Barriers to dispersal come in all shapes and sizes and not all are obvious. Baker conducted experiments with jumping spiders, Phidippus princeps (Salticidae) in which he manipulated corridors connecting patches of old growth fields (clover and alfalfa). Patches were either not connected (bare corridors), all connected, or partly connected by vegetated corridors (see schema [...]... Read more »
Baker, L. (2007) Effect of corridors on the movement behavior of the jumping spider Phidippus princeps (Araneae, Salticidae). Canadian Journal of Zoology, 85(7), 802-808. DOI: 10.1139/Z07-061
We just came across a fancy patient information form that was given to a patient after an assessment by a clinician. The form just blew our minds (but not in a good way) because it seemed to be the perfect clinical tool for generating ongoing pain and disability, and all by the simple process of [...]... Read more »
Beattie PF, Meyers SP, Stratford P, Millard RW, & Hollenberg GM. (2000) Associations between patient report of symptoms and anatomic impairment visible on lumbar magnetic resonance imaging. Spine, 25(7), 819-28. PMID: 10751293
Borenstein DG, O'Mara JW Jr, Boden SD, Lauerman WC, Jacobson A, Platenberg C, Schellinger D, & Wiesel SW. (2001) The value of magnetic resonance imaging of the lumbar spine to predict low-back pain in asymptomatic subjects : a seven-year follow-up study. The Journal of bone and joint surgery. American volume, 83-A(9), 1306-11. PMID: 11568190
Kalichman L, Li L, Kim DH, Guermazi A, Berkin V, O'Donnell CJ, Hoffmann U, Cole R, & Hunter DJ. (2008) Facet joint osteoarthritis and low back pain in the community-based population. Spine, 33(23), 2560-5. PMID: 18923337
Kalichman L, Kim DH, Li L, Guermazi A, Berkin V, & Hunter DJ. (2009) Spondylolysis and spondylolisthesis: prevalence and association with low back pain in the adult community-based population. Spine, 34(2), 199-205. PMID: 19139672
Mirtz TA, Morgan L, Wyatt LH, & Greene L. (2009) An epidemiological examination of the subluxation construct using Hill's criteria of causation. Chiropractic , 13. PMID: 19954544
Moseley GL. (2003) A pain neuromatrix approach to patients with chronic pain. Manual therapy, 8(3), 130-40. PMID: 12909433
Obesity is now increasingly recognised as the “natural” consequence of societal changes that have occurred over the past decades to foster an increasingly obesogenic environment.
Yet, rather than focus on the root causes of these societal drivers of obesity, governments apparently prefer to make obesity prevention a personal matter, with a strong emphasis on trying to [...]... Read more »
Alvaro C, Jackson LA, Kirk S, McHugh TL, Hughes J, Chircop A, & Lyons RF. (2010) Moving governmental policies beyond a focus on individual lifestyle: some insights from complexity and critical theories. Health promotion international. PMID: 20709791
I am constantly on the lookout for studies on how biochemical mechanisms shift with age, the significance of these changes and how nutrition and lifestyle interact with them to potentially affect health. Ageing itself is clearly an immensely complex process, and teasing … Continue reading →... Read more »
Einstein FH, Huffman DM, Fishman S, Jerschow E, Heo HJ, Atzmon G, Schechter C, Barzilai N, & Muzumdar RH. (2010) Aging per se increases the susceptibility to free fatty acid-induced insulin resistance. The journals of gerontology. Series A, Biological sciences and medical sciences, 65(8), 800-8. PMID: 20504893
The Derringer pistol:
Pros: Easy concealment. Stylish.
Con: You’ve only got one shot.
Argiope bruennichi of the male variety are rather like Derringer pistols. Because, you see, their sex organs tend to break during mating.
Yes. Break off.
You almost can’t help but wonder if being eaten by the female – which is the fate for a large percentage of them – isn’t almost a relief to the poor boys at that point.
