With Copenhagen on the horizon, is it time to check over the physics and chemistry behind the climate change debate? SciScoop has spoken to several scientists recently who would say so, some of whom consider the climate change debate nothing more than a hell-on-earth scenario to give governments a taxation stick with which to beat [...]... Read more »
Willett, K., Gillett, N., Jones, P., & Thorne, P. (2007) Attribution of observed surface humidity changes to human influence. Nature, 449(7163), 710-712. DOI: 10.1038/nature06207
If you don’t have to worry about reproduction, life gets a little simpler. You have to worry about eating. You have to worry about being eaten. And with that, you’re pretty close to done.
Aspidoscelis uniparens is a parthenogenetic whiptail lizard (formerly Cnemidophorus uniparens), and Eifler and colleagues tested how they allocated their time under threat. To do they, they made six large enclosures (225 square meters) and put in six of these small lizards in. In half of these, the........ Read more »
Eifler, D., Eifler, M., & Harris, B. (2007) Foraging under the risk of predation in desert grassland whiptail lizards (Aspidoscelis uniparens). Journal of Ethology, 26(2), 219-223. DOI: 10.1007/s10164-007-0053-0
The Obama administration provided $1.1 billion for health care comparative effectiveness research in the American Recovery and Reinvestment Act (ARRA). Following this, the Institute of Medicine (IOM) delivered a report in June with comparative effectiveness research priorities (downloadable file). However,...... Read more »
Baucus, M. (2009) Doctors, Patients, and the Need for Health Care Reform. New England Journal of Medicine, 361(19), 1817-1819. DOI: 10.1056/NEJMp0910001
Sox HC, & Greenfield S. (2009) Comparative effectiveness research: a report from the Institute of Medicine. Annals of internal medicine, 151(3), 203-5. PMID: 19567618
Schwartz, L., & Woloshin, S. (2009) Lost in Transmission -- FDA Drug Information That Never Reaches Clinicians. New England Journal of Medicine, 361(18), 1717-1720. DOI: 10.1056/NEJMp0907708
The number of influenza cases this year seems to have peaked and started to drop in the last few weeks, according to both the CDC surveillance data and Google Flu Trends (which updates more in real-time). Does that mean swine-origin influenza virus is gone for good? We don’t know, of course, but I was struck [...]... Read more »
D. A. Henderson, Brooke Courtney, Thomas V. Inglesby, Eric Toner, & Jennifer B. Nuzzo. (2009) Public Health and Medical Responses to the 1957-58 Influenza Pandemic. Biosecurity and Bioterrorism, 7(3), 1-9. info:/
Lui, K., & Kendal, A. (1987) Impact of influenza epidemics on mortality in the United States from October 1972 to May 1985. American Journal of Public Health, 77(6), 712-716. DOI: 10.2105/AJPH.77.6.712
A new study examining the outcomes of two different rehabilitation programs following anterior cruciate ligament (ACL) reconstruction was recently published in AJSM. The authors, from Oslo University in Norway, compared the outcomes from two groups of 74 patients (mean age 28 years old) after 6 months of rehabilitation. Group one performed a neuromuscular exercise program consisting of what the authors defined as balance exercises, dynamic joint stability exercises, plyometric exercise........ Read more »
Risberg MA, & Holm I. (2009) The long-term effect of 2 postoperative rehabilitation programs after anterior cruciate ligament reconstruction: a randomized controlled clinical trial with 2 years of follow-up. The American journal of sports medicine, 37(10), 1958-66. PMID: 19556470
Men and women with more testosterone like to be in charge. Indeed, they can find it stressful and uncomfortable when denied the status that they crave. Similarly, people low in testosterone find it uncomfortable to be placed in positions of authority. An intriguing new study has built on these earlier findings, showing a mismatch between testosterone-level and status can have an effect on group functioning. Groups made up of people whose status in the group doesn't match their testosterone level........ Read more »
Zyphur, M., Narayanan, J., Koh, G., & Koh, D. (2009) Testosterone–status mismatch lowers collective efficacy in groups: Evidence from a slope-as-predictor multilevel structural equation model. Organizational Behavior and Human Decision Processes, 110(2), 70-79. DOI: 10.1016/j.obhdp.2009.05.004
When feeling down good music can cheer you up. But when depressed, I mean clinically depressed, can you enjoy music? How is music enjoyment processed by the brain and how is this influenced by depression?
