Post List

  • April 28, 2010
  • 09:10 AM

Tip of the Week: International Cancer Genome Consortium

by Mary in OpenHelix

So, remember that tidal wave of data we were going to get from the human genome project?  Yeah.  That was a puddle compared to what’s coming your way now. For this week’s tip of the week I will introduce the very ambitious big data project from the International Cancer Genome Consortium (ICGC).  In addition, you’ll [...]... Read more »

Hudson (Chairperson), T., Anderson, W., Aretz, A., Barker, A., Bell, C., Bernabé, R., Bhan, M., Calvo, F., Eerola, I., Gerhard, D.... (2010) International network of cancer genome projects. Nature, 464(7291), 993-998. DOI: 10.1038/nature08987  

  • April 28, 2010
  • 09:00 AM

Peer-to-peer data storage

by David Bradley in Sciencetext

Whenever anyone mentions P2P file systems, the first thought that pops into the n00bs head is probably – piracy – and an image of teens downloading free copies of the latest young person’s popular music tracks from teh interwebs using an illicit file sharing system. Of course, Bit Torrent and other related systems can be [...]Post from: David Bradley's Sciencetext Tech TalkPeer-to-peer data storage
... Read more »

Yu-Wei Chan, Tsung-Hsuan Ho, Po-Chi Shih, & Yeh-Ching Chung. (2010) Malugo: A peer-to-peer storage system. Int. J. Ad Hoc and Ubiquitous Computing, 5(4), 209-218. info:/

  • April 28, 2010
  • 09:00 AM

Lifelong learning online is about connecting people

by sciencebase in Sciencebase Science Blog

Individuals now have the autonomy to make their own learning choices and in recent years there has been an emphasis on the “self made learner”, especially in adult education and ongoing professional development. As such, online communities and other so-called web 2.0 tools have come to the fore as potentially useful for educators and students [...]Lifelong learning online is about connecting people is a post from: Sciencebase Science Blog
... Read more »

Cristina Costa. (2010) Lifelong learning in Web 2.0 environments. Int. J. Technology Enhanced Learning, 2(3), 275-284. info:/

  • April 28, 2010
  • 09:00 AM

Tilting the three-way tango - disease as a loss of diversity

by Alistair Dove in Deep Type Flow

Disease is a funny old thing.  We're taught from very early on that disease agents are "bad" and that, by contrast, the infected are somehow poor and unfortunate victims of nasty evil bugs.  This is clearly a cultural bias, wherein we project our own concerns about getting sick onto all other animals; there's no real reason to think that a bacterium or virus has any less right to be here or any ... Read more »

  • April 28, 2010
  • 08:48 AM

Maternal infection during pregnancy and autism: The “flu hypothesis” revisited.

by Nestor Lopez-Duran PhD in Child-Psych

The last issue of the Journal of Autism and Developmental Disorders included one of the largest examinations of the association between maternal infection during pregnancy and risk for autism. The study was conducted in the Denmark where researchers examined the maternal infection rates during pregnancy and autism diagnoses for all children born in Denmark between [...]... Read more »

Atladóttir, H., Thorsen, P., Østergaard, L., Schendel, D., Lemcke, S., Abdallah, M., & Parner, E. (2010) Maternal Infection Requiring Hospitalization During Pregnancy and Autism Spectrum Disorders. Journal of Autism and Developmental Disorders. DOI: 10.1007/s10803-010-1006-y  

  • April 28, 2010
  • 08:14 AM

Who Moved My Garden? Spatial Learning in the Octopus

by Jason Goldman in The Thoughtful Animal

Say you're visiting Los Angeles and you have a sudden craving for Chinese food. Since you are only visiting, you might not be aware that nothing is open past, like, 10pm (not even coffee houses), but you get in your rental car and go driving around in search of your Chinese feast anyway. You try hitting up Panda Express, but no such luck. Of course they're closed. You try the neighborhood Chinese restaurant: closed as well. You get back in the car, and think to yourself "maybe the OTHER Panda Ex........ Read more »

  • April 28, 2010
  • 08:00 AM

How much are the ecosystems of New Jersey worth to society?

by Rob Goldstein in Conservation Maven

... Read more »

  • April 28, 2010
  • 08:00 AM

The Brain Rejects Inequality

by Shaheen Lakhan in Brain Blogger

The human brain likes balance. Not simply biological and physiological homeostasis that maintains the proper functioning of the brain, but emotional, social and psychological balance. Notably, the human brain dislikes inequality when it comes to money, and rejects it at all costs, according to new research in the journal Nature.
Behavioral and anthropological evidence show that [...]... Read more »

