This animal could kill seven people.
No wonder it looks a little smug.
That newt “Sure, you might try and eat me, but when your brain stops, I’ll have the last laugh, sucker.”
And that newt wouldn’t be kidding.
Some rough skinned newts (Taricha granulosa) have something in common with poison dart frogs, blue-ringed octopus, and pufferfish. They all contain within them a poison called tetrodotoxin.
Tetrodotoxin is a neurotoxin that stops neurons from initiating action potentials. I........ Read more »
Lee C, Jones D, Ahern C, Sarhan M, & Ruben P. (2010) Biophysical costs associated with tetrodotoxin resistance in the sodium channel pore of the garter snake, Thamnophis sirtalis. Journal of Comparative Physiology A. DOI: 10.1007/s00359-010-0582-9
The publisher Henry Holt and Company was kind enough to send me a review copy of Guy Deutscher's new book Through the Language Glass: Why the World Looks Different in Other Languages which bills itself as "demonstrating that language does in fact reflect culture in ways that are anything but trivial" but which also goes beyond that and purports to demonstrate that language affects thought, if only via habits of mind.This is part one of a two part review. I expect to post Part 2 next Monday, Sept........ Read more »
Guy Deutscher. (2010) Through the Language Glass: Why the World Looks Different in Other Languages. Metropolitan Books. info:/
How do cells do mechanical work to move, and divide? The filaments that make up the cytoskeleton, which provide the structure required for large-scale movement, are some of the most extraordinary assemblies in biology. These filaments are dynamic (they form where they are needed, then dissolve again), and they’re amazingly long and thin: tens of [...]... Read more »
Lee K, Gallop JL, Rambani K, & Kirschner MW. (2010) Self-assembly of filopodia-like structures on supported lipid bilayers. Science (New York, N.Y.), 329(5997), 1341-5. PMID: 20829485
"The problem with being on call every other night is that you miss half the cases!"Excessive resident fatigue was just par for training in the old days of Medicine before duty hours came into effect, thanks to the ACGME. In 2008, the Institute of Medicine (IOM) provided more restrictive duty-hour recommendations. Key leaders in Emergency Medicine convened to develop a consensus response to these IOM recommendations. The following is a summary of the response, published in Journal of Emergency Me........ Read more »
Wagner MJ, Wolf S, Promes S, McGee D, Hobgood C, Doty C, McErlean MA, Janssen A, Smith-Coggins R, Ling L.... (2010) Duty hours in emergency medicine: balancing patient safety, resident wellness, and the resident training experience: a consensus response to the 2008 institute of medicine resident duty hours recommendations. The Journal of emergency medicine, 39(3), 348-55. PMID: 20634017
by Peter Janiszewski, Ph.D. in Obesity Panacea
Welcome to our 5-part series delving into the fascinating and seemingly paradoxical research on people who despite being obese, remain metabolically-healthy. Today, we’ll start with an introduction.
To date, countless epidemiological studies have shown that as you move from a normal weight (BMI = 18.5-24.9 kg/m2) towards overweight (BMI = 25-29.9kg/m2) and obesity (BMI ≥ 30 kg/m2) the risk of many diseases increases exponentially.
Does this imply that every individual carrying excess ........ Read more »
Albrink, M., & Meigs, J. (1965) THE RELATIONSHIP BETWEEN SERUM TRIGLYCERIDES AND SKINFOLD THICKNESS IN OBESE SUBJECTS. Annals of the New York Academy of Sciences, 131(1 Adipose Tissu), 673-683. DOI: 10.1111/j.1749-6632.1965.tb34830.x
Sims, E. (2001) Are there persons who are obese, but metabolically healthy?. Metabolism, 50(12), 1499-1504. DOI: 10.1053/meta.2001.27213
Karelis, A. (2004) Metabolic and Body Composition Factors in Subgroups of Obesity: What Do We Know?. Journal of Clinical Endocrinology , 89(6), 2569-2575. DOI: 10.1210/jc.2004-0165
The recent financial crisis is partly due to leaders abusing their power for self-interest. CEO’s and other leaders are responsible for the promotion and welfare of their clients and workers. Instead of wielding their power for the greater good, leaders might be tempted to use their power in self-serving ways. What makes leaders use their [...]
Related posts:On Leading a Research Group
How great leaders inspire action
Conflicts of Interest in Medical Journal Publishing
... Read more »
Maner, J., & Mead, N. (2010) The essential tension between leadership and power: When leaders sacrifice group goals for the sake of self-interest. Journal of Personality and Social Psychology, 99(3), 482-497. DOI: 10.1037/a0018559
Upcoming Mars rover mission, yet to be greenlit, but has an interesting strategy..... Read more »
Lisa Pratt, David Beaty, Abigail Allwood. (2010) The Mars Astrobiology Explorer-Cacher (MAX-C): A Potential Rover Mission for 2018. Astrobiology, 10(2), 127-163. DOI: 10.1089/ast.2010.0462
What is it good for? Well, the development of some interesting mathematics, if nothing else. And raised eyebrows. And scheming/strategising.
