Post List

  • September 13, 2010
  • 08:00 AM

Want to be immune to deadly poison? It’ll cost you

by Zen Faulkes in NeuroDojo

This animal could kill seven people.

No wonder it looks a little smug.

That newt “Sure, you might try and eat me, but when your brain stops, I’ll have the last laugh, sucker.”

And that newt wouldn’t be kidding.

Some rough skinned newts (Taricha granulosa) have something in common with poison dart frogs, blue-ringed octopus, and pufferfish. They all contain within them a poison called tetrodotoxin.

Tetrodotoxin is a neurotoxin that stops neurons from initiating action potentials. I........ Read more »

  • September 13, 2010
  • 07:33 AM

Through the Language Glass (Part 1)

by Chris in The Lousy Linguist

The publisher Henry Holt and Company was kind enough to send me a review copy of Guy Deutscher's new book Through the Language Glass: Why the World Looks Different in Other Languages which bills itself as "demonstrating that language does in fact reflect culture in ways that are anything but trivial" but which also goes beyond that and purports to demonstrate that language affects thought, if only via habits of mind.This is part one of a two part review. I expect to post Part 2 next Monday, Sept........ Read more »

Guy Deutscher. (2010) Through the Language Glass: Why the World Looks Different in Other Languages. Metropolitan Books. info:/

  • September 13, 2010
  • 07:06 AM

Dancing filopodia

by Becky in It Takes 30

How do cells do mechanical work to move, and divide? The filaments that make up the cytoskeleton, which provide the structure required for large-scale movement, are some of the most extraordinary assemblies in biology.  These filaments are dynamic (they form where they are needed, then dissolve again), and they’re amazingly long and thin: tens of [...]... Read more »

Lee K, Gallop JL, Rambani K, & Kirschner MW. (2010) Self-assembly of filopodia-like structures on supported lipid bilayers. Science (New York, N.Y.), 329(5997), 1341-5. PMID: 20829485  

  • September 13, 2010
  • 06:06 AM

Article review: EM consensus response to duty hour recommendations

by Michelle Lin in Academic Life In Emergency Medicine

"The problem with being on call every other night is that you miss half the cases!"Excessive resident fatigue was just par for training in the old days of Medicine before duty hours came into effect, thanks to the ACGME. In 2008, the Institute of Medicine (IOM) provided more restrictive duty-hour recommendations. Key leaders in Emergency Medicine convened to develop a consensus response to these IOM recommendations. The following is a summary of the response, published in Journal of Emergency Me........ Read more »

  • September 13, 2010
  • 06:00 AM

Metabolically-Healthy Obesity: An Oxymoron? (Series Pt 1/5)

by Peter Janiszewski, Ph.D. in Obesity Panacea

Welcome to our 5-part series delving into the fascinating and seemingly paradoxical research on people who despite being obese, remain metabolically-healthy. Today, we’ll start with an introduction.

To date, countless epidemiological studies have shown that as you move from a normal weight (BMI = 18.5-24.9 kg/m2) towards overweight (BMI = 25-29.9kg/m2) and obesity (BMI ≥ 30 kg/m2) the risk of many diseases increases exponentially.

Does this imply that every individual carrying excess ........ Read more »

  • September 13, 2010
  • 01:31 AM

When Leaders Sacrifice Group Goals for the Sake of Self-Interest

by Dr Shock in Dr Shock MD PhD

The recent financial crisis is partly due to leaders abusing their power for self-interest. CEO’s and other leaders are responsible for the promotion and welfare of their clients and workers. Instead of wielding their power for the greater good, leaders might be tempted to use their power in self-serving ways. What makes leaders use their [...]

Related posts:On Leading a Research Group
How great leaders inspire action
Conflicts of Interest in Medical Journal Publishing
... Read more »

  • September 13, 2010
  • 01:28 AM

MAX-C: What's the right way to do sample return?

by Casey Rentz in Natural Selections

Upcoming Mars rover mission, yet to be greenlit, but has an interesting strategy..... Read more »

  • September 12, 2010
  • 11:26 PM

The mathematics of war

by aimee in misc.ience

War!  Hngh!
What is it good for?  Well, the development of some interesting mathematics, if nothing else.  And raised eyebrows.  And scheming/strategising.
Last Monday morning (yes yes, I know – been busy, ‘k?!) I successfully managed to hie myself off to Dr Sean Gourley’s speech about, you guessed it, the mathematics of war.
Or, to be particular, the [...]

