Across the ~3 billion or so base pairs in the human genome there’s a fair amount of variation. That variation can be partitioned into different classes, somewhat artificial constructions of human categorization systems, but nevertheless mapping on to real demographic or life history events of particular importance. Some of the variation is specific to populations, [...]... Read more »
The International HapMap 3 Consortium. (2010) Integrating common and rare genetic variation in diverse human populations. Nature. info:/10.1038/nature09298
Props to my colleague Lindsay Beyerstein for this great catch yesterday: Tea Party favorite Sharron Angle's campaign received a donation from someone who listed her employer as "husband" and her occupation as "slave." Maybe it's just a joke (boring). Or maybe this couple is in one of those Christian "submitted wife" relationships (unlikely, given that "slave" isn't the sort of rhetoric that culture promotes). But maybe this is an "out" dominant/submissive couple. That shouldn't be a ........ Read more »
Benjamin Edelman. (2009) Red Light States: Who Buys Online Adult Entertainment?. Journal of Economic Perspectives, 23(1). DOI: 10.1257/jep.23.1.209
Zhong CB, & Liljenquist K. (2006) Washing away your sins: threatened morality and physical cleansing. Science (New York, N.Y.), 313(5792), 1451-2. PMID: 16960010
Schnall S, Benton J, & Harvey S. (2008) With a clean conscience: cleanliness reduces the severity of moral judgments. Psychological science : a journal of the American Psychological Society / APS, 19(12), 1219-22. PMID: 19121126
... Read more »
"LKB1 is a master kinase" What a great subheader in a paper last year by Reuben Shaw (journal link below). Liver kinase B1 (LKB1) first got my attention at the AACR lung cancer meeting in San Diego earlier this year,...... Read more »
Shaw RJ. (2009) LKB1 and AMP-activated protein kinase control of mTOR signalling and growth. Acta physiologica (Oxford, England), 196(1), 65-80. PMID: 19245654
Shackelford DB, & Shaw RJ. (2009) The LKB1-AMPK pathway: metabolism and growth control in tumour suppression. Nature reviews. Cancer, 9(8), 563-75. PMID: 19629071
Hi there! Been a long time eh? Not sure what happened there, but I blame Harry. Somehow, somewhere he was involved. So let’s just jump right into it Stress. Your reason for not calling your mother, a graduate student’s excuse for overeating, not sleeping, forgetting to hand in an abstract, walking into walls and lying [...]... Read more »
Bruce S. McEwen. (2007) Physiology and Neurobiology of Stress and Adaptation: Central Role of the Brain. Physiological Reviews, 873-904. info:/
It is summer, July already! Vacation time for kids and the people that love them. Though many years past, I recall fondly one of our first family trips to the Black Hills of South Dakota. While en route, we stopped in the Badlands National Park. Though the Badlands might appear a barren, treeless desert (and [...]... Read more »
Slobodchikoff CN, Paseka A, & Verdolin JL. (2009) Prairie dog alarm calls encode labels about predator colors. Animal cognition, 12(3), 435-9. PMID: 19116730
Eating food is a wonderful activity. Without it, you’d die.
But have you ever gone overboard? Got to the end of a meal and thought:
“I ate too much.”
In the natural world, we’re so used to thinking of food as scarce for animals that we don’t often think about issues associated with animals that eat and eat and eat until they do not eat any more. It probably is fairly hard to hit that satiation point for many species.
