Post List

  • January 22, 2011
  • 04:38 PM
  • 1,062 views

Weekend Short Stories

by Matthew DiLeo in The Scientist Gardener

Some pretty cool links for your weekend:

Jurassic Park beer:

Fossil Fuels Brewing Co. makes beer with an Eocene-era yeast, formerly encased in a 45 million year old chunk of amber! Incredible, but apparently true. Viable Bacillus spores were discovered first in 25-40 million year old amber by Raul Cano (these spores are so tough you can't kill them with an autoclave). He then founded a startup (Ambergene) with the hopes of discovering ancient antibiotics (this was back during the natural ........ Read more »

  • January 22, 2011
  • 04:22 PM
  • 1,703 views

Did Intestinal parasites and poor hygiene protect us from autoimmune diseases?

by ABK in Environment and Health

Autoimmune diseases are troubling, and often frustrating and painful for health care practitioners and patients. As far as I know, celiac disease is the only autoimmune disorder with a specific and identified trigger: the protein gluten. It has also been pointed out that the incidence of Celiac Disease, the formal name for gluten-triggered autoimmune reactions in the bowel, appears to have been increasing. Some have claimed that humans are not adapted to consumption of plant proteins like glu........ Read more »

  • January 22, 2011
  • 01:50 PM
  • 701 views

New Year--New Fossils--New Papers!!!

by Paleochick in Paleochick's Digs

Dearest readers,
I hope all of you had a warm and happy holiday season! I’ve missed you! It...... Read more »

Lu, J., Unwin, D., Deeming, D., Jin, X., Liu, Y., & Ji, Q. (2011) An Egg-Adult Association, Gender, and Reproduction in Pterosaurs. Science, 331(6015), 321-324. DOI: 10.1126/science.1197323  

  • January 22, 2011
  • 12:46 PM
  • 1,066 views

When "Healthy Brains" Aren't

by Neuroskeptic in Neuroskeptic

There's a lot of talk, much of it rather speculative, about "neuroethics" nowadays.But there's one all too real ethical dilemma, a direct consequence of modern neuroscience, that gets very little attention. This is the problem of incidental findings on MRI scans.An "incidental finding" is when you scan someone's brain for research purposes, and, unexpectedly, notice that something looks wrong with it. This is surprisingly common: estimates range from 2–8% of the general population. It will hap........ Read more »

Cramer SC, Wu J, Hanson JA, Nouri S, Karnani D, Chuang TM, & Le V. (2011) A system for addressing incidental findings in neuroimaging research. NeuroImage. PMID: 21224007  

  • January 22, 2011
  • 12:38 PM
  • 769 views

Transparency

by Janet Kwasniak in Thoughts on thoughts


Thomas Metzinger wrote an outline of his book, ‘Being No One’, which puts his theory of consciousness in a very brief, compact form. He puts forward a list of constraints that any system must have to be conscious. The first three constrains gives a simple form of consciousness which he then elaborates with further constrains. [...]... Read more »

Thomas Metzinger. (2005) Precis of - Being No One. Psyche - An Interdisciplinary Journal of Research on Consciousness, 11(5). info:/

  • January 22, 2011
  • 10:10 AM
  • 1,370 views

Kinky evolution: did we evolve from PVC?

by Gemma Atkinson in Protein evolution and other musings

PVC may have played a big part in our evolution... But, no I'm not talking about polyvinyl chloride (sorry to dissapoint!), I'm talking about the Planctomycetes, Verrucomicrobia, Chlamydiae (PVC) bacterial superphylum. And I'm talking waaaay back, when the Chlamydiae were much more innocent and hadn't got into that whole sexually transmitted disease scene.In a Science article, Devos and Reynaud discuss the possibility that that The PVC bugs, which appear to be a monophyletic group forming their ........ Read more »

Devos, D., & Reynaud, E. (2010) Intermediate Steps. Science, 330(6008), 1187-1188. DOI: 10.1126/science.1196720  

Fuerst JA, & Webb RI. (1991) Membrane-bounded nucleoid in the eubacterium Gemmatata obscuriglobus. Proceedings of the National Academy of Sciences of the United States of America, 88(18), 8184-8. PMID: 11607213  

Lonhienne, T., Sagulenko, E., Webb, R., Lee, K., Franke, J., Devos, D., Nouwens, A., Carroll, B., & Fuerst, J. (2010) From the Cover: Endocytosis-like protein uptake in the bacterium Gemmata obscuriglobus. Proceedings of the National Academy of Sciences, 107(29), 12883-12888. DOI: 10.1073/pnas.1001085107  

  • January 22, 2011
  • 09:09 AM
  • 1,299 views

The causes you “like” on Facebook may actually matter

by Janelle Ward in Janelle's research blog

The book manuscript I’m currently working on for Hampton Press involves an updated section on social media. When I started my dissertation research in 2003, websites were all the rage – and the only rage. Now, organizations of all types … Continue reading →... Read more »

  • January 22, 2011
  • 09:00 AM
  • 2,467 views

Can’t sleep? Why taking the Blue Pill is Best! (Unless you’re an Italian man)

by Stuart Farrimond in Dr Stu's Science Blog

Insomnia is something all of us struggle with from time to time. Not being able to get off to sleep is perhaps one of the most frustrating and loathsome things in the world (second only to an itchy back).