[Click on the hyperlinked headline for more of the goodness]... Read more »

Bohorquez, J., Gourley, S., Dixon, A., Spagat, M., & Johnson, N. (2009) Common ecology quantifies human insurgency. Nature, 462(7275), 911-914. DOI: 10.1038/nature08631  

  • September 12, 2010
  • 11:04 PM

…Loan me a dollar and we’ll both feel good

by Rift in Psycasm

[Wherein our Hero muses why money buys happiness so easily, and why it might also buy power, independence and sense of perspective.] So I’ve just come back from The Philippines. It was relatively rushed holiday, given that we were invited over rather than having planned to go for a fair period. As such we had [...]... Read more »

Dunn EW, Aknin LB, & Norton MI. (2008) Spending money on others promotes happiness. Science (New York, N.Y.), 319(5870), 1687-8. PMID: 18356530  

Vohs, K., Mead, N., & Goode, M. (2006) The Psychological Consequences of Money. Science, 314(5802), 1154-1156. DOI: 10.1126/science.1132491  

Zhou X, Vohs KD, & Baumeister RF. (2009) The symbolic power of money: reminders of money alter social distress and physical pain. Psychological science : a journal of the American Psychological Society / APS, 20(6), 700-6. PMID: 19422625  

  • September 12, 2010
  • 08:50 PM

How Many Deep-Sea Nematodes Are There & Why We Many Never Know

by Dr. M in Deep Sea News

A professor once told me that if you removed everything from earth and just left the nematodes you would still recognize the outlines of everything.  I have absolutely no idea if this is even remotely true.  I do know that, hyperbole aside, nematodes represent one of the most abundant forms of life on earth.  The phyla . . . → Read More: How Many Deep-Sea Nematodes Are There & Why We Many Never Know... Read more »

  • September 12, 2010
  • 08:15 PM

Cuttlefish Body Patterning

by Mike Mike in Cephalove

Everybody likes cuttlefish, it seems. They’re neat-looking, sociable, and display lots of entertaining behavior. I think it’s about time, then, to start talking about what cuttlefish do best: change color! I’ll start at what is, as far as I can tell, the beginning. In 1988, Roger Hanlon and John Messenger published a paper called “Adaptive [...]... Read more »

  • September 12, 2010
  • 08:10 PM

Did Comet Impacts Catalyze Amino Acid Production in Pre-Life Earth?

by Michael Long in Phased

Nir Goldman (Lawrence Livermore National Laboratory, United States) and coworkers' computer simulations suggest that the high temperatures and pressures of cometary impacts are sometimes within a range compatible with comets as a catalyst for amino acid synthesis in pre-life Earth. This news feature was written on September 12, 2010.... Read more »

  • September 12, 2010
  • 07:52 PM

Is Cognition Extended?

by Andrew Wilson in Notes from Two Scientific Psychologists

The extended mind/cognition hypothesis is that objects in our environments can literally become part of our cognition. This has numerous implications for how we should be doing psychology and neuroscience, but the argument is currently most robust in the philosophy of mind literature. Two staunch critics are Adams & Aizawa, who claim the hypothesis is grounded in a fallacy.... Read more »

Adams, F., Aizawa, K. (2001) The bounds of cognition. Philosophical Psychology, 14(1), 43-64. DOI: 10.1080/09515080120033571  

  • September 12, 2010
  • 07:25 PM

Foundation for a Responsive Supply Chain

by Daniel Dumke in SCRM Blog - Supply Chain Risk Management

In the following I summarize the major points of the article "Responsive supply chain: A competitive strategy in a networked economy" by Gunasekaran, Lai and Cheng (2008).

Responsive Supply Chain (RSC)
The authors define a RSC to contain both aspects of Agile Manufacturing and Supply Chain Management. They argue, that both complement each other in the objective to improve organizational competitiveness.

The concept of SCM, Agile manufacturing and RSC can be compared as follows:
Comparison........ Read more »

  • September 12, 2010
  • 05:58 PM

ARID1A A Fertile Ground for Mutations in Ovarian Clear Cell Carcinoma

by Keith Robison in Omics! Omics!

