Last night I was eating dinner at Rubio's (side note: "Baja Fresh," Rubio's slogan is a little confusing considering that their fish tacos are made with Alaskan pollock, just an observation) while surfing the web using my smartphone. What I found was shocking: an article released by the Science Magazine, states that dutch social psychologist Diedrik Stapel has "admitted to using faked data" and "will not be asked to return" to Tilburg University where he is........ Read more »
Division of labor is a major part of understanding gender and class roles in historic populations. Without text, archaeologists depend on material and human remains for the answers. The physical stress (or lack thereof) from daily activities can leave markers … Continue reading →... Read more »
P. HAVELKOVA, S. VILLOTTE, P. VELEMINSKY, L. POLACEK AND M. DOBISIKOVA. (2011) Enthesopathies and Activity Patterns in the Early Medieval Great Moravian Population: Evidence of Division of Labor. International Journal of Osteoarchaeology, 487-504. info:/
In February 1942, the city of Singapore was lost to the Japanese army during the Malaya campaign of World War II. The Fall of Singapore is considered to be one of the greatest British military disasters, with over 100,000 Allied troops consisting of British, Australian, American and Dutch soldiers captured. Several thousands of these men were sent to the Thai-Burma border to finish construction of the Burma Railway, known as the "Death Railway". Several medical surveys of these former ........ Read more »
Prendki V, Fenaux P, Durand R, Thellier M, & Bouchaud O. (2011) Strongyloidiasis in man 75 years after initial exposure. Emerging infectious diseases, 17(5), 931-2. PMID: 21529417
Imagine a system where we intentionally ignore the usual horribly inaccurate trauma triage criteria, such as MOI (Mechanism Of Injury). And these are not even the usual criteria, because this is in a system with criteria already modifieded to avoid a lot of overtriage. :-)... Read more »
Teleost fish genome sequences have been absolutely essential to our understanding of vertebrate genome evolution, and to vertebrate evolution in general. Last month I welcomed the addition of the Atlantic cod genome to the sequenced fish genomes, and highlighted some of the main findings of the first analysis of the whole genome sequence. The preliminary genome database is now available for browsing at the Pre!Ensembl database.
After I had written that post, I had some notes left over becaus........ Read more »
Star, B., Nederbragt, A., Jentoft, S., Grimholt, U., Malmstrøm, M., Gregers, T., Rounge, T., Paulsen, J., Solbakken, M., Sharma, A.... (2011) The genome sequence of Atlantic cod reveals a unique immune system. Nature. DOI: 10.1038/nature10342
Judging by its starlight and gas content (as seen in the image above), Eris looks to be a near match for our own Milky Way galaxy — except that it exists only as a simulation inside a supercomputer...... Read more »
Javiera Guedes, Simone Callegari, Piero Madau, & Lucio Mayer. (2011) Forming Realistic Late-Type Spirals in a LCDM Universe: The Eris Simulation. Astrophysical Journal. arXiv: 1103.6030v2
by Persuasion Strategies in Persuasive Litigator
Your case has finally gone to the jury, and the panel is now ensconced in the jury room. What are they doing in there? Are they carefully and logically arguing the merits of your case, considering all sides until the truth wins out? If you have ever watched a closed-circuit feed of mock jury deliberations, or talked in detail with actual jurors after a verdict, you know the answer is, "No, not really doing that." What they are likely doing instead is using argument instrumentally, as a tool ........ Read more »
Mercier H, & Sperber D. (2011) Why do humans reason? Arguments for an argumentative theory. The Behavioral and brain sciences, 34(2), 57. PMID: 21447233
A few weeks ago I was discussing possible relevant papers for the Twitter Journal Club (Hashtag #TwitJC), a succesful initiative on Twitter, that I have discussed previously here and here [7,8]. I proposed an article, that appeared behind a paywall. Annemarie Cunningham (@amcunningham) immediately ran the idea down, stressing that open-access (OA) is a pre-requisite for the TwitJC [...]... Read more »
Björk, B., Welling, P., Laakso, M., Majlender, P., Hedlund, T., & Guðnason, G. (2010) Open Access to the Scientific Journal Literature: Situation 2009. PLoS ONE, 5(6). DOI: 10.1371/journal.pone.0011273
Matsubayashi, M., Kurata, K., Sakai, Y., Morioka, T., Kato, S., Mine, S., & Ueda, S. (2009) Status of open access in the biomedical field in 2005. Journal of the Medical Library Association : JMLA, 97(1), 4-11. DOI: 10.3163/1536-5050.97.1.002
Murali NS, Murali HR, Auethavekiat P, Erwin PJ, Mandrekar JN, Manek NJ, & Ghosh AK. (2004) Impact of FUTON and NAA bias on visibility of research. Mayo Clinic proceedings. Mayo Clinic, 79(8), 1001-6. PMID: 15301326
Carney PA, Poor DA, Schifferdecker KE, Gephart DS, Brooks WB, & Nierenberg DW. (2004) Computer use among community-based primary care physician preceptors. Academic medicine : journal of the Association of American Medical Colleges, 79(6), 580-90. PMID: 15165980
Krieger, M., Richter, R., & Austin, T. (2008) An exploratory analysis of PubMed's free full-text limit on citation retrieval for clinical questions. Journal of the Medical Library Association : JMLA, 96(4), 351-355. DOI: 10.3163/1536-5050.96.4.010
Daily work-related energy expenditure over the last half-century in the U.S. has decreased by over 100 calories. This may well explain the increase in body weights we’ve seen, according to a 2011 article in PLoS ONE.