Many of us resort to herbal or medical remedies. If you had to choose one, which would you go for? Did you realise though that the colour of your remedy has an effect!? Read on to find out why blue is best…... Read more »

  • January 22, 2011
  • 07:56 AM
  • 2,110 views

living things and slightly expanding universes

by Greg Fish in weird things

Today, we’re going back to my old frienemy, the arXiv blog. Even though I tend to beat up on it quite a bit, the preprint archive does have some interesting papers, even if the only interesting part about them is shredding them for a skeptical post. Then again, this sort of constant criticism of scientific [...]... Read more »

Hugo Martel, Paul R. Shapiro, & Steven Weinberg. (1997) Likely Values of the Cosmological Constant. Astrophys.J. 492 (1998) 29. arXiv: astro-ph/9701099v1

Don N. Page. (2011) Evidence Against Fine Tuning for Life. n/a. arXiv: 1101.2444v1

  • January 21, 2011
  • 09:06 PM
  • 806 views

Smoking & Alcohol 'to blame for majority of gender gap in deaths'

by crabsallover in Science of Healthy Long Life

reposted from: http://info.cancerresearchuk.org/news/archive/cancernews/2011-01-19-Smoking-to-blame-for-majority-of-gender-gap-in-deaths-?rss=truecrabsallover highlights, key points, comments / links.Wednesday 19 January 2011Smoking accounts for up to 60 per cent of the gender gap in death rates across Europe, according to a new study by scientists at the MRC/CSO Social and Public Health Sciences Unit in Glasgow.The study authors set out to investigate death ra........ Read more »

  • January 21, 2011
  • 08:41 PM
  • 3,479 views

The Universe and Life is asymmetric: Chirality

by The Astronomist in The Astronomist.

The shadow of symmetry haunts physics. Symmetry is invoked to understand nature concisely, but broken symmetry is invoked to understand nature completely. Physics is filled with examples of shattered symmetries: there is more matter than antimatter, neutrinos only come in the left handed spin flavor, and quantum processes break symmetries constantly, but nature also violates symmetry in chemistry and biology in a very clever manner. Chemistry and biology are subjects I do no normally touch ........ Read more »

Robert N. Compton, Richard M. Pagni, & Volume 48, 2002, Pages 219-261. (2002) The chirality of biomolecules. Advances In Atomic, Molecular, and Optical Physics, 219-261. info:/

  • January 21, 2011
  • 06:37 PM
  • 785 views

Genomic Imprinting IV: Escalation Between Loci

by Jon Wilkins in Lost in Transcription

So, in the previous installment, we introduced the "Loudest Voice Prevails" principle, which describes the evolutionarily stable pattern of gene expression at an imprinted locus where there is an intragenomic conflict over the total level of gene expression. Basically, the allele that favors lower expression becomes transcriptionally silenced. Expression from the other allele (the "louder" voice) evolves to the level that maximizes its inclusive fitness. In this sense, the active allele at an im........ Read more »

Wilkins, J., & Haig, D. (2001) Genomic imprinting of two antagonistic loci. Proceedings of the Royal Society B: Biological Sciences, 268(1479), 1861-1867. DOI: 10.1098/rspb.2001.1651  

  • January 21, 2011
  • 06:25 PM
  • 1,759 views

When & Were Grapes Domesticated

by Kambiz Kamrani in Anthropology.net

I got some archaeobotany for you to start your weekend off right with — a new open access study in PNAS announces a genome wide association of 8,000 years of grape domestication, spanning the Eastern Caucasus to Western Europe. Lead … Continue reading →... Read more »

Myles, S., Boyko, A., Owens, C., Brown, P., Grassi, F., Aradhya, M., Prins, B., Reynolds, A., Chia, J., Ware, D.... (2011) Genetic structure and domestication history of the grape. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1009363108  

  • January 21, 2011
  • 06:13 PM
  • 3,123 views

Halitosis - Your mouth smells like arse

by James Byrne in Disease Prone

Sometimes I'm going to write about rare cancers or blood diseases and sometimes I’m going to write about bad breath. That’s just the way I roll.

