Post List

  • November 13, 2009
  • 11:53 AM

New research – stapled proteins

by Avril in Understanding Cancer

There are several news reports out today about a new way of turning off cancer causing proteins. These reports are based on a study in the journal Nature called “Direct Inhibition of the NOTCH transcription factor complex“, you will need to pay to read the article in it’s full technical detail, but there are several [...]... Read more »

Moellering RE, Cornejo M, Davis TN, Del Bianco C, Aster JC, Blacklow SC, Kung AL, Gilliland DG, Verdine GL, & Bradner JE. (2009) Direct inhibition of the NOTCH transcription factor complex. Nature, 462(7270), 182-8. PMID: 19907488  

  • November 13, 2009
  • 11:10 AM

Dyslexia and the Cocktail Party effect

by Mo in Neurophilosophy

IMAGINE sitting in a noisy restaurant, across the table from a friend, and having a conversation with them as you eat your meal. To communicate effectively in this situation, you have to extract the relevant information from the noise in the background, as well as from other voices. To do so, your brain somehow "tags" the predictable, repeating elements of the target signal, such as the pitch of your friend's voice, and segregates them from other signals in the surroundings, which fluctuate rand........ Read more »

  • November 13, 2009
  • 10:25 AM

Wetland Plant of the Week #32

by Johnny in Ecographica

Asterales, the order to which the Asteraceae family belongs, has origins in the Cretaceous period about 100 million years ago and probably experienced diversification during the Oligocene and Miocene. In regards to their evolutionary past, recent research by Tom Viaene (et al) examined the variability of stamen and petal morphologies within the basal asterid families. Through comparisons of the genes that coded for these floral structures, he determined that the early members of the asterid grou........ Read more »

Viaene, T., Vekemans, D., Irish, V., Geeraerts, A., Huysmans, S., Janssens, S., Smets, E., & Geuten, K. (2009) Pistillata--Duplications as a Mode for Floral Diversification in (Basal) Asterids. Molecular Biology and Evolution, 26(11), 2627-2645. DOI: 10.1093/molbev/msp181  

  • November 13, 2009
  • 09:00 AM

Eating speed and calorie control: Weight of the evidence

by Colby in

Recently, a paper by Kokkinos et al. (1) was published on an experiment finding different postprandial Peptide YY and Glucagon-Like Peptide-1 concentration responses with varying eating speed. ¬†This immediately prompted such media headlines as: “Eating Slowly May Help Weight Control,” “Cut Calories by Eating Slowly,” “Eating Slowly Can Help with Weight Loss,” and “Eating Quickly [...]... Read more »

Kokkinos A, le Roux CW, Alexiadou K, Tentolouris N, Vincent RP, Kyriaki D, Perrea D, Ghatei MA, Bloom SR, & Katsilambros N. (2009) Eating Slowly Increases the Postprandial Response of the Anorexigenic Gut Hormones, Peptide YY and Glucagon-Like Peptide-1. The Journal of clinical endocrinology and metabolism. PMID: 19875483  

Gaul, D., Craighead, E., & Mahoney, M. (1975) Relationship between eating rates and obesity. Journal of Consulting and Clinical Psychology, 43(2), 123-125. DOI: 10.1037/h0076522  

Marston AR, London P, Cohen N, & Cooper LM. (1977) In vivo observation of the eating behavior of obese and nonobese subjects. Journal of consulting and clinical psychology, 45(2), 335-6. PMID: 850018  

Andrade AM, Greene GW, & Melanson KJ. (2008) Eating slowly led to decreases in energy intake within meals in healthy women. Journal of the American Dietetic Association, 108(7), 1186-91. PMID: 18589027  

  • November 13, 2009
  • 08:00 AM

Recovery of albatross may depend on removing paint

by Rob Goldstein in Conservation Maven

Scientists estimate that lead paint chips from deteriorating buildings on the Midway Atoll are killing thousands of Laysan albatross juveniles every year. The poor chicks eat the paint chips, which cause toxic effects such as droopwing.

The research team led by Myra Finkelstein developed a demographic model to calculate the benefit that removing the lead paint would have for conserving the species. Their findings published in the journal Animal Conservation run counter to conventional thinkin........ Read more »

  • November 13, 2009
  • 08:00 AM

Genetically engineered heavy metal fans

by sciencebase in Sciencebase Science Blog

The wastewater released from industry often contains high levels of toxic heavy metals, which can kill organisms, damage ecosystems, and accumulate in the foodchain. Electroplating, lead smelting, mining, and countless other processes produce enormous volumes of such wastewater.
In a perfect world, remediation would be powered by a renewable energy supply, there would be no solid [...]Genetically engineered heavy metal fans is a post from: Sciencebase Science Blog
... Read more »

Bhupinder Dhir. (2010) Use of aquatic plants in removing heavy metals from wastewater. Int. J. Environmental Engineering, 2(1/2/3), 185-201. info:/

  • November 13, 2009
  • 07:00 AM

Mobile malware epidemic on the way

by David Bradley in Sciencetext

A mobile malware epidemic could render phone networks useless within two to three years, if public awareness of the issue and network security experts don’t take control out of the hands of hackers.

