... Read more »
Nelson, K., Gray, E., & Evans, J. (2010) Finding solutions for bird restoration and livestock management: Comparing grazing exclusion levels. Ecological Applications, 2147483647. DOI: 10.1890/10-0032
One of the unwanted complications of gaining a lot of weight and then losing it, is the sometimes grotesque amounts of unwanted skin that patients are left with. This excess skin can be both aethetically distressing but also cause functional and dermatological problems.
With the advent of bariatric surgery, a parallel discipline of plastic surgery specialising [...]... Read more »
Agha-Mohammadi S, & Hurwitz DJ. (2010) Enhanced Recovery After Body-Contouring Surgery: Reducing Surgical Complication Rates by Optimizing Nutrition. Aesthetic plastic surgery. PMID: 20464396
Mutations are as you know a double-edged sword. On the one hand mutations are the stuff of evolution; neutral changes on the molecular or phenotypic level are the result of from mutations, as are changes which enhance fitness and so are driven to fixation by positive selection. On the other hand mutations also tend to [...]... Read more »
Tomkins, J., Penrose, M., Greeff, J., & LeBas, N. (2010) Additive Genetic Breeding Values Correlate with the Load of Partially Deleterious Mutations. Science, 328(5980), 892-894. DOI: 10.1126/science.1188013
This weekend, newspaper headlines announced that “Cancer Scientists hail ‘huge’ leap towards jab that targets tumours” and “’Holy Grail’ cancer vaccine that blasts tumours in weeks hailed as huge leap in fighting disease”. Not only are these headlines overhyped and misleading, but the stories themselves are slightly confusing, combining the launch of a clinical trial [...]... Read more »
Joshi, P., Jackson, H., Beristain, A., Di Grappa, M., Mote, P., Clarke, C., Stingl, J., Waterhouse, P., & Khokha, R. (2010) Progesterone induces adult mammary stem cell expansion. Nature. DOI: 10.1038/nature09091
The incorporation of current scientific research and understanding into on the ground conservation projects not only increases the effectiveness of those conservation efforts, it also builds support for their implementation. A new case study serves as an example of the benefits that come from outreach work that includes creative methods for communicating science to diverse audiences...... Read more »
Grorud-Colvert, K., Lester, S., Airame, S., Neeley, E., & Gaines, S. (2010) Marine Reserves Special Feature: Communicating marine reserve science to diverse audiences. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.0914292107
In November of 1793 a British naval expedition commanded by Captain George Vancouver arrived at the small Spanish settlement of Santa Barbara on the coast of California. Vancouver’s primary mission was to explore and map the poorly understood northwest coast of North America, building on the more preliminary information provided earlier by Captain James Cook. [...]... Read more »
Heizer, R. (1938) An Inquiry into the Status of the Santa Barbara Spear-Thrower. American Antiquity, 4(2), 137. DOI: 10.2307/275985
Read, C. (1892) An Account of a Collection of Ethnographical Specimens Formed During Vancouver's Voyage in the Pacific Ocean, 1790-1795. The Journal of the Anthropological Institute of Great Britain and Ireland, 99. DOI: 10.2307/2842277
Also posted over at Paramedicine 101 and at Research Blogging. Go check out the rest of the excellent material at both sites.This is an older study that puts the prehospital pain management problem into a bit of perspective. While prehospital pain management has improved a lot in some places, other places may still be handling pain as described in this study. This is only ten years old. Attitudes are not changed so easily. The authors looked at what is probably the least controversial type of pa........ Read more »
White, L., Cooper, J., Chambers, R., & Gradisek, R. (2000) P REHOSPITAL U SE OF A NALGESIA FOR S USPECTED E XTREMITY F RACTURES. Prehospital Emergency Care, 4(3), 205-208. DOI: 10.1080/10903120090941209
Two papers out this week on the population dynamics and epidemiology of the chytrid pathogen of amphibians, Batrachochytrium dendrobatidis (Bd). This is work from the Vredenburg and Briggs labs that includes several decade-long studies of frog declines and the prevalence of Bd.