Halitosis literally means “condition of the breath” and has many causes and just as many home remedies. Original therapies (and by original I mean 1550 BC) like heavily herb infused wines didn’t remove the bad breath but like mints and other modern treatments they just attempted to cover the bad smell with something more pleasant.




Halitos........ Read more »

Suarez FL, Furne JK, Springfield J, & Levitt MD. (2000) Morning breath odor: influence of treatments on sulfur gases. Journal of dental research, 79(10), 1773-7. PMID: 11077993  

  • January 21, 2011
  • 06:10 PM
  • 1,178 views

Agonist, partial agonist, irreversible agonist-bound and GPCR active state crystal structures

by Peter Nollert in Emerald BioStructures Blog

Wow, the new year is off to a great start in GPCR structural biology: Rasmussen SG, Choi HJ, Fung JJ, Pardon E, Casarosa P, Chae PS, Devree BT, Rosenbaum DM, Thian FS, Kobilka TS, Schnapp A, Konetzki I, Sunahara RK, Gellman SH, Pautsch A, Steyaert J, Weis WI, & Kobilka BK (2011). Structure of a [...]... Read more »

Rasmussen SG, Choi HJ, Fung JJ, Pardon E, Casarosa P, Chae PS, Devree BT, Rosenbaum DM, Thian FS, Kobilka TS.... (2011) Structure of a nanobody-stabilized active state of the β(2) adrenoceptor. Nature, 469(7329), 175-80. PMID: 21228869  

Rosenbaum DM, Zhang C, Lyons JA, Holl R, Aragao D, Arlow DH, Rasmussen SG, Choi HJ, Devree BT, Sunahara RK.... (2011) Structure and function of an irreversible agonist-β(2) adrenoceptor complex. Nature, 469(7329), 236-40. PMID: 21228876  

Warne T, Moukhametzianov R, Baker JG, Nehmé R, Edwards PC, Leslie AG, Schertler GF, & Tate CG. (2011) The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor. Nature, 469(7329), 241-4. PMID: 21228877  

  • January 21, 2011
  • 06:08 PM
  • 1,324 views

Personalizing Addiction Medicine

by Dirk Hanson in Addiction Inbox


Gene variants make anti-craving drugs a hit-or-miss affair.

Rather than taking on another broad hunt for the genes controlling the expression of alcoholism, noted addiction researcher Dr. Bankole Johnson and co-workers at the Department of Psychiatry and Neurobehavioral Sciences at the University of Virginia took a different tack. The researchers focused, instead, on investigating whether genetic variations among alcoholics might affect their responses to a specific anti-craving medication.

T........ Read more »

Johnson, B., Ait-Daoud, N., Seneviratne, C., Roache, J., Javors, M., Wang, X., Liu, L., Penberthy, J., DiClemente, C., & Li, M. (2011) Pharmacogenetic Approach at the Serotonin Transporter Gene as a Method of Reducing the Severity of Alcohol Drinking. American Journal of Psychiatry. DOI: 10.1176/appi.ajp.2010.10050755  

  • January 21, 2011
  • 04:49 PM
  • 1,080 views

dbSNP, or is it?

by Todd Smith in finchtalk

dbSNP is NCBI’s catalog of DNA variation. While the SNP in the name implies a focus on Single Nucleotide Polymorphisms, dbSNP is far more comprehensive and includes length variants, mutations, and a plethora of annotations that characterize over 75...

[[ This is a content summary only. Visit my website for full links, other content, and more! ]]... Read more »

  • January 21, 2011
  • 04:10 PM
  • 1,479 views

How many omega-3s does your dinner have?

by Melinda Moyer in Body Politic

As I approach my third trimester, I’m becoming a bit of an omega-3 fiend. The unsaturated fatty acids have not only been tied to lower heart disease risk in adults, but they have also been shown to boost fetal brain development, especially when consumed in the final few months of pregnancy. Given that I’m not much of a cold water fish fan—the thought of chewing a mouthful of sardines makes me want to gag—I’ve been looking into how else to get them, and what I’ve uncov........ Read more »

  • January 21, 2011
  • 03:44 PM
  • 1,596 views

Out With The Scientists, In With The Quacks (and religious zealots)

by Neurobonkers in Neurobonkers

The Government announced this week the list... Read more »

Rolles S. (2010) An alternative to the war on drugs. BMJ (Clinical research ed.). PMID: 20627976  

  • January 21, 2011
  • 03:31 PM
  • 1,006 views

Music and the Brain: Emotion

by Luc Duval in The Pedagogic Verses

As a preface to a post about 2011 research by many of the same scientists, this post discusses previous work on music and the emotion that led to the recently published dopamine study.... Read more »

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