All participants of this study enjoyed their favorite music more than the neutral music and depressed patients didn’t differ from the [...]
Related posts:The Neurobiology of Empathy through Pain Research There are patients with congenital insensitivity to pain (CIP) this...Neuroscienc........ Read more »
Osuch, E., Bluhm, R., Williamson, P., Théberge, J., Densmore, M., & Neufeld, R. (2009) Brain activation to favorite music in healthy controls and depressed patients. NeuroReport, 20(13), 1204-1208. DOI: 10.1097/WNR.0b013e32832f4da3
Can chronic pain be a force that shapes how we go about responding to challenges within our environments?
Does chronic pain influence how we feel emotionally about daily activities that contribute to overall goals, and perhaps negatively bias the way we think about the process of setting and achieving goals?
I’ve already concluded that having [...]... Read more »
Hamilton, N., Karoly, P., & Kitzman, H. (2004) Self-Regulation and Chronic Pain:The Role of Emotion. Cognitive Therapy and Research, 28(5), 559-576. DOI: 10.1023/B:COTR.0000045565.88145.76
Nature Genetics on Friday released the paper from Jay Shendure, Debra Nickerson and colleagues which used targeted sequencing to identify the damaged gene in a rare Mendelian disorder, Miller syndrome. The work had been presented at least in part at recent meetings, but now all of us can digest it in entirety.The impressive economy of this paper is that they targeted (using Agilent chips) less than 30Mb of the human genome, which is less than 1%. They also worked with very few samples; only ab........ Read more »
Sarah B. Ng, Kati J. Buckingham, Choli Lee, Abigail W. Bigham, Holly K. Tabor, Karin M. Dent, Chad D. Huff, Paul T. Shannon, Ethylin Wang Jabs, Deborah A. Nickerson.... (2009) Exome sequencing identifies the cause of a mendelian disorder. Nature genetics. info:/doi:10.1038/ng.499
Climate modeling is hard. The Earth’s climate system is complex, with infinite interactions and feedbacks that interact across scales. There is often uncertainty, and a result the models are inherently imprecise.Nonetheless, they’re a powerful tool, and they get better every day. Scaling down these models is critical to providing a better prediction of future climate and rainfall patterns. And a recent study in Environment, Development and Sustainability does exactly this to show wha........ Read more »
Ibarrarán, M., Malone, E., & Brenkert, A. (2009) Climate change vulnerability and resilience: current status and trends for Mexico. Environment, Development and Sustainability. DOI: 10.1007/s10668-009-9201-8
The other day I was proofreading the paper of a colleague when this paper in the reference list caught my attention. Not familiar with retail supply chains, here was a chance to learn something new…so I thought, and so I did. However, I’m not sure I follow the authors in their risk categorization: supply, demand and “miscellanous” risk? What is this “miscellanous” risk?
... Read more »
Oke, A., & Gopalakrishnan, M. (2009) Managing disruptions in supply chains: A case study of a retail supply chain. International Journal of Production Economics, 118(1), 168-174. DOI: 10.1016/j.ijpe.2008.08.045
Wildlife farming in Southeast Asia has emerged as a potential conservation tool for rare and threatened species that are regularly poached in the wild primarily for upscale consumers in urban markets. But a new study finds that it has unintended negative consequences...read more... Read more »
Drury, R. (2009) Reducing urban demand for wild animals in Vietnam: examining the potential of wildlife farming as a conservation tool. Conservation Letters. DOI: 10.1111/j.1755-263X.2009.00078.x
New materials to make batteries with might actually rival petrol for energy storage capacity.... Read more »
Bacterial (and archaeal) signalling systems are remarkably similar to eukaryotic ones. As well as the typical and well described two-component signalling systems (a histadine-kinase sensor which senses a signal and passes this on to a response-regulator) bacteria also contain multi-component systems, for both inter- and intra-cellular signalling.All cells constantly monitor their external and internal environment in order to effectively exploit their surroundings. Bacteria are no different, and ........ Read more »
Galperin MY. (2005) A census of membrane-bound and intracellular signal transduction proteins in bacteria: bacterial IQ, extroverts and introverts. BMC microbiology, 35. PMID: 15955239
Actually, this is only good news
for coffee drinkers who also have
late-stage hepatitis C. A recent study in Hepatology showed a
possible benefit to coffee consumption in patients with hepatitis C,
First I will show the treatment of the study as shown in the popular
press, then the actual journal article.