I sorta hate to open this can o’ worms, but it’s important. As a population, are we fat because we eat too much [...]... Read more »
Church, T., Thomas, D., Tudor-Locke, C., Katzmarzyk, P., Earnest, C., Rodarte, R., Martin, C., Blair, S., & Bouchard, C. (2011) Trends over 5 Decades in U.S. Occupation-Related Physical Activity and Their Associations with Obesity. PLoS ONE, 6(5). DOI: 10.1371/journal.pone.0019657
During a pivotal scene in West Side Story, the Jets and the Sharks meet to prepare to rumble. As the gangs assembled each side likely tried to assess their opponent’s strength. This ability to assess numerical advantage is highly advantageous in any species where conflict between groups is common.
Spotted hyenas (Crocuta crocuta) live in large fission-fussion clans where smaller groups often forage separately (Figure 1). The composition and size of these subgroups varies over time ........ Read more »
Benson-Amram, S., Heinen, V., Dryer, S., & Holekamp, K. (2011) Numerical assessment and individual call discrimination by wild spotted hyaenas, Crocuta crocuta. Animal Behaviour. DOI: 10.1016/j.anbehav.2011.07.004
Researchers have long known about regeneration of injured muscles, and have debated about the exact source of the muscle stem cells that perform this amazing feat. A group of papers in a recent issue of Development shine a stem cell spotlight on satellite cells. Following injury, skeletal muscles are regenerated by muscle stem cells, but [...]... Read more »
Lepper, C., Partridge, T., & Fan, C. (2011) An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration. Development, 138(17), 3639-3646. DOI: 10.1242/dev.067595
More evidence that acacia trees had a role to play in the evolution of langauge.... Read more »
Sean Geraint. (2011) Language Evolution and the Acacia Tree. Speculative Grammarian, Vol CLXII(4). info:/
A interesting history lesson & discussion on the 100 year old debate - are viruses alive?... Read more »
Moreira D, & López-García P. (2009) Ten reasons to exclude viruses from the tree of life. Nature reviews. Microbiology, 7(4), 306-11. PMID: 19270719
Cardiopulmonary BypassCardiopulmonary Bypass (source) More than 1,000 adult and 50 pediatric patients undergo a surgery involving cardiopulmonary bypass (CPB) each day in the United States. A CPB is used when performing surgery on the heart or lungs, leaving them unable to perform their normal functions. But CPB introduces a lot of foreign material to the body, creating adverse reactions. The CPB assembly, drugs and surgical processes can each have t........ Read more »
Aran, K., Fok, A., Sasso, L., Kamdar, N., Guan, Y., Sun, Q., Ündar, A., & Zahn, J. (2011) Microfiltration platform for continuous blood plasma protein extraction from whole blood during cardiac surgery. Lab on a Chip, 11(17), 2858. DOI: 10.1039/C1LC20080A
So after lab meeting, I’m going to grab a drink at the plus end of a microtubule. I hear it’s a swingin’ place, with lots of cool things going on. I also hear a kinesin-8 is a real mover and shaker at the plus end, but you’ll have to check out today’s image to see for yourself.
