Post List

  • September 19, 2011
  • 07:00 AM

September 19, 2011

by Erin Campbell in HighMag Blog

“Shock and awe” may be a good strategy if you’re planning an attack on ne’er-do-wells, but it really is a terrible strategy if you’re fine-tuning a nervous system. Instead the nervous system uses diplomacy in its refinement, and a recent paper describes a savvy signaling pathway that does the job.During development, the nervous system refines its connections through removal of neuronal processes and elimination of excess neurons. Neuron removal takes place through apoptosis, or progr........ Read more »

Sengupta Ghosh, A., Wang, B., Pozniak, C., Chen, M., Watts, R., & Lewcock, J. (2011) DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activity. originally published in The Journal of Cell Biology, 194(5), 751-764. DOI: 10.1083/jcb.201103153  

  • September 19, 2011
  • 06:26 AM

How to break free of the wrong career

by Fiona Beukes in Ona76

I’m so glad that I have found Herminia Ibarra (2002) articles. She has a lot of useful comments on personal and career development. She is also very practically focused, which suits my EBI requirements. Ibarra (2002) also has a different take on the whole career redevelopment approach, which is outlined in her Harvard Business Review article [...]... Read more »

Ibarra H. (2002) How to stay stuck in the wrong career. Harvard business review, 80(12), 40. PMID: 12510536  

Kolb, D.A., & Fry, R. (1975) Towards an Applied Theory of experiential learning. Theories of Group Processes, 33-57. info:/

  • September 19, 2011
  • 05:09 AM

Here we go again

by Janet Kwasniak in Thoughts on thoughts

Sometime soon I will have to stop rising to what is said about free will. I started this posting in response to K. Smith’s article (see citation below) because the article seemed a way to confuse rather than to clarify. I almost finished when I read the sensible blog by Bjoern Brembs (here) with which [...]... Read more »

  • September 18, 2011
  • 10:22 PM

Neury Thursday: Adenosine Increases Drug Permeability

by Allison in Dormivigilia

Researchers reported in this week's Journal of Neuroscience that co-activation of adenosine receptor subtypes, A1 and A2, additively increases the permeability of macromolecules across the blood-brain barrier. This could result in huge, rapid advancements in drug development and for finding efficacious treatment strategies for at present incurable neurologic diseases such as Alzheimer's... Read more »

Aaron J. Carman, Jeffrey H. Mills, Antje Krenz, Do-Geun Kim, and Margaret S. Bynoe. (2011) Adenosine Receptor Signaling Modulates Permeability of the Blood–Brain Barrier. Journal of Neuroscience. info:/10.1523/JNEUROSCI.3337-11.2011

  • September 18, 2011
  • 10:05 PM

Exercise and Your Immune System Revisited

by Elizabeth Preston in Inkfish

It's not every day I get an email from someone in Taiwan about exercise, white blood cells, and menstruation. But in response to my post How Much Exercise Harms Your Immune System?, Guan-Da Syu from National Cheng Kung University Medical College dropped me a friendly note (if you can call an email with its own bibliography a "note") a few days ago. Syu is the lead author of the paper I'd discussed in that post, and he wanted to respond to some questions I raised.

T........ Read more »

  • September 18, 2011
  • 09:06 PM

[insert clever quip about australopithecus hips]

by zacharoo in Lawn Chair Anthropology

A week and a half ago, Kibii and colleagues (2011) published reconstructions and re-analyses of two hips belonging to the 1.98 million-year old Australopithecus sediba. As with many fossil discoveries, these additions to the fossil record raise more questions than they answer. Unless the question was, "did A. sediba have a pelvis?" It did. Here's a good summary from the paper itself:Thus, Au. sediba is australopith-like in having a long superior pubic ramus and an anteriorly posit........ Read more »

Haile-Selassie Y, Latimer BM, Alene M, Deino AL, Gibert L, Melillo SM, Saylor BZ, Scott GR, & Lovejoy CO. (2010) An early Australopithecus afarensis postcranium from Woranso-Mille, Ethiopia. Proceedings of the National Academy of Sciences of the United States of America, 107(27), 12121-6. PMID: 20566837  

Kibii, J., Churchill, S., Schmid, P., Carlson, K., Reed, N., de Ruiter, D., & Berger, L. (2011) A Partial Pelvis of Australopithecus sediba. Science, 333(6048), 1407-1411. DOI: 10.1126/science.1202521  

Simpson, S., Quade, J., Levin, N., Butler, R., Dupont-Nivet, G., Everett, M., & Semaw, S. (2008) A Female Homo erectus Pelvis from Gona, Ethiopia. Science, 322(5904), 1089-1092. DOI: 10.1126/science.1163592  

Zipfel, B., DeSilva, J., Kidd, R., Carlson, K., Churchill, S., & Berger, L. (2011) The Foot and Ankle of Australopithecus sediba. Science, 333(6048), 1417-1420. DOI: 10.1126/science.1202703  