If you’re intelligent enough to be reading the Sciencetext blog, then it’s unlikely that you’re going to be taken in by an email [...]Post from: David Bradley's Sciencetext Tech TalkMobile malware epidemic on the way
... Read more »

Juil C. Martin, Legand L. Burge III, Joseph I. Gill, Alicia N. Washington, & Marcus Alfred. (2010) Modelling the spread of mobile malware. Int. J. Computer Aided Engineering and Technology, 2(1), 3-14. info:/

  • November 13, 2009
  • 06:29 AM

Confused About Abdominal Bloating? - No More!

by Michael Ash in Nutri-Link Ltd - Clinical Education

Michael Ash BSc(Hons).DO. ND. FDipION reviews the current understanding behind bloating and distension.

The unpleasant symptoms of bloating and abdominal distension are common and bothersome, affecting up to 96% of patients with functional gastrointestinal disorders (such as IBS) and an estimated 30% of the general population. Clear pathophysiologic explanations have been lacking and available treatment options can appear contradictory and ineffective. Treatments will be explored in a follow ........ Read more »

Houghton LA, & Whorwell PJ. (2005) Towards a better understanding of abdominal bloating and distension in functional gastrointestinal disorders. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 17(4), 500-11. PMID: 16078938  

Cremon C, Gargano L, Morselli-Labate AM, Santini D, Cogliandro RF, De Giorgio R, Stanghellini V, Corinaldesi R, & Barbara G. (2009) Mucosal immune activation in irritable bowel syndrome: gender-dependence and association with digestive symptoms. The American journal of gastroenterology, 104(2), 392-400. PMID: 19174797  

  • November 13, 2009
  • 06:00 AM

At Your Service….

by Elements Team in Elements

Part I: The Role of Animals in Public Health

By: Rosemary Stephen, Elements: Environmental Health Intelligence

Pets are very important in the lives of people around the world. Many of us feel we cannot live without our pets; I know I feel that way. I still remember the first cat we ever owned. We got him from [...]... Read more »

Rosemary Stephen. (2009) At Your Service.. Elements: Environmental Health Intelligence. info:/

  • November 13, 2009
  • 06:00 AM

At Your Service…. Part I

by Elements Team in Elements

Part I: The Role of Animals in Public Health

By: Rosemary Stephen, Elements: Environmental Health Intelligence

Pets are very important in the lives of people around the world. Many of us feel we cannot live without our pets; I know I feel that way. I still remember the first cat we ever owned. We got him from [...]... Read more »

Rosemary Stephen. (2009) At Your Service.. Elements: Environmental Health Intelligence. info:/

  • November 13, 2009
  • 04:36 AM

Patients with empathic, attentive doctors recover more quickly from the common cold

by BPS Research Digest in BPS Research Digest

The amount of empathy and attentiveness shown by doctors to their patients really does matter. David Rakel and colleagues have found that patients who rate their doctor as highly empathic recover more quickly from a cold. Their illness is shortened by about a day - the same effect shown by the most promising anti-viral drugs. But a doctor's empathy, unlike the anti-viral, doesn't trigger nausea and diarrhoea.Three hundred and fifty participants were asked to contact the researchers as soon as th........ Read more »

Rakel DP, Hoeft TJ, Barrett BP, Chewning BA, Craig BM, & Niu M. (2009) Practitioner empathy and the duration of the common cold. Family medicine, 41(7), 494-501. PMID: 19582635  

  • November 13, 2009
  • 12:18 AM

Friday Weird Science: Oxytocin and the Big O

by Evil Monkey in Neurotopia

Rounding out Sci's first week of the Great Oxytocin Posting of 2009 (oh yes, there will be two weeks of this, hang tight), we've gotta do something weird. And luckily for everyone, oxytocin does lend itself to the strange types of studies. Like multi-orgasmic studies. Complete with measurements of anal contraction. You know you wanna volunteer for this one.

