Post List

  • March 10, 2009
  • 09:00 AM
  • 1,788 views

SIMONE takes control of corporate email

by David Bradley in Sciencetext

Employees are spending increasing amounts of time handling email, time that may detract from their primary role within an organization. As such, business researchers have repeatedly raised concerns about email overload, constant interruptions, technology addiction, attention deficiency and productivity loss. And that doesn’t take into account social media and social bookmarking sites like twitter, facebook, [...]Post from: David Bradley's Sciencetext Tips and Tricks

SIMONE takes control o........ Read more »

Ashish Gupta, & Ramesh Sharda. (2008) SIMONE: A Simulator for Interruptions and Message Overload in Network Environments. Int. J. Simulation and Process Modelling, 4(3/4), 237-247.

  • March 10, 2009
  • 07:46 AM
  • 1,557 views

Abilify, Depression, and the Memory Hole

by CL Psych in Clinical Psychology & Psychiatry

The Primary Care Companion to the Journal of Clinical Psychiatry has a piece on Abilify for depression that illustrates many of psychiatry's woes. Full text of the article is here. The journal published an article titled "Examining the efficacy of adjunctive aripiprazole in major depressive disorder: A pooled analysis of two studies." The paper combines data from two previously published studies which examined the addition of Abilify to existing antidepressant treatment (1, 2). One of psychi........ Read more »

Thase ME, Trivedi MH, Nelson JC, Fava M, Swanink R, Tran Q, Pikalov A, Yang H, Carlson BX, Marcus RN.... (2008) Examining the efficacy of adjunctive aripiprazole in major depressive disorder: A pooled analysis of 2 studies. Primary Care Companion to the Journal of Clinical Psychiatry, 440-447.

  • March 10, 2009
  • 01:50 AM
  • 2,516 views

Chocolate Craving

by Dr Shock in Dr Shock MD PhD

Research suggests that up to 97% of women and 68% of men experience food cravings. Chocolate is the most common one of the craved foods, typically high calorie.

A number of situations have been shown to experimentally increase cravings of chocolate consumption. For example,chocolate abstinence, stress and exposure to chocolate cues increase urges to eat chocolate. [...]... Read more »

  • March 10, 2009
  • 12:00 AM
  • 1,181 views

Believer Brains Different from Non-Believer Brains?

by Neural Outlaw in Neural Interface

As mentioned in an earlier blog about my research interests, my general (research) focus relates to issues of mental health (schizophrenic symptoms in particular) and I hope to build my career in that area. A side-interest of mine relates to neuropsychological and neurophysiological effects of religion. I am by no means any kind of expert on the matter nor am I intimately familiar with the breadth of literature that already exists on the subject. I like to briefly explore this issue for my own u........ Read more »

Michael Inzlicht, Ian McGregor, Jacob B. Hirsh, & Kyle Nash. (2009) Neural Markers of Religious Conviction. Psychological Science, 20(3), 385-392. DOI: 10.1111/j.1467-9280.2009.02305.x  

  • March 10, 2009
  • 12:00 AM
  • 736 views

On Excel-Damaged Genes

by Luke Jostins in Genetic Inference

In the half an hour I have before an afternoon seminar, I thought I’d share an interesting and amusing paper that came out a few years back. It is entitled "Mistaken Identifiers: Gene name errors can be introduced inadvertently when using Excel in bioinformatics" [...]... Read more »

Barry R Zeeberg, Joseph Riss, David W Kane, Kimberly J Bussey, Edward Uchio, W Marston Linehan, J Carl Barrett, & John N Weinstein. (2004) Mistaken Identifiers: Gene name errors can be introduced inadvertently when using Excel in bioinformatics. BMC Bioinformatics, 5(1), 80. DOI: 10.1186/1471-2105-5-80  

  • March 10, 2009
  • 12:00 AM
  • 1,746 views

Baby, it's cold outside

by Iddo Friedberg in Byte Size Biology

Anyone who failed to empty their milk carton on time knows that some microbes do eat (and therefore grow) at near-zero temperatures. Nevertheless, we don’t know about cold bacteria, even though as we have seen, most of the real estate on Earth is cold. Also, if we were to find life in the solar system, it would probably be found on the cold moons of Jupiter and Saturn, in the Martian ice caps, or in subsurface Martian ice. The first step to understand how life might exist there is, to un........ Read more »

  • March 10, 2009
  • 12:00 AM
  • 2,152 views

Chimpanzee plans for the future

by Bjørn Østman in Pleiotropy

Santino is a thirty year old male chimpanzee at Furuvik Zoo in Sweden. For the last decade he has been collecting stones before the zoo opens, stashing them in around his enclosure, and then when the visitors arrive, has been throwing the rocks at them - though, thankfully, he apparently has a poor aim.... Read more »

  • March 9, 2009
  • 11:03 PM
  • 1,774 views

The factor structure of Religiosity and its neural substrates

by sandygautam in The Mouse Trap

A new article in PNAS by Grafman et al, argues that Religiosity can be broken down into three factors and the underlying machinery that these factors use are basic Theory Of Mind (ToM) circuitry, thus substantiating the claim that religion occurred as a byproduct of basic ToM related adaptations, although not ruling out that once established Religion may have provided adaptive advantage.

