Post List

  • November 16, 2009
  • 08:00 AM

Water vapor and global warming

by David Bradley in SciScoop Science Forum

With Copenhagen on the horizon, is it time to check over the physics and chemistry behind the climate change debate? SciScoop has spoken to several scientists recently who would say so, some of whom consider the climate change debate nothing more than a hell-on-earth scenario to give governments a taxation stick with which to beat [...]... Read more »

  • November 16, 2009
  • 08:00 AM

How to act when you might be eaten

by Zen Faulkes in NeuroDojo

If you don’t have to worry about reproduction, life gets a little simpler. You have to worry about eating. You have to worry about being eaten. And with that, you’re pretty close to done.

Aspidoscelis uniparens is a parthenogenetic whiptail lizard (formerly Cnemidophorus uniparens), and Eifler and colleagues tested how they allocated their time under threat. To do they, they made six large enclosures (225 square meters) and put in six of these small lizards in. In half of these, the........ Read more »

  • November 16, 2009
  • 07:57 AM

Does the clinical benefit of a drug justify it's cost?

by Sally Church in Pharma Strategy Blog

The Obama administration provided $1.1 billion for health care comparative effectiveness research in the American Recovery and Reinvestment Act (ARRA). Following this, the Institute of Medicine (IOM) delivered a report in June with comparative effectiveness research priorities (downloadable file). However,...... Read more »

  • November 16, 2009
  • 06:00 AM

Pandemic patterns: Is the influenza pandemic going away?

by iayork in Mystery Rays from Outer Space

The number of influenza cases this year seems to have peaked and started to drop in the last few weeks, according to both the CDC surveillance data and Google Flu Trends (which updates more in real-time).  Does that mean swine-origin influenza virus is gone for good? We don’t know, of course, but I was struck [...]... Read more »

Taubenberger JK, & Morens DM. (2006) 1918 Influenza: the mother of all pandemics. Emerging infectious diseases, 12(1), 15-22. PMID: 16494711  

D. A. Henderson, Brooke Courtney, Thomas V. Inglesby, Eric Toner, & Jennifer B. Nuzzo. (2009) Public Health and Medical Responses to the 1957-58 Influenza Pandemic. Biosecurity and Bioterrorism, 7(3), 1-9. info:/

  • November 16, 2009
  • 06:00 AM

ACL Reconstruction Rehabilitation – The Long Term Effects of 2 Postoperative Rehabilitation Programs

by Mike Reinold in

A new study examining the outcomes of two different rehabilitation programs following anterior cruciate ligament (ACL) reconstruction was recently published in AJSM.  The authors, from Oslo University in Norway, compared the outcomes from two groups of 74 patients (mean age 28 years old) after 6 months of rehabilitation. Group one performed a neuromuscular exercise program consisting of what the authors defined as balance exercises, dynamic joint stability exercises, plyometric exercise........ Read more »

  • November 16, 2009
  • 05:24 AM

Testosterone-status mismatch in a group is linked with reduced collective confidence

by Christian Jarrett in BPS Research Digest

Men and women with more testosterone like to be in charge. Indeed, they can find it stressful and uncomfortable when denied the status that they crave. Similarly, people low in testosterone find it uncomfortable to be placed in positions of authority. An intriguing new study has built on these earlier findings, showing a mismatch between testosterone-level and status can have an effect on group functioning. Groups made up of people whose status in the group doesn't match their testosterone level........ Read more »

  • November 16, 2009
  • 02:35 AM

The Neuroscience of Music Enjoyment and Depression

by Dr Shock in Dr Shock MD PhD

When feeling down good music can cheer you up. But when depressed, I mean clinically depressed, can you enjoy music? How is music enjoyment processed by the brain and how is this influenced by depression?
All participants of this study enjoyed their favorite music more than the neutral music and depressed patients didn’t differ from the [...]