When you only one shot at genetic glory, you would expect to aim at the ta........ Read more »
Schulte, K., Uhl, G., & Schneider, J. (2010) Mate choice in males with one-shot genitalia: limited importance of female fecundity. Animal Behaviour. DOI: 10.1016/j.anbehav.2010.07.005
Nearly everyone has heard of developmental dyslexia – a learning disorder characterized by poor reading skills despite otherwise sufficient schooling – but have you heard of developmental dyscalculia? Many people have not. Here is part 4 in a week-long series on this lesser-known learning disorder. Case-studies of patients with various brain lesions have demonstrated the [...]... Read more »
Isaacs EB, Edmonds CJ, Lucas A, & Gadian DG. (2001) Calculation difficulties in children of very low birthweight: a neural correlate. Brain : a journal of neurology, 124(Pt 9), 1701-7. PMID: 11522573
Molko N, Cachia A, Rivière D, Mangin JF, Bruandet M, Le Bihan D, Cohen L, & Dehaene S. (2003) Functional and structural alterations of the intraparietal sulcus in a developmental dyscalculia of genetic origin. Neuron, 40(4), 847-58. PMID: 14622587
Dehaene, S, Piazza, M, Pinel, P, & Cohen, L. (2003) Three Parietal Circuits for Number Processing. Cognitive Neuropsychology, 487-506. info:/
The March issue of International Microbiology included a very nice article by Roberto Kolter, professor of Microbiology and Molecular Genetics at Harvard Medical School. The title is Biofilms in lab and nature: a molecular geneticist’s voyage to microbial ecology (freely available as PDF).In the article, the author gives an entertaining account of the path that lead him to the study of biofilms -- that is, aggregations of microbes growing on solid substrates. He also highlights some of his rec........ Read more »
Roberto Kolter. (2010) Biofilms in lab and nature: a molecular geneticist’s voyage to microbial ecology. Int. Microbiol., 1-7. info:/10.2436/20.1501.01.105
Rosy Apple Aphid (Whalon lab, MSU) Normally I don’t talk about research that’s well covered elsewhere, but I like this one so much (and it links back to so many of my earlier posts; check the footnotes for those links) that I’ll make an exception here. I’d seen bits and pieces of this story, but [...]... Read more »
Oliver KM, Degnan PH, Hunter MS, & Moran NA. (2009) Bacteriophages encode factors required for protection in a symbiotic mutualism. Science (New York, N.Y.), 325(5943), 992-4. PMID: 19696350
Degnan PH, Yu Y, Sisneros N, Wing RA, & Moran NA. (2009) Hamiltonella defensa, genome evolution of protective bacterial endosymbiont from pathogenic ancestors. Proceedings of the National Academy of Sciences of the United States of America, 106(22), 9063-8. PMID: 19451630
Degnan PH, & Moran NA. (2008) Evolutionary genetics of a defensive facultative symbiont of insects: exchange of toxin-encoding bacteriophage. Molecular ecology, 17(3), 916-29. PMID: 18179430
Degnan PH, & Moran NA. (2008) Diverse phage-encoded toxins in a protective insect endosymbiont. Applied and environmental microbiology, 74(21), 6782-91. PMID: 18791000
Continuing my series on the Evolution of Colour terms, this post reviews evidence for perceptual constraints on colour terms. For the full dissertation and for references, go here.
The perceptual space that results from the processing of opponent colours is non-uniform (see Figure below), meaning that there are optimal ways to describe it (Jameson & D’Andrade, . . . → Read More: Evolution of Colour Terms: 3 Perceptual Constraints... Read more »
Jameson, K., & D'Andrade, R.G. (1997) It's not really Red, Green, Yellow, Blue: An Inquiry into cognitive color space. Color Categories in Thought and Language. DOI: 10.1017/CBO9780511519819.014
Regier, T., Kay, P., & Khetarpal, N. (2007) Color naming reflects optimal partitions of color space. Proceedings of the National Academy of Sciences, 104(4), 1436-1441. DOI: 10.1073/pnas.0610341104
Liljencrants, J., Lindblom, B., & Lindblom, B. (1972) Numerical Simulation of Vowel Quality Systems: The Role of Perceptual Contrast. Language, 48(4), 839. DOI: 10.2307/411991
Buchsbaum, G. (2002) Color categories revealed by non-negative matrix factorization of Munsell color spectra. Vision Research, 42(5), 559-563. DOI: 10.1016/S0042-6989(01)00303-0
While everybody was busy talking about unexpectedly old cutmarks and other Pleistocene goings-on last week, the paper by Strasser et al. (2010) describing the discovery of quartz handaxe assemblages on Crete quietly came out in Hesperia. This is a topic that was discussed at length on this blog, in several posts that generated a large amount of comments a few months back. The sticking point of ... Read more »
Strasser, T., Panagopoulou, E., Runnels, C., Murray, P., Thompson, N., Karkanas, P., McCoy, F., & Wegmann, K. (2010) Stone Age Seafaring in the Mediterranean: Evidence from the Plakias Region for Lower Palaeolithic and Mesolithic Habitation of Crete. Hesperia, 79(2), 145-190. DOI: 10.2972/hesp.79.2.145
You can think of a lot such as technical procedures or washing your hands. For residents it’s obvious. Mostly learning the technical procedure of an operation. During long operations I used to count the number of stitches. Once during a vascular operation the chief surgeon out of the blue asked what vessel it was they’re [...]