Last Monday morning (yes yes, I know – been busy, ‘k?!) I successfully managed to hie myself off to Dr Sean Gourley’s speech about, you guessed it, the mathematics of war.
Or, to be particular, the [...]
[Click on the hyperlinked headline for more of the goodness]... Read more »
[Wherein our Hero muses why money buys happiness so easily, and why it might also buy power, independence and sense of perspective.] So I’ve just come back from The Philippines. It was relatively rushed holiday, given that we were invited over rather than having planned to go for a fair period. As such we had [...]... Read more »
Dubois, D., Rucker, D., & Galinsky, A. (2010) The Accentuation Bias: Money Literally Looms Larger (and Sometimes Smaller) to the Powerless. Social Psychological and Personality Science, 1(3), 199-205. DOI: 10.1177/1948550610365170
Zhou X, Vohs KD, & Baumeister RF. (2009) The symbolic power of money: reminders of money alter social distress and physical pain. Psychological science : a journal of the American Psychological Society / APS, 20(6), 700-6. PMID: 19422625
A professor once told me that if you removed everything from earth and just left the nematodes you would still recognize the outlines of everything. I have absolutely no idea if this is even remotely true. I do know that, hyperbole aside, nematodes represent one of the most abundant forms of life on earth. The phyla . . . → Read More: How Many Deep-Sea Nematodes Are There & Why We Many Never Know... Read more »
Miljutin, D., Gad, G., Miljutina, M., Mokievsky, V., Fonseca-Genevois, V., & Esteves, A. (2010) The state of knowledge on deep-sea nematode taxonomy: how many valid species are known down there?. Marine Biodiversity, 40(3), 143-159. DOI: 10.1007/s12526-010-0041-4
Lambshead, P., & Boucher, G. (2003) Marine nematode deep-sea biodiversity - hyperdiverse or hype?. Journal of Biogeography, 30(4), 475-485. DOI: 10.1046/j.1365-2699.2003.00843.x
Everybody likes cuttlefish, it seems. They’re neat-looking, sociable, and display lots of entertaining behavior. I think it’s about time, then, to start talking about what cuttlefish do best: change color! I’ll start at what is, as far as I can tell, the beginning. In 1988, Roger Hanlon and John Messenger published a paper called “Adaptive [...]... Read more »
Hanlon, R., & Messenger, J. (1988) Adaptive Coloration in Young Cuttlefish (Sepia Officinalis L.): The Morphology and Development of Body Patterns and Their Relation to Behaviour. Philosophical Transactions of the Royal Society B: Biological Sciences, 320(1200), 437-487. DOI: 10.1098/rstb.1988.0087
Nir Goldman (Lawrence Livermore National Laboratory, United States) and coworkers' computer simulations suggest that the high temperatures and pressures of cometary impacts are sometimes within a range compatible with comets as a catalyst for amino acid synthesis in pre-life Earth. This news feature was written on September 12, 2010.... Read more »
Goldman, N., Reed, E. J., Fried, L. E., William Kuo, I.-F., & Maiti, A. (2010) Synthesis of glycine-containing complexes in impacts of comets on early Earth. Nature Chemistry. DOI: 10.1038/nchem.827
The extended mind/cognition hypothesis is that objects in our environments can literally become part of our cognition. This has numerous implications for how we should be doing psychology and neuroscience, but the argument is currently most robust in the philosophy of mind literature. Two staunch critics are Adams & Aizawa, who claim the hypothesis is grounded in a fallacy.... Read more »
In the following I summarize the major points of the article "Responsive supply chain: A competitive strategy in a networked economy" by Gunasekaran, Lai and Cheng (2008).
Responsive Supply Chain (RSC)
The authors define a RSC to contain both aspects of Agile Manufacturing and Supply Chain Management. They argue, that both complement each other in the objective to improve organizational competitiveness.