Guroglu, B., van den Bos, W., Rombouts, S., & Crone, E. (2010) Unfair? It depends: Neural correlates of fairness in social context. Social Cognitive and Affective Neuroscience. DOI: 10.1093/scan/nsq013  

Smith, D., Hayden, B., Truong, T., Song, A., Platt, M., & Huettel, S. (2010) Distinct Value Signals in Anterior and Posterior Ventromedial Prefrontal Cortex. Journal of Neuroscience, 30(7), 2490-2495. DOI: 10.1523/JNEUROSCI.3319-09.2010  

Tricomi, E., Rangel, A., Camerer, C., & O’Doherty, J. (2010) Neural evidence for inequality-averse social preferences. Nature, 463(7284), 1089-1091. DOI: 10.1038/nature08785  

Yamagishi, T., Horita, Y., Takagishi, H., Shinada, M., Tanida, S., & Cook, K. (2009) The private rejection of unfair offers and emotional commitment. Proceedings of the National Academy of Sciences, 106(28), 11520-11523. DOI: 10.1073/pnas.0900636106  

  • April 28, 2010
  • 06:00 AM

Ethnic Variation in Obesity Risk

by Dr. Arya Sharma in Dr. Sharma's Obesity Notes

In this paper, we looked at the relationship between body weight (BMI), adipokines, and insulin resistance in 1,176 South Asian, Chinese, Aboriginal, and European Canadians in the SHARE study (Study of Health Assessment and Risk in Ethnic groups).... Read more »

  • April 28, 2010
  • 05:00 AM

Study finds stream restoration has little impact on benthic invertebrate community

by Rob Goldstein in Conservation Maven

A new study looks at 26 restored river sites across Europe and finds little evidence that these projects have impacted the benthic invertebrate community - i.e. the worms, crustaceans, and other organisms that dwell on the bottom of freshwater systems...... Read more »

  • April 28, 2010
  • 03:17 AM

What are breeders selecting for?

by Jeremy in Agricultural Biodiversity Weblog

One of the arguments in the organic-can-feed-the-world oh-no-it-can’t ding dong is about the total yield of organic versus non-organic. Organic yields are generally lower. One reason might be that, with a few exceptions, mainstream commercial and public-good breeders do not regard organic agriculture as a market worth serving. The increase in yield of, say, [...]... Read more »

  • April 28, 2010
  • 01:54 AM

A Paper on Pain and the Power of Negative Data

by Evil Monkey in Neurotopia

So Sci was scrounging around the internet for blog topics recently. Every time she does this, she is of course completely overwhelmed by the piles of cool and bloggable science out there (seriously, I've got like 20 topics for the next week, of course not all will make it). But she's also surprised to see some familiar faces. A lot of times it's a familiar face related to her field and the stuff she's been recently interested in (for example, Yavin Shaham just wrote an interesting editorial o........ Read more »

Sakshi Puri, Zen Faulkes. (2010) Do Decapod Crustaceans Have Nociceptors for Extreme pH?. PLoS ONE, 5(4). info:/10.1371/journal.pone.0010244

  • April 28, 2010
  • 01:28 AM

Philip Campbell on Science Facts and Frictions

by Duncan Hull in O'Really?

As part of the Gates Distinguished Lecture Series editor Philip Campbell is giving a public lecture at 6.30pm tonight titled Science – facts and frictions at Emmanuel College, Cambridge. The abstract and text below reproduced from ‘Climategate’, MMR vaccine, GM crops, stem cells – these are examples of public debates in which science and [...]... Read more »

Philip Campbell. (1995) Postscript from a new hand. Nature, 378(6558), 649-649. DOI: 10.1038/378649b0  

  • April 27, 2010
  • 10:39 PM

Do metamorphic proteins mediate evolutionary structural transitions?

by Michael Clarkson in Conformational Flux

On several previous occasions on this blog I've discussed proteins that undergo significant changes in structure without drastic changes in their primary sequence or solution conditions. In some cases, a few mutations can take a protein to a novel fold, as with Philip Bryan's protein G work. In others, closely related sequences within a whole family populate different kinds of folds, as Matt Cordes illustrated for the case of Cro proteins. In addition, there are some cases such as lymphotactin, ........ Read more »