On the other hand, some species are well known for infrequent bu........ Read more »
Pruitt JN, & Krauel JJ. (2010) The adaptive value of gluttony: predators mediate the life history trade-offs of satiation threshold. Journal of Evolutionary Biology. DOI: 10.1111/j.1420-9101.2010.02070.x
Back in 2007, Paul Ohm, a law professor in the University of Colorado law school, guest-blogged in a popular law blog called The Volokh Conspiracy. He guest-blogged for one week about two of his papers: "The Analog Hole and the Price of Music: An Empirical Study" and "The Myth of the Superuser: Fear, Risk, and Harm Online." Being more computer-savvy than the average law professor (he has a B.Sc. in Computer Science) he wrote a script which checked the number of abstract views and downloads of hi........ Read more »
Paul Ohm. (2007) Do Blogs Influence SSRN Downloads? Empirically Testing the Volokh and Slashdot Effects. U of Colorado Law Legal Studies Research Paper . info:other/
What have people been talking about this week in high energy physics, astrophysics, gravitation, general relativity and quantum gravity?... Read more »
Lisa J. Kewley, David Rupke, H. Jabran Zahid, Margaret J. Geller, & Elizabeth J. Barton. (2010) Metallicity Gradients and Gas Flows in Galaxy Pairs. arXiv. DOI: 1008.2204
Mayer L, Kazantzidis S, Escala A, & Callegari S. (2010) Direct formation of supermassive black holes via multi-scale gas inflows in galaxy mergers. Nature, 466(7310), 1082-4. PMID: 20740009
J. K. Webb, J. A. King, M. T. Murphy, V. V. Flambaum, R. F. Carswell, & M. B. Bainbridge. (2010) Evidence for spatial variation of the fine structure constant. arXiv. arXiv: 1008.3907v1
Harold V. Parks, & James E. Faller. (2010) A Simple Pendulum Determination of the Gravitational Constant. Phys. Rev. Let. arXiv: 1008.3203v2
Graphene is one of the hottest research areas in nanotechnology, and it may seem slightly surprising it took me a month to write my first blog post on the topic. That moment has now come, with the advance publication of a Nature paper that presents highly attractive graphene transistor, even though in my humble opinion [...]... Read more »
Liao, L., Lin, Y.-C., Bao, M., Cheng, R., Bai, J., Liu, Y., Qu, Y., Wang, K. L., Huang, Y., & Duan, X. (2010) High-speed graphene transistors with a self-aligned nanowire gate. Nature. DOI: 10.1038/nature09405
One of the things I sometimes find myself writing about is the “bad” language used by physicists. Sometimes we say Riemannian when we really should say psuedo-Riemannian, sometimes we call something a metric when it really is a line element – the kind of nitpicky pet-peeves that practically everyone has about literature in their field. Today, I’m going to be talking about the bad language in physics in a totally different context however.... Read more »
ALPER ÜNGÖR, & ALLA SHEFFER. (2002) PITCHING TENTS IN SPACE-TIME: MESH GENERATION FOR DISCONTINUOUS GALERKIN METHOD. International Journal of Foundations of Computer Science , 13(2). info:/10.1142/S0129054102001059
I recently came across a very interesting study published in Circulation in 2001. In it, authors Darren McGuire and colleagues perform the 30-year follow-up on a group of 5 men who had taken part in the Dallas Bed Rest and Training Study (DBRTS). The DBRTS took place in 1966, when all 5 men were healthy 20 year-olds. They were assessed extensively at 3 different time points: baseline, following 3 months of bed rest, and following 8 weeks of physical training. In 1996 these same 5 men were as........ Read more »
McGuire DK, Levine BD, Williamson JW, Snell PG, Blomqvist CG, Saltin B, & Mitchell JH. (2001) A 30-year follow-up of the Dallas Bedrest and Training Study: I. Effect of age on the cardiovascular response to exercise. Circulation, 104(12), 1350-7. PMID: 11560849
Nobody’s against cleaner, greener neighborhoods. But some social scientists have worried that cleaning up could end up clearing out the poor residents who often live around polluted sites. Now, a study from Portland, Oregon looks for a link between gentrification and environmental clean-up.
Researchers have long documented the impact of LULUs — “locally undesirable land […] Read More »... Read more »
Eckerd, Adam. (2010) Cleaning Up Without Clearing Out? A Spatial Assessment of Environmental Gentrification. Urban Affairs Review. DOI: 10.1177/1078087410379720
From Critical Social Policy Over recent years there has been concern about the future sustainability of UK pensions mainly linked with the increase in life expectancy of the general population. The government and pensions industry face the difficult challenge of satisfying two potentially contrasting demands: to ensure that government pension spending remains stable and also [...]... Read more »
Liam Foster. (2010) Towards a new political economy of pensions? The implications for women. Critical Social Policy, 30(1), 27-47. info:/10.1177/0261018309350807
“You’re probably wondering why I’m here”, were the first words of Edward Marcotte’s talk at the SDB meeting last month. After all, he was about to speak about systems biology in a session on organogenesis. What followed was not only a new way to identify genes involved in developmental processes, but also a perfect example [...]... Read more »
Kriston L. McGary, Tae Joo Park, John O. Woods, Hye Ji Cha, John B. Wallingford, & Edward M. Marcotte. (2010) Systematic discovery of nonobvious human disease models through orthologous phenotypes. PNAS. DOI: 10.1073/pnas.0910200107
As mentioned in the previous post, last week I was attending the Information Interaction in Context Symposium held in New Brunswick, USA.