The structure and function of the mitotic spindle depends on the amazing qualities of microtubules. Microtubules grow and shorten from their plus ends (mostly), which are the ends that reach out towards the........ Read more »
Stout, J., Yount, A., Powers, J., LeBlanc, C., Ems-McClung, S., & Walczak, C. (2011) Kif18B interacts with EB1 and controls astral microtubule length during mitosis. Molecular Biology of the Cell, 22(17), 3070-3080. DOI: 10.1091/mbc.E11-04-0363
Fusion proteins are produced when mutations combine coding sequences from two separate genes. These proteins can be oncogenic, and a team of researchers from the USA, Israel and Spain have discovered gene sequences that could produce fusion proteins in colorectal cancer.... Read more »
Bass, A., Lawrence, M., Brace, L., Ramos, A., Drier, Y., Cibulskis, K., Sougnez, C., Voet, D., Saksena, G., Sivachenko, A.... (2011) Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion. Nature Genetics. DOI: 10.1038/ng.936
by Dario Dieguez, Jr, PhD in Brain Blogger
Social neuroscience is a rapidly growing discipline that examines the relationship between the brain and social behavior. The “social brain hypothesis” posits that, over evolutionary time, living in large, social groups favored the physical growth of brain regions important for social behavior. In non-human primates, some evidence indicates that the size of the amygdala is [...]... Read more »
Bickart KC, Wright CI, Dautoff RJ, Dickerson BC, & Barrett LF. (2011) Amygdala volume and social network size in humans. Nature neuroscience, 14(2), 163-4. PMID: 21186358
Hartley CA, & Phelps EA. (2010) Changing fear: the neurocircuitry of emotion regulation. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 35(1), 136-46. PMID: 19710632
Lewis KP, & Barton RA. (2006) Amygdala size and hypothalamus size predict social play frequency in nonhuman primates: a comparative analysis using independent contrasts. Journal of comparative psychology (Washington, D.C. : 1983), 120(1), 31-7. PMID: 16551162
Monfils MH, Cowansage KK, Klann E, & LeDoux JE. (2009) Extinction-reconsolidation boundaries: key to persistent attenuation of fear memories. Science (New York, N.Y.), 324(5929), 951-5. PMID: 19342552
Schiller D, Monfils MH, Raio CM, Johnson DC, Ledoux JE, & Phelps EA. (2010) Preventing the return of fear in humans using reconsolidation update mechanisms. Nature, 463(7277), 49-53. PMID: 20010606
by Paul O'Neill in the Node
Transparency. A desirable virtue in many walks of life, and a particularly useful trait in developmental biology. Model organisms that are see-through offer unique advantages, especially when it comes to detailed 3D imaging. A new report in Nature Neuroscience offers a potential advance in this area. Researchers from Japan have stumbled upon a novel aqueous [...]... Read more »
Hama, H., Kurokawa, H., Kawano, H., Ando, R., Shimogori, T., Noda, H., Fukami, K., Sakaue-Sawano, A., & Miyawaki, A. (2011) Scale: a chemical approach for fluorescence imaging and reconstruction of transparent mouse brain. Nature Neuroscience. DOI: 10.1038/nn.2928
The reportedly 5.5 foot long, 25 pound rattlesnake
This morning I was made aware of a large Eastern Diamondback Rattlesnake that had been captured on Hilton Head Island in South Carolina. This in itself isn't too surprising, the species can range up to North Carolina and are often found on barrier islands. Although, there isn't much habitat left for snakes on these islands because they are ... Read more »
D. B. Means. (2009) EFFECTS OF RATTLESNAKE ROUNDUPS ON THE EASTERN DIAMONDBACK RATTLESNAKE (CROTALUS ADAMANTEUS). Herpetological Conservation and Biology, 4(2). info:/
I love eating meat. It’s no secret that I would probably be strictly carnivorous if it were just as easy to whip up a half-rack of ribs as it is to pour a bowl of cereal. Alas, meat preparation can be relatively involved, so I don’t eat it with every meal. But I do get what I call “protein deprivation” headaches if I have to go more than, say, 24 hours without meat.
All of this is to say that I have a vested interest in knowing I have a reliable supply of meat of avail........ Read more »
Tuomisto HL, & de Mattos MJ. (2011) Environmental impacts of cultured meat production. Environmental science , 45(14), 6117-23. PMID: 21682287
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