Yadid, I., Kirshenbaum, N., Sharon, M., Dym, O., & Tawfik, D. (2010) Metamorphic proteins mediate evolutionary transitions of structure. Proceedings of the National Academy of Sciences, 107(16), 7287-7292. DOI: 10.1073/pnas.0912616107  

  • April 27, 2010
  • 10:33 PM

Tournament marlins get bigger?

by Southern Fried Scientist in Southern Fried Science

This week’s ResearchBlogCast featured the paper “Decline in top predator body size and changing climate alter trophic structure in an oceanic ecosystem”, originally discussed at Fish Schooled (Prey populations explode as predators get smaller). In both the podcast and the blogpost, the authors argue that prey abundance booms despite predator biomass remaining constant [...]... Read more »

Shackell, N., Frank, K., Fisher, J., Petrie, B., & Leggett, W. (2009) Decline in top predator body size and changing climate alter trophic structure in an oceanic ecosystem. Proceedings of the Royal Society B: Biological Sciences, 277(1686), 1353-1360. DOI: 10.1098/rspb.2009.1020  

Jorgensen, C., Enberg, K., Dunlop, E., Arlinghaus, R., Boukal, D., Brander, K., Ernande, B., Gardmark, A., Johnston, F., Matsumura, S.... (2007) Ecology: Managing Evolving Fish Stocks. Science, 318(5854), 1247-1248. DOI: 10.1126/science.1148089  

  • April 27, 2010
  • 10:09 PM

Inflammation and Life Span Differences Between Species

by Reason in Fight Aging!

A number of researchers are very interested in exploring differences in life span between species as a way to better understand the biology of aging; this is another branch of the mainstream interest in uncovering ways to manipulate genes and metabolism to slow aging. Amongst these scientists is Joao de Magalhaes, who runs the excellent websites, including the GenAge and AnAge databases. You should certainly browse through the materials there if you haven't already done so. You m........ Read more »

  • April 27, 2010
  • 09:31 PM

Diagnostic accuracy of confrontation visual field tests

by Robert Badgett in ClinDx

If no tools to aid examination are available, finger comparison is the most sensitive test and finger counting is the more specific test. ... Read more »

Kerr NM, Chew SS, Eady EK, Gamble GD, & Danesh-Meyer HV. (2010) Diagnostic accuracy of confrontation visual field tests. Neurology, 74(15), 1184-90. PMID: 20385890  

  • April 27, 2010
  • 07:04 PM

The specialization of novel genes

by Leonardo Martins in bioMCMC

Recently a paper about the software MANTiS called my attention, and I’ve been trying to write about it for a while. This announcement at the EvolDir list seemed like the perfect opportunity. I must warn you though that I’ve never used the software and I don’t have any intimacy with the underlying databases, but the [...]... Read more »

Milinkovitch, M., Helaers, R., & Tzika, A. (2009) Historical Constraints on Vertebrate Genome Evolution. Genome Biology and Evolution, 13-18. DOI: 10.1093/gbe/evp052  

Tzika, A., Helaers, R., Van de Peer, Y., & Milinkovitch, M. (2007) MANTIS: a phylogenetic framework for multi-species genome comparisons. Bioinformatics, 24(2), 151-157. DOI: 10.1093/bioinformatics/btm567  

  • April 27, 2010
  • 07:01 PM

R-Rated Movies Aren't Bad for Your Kids...R They?

by Neuropsych15 in The MacGuffin

In the May issue of the Journal of Studies on Alcohol and Drugs is an article titled "Parental R-Rated Movie Restriction and Early-Onset Alcohol Use." (1) Without reading the study, one can guess the reported result : the more R-rated movies that youths watch, the higher the frequency of early-onset alcohol use. This study was funded by the National Cancer Institute and National Institute on Alcohol Abuse and Alcoholism. Remember what the Last Psychiatrist says: What do researcher........ Read more »

Tanski SE, Cin SD, Stoolmiller M, & Sargent JD. (2010) Parental R-rated movie restriction and early-onset alcohol use. Journal of studies on alcohol and drugs, 71(3), 452-9. PMID: 20409440  

  • April 27, 2010
  • 05:12 PM

Does Viagra Improve Relationships?

by eHarmony Labs in eHarmony Labs Blog

Can this little blue pill make you more satisfied in your relationship? The answer is not as straightforward as you might think. Find out more.... Read more »

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