Elizabeth Jares-Erijman (Universidad de Buenos Aires,
Argentina) and coworkers have developed a non-perturbing protocol
for inducing and monitoring the formation of amyloid aggregates,
implicated in a number of neurodegenerative conditions,
in living cells.
This news feature was written on June 18, 2009.... Read more »
Roberti, M. J., Morgan, M., Menéndez, G., Pietrasanta, L. I., Jovin, T. M., & Jares-Erijman, E. A. (2009) Quantum Dots As Ultrasensitive Nanoactuators and Sensors of Amyloid Aggregation in Live Cells. Journal of the American Chemical Society, 131(23), 8102-8107. DOI: 10.1021/ja900225w
It is great to see the eminent french football philosopher and scientist Eric Cantona back in his adopted hometown of Manchester. As well as visiting in person during production of the latest Ken Loach film (on the famous Keppel Road, Chorlton) and appearing at the premiere, Eric is currently gracing silver screens in cinemas all [...]... Read more »
[Originally posted January, 2007]
Nearly all video games that offer a first-person perspective -- where the view on-screen simulates what a real person would see as she navigates through the virtual environment -- also include a virtual map to help in navigation. Even my favorite golf game has one. Such maps can be indispensable, but they also invite a question -- should the map rotate to align with the player's viewing angle, or should they remain at a constant orientation?
Aligning the map ........ Read more »
Gunzelmann, G., & Anderson, J.R. (2006) Location matters: Why target location impacts performance in orientation tasks. Memory , 34(1), 41-59.
Much of the scientific research in to the effects of video games on players’ behaviour concludes that violent games promote aggression. Gamers (including myself) often dismiss these findings, resulting as they nearly always do from poorly designed studies. One infamous experiment used the length of time a person held an air horn down before and [...]... Read more »
Gentile, D., Anderson, C., Yukawa, S., Ihori, N., Saleem, M., Lim Kam Ming, ., Shibuya, A., Liau, A., Khoo, A., Bushman, B.... (2009) The Effects of Prosocial Video Games on Prosocial Behaviors: International Evidence From Correlational, Longitudinal, and Experimental Studies. Personality and Social Psychology Bulletin, 35(6), 752-763. DOI: 10.1177/0146167209333045
First of all, remember that post I wrote on the serotonin theory of depression, and how it was probably wrong? I was right it is at the very least incomplete. Another one bites the dust. It's sad, as we are so desperate to find SOME theory on which we people who like to study depression can hang our hats. But the serotonin one was not to be. Check out the blog coverage. It is incisive. I don't know that we should be THAT hard on the researchers who invented the idea. After all, it was a........ Read more »
If you haven’t yet heard, the Nature Conservancy recently released a report that documented a staggering decline in oyster reefs. According to the report, “Globally, 85% of oyster reefs have been lost, making oyster reefs one of the most severely impacted marine ecosystem on the planet (Shellfish Reefs at Risk, Nature Conservancy, 2009).”
But as oysters [...]... Read more »
RÉGNIER, C., FONTAINE, B., & BOUCHET, P. (2009) Not Knowing, Not Recording, Not Listing: Numerous Unnoticed Mollusk Extinctions. Conservation Biology. DOI: 10.1111/j.1523-1739.2009.01245.x
The growing prevalence of autism worldwide has parents and clinicians searching for effective treatment options. Though not approved by the United States Food and Drug Administration for the treatment of autism, a common class of antidepressants is often prescribed to treat the symptoms of autism in children. The selective serotonin reuptake inhibitors (SSRIs) are among [...]... Read more »
King, B., Hollander, E., Sikich, L., McCracken, J., Scahill, L., Bregman, J., Donnelly, C., Anagnostou, E., Dukes, K., Sullivan, L.... (2009) Lack of Efficacy of Citalopram in Children With Autism Spectrum Disorders and High Levels of Repetitive Behavior: Citalopram Ineffective in Children With Autism. Archives of General Psychiatry, 66(6), 583-590. DOI: 10.1001/archgenpsychiatry.2009.30
SOORYA, L., KIARASHI, J., & HOLLANDER, E. (2008) Psychopharmacologic Interventions for Repetitive Behaviors in Autism Spectrum Disorders. Child and Adolescent Psychiatric Clinics of North America, 17(4), 753-771. DOI: 10.1016/j.chc.2008.06.003
Our weekly compilation of science news for the week of June 14, 2009.... Read more »
Smith, G., Vijaykrishna, D., Bahl, J., Lycett, S., Worobey, M., Pybus, O., Ma, S., Cheung, C., Raghwani, J., Bhatt, S.... (2009) Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic. Nature. DOI: 10.1038/nature08182
Caspi, A. (2003) Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene. Science, 301(5631), 386-389. DOI: 10.1126/science.1083968
Yan, P., Wang, T., Newton, G., Knyushko, T., Xiong, Y., Bigelow, D., Squier, T., & Mayer, M. (2009) A Targeted Releasable Affinity Probe (TRAP) for In Vivo Photocrosslinking. ChemBioChem, 10(9), 1507-1518. DOI: 10.1002/cbic.200900029
Well over a year after Simon Singh's 'libelous' article on Chiropractic was published; with Singh preparing to launch an appeal against Eady's ruling in the preliminary hearing of the result trial; and with the chiropractic profession under siege from a PR nightmare; the British Chiropractic Association have finally decided to release the evidence that they claim backs up their promotion of Chiropractic treatments.