First a detour. I am more interested in this study as I had once claimed that Schizophrenics were more reli........ Read more »

* Dimitrios Kapogiannis,, * Aron K. Barbey,, * Michael Su,, * Giovanna Zamboni,, * Frank Krueger,, & * and Jordan Grafman. (2009) Cognitive and neural foundations of religious belief. PNAS. DOI: http://www.pnas.org/content/early/2009/03/06/0811717106.abstract?sid  

  • March 9, 2009
  • 08:28 PM
  • 1,454 views

A dead gene comes back to life in humans

by Greg Laden in Greg Laden's Blog

Why is there "junk DNA"? What is Junk DNA? What is a Pseudogene? What is Gene Duplication?

Goodness, you certainly do have a lot of questions. And some of them can be answered, or at least addressed, on examination of a very interesting new paper recently published about a gene that became a useless "pseudogene" a very long time ago and has recently been revived by evolution to serve once again as an active member of the community we know of as the genome. In humans. Read the rest of ........ Read more »

Cemalettin Bekpen, Tomas Marques-Bonet, Can Alkan, Francesca Antonacci, Maria Bruna Leogrande, Mario Ventura, Jeffrey M. Kidd, Priscillia Siswara, Jonathan C. Howard, & Evan E. Eichler. (2009) Death and Resurrection of the Human IRGM Gene. PLoS Genetics, 5(3). DOI: 10.1371/journal.pgen.1000403  

  • March 9, 2009
  • 05:02 PM
  • 1,672 views

Brain mechanisms of Freudian repression

by Mo in Neurophilosophy

More than 100 years ago, Sigmund Freud, the father of psychoanalysis, proposed a mechanism called repression, whereby desires and impulses are actively pushed into the unconscious mind. For Freud, repression was a defence mechanism - the repressed memories are often traumatic in nature, but, although hidden, they continue to exert an effect on behaviour.

Many of Freud's theories have long since been discredited, but they remain influential to this day. Repression in particular has proven to be ........ Read more »

S. Hanslmayr, P. Leipold, B. Pastotter, & K.-H. Bauml. (2009) Anticipatory Signatures of Voluntary Memory Suppression. Journal of Neuroscience, 29(9), 2742-2747. DOI: 10.1523/JNEUROSCI.4703-08.2009  

  • March 9, 2009
  • 04:22 PM
  • 1,079 views

The Battle for Broca's area

by Greg Hickok in Talking Brains

David commented previously on Grodzinsky and Santi's (2008) TICS paper on the function of Broca's area. Justifiably in my view, David expressed his disappointment that an obviously multi-functional region was being linked to a single function, syntactic movement. In addition, a recent reply to the paper in TICS by Roel Willems and Peter Hagoort (2009) highlighted the possible role of Broca's area in semantic processing, an issue that was not addressed at all in the Grodzinsky and Santi paper. ........ Read more »

Y GRODZINSKY, & A SANTI. (2008) The battle for Broca’s region. Trends in Cognitive Sciences, 12(12), 474-480. DOI: 10.1016/j.tics.2008.09.001  

  • March 9, 2009
  • 01:01 PM
  • 2,184 views

Magma beneath Socorro, New Mexico

by Kim Hannula in All of My Faults Are Stress Related

I had no idea there was magma beneath Socorro, New Mexico. When I read about it in this month's Geology, my first reaction was OMG WE'RE GONNA DIE!. (I've been occasionally using the electron microprobe at New Mexico Tech to look at rocks that were metamorphosed around a 380-million-year-old granite. I had no idea that the same kinds of processes were going on, right then, beneath my feet.)

The magma body is 19 km deep in the crust. That's about 2/3 of the way to the mantle - pretty far from t........ Read more »

  • March 9, 2009
  • 12:48 PM
  • 1,557 views

when NOT to MANOVA

by jebyrnes in I'm a chordata, urochordata!

And now its time for a multivariate stats geek out.