  • September 18, 2011
  • 08:29 PM

Account for the Graying of Your Jury Pool

by Persuasion Strategies in Persuasive Litigator

By Dr. Ken Broda-Bahm - In a recent viral video on YouTube an old couple peers into a computer webcam, trying to figure out how to operate the device, not realizing that they are recording themselves. Beyond providing a charming vignette, the clip might also be seen as a window into the future of the American jury. As the pool of eligible and available jurors continues to get older, there are a few things to take into account, and a few misconceptions that the research tells us to set aside. Old........ Read more »

Darrell Worthy, Marissa Gorlick, Jennifer Pacheco, David Schnyer, W. Todd Maddox. (2011) With Age Comes Wisdom: Decision-Making in Younger and Older Adults. Psychological Science. info:/

  • September 18, 2011
  • 05:21 PM

Bugs in bugs in bugs

by microbelog in Microbelog

Symbiotic relationships, where organisms of different species work together for mutual gain, have been studied extensively in numerous biological systems, but modern genomic techniques are revolutionising our understanding of how these interactions work at the molecular level. A recent paper by John McCutcheon and Carol von Dohlen has reported an interesting case of a ‘three-way symbiosis’ between [...]... Read more »

  • September 18, 2011
  • 11:16 AM

Listening to Rivers

by Brian Romans in Clastic Detritus

Rivers are the great conveyors of material across the Earth’s surface. Determining how much and at what rate material, both solid and dissolved, is moved from one place to another is critical for understanding how rivers interact with ecosystems. Importantly, predicting the timing and magnitude of floods that occur in the ecosystem known as human [...]... Read more »

  • September 18, 2011
  • 09:33 AM

Is an HIV vaccine finally possible? Unraveling the secrets of broadly neutralizing antibodies

by EE Giorgi in CHIMERAS

Last month I talked about the daunting challenge that HIV has presented for the past thirty years. HIV is so variable that as soon as the immune system builds a defense against it, the virus comes up with a new variant that allows it to escape. The only way to defeat such an elusive enemy is with immune responses able to recognize a broad range of HIV subtypes and variants. Unfortunately, antibodies with these characteristics are produced by a minority of patients and only years into the infecti........ Read more »

Wu, X., Zhou, T., Zhu, J., Zhang, B., Georgiev, I., Wang, C., Chen, X., Longo, N., Louder, M., McKee, K.... (2011) Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing. Science, 333(6049), 1593-1602. DOI: 10.1126/science.1207532  

Scheid, J., Mouquet, H., Ueberheide, B., Diskin, R., Klein, F., Oliveira, T., Pietzsch, J., Fenyo, D., Abadir, A., Velinzon, K.... (2011) Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding. Science, 333(6049), 1633-1637. DOI: 10.1126/science.1207227  

  • September 18, 2011
  • 05:26 AM

The Phenomenology of Pain During REM Sleep

by The Neurocritic in The Neurocritic

Coarse — Pain in DreamsHave you ever felt pain in dreams? I have. Once I dreamed I was lying on my stomach, getting a tattoo on my calf against my will. Because it was a particularly malevolent tattoo studio, I cried out in the dream. When I woke up, I felt no pain at all. It was false, a figment of the Pain Matrix. Another time a monkey bit me on the arm. Once again, the pain vanished upon awakening.I think these examples of what I'll call "fake pain" are unusual. More common are instances wh........ Read more »

Nielsen TA, McGregor DL, Zadra A, Ilnicki D, & Ouellet L. (1993) Pain in dreams. Sleep, 16(5), 490-8. PMID: 7690981  

  • September 17, 2011
  • 10:16 PM

If Judas were a bacterium

by Saucy Knave in Jester's Court

When it comes to gardening, yours truly is a wannabe. I own a few potted plants, but I live in an apartment and I don't have a yard, so there's a limit to what I can do. Nonetheless, I love and appreciate plants, which probably explains the deep and irrational loathing I feel for aphids. I know they're part of the Natural Order of Things, but to be quite frank I hate the sapsuckers anyway. Biodiversity be bothered -- if they disappeared from the face of the Earth tomorrow, I would........ Read more »

Leroy PD, Sabri A, Heuskin S, Thonart P, Lognay G, Verheggen FJ, Francis F, Brostaux Y, Felton GW, & Haubruge E. (2011) Microorganisms from aphid honeydew attract and enhance the efficacy of natural enemies. Nature communications, 348. PMID: 21673669  

  • September 17, 2011
  • 08:07 PM

Hope for Lynx

by Vivek Venkataraman in sciencebyte

The Iberian Lynx, one of the most critically endangered species of wildcats, may not be doomed to extinction after all... Read more »