In doing so, they appear to have been deliberately dishonest in their presentat........ Read more »
Cathryn MA Glazener, Jonathan HC Evans, & Daniel KL Cheuk. (2009) Complementary and miscellaneous interventions for nocturnal enuresis in children. Cochrane Database of Systematic Reviews.
Attempts to design websites suited to men or women are misguided because they rely on social stereotypes, according to a recent study. Rather than focusing on gender, the study’s authors suggest that designers should optimize their sites for different character traits: personal autonomy, selfishness, compassion and for whether a person is a hunter or a [...]Post from: David Bradley's Sciencetext Tips and Tricks
Trouble with Sex on the Internet... Read more »
Maureen E. Hupfer, & Brian Detlor. (2009) Sex, gender and self-concept: predicting web shopping site design preferences. Int. J. Electronic Business, 7(3), 217-236.
Sue Storm tries hard to use her favorite force field to counter the 1 kcal/mol barrierEvery once in a while there is a study asking what method X (X = docking, free energy calculations, molecular dynamics, force fields etc.) is good for. Such studies can be useful to take stock of a particular paradigm. So the question that Jonathan Goodman and his group ask in this paper is "Are force fields good for reproducing non-bonded interactions, especially hydrogen bonding, pi-stacking and dispersion?"......... Read more »
Paton, R., & Goodman, J. (2009) Hydrogen Bonding and π-Stacking: How Reliable are Force Fields? A Critical Evaluation of Force Field Descriptions of Nonbonded Interactions. Journal of Chemical Information and Modeling, 49(4), 944-955. DOI: 10.1021/ci900009f
This is a brief report and some links from the second day of Network Applications and Tools in Biology (NETTAB 2009) in Catania, Sicily. There were two keynotes on the RNA WikiProject  by Alex Bateman and myExperiment  (by me) as as well as presentations by (I think but I wasn’t concentrating enough) Dietlind [...]... Read more »
Daub, J., Gardner, P., Tate, J., Ramskold, D., Manske, M., Scott, W., Weinberg, Z., Griffiths-Jones, S., & Bateman, A. (2008) The RNA WikiProject: Community annotation of RNA families. RNA, 14(12), 2462-2464. DOI: 10.1261/rna.1200508
Gardner, P., Daub, J., Tate, J., Nawrocki, E., Kolbe, D., Lindgreen, S., Wilkinson, A., Finn, R., Griffiths-Jones, S., Eddy, S.... (2009) Rfam: updates to the RNA families database. Nucleic Acids Research, 37(Database). DOI: 10.1093/nar/gkn766
Reyes-Palomares, A., Montanez, R., Real-Chicharro, A., Chniber, O., Kerzazi, A., Navas-Delgado, I., Medina, M., Aldana-Montes, J., & Sanchez-Jimenez, F. (2009) Systems biology metabolic modeling assistant: an ontology-based tool for the integration of metabolic data in kinetic modeling. Bioinformatics, 25(6), 834-835. DOI: 10.1093/bioinformatics/btp061
How many ways are there for defining vulnerability and criticality, really? Traditionally, risk matrixes have a likelihood/impact approach, but not always. Yesterday, I was examining a criticality/vulnerability matrix. Today, I will take a closer look at a criticality/preparedness matrix with a third susceptibility dimension added to it, as presented in the New Zealand research project [...]... Read more »
Erica Seville, David Brunsdon, Andre Dantas, Jason Le Masurier, Suzanne Wilkinson, & John Vargo. (2008) Organisational resilience: Researching the reality of New Zealand organisations. Journal of Business Continuity , 2(3), 258-266. DOI: henrystewart.metapress.com/index/Q5W8L24Q93842U01.pdf
New evidence that the closest living relative of humans is the orangutan, and not the chimpanzee.... Read more »
John R. Grehan1 and Jeffrey H. Schwartz. (2009) Evolution of the second orangutan: phylogeny and biogeography of hominid origins. Journal of Biogeography. DOI: http://www.blackwellpublishing.com/pdf/jbi_2141.pdf
What are the causes of homosexual behavior in animals? Contrary to what most people probably think, homosexual behavior is not just common in animals, it is catholic.