See Vance in action swabbing a frog
In the Briggs et al paper, they [...]... Read more »
Briggs, C., Knapp, R., & Vredenburg, V. (2010) Enzootic and epizootic dynamics of the chytrid fungal pathogen of amphibians. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.0912886107
Vredenburg, V., Knapp, R., Tunstall, T., & Briggs, C. (2010) Dynamics of an emerging disease drive large-scale amphibian population extinctions. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.0914111107
Reading a book for the second time can be an enlightening experience. At the same time, aspects of this experience can be confusing. During a second visit to a work previously read I suspect that to a degree everyone plays a game that involves trying to determine which parts of the story you remember well and which parts you completely forgot. But there are also parts that lie somewhere in the middle; it is these parts that boggle our minds by leaving us uncertain of whether or not the details a........ Read more »
O'Connor AR, & Moulin CJ. (2010) Recognition without identification, erroneous familiarity, and déjà vu. Current psychiatry reports, 12(3), 165-73. PMID: 20425276
A guide for emergency medicine registrars and residents on how to be an effective clinical teacher.... Read more »
Houghland JE, & Druck J. (2010) Effective clinical teaching by residents in emergency medicine. Annals of Emergency Medicine, 55(5), 434-9. PMID: 20031266
Ahead of a landmark study, newspapers all around the world have carried news reports warning of the terrible risk faced by mobile phone users.
The story behind the story is worth a few words. Firstly, the study seems to says opposite to what all these reports claim. Secondly, the study was under embargo until the [...]... Read more »
Elisabeth Cardis. (2010) Brain tumour risk in relation to mobile telephone use: results of the INTERPHONE international case–control study. International Journal of Epidemiology, 1-20. info:/10.1093/ije/dyq079
Here is a final installment in our coverage of the Middlekoop paper. First up, we had Neil O’Connell talking about elephants and then we had Peter O’Sullivan raising some provocative thoughts on the value of our current direction in trying to evaluate exercise as a treatment for back pain. Now, from that odd group of [...]... Read more »
 van Middelkoop M, Rubinstein SM, Verhagen AP, Ostelo RW, Koes BW, & van Tulder MW. (2010) Exercise therapy for chronic nonspecific low-back pain. Best practice , 24(2), 193-204. PMID: 20227641
One thing that strikes me as very different about the ACT approach is the very different way therapists are encouraged to respond to difficult emotions. Part of ACT is to encourage acceptance of, and ‘sitting with’ negative thoughts or emotions or sensations rather than attempting to change them or ignore them – and in my … Read more... Read more »
McCracken, L., & Vowles, K. (2008) A prospective analysis of acceptance of pain and values-based action in patients with chronic pain. Health Psychology, 27(2), 215-220. DOI: 10.1037/0278-6184.108.40.206
MCCRACKEN, L. (2007) A Contextual Analysis of Attention to Chronic Pain: What the Patient Does With Their Pain Might Be More Important Than Their Awareness or Vigilance Alone. The Journal of Pain, 8(3), 230-236. DOI: 10.1016/j.jpain.2006.08.004
Invasive vine could worsen ozone pollution in southeastern US
... Read more »
Hickman, J.E., Wu, S., Mickley, L.J., & M.T. Lerdau. (2010) Kudzu (Pueraria montana) invasion doubles emissions of nitric oxide and increases ozone pollution. Proceedings of the National Academy of Sciences. info:/10.1073/pnas.0912279107
Cyber-bullying is a growing problem, but it’s so new that there’s not much research about it. So Krystal D’Costa begins her work studying cyber-bullying by considering what goes into real-world bullying.
Each week, Kevin Zelnio, Razib Khan, and I choose one or more journal articles to discuss in podcast form. This week, while Kevin is on [...]... Read more »
Mayer, J., Salovey, P., & Caruso, D. (2004) TARGET ARTICLES: "Emotional Intelligence: Theory, Findings, and Implications". Psychological Inquiry, 15(3), 197-215. DOI: 10.1207/s15327965pli1503_02
Snyder, J., Brooker, M., Patrick, M., Snyder, A., Schrepferman, L., & Stoolmiller, M. (2003) Observed Peer Victimization During Early Elementary School: Continuity, Growth, and Relation to Risk for Child Antisocial and Depressive Behavior. Child Development, 74(6), 1881-1898. DOI: 10.1046/j.1467-8624.2003.00644.x
Child development produces marked changes in attention, impulsivity and activity levels. Preschool children present a significant challenge for the diagnosis of ADHD because of their typical activity and attention levels. It is possible that the diagnosis of ADHD in some young children might be incorrect due to delayed maturation.Swedish researchers looked at this issue in a study of children examined in grades one and two and then re-studied in eighth grade. A child who was hyperactive/inatte........ Read more »
Gustafsson P, Holmström E, Besjakov J, & Karlsson MK. (2010) ADHD symptoms and maturity - a follow up study in school children. Acta paediatrica (Oslo, Norway : 1992). PMID: 20456272
Although the hydra may only be known as a Greek myth, head regrowth is actually not as fantastical as it may seem.