The statistics that we use determine the inferences we draw from our data. The more statistical tools you learn to use, the more likely you are likely to slip on a loose bit of data, and stab yourself in the eyeball with your swiss-army-knife of [...]... Read more »

H. J. Keselman, C. J. Huberty, L. M. Lix, S. Olejnik, R. A. Cribbie, B. Donahue, R. K. Kowalchuk, L. L. Lowman, M. D. Petoskey, J. C. Keselman.... (1998) Statistical Practices of Educational Researchers: An Analysis of their ANOVA, MANOVA, and ANCOVA Analyses. Review of Educational Research, 68(3), 350-386. DOI: 10.3102/00346543068003350  

  • March 9, 2009
  • 12:00 PM
  • 1,211 views

Hello, I'm Evaluating You

by David DiSalvo in Neuronarrative

I’m intrigued by a study that came out recently in Nature Neuroscience on the neural circuitry of first impressions. Researchers from New York University and Harvard joined forces to identify what neural systems are in play when we first meet someone.

This has been the subject of quite a lot of observational research (some of which was brought to light in Malcolm Gladwell’s book, Blink), but this study was designed to delve deeper.
... Read more »

Schiller, D., Freeman, J., Mitchell, J., Uleman, J., & Phelps, E. (2009) A neural mechanism of first impressions. Nature Neuroscience. DOI: 10.1038/nn.2278  

  • March 9, 2009
  • 11:20 AM
  • 794 views

For now, forget biofuels in reserves

by Katie Kline in EcoTone

Ethanol as the next generation of alternative fuels has stirred significant controversy. While some tout its lower-than-gasoline greenhouse-gas emissions and its usefulness in creating carbon sinks in its agricultural fields, many other ecologists call ethanol production the most inefficient of alternative fuel options. Even the most optimistic scenarios still show that using current technologies, it [...]... Read more »

Gervasio Piñeiro, Esteban G. Jobbágy, Justin Baker, Brian C. Murray, & Robert B. Jackson. (2009) Set-asides can be better climate investment than corn ethanol. Ecological Applications, 19(2), 277-282. DOI: 10.1890/08-0645.1  

  • March 9, 2009
  • 10:53 AM
  • 1,434 views

Evidence for heightened Agency in Schizophrenia

by sandygautam in The Mouse Trap

I have been maintaining that Autism and Schizophrenia are opposites on a continuum and one dimension on which they differ is Agency , with autistics attributing too less agency to themselves (and others), while schizophrenics attributing too much agency to themselves (and others).

The case for people with ASD is fairly settled. They have deficits in theory Of Mind (ToM) and one mechanism by which this deficit seems to arise is via their attributing less agency to themselves as well as others. ........ Read more »

Haggard P, Martin F, Taylor-Clarke M, Jeannerod M, Franck N. (2003) Awareness of action in schizophrenia. Neuroreport, 14(7), 1081-1085. DOI: http://www.neuroreport.com/pt/re/neuroreport/abstract.00001756-200305230-00035.htm;jsessionid  

  • March 9, 2009
  • 10:14 AM
  • 1,740 views

Clozapine Response and Lipids: An Intriguing Correlation

by j7uy5 in The Corpus Callosum

(comic from kxcd)

This post

will discuss some findings about the factors that

are correlated to clinical response to clozapine

(Clozaril® , FazaClo® ).  

Clozapine is a drug used to treat psychosis.  It usually is

used for persons with schizophrenia; sometimes it is used for persons

with schizoaffective disorder, bipolar disorder, or psychosis

associated with Parkinson disease.  

Clozapine was developed in the 1960's.  It was the first

so-called atypical ant........ Read more »

Ric M. Procyshyn, PhD, Kishor M. Wasan, PhD, Allen E. Thornton, PhD, Alasdair M. Barr, PhD, Eric Y.H. Chen, MD, Edith Pomarol-Clotet, MD, Emmanuel Stip, MD, Richard Williams, MB, G. William MacEwan, MD, C. Laird Birmingham, MD, William G. Honer, MD, and f. (2007) Changes in serum lipids, independent of weight, are associated with changes in symptoms during long-term clozapine treatment. J Psychiatry Neurosci, 32(5), 331-338. DOI: 17823649  

Ric M. Procyshyn, PhD, Kishor M. Wasan, PhD, Allen E. Thornton, PhD, Alasdair M. Barr, PhD, Eric Y.H. Chen, MD, Edith Pomarol-Clotet, MD, Emmanuel Stip, MD, Richard Williams, MB, G. William MacEwan, MD, C. Laird Birmingham, MD, William G. Honer, MD, and f. (2007) Changes in serum lipids, independent of weight, are associated with changes in symptoms during long-term clozapine treatment. J Psychiatry Neurosci, 32(5), 331-338. DOI: 17823649  