A new paper in TREE has gotten a lot of press (most papers on sex do, I suspect): Same-sex sexual behavior and evolution, by Bailey and Zuk at UC Riverside.... Read more »
Nathan W. Bailey, Marlene Zuk. (2009) Same-sex sexual behavior and evolution. Trends in Ecology . DOI: http://www.sciencedirect.com/science/article/B6VJ1-4WJ8FG7-1/2/a146e8248e9ca604894abfd9f0c3aabd
To call Jerusalem a disputed location would be an under-statement. The Temple Mount in that city might be the most hotly contested piece of real estate on the planet, sacred as it is to the 3 major western religions: Judaism, Christianity, and Islam. Archaeologists believe that there has been a city on the site of Jerusalem since about 2600 BCE, meaning that for nearly 5000 years, various groups of people have fought over the landscape: Judeans, Israelites, Assyrians, Babylonians, Persians, Gre........ Read more »
Greenberg, R. (2009) "Towards an Inclusive Archaeology in Jerusalem: The Case of Silwan/The City of David.". Public Archaeology, 8(1), 35-50. DOI: 10.1179/175355309X402745
[Originally posted in April 2007]
One "trick" dieters often use is to put their food on a smaller plate. The idea is to fool yourself into thinking you're eating more food than you really are. But doesn't our stomach tell us how full we are?
Actually, it doesn't. Brian Wansink has devoted his career to studying how perception of food intake relates to actual eating behavior. Together with James Painter and Jill North, he's come up with a dramatic demonstration of how wrong our stomachs can be......... Read more »
Wansink, B., Painter, J.E., & North, J. (2005) Bottomless Bowls: Why Visual Cues of Portion Size May Influence Intake. Obesity Research, 13(1), 93-100.
News from my Newcastle University published today reveals that cooking carrots whole and then chopping them before serving is better for your health than slicing and dicing before you boil.
Apparently, less of the “anticancer” compound falcarinol leaches out of the carrots and into the cooking water if carrots are boiled whole. Of course, the truly [...]... Read more »
Christensen, L., Vach, W., Ritskes-Hoitinga, J., & Brandt, K. (2005) Inhibitory Effects of Feeding with Carrots or (−)-Falcarinol on Development of Azoxymethane-Induced Preneoplastic Lesions in the Rat Colon. Journal of Agricultural and Food Chemistry, 53(5), 1823-1827. DOI: 10.1021/jf048519s
Geoengineering is the idea that humans can slow, stop or reverse the effects of climate change by altering the composition of Earth’s atmosphere and biosphere. While controversial, these methods, including reducing sun exposure by injecting aerosols into the atmosphere or using giant mirrors to reflect the sun’s rays, were identified as a high-priority area for [...]... Read more »
Matthews, H. D., L. Cao, & K. Caldeira. (2009) Sensitivity of ocean acidification to geoengineered climate stabilization. Geophysical Research Letters. DOI: http://www.agu.org/pubs/crossref/2009/2009GL037488.shtml
Photo by Marina KomolovaOne topic that never fails to generate a lively discussion is the relationship between obesity and personal responsibility. For example, in response to a post on psychological exams for bariatric surgery patients, one anonymous reader commented that: I don't have a gym membership. I'm not even all that active. I live in a bad neighbourhood and i'm floating right around the Canadian poverty line. I'm not obese. When I see a little extra belly buil........ Read more »
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