Could Stall Liver Disease Progression
By Kristina Fiore, Staff Writer, MedPage Today
Published: October 21, 2009
Reviewed by Robert Jasmer, MD; Associate Clinical Profe........ Read more »
Freedman, N., Everhart, J., Lindsay, K., Ghany, M., Curto, T., Shiffman, M., Lee, W., Lok, A., Di Bisceglie, A., Bonkovsky, H.... (2009) Coffee intake is associated with lower rates of liver disease progression in chronic hepatitis C. Hepatology, 50(5), 1360-1369. DOI: 10.1002/hep.23162
"I feel your pain"Empathy for another person's pain is a hot topic of study in the glamorous field of social cognitive neuroscience. The capacity for empathy supposedly involves mirror neurons, those media darlings of The Young, [The Not-So-Young], and The Neuro:A mirror neuron is a neuron that fires both when an animal acts and when the animal observes the same action performed by another. Thus, the neuron "mirrors" the behavior of the other, as though the observer were itself acting.These magi........ Read more »
Recently Wolinska and Spaak (2009) provide a survey of Daphnia infections by genotype across a number of lakes in Italy and Switzerland. They present their results as empirical evidence of Red Queen dynamics in which coevolution with virulent parasites generates continued evolution. Although Van Valen (1973) originally presented a macroevolutionary argument where by reciprocal selection of hosts and their parasites generates conditions for continuous change, Bell (1982) narrowed the focus as a........ Read more »
Wolinska, J., & Spaak, P. (2009) The cost of being common: evidence from natural Daphnia populations. Evolution, 63(7), 1893-1901. DOI: 10.1111/j.1558-5646.2009.00663.x
An article entitled University Public-Access Mandates are Good for Science by David Shulenburger was published in PLoS Biology this week. It is a great read, and a topic I feel passionate about. As the article states:
“Not many taxpayers know what university faculty are doing. In fact, not many university administrators or even other faculty know [...]... Read more »
David Shulenburger. (2009) University Public-Access Mandates Are Good for Science. PLoS Biology, 7(11). info:/
–Patterson KD, & Pyle GF (1991). The geography and mortality of the 1918 influenza pandemic. Bulletin of the history of medicine, 65 (1), 4-21 PMID: 2021692
(Click on the image for a larger version)
... Read more »
Patterson KD, & Pyle GF. (1991) The geography and mortality of the 1918 influenza pandemic. Bulletin of the history of medicine, 65(1), 4-21. PMID: 2021692
Herman Schatzl, who recently received an endowed chair at the University of Wyoming, and colleagues published an article in The Journal of Biological Chemistry early this year on the effects of prion proteins on the expression of cholesterol-associated genes. The experiment was an in vitro study using cultured neurons that were infected with the 22L prion strain. They examined gene expression of genes involved in the cholesterol pathway in neurons and supportive cells. The authors........ Read more »
Bach C, Gilch S, Rost R, Greenwood AD, Horsch M, Hajj GN, Brodesser S, Facius A, Schädler S, Sandhoff K.... (2009) Prion-induced activation of cholesterogenic gene expression by Srebp2 in neuronal cells. The Journal of biological chemistry, 284(45), 31260-9. PMID: 19748890
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