Ric M. Procyshyn, PhD, Kishor M. Wasan, PhD, Allen E. Thornton, PhD, Alasdair M. Barr, PhD, Eric Y.H. Chen, MD, Edith Pomarol-Clotet, MD, Emmanuel Stip, MD, Richard Williams, MB, G. William MacEwan, MD, C. Laird Birmingham, MD, William G. Honer, MD, and f. (2007) Changes in serum lipids, independent of weight, are associated with changes in symptoms during long-term clozapine treatment. J Psychiatry Neurosci, 32(5), 331-338. DOI: 17823649  

Ric M. Procyshyn, PhD, Kishor M. Wasan, PhD, Allen E. Thornton, PhD, Alasdair M. Barr, PhD, Eric Y.H. Chen, MD, Edith Pomarol-Clotet, MD, Emmanuel Stip, MD, Richard Williams, MB, G. William MacEwan, MD, C. Laird Birmingham, MD, William G. Honer, MD, and f. (2007) Changes in serum lipids, independent of weight, are associated with changes in symptoms during long-term clozapine treatment. J Psychiatry Neurosci, 32(5), 331-338. DOI: 17823649  

Ric M. Procyshyn, PhD, Kishor M. Wasan, PhD, Allen E. Thornton, PhD, Alasdair M. Barr, PhD, Eric Y.H. Chen, MD, Edith Pomarol-Clotet, MD, Emmanuel Stip, MD, Richard Williams, MB, G. William MacEwan, MD, C. Laird Birmingham, MD, William G. Honer, MD, and f. (2007) Changes in serum lipids, independent of weight, are associated with changes in symptoms during long-term clozapine treatment. J Psychiatry Neurosci, 32(5), 331-338. DOI: 17823649  

  • March 9, 2009
  • 10:00 AM
  • 1,524 views

Polio among the Amish

by vrr in virology blog

The last outbreak of poliomyelitis in the United States occurred in 1979, when a type 1 strain imported from the Netherlands caused 13 paralytic cases among unvaccinated Amish communities in three states. Twenty years later, use of the live, attenuated poliovirus vaccine (OPV) was discontinued in the United States, and was replaced with the inactivated [...]... Read more »

James P. Alexander, Kristen Ehresmann, Jane Seward, Gary Wax, Kathleen Harriman, Susan Fuller, Elizabeth A. Cebelinski, Qi Chen, Jaume Jorba, Olen M. Kew.... (2009) Transmission of Imported Vaccine‐Derived Poliovirus in an Undervaccinated Community in Minnesota. The Journal of Infectious Diseases, 199(3), 391-397. DOI: 10.1086/596052  

  • March 9, 2009
  • 09:38 AM
  • 987 views

Autism, neurofeedback , and the processing of novel distracters

by Nestor Lopez-Duran in Translating Autism

Children with autism show increased reaction time and unique brain wave patters during tasks that include novel distracters.A review of: Estate Sokhadze, Joshua Baruth, Allan Tasman, Lonnie Sears, Grace Mathai, Ayman El-Baz, Manuel F. Casanova (2009). Event-related Potential Study of Novelty Processing Abnormalities in Autism Applied Psychophysiology and Biofeedback, 34 (1), 37-51 DOI: 10.1007/... Read more »

Estate Sokhadze, Joshua Baruth, Allan Tasman, Lonnie Sears, Grace Mathai, Ayman El-Baz, & Manuel F. Casanova. (2009) Event-related Potential Study of Novelty Processing Abnormalities in Autism. Applied Psychophysiology and Biofeedback, 34(1), 37-51. DOI: 10.1007/s10484-009-9074-5  

  • March 9, 2009
  • 09:01 AM
  • 1,698 views

Meta Tags and Web 3.0

by David Bradley in Sciencetext

In 2008, Google spidered its trillionth web page. That sounds impressive, but as LISNews, the Librarian And Information Science News, recently pointed out that figure represents but a tiny fraction of the information on the web. How so, you ask? Well, think of all those ecommerce databases, library catalogs, transport system fares and timetables… There [...]Post from: David Bradley's Sciencetext Tips and Tricks

Meta Tags and Web 3.0... Read more »

Badawia M. Albassuny. (2008) Automatic metadata generation applications: a survey study . Int. J. Metadata, Semantics and Ontologies, 3(4), 260-282.

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