Post List

  • August 26, 2010
  • 10:05 PM

Future Imagining And Episodic Memory

by Maria P. in noustuff

Neuroimaging and lesion studies suggest that imagining the future (i.e. envision future personal experiences) is strongly connected with retrospective memory (i.e. remembering past experiences). Two recent papers published on Neuropsychologia investigated the relationship of retrospective memory and future imagining, as well as their common neural correlates. Kwan, Carson, Addis, and Rosenbaum (2010) report the case [...]... Read more »

  • August 26, 2010
  • 09:41 PM

Why dictionaries don’t supply meaning : Miller on communication

by melodye in Child's Play

At the moment, I am taking a (temporary) break from my furious critiquing of peer review, and have begun working busily on a new series about the workings of human languages.  Writing about this is for a general audience is hard, particularly because I suspect that many people have unexamined intuitive views about language that [...]... Read more »

Lieven, E., Pine, J., & Baldwin, G. (1997) Lexically-based learning and the development of grammar in early multi-word speech. Journal of Child Language, 24(1), 187-219. info:/

Lieven E, Behrens H, Speares J, & Tomasello M. (2003) Early syntactic creativity: a usage-based approach. Journal of child language, 30(2), 333-70. PMID: 12846301  

  • August 26, 2010
  • 08:18 PM

Drug Shortages Affect Those Still in the Dark Ages – Furosemide

by Rogue Medic in Rogue Medic

Part 2 - Furosemide.

This drug shortage could be a good thing.

EMS may be forced to do without drugs that cause more harm than benefit.

Maybe we will be smart enough to realize that we are not helping our patients with these drugs.

Maybe.... Read more »

Mosesso VN Jr, Dunford J, Blackwell T, & Griswell JK. (2003) Prehospital therapy for acute congestive heart failure: state of the art. Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors, 7(1), 13-23. PMID: 12540139  

Mattu A, Martinez JP, & Kelly BS. (2005) Modern management of cardiogenic pulmonary edema. Emergency medicine clinics of North America, 23(4), 1105-25. PMID: 16199340  

  • August 26, 2010
  • 07:50 PM


by Rift in Psycasm

[Wherein our hero finds himself trapped for 14-hours on a dry airline. With no ready escape he resigns himself to fast-track learning a foreign language. But what's the best method...?]  As I’ve mentioned previously I’m going to The Philipinnes at the end of next week. We were lucky enough to get cheap flights, but the catch [...]... Read more »

  • August 26, 2010
  • 07:43 PM

How to Use a Journal Article to Advertise Your Product

by Neuropsych15 in The MacGuffin

From this Month's JAMA (1) "Cognitive Behavioral Therapy vs Relaxation With Educational Support for Medication-Treated Adults With ADHD and Persistent Symptoms" by Safren et al.In order to use an article to advertise your product, first you'll need to chose a topic about which people are fairly ignorant and make yourself an expert on it:“Approximately 4.4% of adults in the United States have attention-deficit/hyperactivity disorder (ADHD).” Writing Style Recommendation: If you use the word ........ Read more »

  • August 26, 2010
  • 07:20 PM

Improved Protein Minimotif Prediction for Drug Development

by Michael Long in Phased

Sanguthevar Rajasekaran (University of Connecticut, United States), Martin Schiller (University of Nevada Las Vegas, United States), and coworkers have improved upon Minimotif Miner computer software for predicting functional relationships among proteins, relevant to drug discovery. This news feature was written on August 26, 2010.... Read more »

  • August 26, 2010
  • 05:54 PM

Spices as antiseptics… maybe

by Thomas Kluyver in Thomas' Plant-Related Blog

For today, I’ve dug up a paper (I forget how) from 1998, when I was still in primary school, about why people like spicy foods, and why some cultures use more spice than others. The idea that we acquired a taste for spices to keep harmful bacteria in check isn’t implausible, but the evidence in [...]... Read more »

Billing, J., & Sherman, P. (1998) Antimicrobial Functions of Spices: Why Some Like it Hot. The Quarterly Review of Biology, 73(1), 3-49. DOI: 10.1086/420058  

  • August 26, 2010
  • 05:47 PM

Defining the link between enterotoxin production and sporulation in C. perfringens

by epibio in EpiCentral

The second most common cause of bacterial foodborne illness is Clostridium perfringens type A. These isolates produce an enterotoxin (CPE), and an estimated 250,000 cases of resultant food poisoning occur annually in the U.S. Forty years ago, it was postulated that sporulation and enterotoxin production were linked and, in fact, C. perfringens type A isolates only produce CPE during sporulation.

