As researchers, we hope that when politicians are making decisions about policy, they use our research to help ground their thinking. In Canada, CIHR (Canadian Institutes of Health Research), encourages researchers to make their work accessible, and has specific grant applications focused on Knowledge Translation (KT). Part of the trouble with evaluating whether or not [...]... Read more »
Orton L, Lloyd-Williams F, Taylor-Robinson D, O'Flaherty M, & Capewell S. (2011) The use of research evidence in public health decision making processes: systematic review. PloS one, 6(7). PMID: 21818262
We here in the U.S. tend to think of death and burial as little as possible. Someone dies, and we bury them. Perhaps we visit the person's grave or other sacred space on occasion, but that's the extent of our interaction with the dead. In other places and in other times, people weren't so squeamish about death and had a continuing relationship with the dead bodies of their compatriots.
Secondary burial is usually defined as anything other than putting a dead body in the ground........ Read more »
Killgrove, K. (2009) Rethinking taxonomies: skeletal variation on the North Carolina coastal plain. Southeastern Archaeology, 28(1), 87-100. info:/
Brief overview of the role of chemotaxis in yeast mating, plus new research on highly efficient and dynamic cell-to-cell signaling during yeast mating.... Read more »
Meng Jin,1 Beverly Errede,1* Marcelo Behar,2 Will Mather,3 Sujata Nayak,3 Jeff Hasty,3, & Henrik G. Dohlman,1,4 Timothy C. Elston4*. (2011) Yeast Dynamically Modify Their Environment to Achieve Better Mating Efficiency. Science Signaling , 4(186). info:/
A supply chain usually does not stand alone. Frequently a supply chain is defined by the need of the end customer which has to be satisfied. Since one company commonly deliver several products, within a single company there can be multiple different supply chains aggregated under one organization. This task of managing multiple supply chains is most often referred to as Supply Chain Portfolio Management. It is still in a very early stage of research, so there are only few researchers focusing on........ Read more »
Seifert, R.W., & Langenberg, K.U. (2011) Managing Business Dynamics with Adaptive Supply Chain Portfolios. European Journal of Operational Research. info:/
Today in Mumbai (India), at the Lepton-Photon 2011 Conference, talks announcing new results from LHC were held. Data taking claimed almost doubling of data since July Conference in Grenoble. The results were striking and somewhat unexpected. In order to have an idea you should read this CERN press release and the general mood of people [...]... Read more »
The eating disorders anorexia nervosa and bulimia nervosa share some common features. Excessive fear of being fat is a core feature of both disorders. However, key clinical differences between the disorders exist.Most patients with bulimia nervosa are in the normal to overweight category. Anorexia nervosa by definition requires being of low weight, often to such extreme levels to pose a danger of death due to the effects of starvation.Now we have a study using fMRI that examine........ Read more »
Brooks, S., O′Daly, O., Uher, R., Friederich, H., Giampietro, V., Brammer, M., Williams, S., Schiöth, H., Treasure, J., & Campbell, I. (2011) Differential Neural Responses to Food Images in Women with Bulimia versus Anorexia Nervosa. PLoS ONE, 6(7). DOI: 10.1371/journal.pone.0022259
So it happened again. We do a lot of pre-trial research and observe a lot of both mock jurors and the dynamics related to presiding jurors. This past weekend, we re-experienced the frustration of how bad it can be when you get a controlling and dominant presiding juror. In a real jury, a dominant presiding [...]
Related posts:Deliberations & the role of the presiding juror
Educating Jurors: How NOT to start deliberations
Mistrials due to lawyers making faces, internet misconduct &........ Read more »
Koenig AM, Eagly AH, Mitchell AA, & Ristikari T. (2011) Are leader stereotypes masculine? A meta-analysis of three research paradigms. Psychological Bulletin, 137(4), 616-42. PMID: 21639606
There are some images that just stick with you. They might be beautiful, fascinating, or terrifying. For example, I’ll never forget when my former labmates told me to Google pictures of a teratoma. Seriously, don’t do it…wait, you just did, didn’t you? Unless you are a C. elegans worm, you won’t find today’s images terrifying…instead, you are likely to be utterly fascinated.