Related posts:The Neurobiology of Empathy through Pain Research There are patients with congenital insensitivity to pain (CIP) this...Neuroscienc........ Read more »

Osuch, E., Bluhm, R., Williamson, P., Théberge, J., Densmore, M., & Neufeld, R. (2009) Brain activation to favorite music in healthy controls and depressed patients. NeuroReport, 20(13), 1204-1208. DOI: 10.1097/WNR.0b013e32832f4da3  

  • November 16, 2009
  • 02:35 AM

Theories of emotion, self-regulation and pain

by Bronwyn Thompson in Healthskills: Skills for Healthy Living

Can chronic pain be a force that shapes how we go about responding to challenges within our environments?
Does chronic pain influence how we feel emotionally about daily activities that contribute to overall goals, and perhaps negatively bias the way we think about the process of setting and achieving goals?
I’ve already concluded that having [...]... Read more »

Hamilton, N., Karoly, P., & Kitzman, H. (2004) Self-Regulation and Chronic Pain:The Role of Emotion. Cognitive Therapy and Research, 28(5), 559-576. DOI: 10.1023/B:COTR.0000045565.88145.76  

  • November 16, 2009
  • 12:23 AM

Targeted Sequencing Bags a Rare Disease

by Keith Robison in Omics! Omics!

Nature Genetics on Friday released the paper from Jay Shendure, Debra Nickerson and colleagues which used targeted sequencing to identify the damaged gene in a rare Mendelian disorder, Miller syndrome. The work had been presented at least in part at recent meetings, but now all of us can digest it in entirety.The impressive economy of this paper is that they targeted (using Agilent chips) less than 30Mb of the human genome, which is less than 1%. They also worked with very few samples; only ab........ Read more »

Sarah B. Ng, Kati J. Buckingham, Choli Lee, Abigail W. Bigham, Holly K. Tabor, Karin M. Dent, Chad D. Huff, Paul T. Shannon, Ethylin Wang Jabs, Deborah A. Nickerson.... (2009) Exome sequencing identifies the cause of a mendelian disorder. Nature genetics. info:/doi:10.1038/ng.499

  • November 15, 2009
  • 10:38 PM

Resilience to climate change: a Mexico example

by Paul Spraycar in Beyond Climate Change

Climate modeling is hard. The Earth’s climate system is complex, with infinite interactions and feedbacks that interact across scales. There is often uncertainty, and a result the models are inherently imprecise.Nonetheless, they’re a powerful tool, and they get better every day. Scaling down these models is critical to providing a better prediction of future climate and rainfall patterns. And a recent study in Environment, Development and Sustainability does exactly this to show wha........ Read more »

  • November 15, 2009
  • 06:01 PM

Supply, Demand, and…”Miscellanous” Risk?

by Jan Husdal in

The other day I was proofreading the paper of a colleague when this paper in the reference list caught my attention. Not familiar with retail supply chains, here was a chance to learn something new…so I thought, and so I did. However, I’m not sure I follow the authors in their risk categorization: supply, demand and “miscellanous” risk? What is this “miscellanous” risk?
... Read more »

  • November 15, 2009
  • 01:22 PM

Can wildlife farming save rare animals from being hunted to extinction?

by Rob Goldstein in Conservation Maven

Wildlife farming in Southeast Asia has emerged as a potential conservation tool for rare and threatened species that are regularly poached in the wild primarily for upscale consumers in urban markets. But a new study finds that it has unintended negative more... Read more »

  • November 15, 2009
  • 10:10 AM

Recharge Your Batteries

by calvinus in Post Tenebras Lux

New materials to make batteries with might actually rival petrol for energy storage capacity.... Read more »

Licht, S., Wu, H., Yu, X., & Wang, Y. (2008) Renewable highest capacity VB2/air energy storage. Chemical Communications, 3257. DOI: 10.1039/b807929c  

  • November 15, 2009
  • 06:13 AM

Trends in bacterial signalling pathways

by Lab Rat in Lab Rat

Bacterial (and archaeal) signalling systems are remarkably similar to eukaryotic ones. As well as the typical and well described two-component signalling systems (a histadine-kinase sensor which senses a signal and passes this on to a response-regulator) bacteria also contain multi-component systems, for both inter- and intra-cellular signalling.All cells constantly monitor their external and internal environment in order to effectively exploit their surroundings. Bacteria are no different, and ........ Read more »

  • November 15, 2009
  • 02:40 AM

Good News for Coffee Drinkers

by j7uy5 in The Corpus Callosum

Actually, this is only good news
for coffee drinkers who also have
late-stage hepatitis C.  A recent study in Hepatology showed a
possible benefit to coffee consumption in patients with hepatitis C,

First I will show the treatment of the study as shown in the popular
press, then the actual journal article.