Although ovarian clear cell carcinoma does not respondwell to conventional platinum–taxane chemotherapyfor ovarian carcinoma, this remainsthe adjuvant treatment of choice, because effectivealternatives have not been identified.This sentence is a depressing reminder of the status of medical treatment of far too many tumor types. Present in roughly 12% of U.S. ovarian cancer cases, ovarian clear cell carcinoma (OCCC) is a dreadful diagnosis.Two papers this week made a significant step forward i........ Read more »

Kimberly C. Wiegand, Sohrab P. Shah, Osama M. Al-Agha, Yongjun Zhao, Kane Tse, Thomas Zeng, Janine Senz, Melissa K. McConechy, Michael S. Anglesio, Steve E. Kalloger, Winnie Yang, Alireza Heravi-Moussavi, Ryan Giuliany,Christine Chow, John Fee, Abdalnas. (2010) ARID1A Mutations in Endometriosis-Associated Ovarian Carcinomas. New England Journal of Medicine. info:/10.1056/NEJMoa1008433

Jones S, Wang TL, Shih IM, Mao TL, Nakayama K, Roden R, Glas R, Slamon D, Diaz LA Jr, Vogelstein B.... (2010) Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma. Science (New York, N.Y.). PMID: 20826764  

  • September 12, 2010
  • 05:30 PM

The Dark Side of TESOL

by Kimie Takahashi 高橋君江 in Language on the Move

The latest issue of Cross-Cultural Studies (published by the Center for Cross Cultural Studies, Hyung Hee University, Korea) includes an article about the dark side of TESOL authored by Ingrid Piller, Kimie Takahashi, and Yukinori Watanabe. Based on case studies from … Continue reading →... Read more »

Ingrid Piller, Kimie Takahashi, & Yukinori Watanabe. (2010) The Dark Side of TESOL: The Hidden Costs of the Consumption of English. Cross-Cultural Studies, 183-201. info:/

  • September 12, 2010
  • 03:55 PM

The Extent of Human Genetic Variation

by Michael Long in Phased

David Goldstein (Duke University, United States) and coworkers report steps towards unraveling the extent of human genetic variation, useful for directing medical effort towards genes critical to life. This news feature was written on September 12, 2010.... Read more »

Pelak, K., Shianna, K. V., Ge, D., Maia, J. M., Zhu, M., Smith, J. P., Cirulli, E. T., Fellay, J., Dickson, S. P., Gumbs, C. E.... (2010) The Characterization of Twenty Sequenced Human Genomes. PLoS Genetics, 6(9). DOI: 10.1371/journal.pgen.1001111  

  • September 12, 2010
  • 03:00 PM

Solar Sea Slugs: Part animal, part plant… or not?

by Prof-like Substance in The Spandrel Shop

Original image here. Sea slugs are far more interesting than their name might imply. Aside from being beautiful, they have some unusual ways of making a living. In the case of a few unrelated species, they steal for a living. A handful of sea slugs have found away to make the most of the algae [...]... Read more »

  • September 12, 2010
  • 01:48 PM

Bacteria vesicles - SGM series

by Lab Rat in Lab Rat

The SGM autumn conference is now over - thanks to everyone who tweeted it so people like me could catch up on events without actually going. I've just got two more topics of my own little personal blog-conference to go, and this one is going to be on bacterial vesicles rather than secondary metabolism because it suddenly struck me that I don't actually know much about outer membrane vesicles, and this might be a good opportunity to explore them.So this is the penultimate post in my SGM topic ser........ Read more »

  • September 12, 2010
  • 09:33 AM

You're (Brain Is) So Immature

by Neuroskeptic in Neuroskeptic

How mature are you? Have you ever wanted to find out, with a 5 minute brain scan? Of course you have. And now you can, thanks to a new Science paper, Prediction of Individual Brain Maturity Using fMRI.This is another clever application of the support vector machine (SVM) method, which I've written about previously, most recently regarding "the brain scan to diagnose autism". An SVM is a machine learning algorithm: give it a bunch of data, and it'll find patterns in it.In this case, the input dat........ Read more »

Dosenbach NU, Nardos B, Cohen AL, Fair DA, Power JD, Church JA, Nelson SM, Wig GS, Vogel AC, Lessov-Schlaggar CN.... (2010) Prediction of individual brain maturity using fMRI. Science (New York, N.Y.), 329(5997), 1358-61. PMID: 20829489  

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