The concept of SCM, Agile manufacturing and RSC can be compared as follows:
Comparison........ Read more »
Gunasekaran, A., Lai, K., & Cheng, T. C. E. (2008) Responsive supply chain: A competitive strategy in a networked economy☆. Omega, 36(4), 549-564. DOI: 10.1016/j.omega.2006.12.002
Although ovarian clear cell carcinoma does not respondwell to conventional platinum–taxane chemotherapyfor ovarian carcinoma, this remainsthe adjuvant treatment of choice, because effectivealternatives have not been identified.This sentence is a depressing reminder of the status of medical treatment of far too many tumor types. Present in roughly 12% of U.S. ovarian cancer cases, ovarian clear cell carcinoma (OCCC) is a dreadful diagnosis.Two papers this week made a significant step forward i........ Read more »
Kimberly C. Wiegand, Sohrab P. Shah, Osama M. Al-Agha, Yongjun Zhao, Kane Tse, Thomas Zeng, Janine Senz, Melissa K. McConechy, Michael S. Anglesio, Steve E. Kalloger, Winnie Yang, Alireza Heravi-Moussavi, Ryan Giuliany,Christine Chow, John Fee, Abdalnas. (2010) ARID1A Mutations in Endometriosis-Associated Ovarian Carcinomas. New England Journal of Medicine. info:/10.1056/NEJMoa1008433
Jones S, Wang TL, Shih IM, Mao TL, Nakayama K, Roden R, Glas R, Slamon D, Diaz LA Jr, Vogelstein B.... (2010) Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma. Science (New York, N.Y.). PMID: 20826764
by Kimie Takahashi 高橋君江 in Language on the Move
The latest issue of Cross-Cultural Studies (published by the Center for Cross Cultural Studies, Hyung Hee University, Korea) includes an article about the dark side of TESOL authored by Ingrid Piller, Kimie Takahashi, and Yukinori Watanabe. Based on case studies from … Continue reading →... Read more »
Ingrid Piller, Kimie Takahashi, & Yukinori Watanabe. (2010) The Dark Side of TESOL: The Hidden Costs of the Consumption of English. Cross-Cultural Studies, 183-201. info:/
David Goldstein (Duke University, United States) and coworkers report steps towards unraveling the extent of human genetic variation, useful for directing medical effort towards genes critical to life. This news feature was written on September 12, 2010.... Read more »
Pelak, K., Shianna, K. V., Ge, D., Maia, J. M., Zhu, M., Smith, J. P., Cirulli, E. T., Fellay, J., Dickson, S. P., Gumbs, C. E.... (2010) The Characterization of Twenty Sequenced Human Genomes. PLoS Genetics, 6(9). DOI: 10.1371/journal.pgen.1001111
Original image here. Sea slugs are far more interesting than their name might imply. Aside from being beautiful, they have some unusual ways of making a living. In the case of a few unrelated species, they steal for a living. A handful of sea slugs have found away to make the most of the algae [...]... Read more »
Rumpho ME, Worful JM, Lee J, Kannan K, Tyler MS, Bhattacharya D, Moustafa A, & Manhart JR. (2008) Horizontal gene transfer of the algal nuclear gene psbO to the photosynthetic sea slug Elysia chlorotica. Proceedings of the National Academy of Sciences of the United States of America, 105(46), 17867-71. PMID: 19004808
Wagele, H., Deusch, O., Handeler, K., Martin, R., Schmitt, V., Christa, G., Pinzger, B., Gould, S., Dagan, T., Klussmann-Kolb, A.... (2010) Transcriptomic evidence that longevity of acquired plastids in the photosynthetic slugs Elysia timida and Plakobrachus ocellatus does not entail lateral transfer of algal nuclear genes. Molecular Biology and Evolution. DOI: 10.1093/molbev/msq239
The SGM autumn conference is now over - thanks to everyone who tweeted it so people like me could catch up on events without actually going. I've just got two more topics of my own little personal blog-conference to go, and this one is going to be on bacterial vesicles rather than secondary metabolism because it suddenly struck me that I don't actually know much about outer membrane vesicles, and this might be a good opportunity to explore them.So this is the penultimate post in my SGM topic ser........ Read more »
Kuehn MJ, & Kesty NC. (2005) Bacterial outer membrane vesicles and the host-pathogen interaction. Genes , 19(22), 2645-55. PMID: 16291643
How mature are you? Have you ever wanted to find out, with a 5 minute brain scan? Of course you have. And now you can, thanks to a new Science paper, Prediction of Individual Brain Maturity Using fMRI.This is another clever application of the support vector machine (SVM) method, which I've written about previously, most recently regarding "the brain scan to diagnose autism". An SVM is a machine learning algorithm: give it a bunch of data, and it'll find patterns in it.In this case, the input dat........ Read more »
Dosenbach NU, Nardos B, Cohen AL, Fair DA, Power JD, Church JA, Nelson SM, Wig GS, Vogel AC, Lessov-Schlaggar CN.... (2010) Prediction of individual brain maturity using fMRI. Science (New York, N.Y.), 329(5997), 1358-61. PMID: 20829489
Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.
If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.
Research Blogging is powered by SMG Technology.
To learn more, visit seedmediagroup.com.