Four sigma factors mediate sporulation in C. perfringens; however, the exact roles of two of them (........ Read more »

Li, J. and McClane, B. (2010) Evaluating the Involvement of Alternative Sigma Factors SigF and SigG in Clostridium perfringens Sporulation and Enterotoxin Synthesis. Infect. Immun. info:/10.1128/IAI.00528-10

  • August 26, 2010
  • 05:22 PM

Inside out: cannibalism, nutrition and swarm formation in locusts

by Katie Kline in EcoTone

It may be difficult to picture just one locust singled out from a swarm. But believe it or not, desert locusts—insects infamous for their contribution to plagues and famine—are naturally solitary creatures. So what causes the group uprising that farmers are so familiar with? Research has shown that the internal workings of a solitary locust can affect the swarming behavior of the entire group.

... Read more »

Bazazi, S., Romanczuk, P., Thomas, S., Schimansky-Geier, L., Hale, J., Miller, G., Sword, G., Simpson, S., & Couzin, I. (2010) Nutritional state and collective motion: from individuals to mass migration. Proceedings of the Royal Society B: Biological Sciences. DOI: 10.1098/rspb.2010.1447  

  • August 26, 2010
  • 04:55 PM

Galaxy, a stride towards reproducible computational research

by Trey in OpenHelix

Galaxy started out as a very useful tool to do genomics research that was reproducible and sharable. One of my pet peeves in reading research papers that use genomic analysis or online genomics resources is the materials and methods sections. Often the methods and parameters used are mentioned only in a very cursory manner, if [...]... Read more »

  • August 26, 2010
  • 04:41 PM

Neury Thursday: Pharmacology Update

by Allison in Dormivigilia

Researchers have better characterized the effects of stimulatory and inhibitory pharmacological agents on the NMDA receptor, which is known to be linked to alcoholism and circadian timing. Elucidating the responsiveness of the NMDA receptor to these pharmacological agents may provide more effective treatments for alcoholism and alcohol-related disruptions to the timing of circadian phenomena (sleep/wake, hormone release). ... Read more »

Juan C. Pin˜a-Crespo,1,2* Maria Talantova,2* Ileana Micu,5* Bradley States,2 H.-S. Vincent Chen,2,4 Shichun Tu,2, Nobuki Nakanishi,2 Gary Tong,2,3 Dongxian Zhang,2 Stephen F. Heinemann,1,3 Gerald W. Zamponi,6 Peter K. Stys,5, & and Stuart A. Lipton2,3. (2010) Excitatory Glycine Responses of CNS Myelin Mediated by NR1/NR3 “NMDA” Receptor Subunits. Journal of Neuroscience, 11501-11505. info:/DOI:10.1523/JNEUROSCI.1593-10.2010

  • August 26, 2010
  • 02:01 PM

Too Cool for School – Psychrophilic oil-degrading microbes to the rescue!

by microbialmodus in Microbial Modus

This confirms that not only do a variety of hydrocarbon degrading bacterial populations exist in the newly created deep-sea oil plume, but also, as the authors state “that the microbial communities appear to be undergoing rapid dynamic adaptation in response to oil contamination.” ... Read more »

Hazen, T., Dubinsky, E., DeSantis, T., Andersen, G., Piceno, Y., Singh, N., Jansson, J., Probst, A., Borglin, S., Fortney, J.... (2010) Deep-Sea Oil Plume Enriches Indigenous Oil-Degrading Bacteria. Science. DOI: 10.1126/science.1195979  

  • August 26, 2010
  • 01:52 PM

Trojan horse predators

by Lab Rat in Lab Rat

A while ago, Angry by Choice wrote a post about a fungi that kills it's nematode prey by making little lasso ropes to catch the worm in. At the time, I thought there must be some exciting way that bacteria could cause wormy destruction, but it wasn't I read a paper from Lucas (reference below) that I actually found one.It's not as visually exciting as the little fungi nooses, but it's just as chemically exciting. As bacteria are not capable of forming phyiscal structures to capture a worm, they........ Read more »

Niu Q, Huang X, Zhang L, Xu J, Yang D, Wei K, Niu X, An Z, Bennett JW, Zou C.... (2010) A Trojan horse mechanism of bacterial pathogenesis against nematodes. Proceedings of the National Academy of Sciences of the United States of America. PMID: 20733068  

  • August 26, 2010
  • 01:22 PM

Why flour matters

by Julien Riel-Salvatore in A Very Remote Period Indeed

A couple of days ago, I mentioned how excavations at a Paleoindian site in Utah has revealed that the site's occupants had been milling various seeds to produce different kinds of flours. In that post, I mentioned how this discovery re-emphasized the fact that hunter-gatherers in general hunt as well as gather. In fact, outside of the highest latitudes, plant foods often account for a majority of... Read more »