C. elegans are small 1mm-long roundworms that are used extensively in biology research. When the head ........ Read more »
Maguire, S., Clark, C., Nunnari, J., Pirri, J., & Alkema, M. (2011) The C. elegans Touch Response Facilitates Escape from Predacious Fungi. Current Biology, 21(15), 1326-1330. DOI: 10.1016/j.cub.2011.06.063
Psychologists in the Netherlands have documented the case of a 58-year-old woman who was misdiagnosed with Alzheimer's Disease. The would-be patient consulted a neurologist at a stressful time in her life, in the knowledge that her mother had had the illness. A brain scan indicated reduced activity at the front of her brain ("hypofrontality"), and the neurologist also estimated her performance on a test of cognitive impairment as poor (though no formal test was conducted). On this basis he diagn........ Read more »
Merckelbach, H., Jelicic, M., & Jonker, C. (2011) Planting a misdiagnosis of Alzheimer's disease in a person's mind. Acta Neuropsychiatrica. DOI: 10.1111/j.1601-5215.2011.00586.x
We hear a lot about the value of getting ten thousand steps a day. Pedometers are being sold increasingly as a way to track progress towards that magic 10k. But is there any basis in this assertion of ten thousand steps that something wonderful happens at 10k that doesn't anywhere before (or after)? And are all such steps in that 10k created equal? Are all or any of these steps the same as NEPAs or non-exercise physical activity (overview here at nopain2.org)- the movement carried out over........ Read more »
Tudor-Locke C, Craig CL, Aoyagi Y, Bell RC, Croteau KA, De Bourdeaudhuij I, Ewald B, Gardner AW, Hatano Y, Lutes LD.... (2011) How many steps/day are enough? For older adults and special populations. The international journal of behavioral nutrition and physical activity, 8(1), 80. PMID: 21798044
Tudor-Locke C, Craig CL, Beets MW, Belton S, Cardon GM, Duncan S, Hatano Y, Lubans DR, Olds TS, Raustorp A.... (2011) How Many Steps/day are Enough? For Children and Adolescents. The international journal of behavioral nutrition and physical activity, 8(1), 78. PMID: 21798014
Individual atoms speed up chemical reactions... Read more »
Qiao, B., Wang, A., Yang, X., Allard, L., Jiang, Z., Cui, Y., Liu, J., Li, J., & Zhang, T. (2011) Single-atom catalysis of CO oxidation using Pt1/FeOx. Nature Chemistry, 3(8), 634-641. DOI: 10.1038/nchem.1095
Is it just me, or are biomedical papers about searching for a systematic review often of low quality or just too damn obvious? I’m seldom excited about papers dealing with optimal search strategies or peculiarities of PubMed, even though it is my specialty. It is my impression, that many of the lower quality and/or less relevant papers are [...]... Read more »
Winchester DE, & Bavry AA. (2010) Limitations of the MEDLINE database in constructing meta-analyses. Annals of internal medicine, 153(5), 347-8. PMID: 20820050
Leclercq E, Kramer B, & Schats W. (2011) Limitations of the MEDLINE database in constructing meta-analyses. Annals of internal medicine, 154(5), 371. PMID: 21357916
The other day, psychologist Tom Hartley tweeted "Your reflection is always half the size of the real thing - no matter how far from mirror. Hard to believe but true." and linked to this post in which someone demonstrates this effect. I had never quite thought about it, but realised it was of course always true: the mirror is at half the distance specified in the reflection. Then I read this post linked from the original, which reviewed an article by Lawson et al (2007) describing how people mis........ Read more »
Lawson, R., Bertamini, M., & Liu, D. (2007) Overestimation of the projected size of objects on the surface of mirrors and windows. Journal of Experimental Psychology: Human Perception and Performance, 33(5), 1027-1044. DOI: 10.1037/0096-15126.96.36.1997
As many of you know, I generally avoid writing about non open access publications here. But occasionally I make exceptions. And I am making one today. There is a wicked cool paper out in Nature today. Entitled "Hydrogen is an energy source for hydrothermal vent symbioses" comes from Nicole Dubilier, Jillian Petersen and others. It is about my favorite ecosystem(s) on the planet - hydrothermal vents. I became interested in these vents in 1989 when I met Colleen Cavan........ Read more »