At the poster session, I and my student Justin Wong (left in the photo) from the University of Toronto, presented our ongoing work on the development and evaluation of a context-aware information retrieval system for blog authors called CONTEXT.... Read more »
Gruzd, A. and Wong, J. (2010) Blogging with CONTEXT: a context-aware information retrieval system for bloggers. In Proceeding of the Third Symposium on information interaction in Context, 289-292. info:/10.1145/1840784.1840827
Coevolution is a really cool evolutionary process in which a genetically driven change in the phenotype of one species is responsible for a change in the evolutionary pressures on a second species. The term was coined in the 1960s, and the concept (formalized by Janzen in 1980) is receiving an increasing interest ever since. One [...]... Read more »
James W Demastes, & Mark Hafner. (1993) Cospeciation of Pocket Gophers (Geomys) and Their Chewing Lice (Geomydoecus) . Journal of Mammalogy, 74(3). DOI: 10.2307/1382271
Yves Desdevises, Serge Morand, Olivier Jousson, & Pierre Legendre. (2002) Coevolution between Lamellodiscus (Monogenea: Diplectanidae) and Sparidae (Teleostei): The Study Of a Complex Host-Parasite System. Evolution, 14(12). DOI: 10.1111/j.0014-3820.2002.tb00171.x
Strauss SY, Sahli H, & Conner JK. (2005) Toward a more trait-centered approach to diffuse (co)evolution. The New phytologist, 165(1), 81-89. PMID: 15720623
Lynn Swafford, & Jason E Bond. (2010) Failure to cospeciate: an unsorted tale of millipedes and mites. Biological Journal of the Linnean Society. info:/10.1111/j.1095-8312.2010.01499.x
In the September issue of GSA Today, you can find our article on The Internet as a resource and support network for diverse geoscientists. Where do we go from here? Continue reading →... Read more »
Jefferson, A.J., Hannula, K.A., Campbell, P.B., & Franks, S.E. (2010) The Internet as a resource and support network for diverse geoscientists. GSA Today, 20(9), 59-61. info:/10.1130/GSATG91GW.1
The cover article for last week's issue of Nature promised to be the last word in a long-running scientific argument over the evolution of cooperation—but it really just rejiggers the terms of the debate. Instead of solving the problem of how cooperative behavior can evolve, the new paper presents a model of maternal enslavement [$a]. These are not, it turns out, quite the same thing.
Group selection versus kin selection
Let's start with some background. Unselfish, cooperative behavior has l........ Read more »
Promoting microbial degradation of oil has been one of the main arguments in favor of dispersant use. Interestingly, the PWSRCAC review (covering literature from 1997-2008) did not identify any recent study that explicitly found dispersant use enhancing the biodegradation of oil. Actually, ~50% of studies found that chemical additives inhibited microbial degradation and the other half . . . → Read More: Dispersants! Part III: Do dispersants really promote degradation of oil?... Read more »
Venosa AD, & Holder EL. (2007) Biodegradability of dispersed crude oil at two different temperatures. Marine pollution bulletin, 54(5), 545-53. PMID: 17316707
Yoshida A, Nomura H, Toyoda K, Nishino T, Seo Y, Yamada M, Nishimura M, Wada M, Okamoto K, Shibata A.... (2006) Microbial responses using denaturing gradient gel electrophoresis to oil and chemical dispersant in enclosed ecosystems. Marine pollution bulletin, 52(1), 89-95. PMID: 16202430
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