Aranguren,Biancamaria, Becattini, Roberto, Mariotti Lippi, Marta, & Revedin, Anna. (2007) Grinding flour in Upper Palaeolithic Europe (25000 years bp). Antiquity, 81(314), 845-855. info:/

  • August 26, 2010
  • 12:43 PM

Yellowstone: what lies beneath

by Chris Rowan in Highly Allochthonous

The best evidence yet that the Yellowstone hotspot is the result of a mantle plume - one that had to burn through a subducting slab to get to the surface. Continue reading →... Read more »

Obrebski, M., Allen, R., Xue, M., & Hung, S. (2010) Slab-plume interaction beneath the Pacific Northwest. Geophysical Research Letters, 37(14). DOI: 10.1029/2010GL043489  

  • August 26, 2010
  • 12:42 PM

Measuring Gravity: Ain't Nothin' but a G Thing

by Chad Orzel in Uncertain Principles

There's a minor scandal in fundamental physics that doesn't get talked about much, and it has to do with the very first fundamental force discovered, gravity. The scandal is the value of Newton's gravitational constant G, which is the least well known of the fundamental constants, with a value of 6.674 28(67) x 10-11 m3 kg-1 s-2. That may seem pretty precise, but the uncertainty (the two digits in parentheses) is scandalously large when compared to something like Planck's constant at 6.626 068 9........ Read more »

Schlamminger, S., Holzschuh, E., Kündig, W., Nolting, F., Pixley, R., Schurr, J., & Straumann, U. (2006) Measurement of Newton’s gravitational constant. Physical Review D, 74(8). DOI: 10.1103/PhysRevD.74.082001  

Luo, J., Liu, Q., Tu, L., Shao, C., Liu, L., Yang, S., Li, Q., & Zhang, Y. (2009) Determination of the Newtonian Gravitational Constant G with Time-of-Swing Method. Physical Review Letters, 102(24). DOI: 10.1103/PhysRevLett.102.240801  

Harold V. Parks, & James E. Faller. (2010) A Simple Pendulum Determination of the Gravitational Constant. Physical Review Letters (accepted). arXiv: 1008.3203v2

  • August 26, 2010
  • 12:22 PM

More good progress for experimental cancer drug

by Cancer Research UK in Cancer Research UK - Science Update

Last September, we covered results from a small trial of an experimental drug called PLX4032, which has been developed to treat patients whose cancers are caused by a faulty version of a gene called BRAF. Today, yet more encouraging results were announced in the New England Journal of Medicine, which were reported widely in the [...]... Read more »

Flaherty, K., Puzanov, I., Kim, K., Ribas, A., McArthur, G., Sosman, J., O'Dwyer, P., Lee, R., Grippo, J., Nolop, K.... (2010) Inhibition of Mutated, Activated BRAF in Metastatic Melanoma. New England Journal of Medicine, 363(9), 809-819. DOI: 10.1056/NEJMoa1002011  

  • August 26, 2010
  • 11:00 AM

Silver Spoon Hyenas?

by Jason Goldman in The Thoughtful Animal

A fascinating new paper just came out in Nature Communications and I intend to blog it in the usual manner, but I thought I'd try something new first. Check it out:

The Research Question...According to life history theory, mothers should invest in their offspring if this enhances offspring survival and fitness, and if the fitness benefit to mothers from increased offspring fitness exceeds the cost of their investment. Whether the maternal environment influences the fitness and reproductive v........ Read more »

Höner, O., Wachter, B., Hofer, H., Wilhelm, K., Thierer, D., Trillmich, F., Burke, T., & East, M. (2010) The fitness of dispersing spotted hyaena sons is influenced by maternal social status. Nature Communications, 1(5), 1-7. DOI: 10.1038/ncomms1059  

  • August 26, 2010
  • 10:55 AM

Why A Good Friend Has the Same Effect As a Warm Fire

by David Berreby in Mind Matters

"Vision," Stanford's Bill Newsome likes to say, "does not happen in the eye. It happens in the brain." As I mentioned in my last post, this is a general theme in our understanding of the mind and brain: We don't passively record "reality" and then process our perceptions. Rather, we actively create what we see, hear, taste, smell and feel. A nice new example is this experiment, which found that people feel warmer when standing near a loved one, and colder when they're reminded that........ Read more »

  • August 26, 2010
  • 10:05 AM

Fossil Plant Debris Key to UK Dinosaur Preservation

by Brian Switek in Dinosaur Tracking

When I think of dinosaur bones, the rocky and shrub-flecked expanses of western North America immediately come to mind, but it should not be forgotten that some of the first dinosaurs recognized by science were discovered across the Atlantic in England. Paleontologists have been searching for dinosaurs there longer than anywhere else, and among the [...]... Read more »

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