And luckily for all of you, Sci is the one doing the reading and the retelling of this study. Because reading the methods for this one........ Read more »

  • November 13, 2009
  • 12:00 AM

Monkey business, or is my uncle also my Dad?

by Grant Jacobs in Code for life

Marmoset monkeys and germline chimerism can lead to odd parentage.... Read more »

Ross, C., French, J., & Orti, G. (2007) Germ-line chimerism and paternal care in marmosets (Callithrix kuhlii). Proceedings of the National Academy of Sciences, 104(15), 6278-6282. DOI: 10.1073/pnas.0607426104  

  • November 12, 2009
  • 11:58 PM

Early(!) Sleep Enhances Learning by Observation

by Daniel Hawes in Ingenious Monkey | 20-two-5

A new study in PNAS looks at how observation learning is affected by sleep and - more importantly - the relative immediacy of sleep...... Read more »

Van Der Werf YD, Van Der Helm E, Schoonheim MM, Ridderikhoff A, & Van Someren EJ. (2009) Learning by observation requires an early sleep window. Proceedings of the National Academy of Sciences of the United States of America, 106(45), 18926-18930. PMID: 19884499  

  • November 12, 2009
  • 05:31 PM

The long-term effects of day-care

by Dave Munger in Cognitive Daily

When we were getting ready to have our first child, I decided that I would quit my job, work out of home as a freelancer, and take care of our baby while Greta finished graduate school.

That worked well for about two years, but by the time Nora was born, we decided to hire a part-time nanny so I could finish a degree of my own. When Nora was one and Greta and I were starting new jobs in a new state, both kids entered full-time day care, and that was our child-care arrangement until they starte........ Read more »

Belsky, J., Vandell, D., Burchinal, M., Clarke-Stewart, K., McCartney, K., & Owen, M. (2007) Are There Long-Term Effects of Early Child Care?. Child Development, 78(2), 681-701. DOI: 10.1111/j.1467-8624.2007.01021.x  

  • November 12, 2009
  • 02:58 PM

Cell Phones and Cancer?

by Ryan in Evidence-Based Public Health

CNN has a story about the link between cell phone usage and tumors. Unfortunately, the article tends towards the sensational, and doesn't cite the many recent studies that have failed to find a link between cell phone use and cancer.... Read more »

Ahlbom A, Feychting M, Green A, Kheifets L, Savitz DA, Swerdlow AJ, & ICNIRP (International Commission for Non-Ionizing Radiation Protection) Standing Committee on Epidemiology. (2009) Epidemiologic evidence on mobile phones and tumor risk: a review. Epidemiology (Cambridge, Mass.), 20(5), 639-52. PMID: 19593153  

  • November 12, 2009
  • 02:53 PM

Might as Well be Water on the Sun

by Invader Xan in Supernova Condensate

Water is all the rage. It gets mentioned in every single high profile space mission of late. Searching for water on Mars, water inside Europa, water in the atmospheres of exoplanets. Going to the Moon? Don’t forget to check for water! All with good reason, of course. Being made of 72.8% water, it’s rather important that wherever we might go in the Universe, we have a ready supply of it. But water’s been found in some surprising places.... Read more »

Wallace L, Bernath P, Livingston W, Hinkle K, Busler J, Guo B, & Zhang K. (1995) Water on the sun. Science (New York, N.Y.), 268(5214), 1155-8. PMID: 7761830  

  • November 12, 2009
  • 02:36 PM

Emotions and self-regulation in chronic pain

by Bronwyn Thompson in Healthskills: Skills for Healthy Living

I posted about the reciprocal effect of emotions on goal content and today I want to look a little further into this.
A profound statement in the paper by Hamilton, Karoly & Kitzman is this: ‘If emotional well-being influences the selection and the valuation of a particular goal, then it is likely that the relationship between [...]... Read more »

Hamilton, N., Karoly, P., & Kitzman, H. (2004) Self-Regulation and Chronic Pain:The Role of Emotion. Cognitive Therapy and Research, 28(5), 559-576. DOI: 10.1023/B:COTR.0000045565.88145.76  

  • November 12, 2009
  • 11:50 AM

Sprucing Up Your Garden with Carbon Nanotubes

by Michael Long in Phased

Alexandru Biris (University of Arkansas) and coworkers observe that carbon nanotubes can help tomato plants grow. This news feature was written on November 12, 2009.... Read more »

  • November 12, 2009
  • 10:50 AM

On immunity to Swine-origin Influenza Virus (SOIV)

by iayork in Mystery Rays from Outer Space

Persons who were born before 1957 had a reduced risk of infection …¬† Persons who were born between 1957 and 1975 were at intermediate risk for infection. 1

In Ontario, people over 53 years old had about 1/6 the chance2 of getting the new H1N1; the those between about 33 and 53 had a [...]... Read more »

David N. Fisman, Rachel Savage, Jonathan Gubbay, Camille Achonu, Holy Akwar, David J. Farrell, Natasha S. Crowcroft, & Phil Jackson. (2009) Older Age and a Reduced Likelihood of 2009 H1N1 Virus Infection. The New England Journal of Medicine, 2000-20001. info:/

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