According Greek mythology, the hydra was a nine-headed serpent slain by Hercules. What made the feat challenging was that every time Hercules cut off one of the serpent’s heads, two new heads replaced [...]... Read more »
Petersen, C., & Reddien, P. (2008) Smed- catenin-1 Is Required for Anteroposterior Blastema Polarity in Planarian Regeneration. Science, 319(5861), 327-330. DOI: 10.1126/science.1149943
Felix DA, & Aboobaker AA. (2010) The TALE class homeobox gene Smed-prep defines the anterior compartment for head regeneration. PLoS genetics, 6(4). PMID: 20422023
I had no idea my sleep-wake cycle was pathological until I saw a presentation a few years ago by the geneticist Thomas Bourgeron. One of his interests is clock genes in autism. In fact only by speaking with him did it dawn on me that I lack a circadian rhythm.As it turns out, autistics are considered to have circadian clocks "gone bad." Two reviews (Bourgeron, 2007; Glickman, 2010) cover the evidence with respect to autism and circadian rhythms, most of it in the direction of comprehensive atypi........ Read more »
Bourgeron, T. (2007) The Possible Interplay of Synaptic and Clock Genes in Autism Spectrum Disorders. Cold Spring Harbor Symposia on Quantitative Biology, 72(1), 645-654. DOI: 10.1101/sqb.2007.72.020
Glickman, G. (2010) Circadian rhythms and sleep in children with autism. Neuroscience , 34(5), 755-768. DOI: 10.1016/j.neubiorev.2009.11.017
Migraines are severe, often debilitating, headaches that may be accompanied by visual symptoms, as well as nausea and vomiting. Migraines may last up to 24 hours. The exact cause of migraine is unknown, and most treatment focuses on acute pain relief once the migraine begins. For many migraine sufferers, acute pain relief is often ineffective [...]... Read more »
Goldstein J, Silberstein SD, Saper JR, Ryan RE Jr, & Lipton RB. (2006) Acetaminophen, aspirin, and caffeine in combination versus ibuprofen for acute migraine: results from a multicenter, double-blind, randomized, parallel-group, single-dose, placebo-controlled study. Headache, 46(3), 444-53. PMID: 16618262
Kirthi V, Derry S, Moore RA, & McQuay HJ. (2010) Aspirin with or without an antiemetic for acute migraine headaches in adults. Cochrane database of systematic reviews (Online). PMID: 20393963
Lampl C, Voelker M, & Diener HC. (2007) Efficacy and safety of 1,000 mg effervescent aspirin: individual patient data meta-analysis of three trials in migraine headache and migraine accompanying symptoms. Journal of neurology, 254(6), 705-12. PMID: 17406776
Paemeleire K, & Bartsch T. (2010) Occipital nerve stimulation for headache disorders. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 7(2), 213-9. PMID: 20430321
Steiner TJ, & Voelker M. (2009) Gastrointestinal tolerability of aspirin and the choice of over-the-counter analgesia for short-lasting acute pain. Journal of clinical pharmacy and therapeutics, 34(2), 177-86. PMID: 19250138
A recent paper by Kien Trinh et al. in the Journal of Neuroscience suggests that coffee and tobacco have a protective effect in two fruit fly models of Parkinson's disease. Surprisingly, these effects do not depend on the obvious "active ingredients" of these substances (i.e., caffeine and nicotine), but occur through some alternative mechanism.The connection between coffee consumption and lower risk of Parkinson's disease has been known for a while. When I was applying for research assistant po........ Read more »
Trinh, K., Andrews, L., Krause, J., Hanak, T., Lee, D., Gelb, M., & Pallanck, L. (2010) Decaffeinated Coffee and Nicotine-Free Tobacco Provide Neuroprotection in Drosophila Models of Parkinson's Disease through an NRF2-Dependent Mechanism. Journal of Neuroscience, 30(16), 5525-5532. DOI: 10.1523/JNEUROSCI.4777-09.2010
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