Could Stall Liver Disease Progression
By Kristina Fiore, Staff Writer, MedPage Today
Published: October 21, 2009

Reviewed by Robert Jasmer, MD; Associate Clinical Profe........ Read more »

Freedman, N., Everhart, J., Lindsay, K., Ghany, M., Curto, T., Shiffman, M., Lee, W., Lok, A., Di Bisceglie, A., Bonkovsky, H.... (2009) Coffee intake is associated with lower rates of liver disease progression in chronic hepatitis C. Hepatology, 50(5), 1360-1369. DOI: 10.1002/hep.23162  

  • November 15, 2009
  • 12:19 AM

I Feel Your Pain, I REALLY Do: Synaesthesia for Another's Pain

by The Neurocritic in The Neurocritic

"I feel your pain"Empathy for another person's pain is a hot topic of study in the glamorous field of social cognitive neuroscience. The capacity for empathy supposedly involves mirror neurons, those media darlings of The Young, [The Not-So-Young], and The Neuro:A mirror neuron is a neuron that fires both when an animal acts and when the animal observes the same action performed by another. Thus, the neuron "mirrors" the behavior of the other, as though the observer were itself acting.These magi........ Read more »

Fitzgibbon, B., Giummarra, M., Georgiou-Karistianis, N., Enticott, P., & Bradshaw, J. (2009) Shared pain: From empathy to synaesthesia. Neuroscience . DOI: 10.1016/j.neubiorev.2009.10.007  

  • November 14, 2009
  • 05:11 PM

Is the Red Queen showing her face? Evidence of negative frequency dependent selection by parasites

by Devin Drown in Coevolvers

Recently Wolinska and Spaak (2009) provide a survey of Daphnia infections by genotype across a number of lakes in Italy and Switzerland. They present their results as empirical evidence of Red Queen dynamics in which coevolution with virulent parasites generates continued evolution. Although Van Valen (1973) originally presented a macroevolutionary argument where by reciprocal selection of hosts and their parasites generates conditions for continuous change, Bell (1982) narrowed the focus as a........ Read more »

  • November 14, 2009
  • 03:40 PM

Open Science Sunday – 15.11.09

by kubke in Building Blogs of Science

An article entitled University Public-Access Mandates are Good for Science by David Shulenburger was published in PLoS Biology this week. It is a great read, and a topic I feel passionate about. As the article states:
“Not many taxpayers know what university faculty are doing. In fact, not many university administrators or even other faculty know [...]... Read more »

David Shulenburger. (2009) University Public-Access Mandates Are Good for Science. PLoS Biology, 7(11). info:/

  • November 14, 2009
  • 01:26 PM

On the spread of the 1918 influenza

by iayork in Mystery Rays from Outer Space

–Patterson KD, & Pyle GF (1991). The geography and mortality of the 1918 influenza pandemic. Bulletin of the history of medicine, 65 (1), 4-21 PMID: 2021692
(Click on the image for a larger version)
... Read more »

Patterson KD, & Pyle GF. (1991) The geography and mortality of the 1918 influenza pandemic. Bulletin of the history of medicine, 65(1), 4-21. PMID: 2021692  

  • November 14, 2009
  • 12:25 PM

Prions activate neuronal cholesterogenic gene expression

by Brian Appleby in CJD Blogger

Herman Schatzl, who recently received an endowed chair at the University of Wyoming, and colleagues published an article in The Journal of Biological Chemistry early this year on the effects of prion proteins on the expression of cholesterol-associated genes.  The experiment was an in vitro study using cultured neurons that were infected with the 22L prion strain.  They examined gene expression of genes involved in the cholesterol pathway in neurons and supportive cells. The authors........ Read more »

Bach C, Gilch S, Rost R, Greenwood AD, Horsch M, Hajj GN, Brodesser S, Facius A, Schädler S, Sandhoff K.... (2009) Prion-induced activation of cholesterogenic gene expression by Srebp2 in neuronal cells. The Journal of biological chemistry, 284(45), 31260-9. PMID: 19748890  

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