RODRÍGUEZ, R., RAMÍREZ, O., VALDIOSERA, C., GARCÍA, N., ALDA, F., MADURELL-MALAPEIRA, J., MARMI, J., DOADRIO, I., WILLERSLEV, E., GÖTHERSTRÖM, A.... (2011) 50,000 years of genetic uniformity in the critically endangered Iberian lynx. Molecular Ecology, 20(18), 3785-3795. DOI: 10.1111/j.1365-294X.2011.05231.x  

  • September 17, 2011
  • 10:59 AM

The Psychology of Pleasure: Interview With Paul Bloom

by Sam McNerney in Why We Reason

In 1986, CEO of Perrier North America Bruce Nevins found himself in a difficult spot. On KABC radio in Los Angeles the host challenged him to a blind taste test. The rules were simple: correctly identify a Perrier from seven drinks – six club sodas and one Perrier. Long story short, Nevins failed miserably; it [...]... Read more »

Newman, G., Diesendruck, G., & Bloom, P. (2011) Celebrity Contagion and the Value of Objects. Journal of Consumer Research, 38(2), 215-228. DOI: 10.1086/658999  

  • September 17, 2011
  • 08:33 AM

How does spatial distance between partners affect their feeling of jealousy?

by Farid Pazhoohi in Epistemophil

A new study that is appeared in journal of Evolutionary Psychology, investigated effect of distance of partner and closeness of the rival person on jealousy. Study showed that spatial distance affects the intensity of jealousy. An amazing finding is that although men felt comfortable near their partner and far from the rival person, women still felt a bit jealous while they were with their men and far from the rival women.
In short, this study showed that “the jealousy mechanism responds w........ Read more »

Schützwohl, A., Morjaria, S., and Alvis, S. (2011) Spatial Distance Regulates Sex-Specific Feelings to Suspected Sexual and Emotional Infidelity. Evolutionary Psychology. info:/

  • September 17, 2011
  • 05:57 AM

How dangerous are viral quasispecies?

by Connor Bamford in The Rule of 6ix

Chikungunya virus particles emerging from an infected cell - is genetic diversity important to this virus?


   At around 1 mutation per 1,000 - 100,000 nucleotides per round of replication, RNA viruses have the highest mutation rate of anything seen in nature to date. During an infection of a single cell, thousands of new genomes are produced that will go on to make new virus particles; each genome will differ from another at most maybe 10 nucleotides (given an avera........ Read more »

Coffey, L., Beeharry, Y., Borderia, A., Blanc, H., & Vignuzzi, M. (2011) Arbovirus high fidelity variant loses fitness in mosquitoes and mice. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1111650108  

  • September 17, 2011
  • 02:29 AM

How long as the Atacama been dry?

by Lab Lemming in Lounge of the Lab Lemming

“I am flying home from Europe in late August with nothing but a notebook and the 2011 Goldschmidt conference Geology giveaway issue to keep me occupied. Using the old-fashioned method of reading and writing on paper, I will blog my way through the compilation of highlighted geochemistry papers as time allows. These will then be posted via time delay to keep the blog moving while preventing ... Read more »

  • September 16, 2011
  • 08:53 PM

How many pixels make an object? Like, 30

by Patrick Mineault in xcorr

There’s a neat paper on the psychophysics of scene and object recognition in super-low resolution scenarios in Visual Neuroscience by A. Torralba (2009). The author sought to answer a rather interesting question: what image resolution is needed to support scene and object recognition? He took images from databases and created several different versions of them, [...]... Read more »

Torralba A. (2009) How many pixels make an image?. Visual neuroscience, 26(1), 123-31. PMID: 19216820  

  • September 16, 2011
  • 06:23 PM

Predictors of PTSD in children and adults

by Eva Alisic in Trauma Recovery

We know that traumatic events occur quite often. We also know that most people are resilient, even though many survivors experience some distress in the direct aftermath of an event. Only a minority will develop longer-term stress symptoms. What are their characteristics? Who is ‘at risk’ after trauma? ... Read more »

Alisic, E., Jongmans, M., van Wesel, F., & Kleber, R. (2011) Building child trauma theory from longitudinal studies: A meta-analysis. Clinical Psychology Review, 31(5), 736-747. DOI: 10.1016/j.cpr.2011.03.001  

  • September 16, 2011
  • 05:48 PM

Thank you Mario! But your methods are in another field!

by Bradley Voytek in Oscillatory Thoughts

My love for video games is no secret. I just finished Mass Effect 2 and started Dragon Age 2 (I'm a sucker for Bioware RGPs).One of the first true peer-review papers I remember reading was Green & Bavelier's 2003 Nature paper "Action video game modifies visual selective attention". In that study the authors performed a series of experiments showing that people who had a lot of experience playing "action video games" performed better than non-video game players on a variety of attention tasks. Pa........ Read more »

Owen, A., Hampshire, A., Grahn, J., Stenton, R., Dajani, S., Burns, A., Howard, R., & Ballard, C. (2010) Putting brain training to the test. Nature, 465(7299), 775-778. DOI: 10.1038/nature09042  

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