Petersen JM, Zielinski FU, Pape T, Seifert R, Moraru C, Amann R, Hourdez S, Girguis PR, Wankel SD, Barbe V.... (2011) Hydrogen is an energy source for hydrothermal vent symbioses. Nature, 476(7359), 176-80. PMID: 21833083
There is a very interesting new paper that just came online in the Archives of Pathology: Rapidly Progressive, Fatal, Inhalation Anthrax-Like Infection in a Human: Case Report, Pathogen Genome Sequencing, Pathology, and Coordinated Response
I was alerted to the paper by Eileen Choffnes of the National Academy of Sciences Institute of Medicine Forum on Microbial Threats (which I am a member of). In the paper, James Musser, Angela Wright and colleagues, the authors discuss the use of genome........ Read more »
Wright AM, Beres SB, Consamus EN, Long SW, Flores AR, Barrios R, Richter GS, Oh SY, Garufi G, Maier H.... (2011) Rapidly Progressive, Fatal, Inhalation Anthraxlike Infection in a Human: Case Report, Pathogen Genome Sequencing, Pathology, and Coordinated Response. Archives of pathology . PMID: 21827220
A few days ago I became aware of the publication of a cool new paper: "Defining seasonal marine microbial community dynamics" by Jack A. Gilbert, Joshua A Steele, J Gregory Caporaso, Lars Steinbrück, Jens Reeder, Ben Temperton, Susan Huse, Alice C McHardy, Rob Knight, Ian Joint, Paul Somerfield, Jed A Fuhrman and Dawn Field. The paper was published in the ISME Journal and is freely available using the ISME Open option.
If you want to know more about Jack (in case you don't k........ Read more »
Gilbert JA, Steele JA, Caporaso JG, Steinbrück L, Reeder J, Temperton B, Huse S, McHardy AC, Knight R, Joint I.... (2011) Defining seasonal marine microbial community dynamics. The ISME journal. PMID: 21850055
A critical look at a CAM paper... Read more »
Panda AK, & Doddanagali SR. (2011) Clinical efficacy of herbal Padmapatradi yoga in bronchial asthma (Tamaka Swasa). Journal of Ayurveda and integrative medicine, 2(2), 85-90. PMID: 21760694
Does knowledge of brain function alter brain function? The development of psychology is based on this premise, either implicitly or explicitly. Where psychologists focus on behaviour as the main measure of interest, linking behaviour directly to brain function has been one of the popular mysteries and goals of neuroscience throughout the last few decades. ... Read more »
Li J, Delgado MR, & Phelps EA. (2011) How instructed knowledge modulates the neural systems of reward learning. Proceedings of the National Academy of Sciences of the United States of America, 108(1), 55-60. PMID: 21173266
Moradi F, Buračas GT, & Buxton RB. (2011) Attention strongly increases oxygen metabolic response to stimulus in primary visual cortex. NeuroImage. PMID: 21839179
Watkins S, Shams L, Josephs O, & Rees G. (2007) Activity in human V1 follows multisensory perception. NeuroImage, 37(2), 572-8. PMID: 17604652
The exact role that dopamine plays in learning remains controversial; some think it acts as a prediction error signal, while Berrdige et al believe that dopamine codes for incentive salience.
A recent paper throws some light on the issue. It uses a simple Pavlovian conditioning paradigm. To recap, US and CS are paired and after some [...]Rating: 0.0/10 (0 votes cast)... Read more »
Flagel, S., Clark, J., Robinson, T., Mayo, L., Czuj, A., Willuhn, I., Akers, C., Clinton, S., Phillips, P., & Akil, H. (2010) A selective role for dopamine in stimulus–reward learning. Nature, 469(7328), 53-57. DOI: 10.1038/nature09588
After a period of heavy use, hard disks tend to get 'fragmented'. Data gets written all over random parts of the disk, and it gets inefficient to keep track of it all.
That's why you need to run a defragmentation program occasionally. Ideally, you do this overnight, while you're asleep, so it doesn't stop you from using the computer.
A new paper from some Stanford neuroscientists argues that the function of sleep is to reorganize neural connections - a bit like a disk defrag for the brain - a........ Read more »
Wang G, Grone B, Colas D, Appelbaum L, & Mourrain P. (2011) Synaptic plasticity in sleep: learning, homeostasis and disease. Trends in neurosciences. PMID: 21840068
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