Black Hole in Cygnus X-1. Astropyhsical Journal. arXiv: 1106.3690v1

Jerome A. Orosz, Jeffrey E. McClintock, Jason P. Aufdenberg, Ronald A. Remillard, Mark J. Reid, Ramesh Narayan, & Lijun Gou. (2011) The Mass of the Black Hole in Cygnus X-1. Astropyhsical Journal. arXiv: 1106.3689v1

Mark J. Reid, Jeffrey E. McClintock, Ramesh Narayan, Lijun Gou, Ronald A. Remillard, & Jerome A. Orosz. (2011) The Trigonometric Parallax of Cygnus X-1. Astropyhsical Journal. arXiv: 1106.3688v1

  • July 5, 2011
  • 08:06 AM

Raising the Chronically Ill Child

by Anita M. Schimizzi, Ph.D. in Child-Psych

While many of us are fortunate enough to have healthy children, not all families are so lucky.  They must confront the chronic illness of a child on a daily basis.  What are some key factors that can help them do this successfully?  Read on about an article that I came across.  March’s APA Monitor included an [...]... Read more »

Leis-Newman, E. (2011) Caring for Chronically Ill Kids: Many Parents are Struggling to Manage Their Children’s Care. Here’s Why. Monitor on Psychology, 36-39. info:/

  • July 5, 2011
  • 08:00 AM

Music and Art – Good for Your Soul and Your Lifespan

by Shaheen Lakhan in Brain Blogger

Friedrich Neitzsche once claimed that without music, life would be a mistake. Researchers in Norway claim that without music, art, or other cultural events, life may also be shorter and less satisfying. A new study, published by the Journal of Epidemiology and Community Health, reports that visiting museums, attending concerts, playing an instrument, and creating [...]... Read more »

Bygren LO, Weissglas G, Wikström BM, Konlaan BB, Grjibovski A, Karlsson AB, Andersson SO, & Sjöström M. (2009) Cultural participation and health: a randomized controlled trial among medical care staff. Psychosomatic medicine, 71(4), 469-73. PMID: 19321851  

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