Related posts:Bedside teaching, Computer Based Learning and Wiki in Medical Education
Personalized Medical Education
Empathy for the Mentally Ill in Medical........ Read more »
Irani, J., Greenberg, J., Blanco, M., Greenberg, C., Ashley, S., Lipsitz, S., Hafler, J., & Breen, E. (2010) Educational value of the operating room experience during a core surgical clerkship. The American Journal of Surgery, 200(1), 167-172. DOI: 10.1016/j.amjsurg.2009.06.023
One of the fundamental concepts of quantum mechanics is that objects can be described as waves, whether they are electrons, atoms, light, anything really, even your cat (or that of Erwin Schrödinger). And of course, if the equations that describe their wavefunctions are identical, objects will behave in the same way. Even if they are fundamentally different physical entities.
Two papers published this week highlight just how far this analogy can go. In one study a gas of ultracold atoms beha........ Read more »
Sherson, J., Weitenberg, C., Endres, M., Cheneau, M., Bloch, I., & Kuhr, S. (2010) Single-atom-resolved fluorescence imaging of an atomic Mott insulator. Nature. DOI: 10.1038/nature09378
Manning, A., Hodgman, S., Dall, R., Johnsson, M., & Truscott, A. (2010) The Hanbury Brown-Twiss effect in a pulsed atom laser. Optics Express, 18(18), 18712. DOI: 10.1364/OE.18.018712
A few years ago, a cousin of mine told me the story of the time she was at a public swimming pool (in Utah, I believe) when her infant son demanded to be fed. She did what came naturally: she began to breastfeed her son. This act didn't go over very well with at least one of the pool's patrons, who came over to my cousin and sneered "That's disgusting! I have young children and they don't need to see that!" My cousin mused on how curious it was that this lady wasn't bothered by her children ........ Read more »
Hsu, M., Hsu, Y., & Wu, W. (2002) Consumption of flea faeces and eggs by larvae of the cat flea, Ctenocephalides felis. Medical and Veterinary Entomology, 16(4), 445-447. DOI: 10.1046/j.1365-2915.2002.00388.x
Laurent Cognet (Universite de Bordeaux, France) and coworkers have used PAINT microscopy to track tens of thousands of protein binding events in cell membranes within a few minutes, extremely useful for unraveling secrets of cell membrane physiology. This news feature was written on August 18, 2010.... Read more »
Giannone, G., Hosy, E., Levet, F., Constals, A., Schulze, K., Sobolevsky, A. I., Rosconi, M. P., Gouaux, E., Tampé, R., & Choquet, D. (2010) Dynamic Superresolution Imaging of Endogenous Proteins on Living Cells at Ultra-High Density. Biophysical Journal, 99(4), 1303-1310. DOI: 10.1016/j.bpj.2010.06.005
Some months ago, Jonathan Green and his colleagues simultaneously published (in the Lancet) and presented (at IMFAR 2010) their multi-site RCT of an early autism intervention. In conducting and reporting the Pre-school Autism Communication Trial, they have made autism research history. They have done so simply by applying to autistics scientific standards that are well-established in non-autism non-ABA areas. The upshot is an autism early intervention trial whose results are worth serious consid........ Read more »
Green, J., Charman, T., McConachie, H., Aldred, C., Slonims, V., Howlin, P., Le Couteur, A., Leadbitter, K., Hudry, K., & Byford, S. (2010) Parent-mediated communication-focused treatment in children with autism (PACT): a randomised controlled trial. The Lancet, 375(9732), 2152-2160. DOI: 10.1016/S0140-6736(10)60587-9
Spence, S., & Thurm, A. (2010) Testing autism interventions: trials and tribulations. The Lancet, 375(9732), 2124-2125. DOI: 10.1016/S0140-6736(10)60757-X
Emerging infectious diseases do not only affect humans. Wildlife is threatened as well, and an alarming report from Britain documents an avian tragedy of great proportions. Read the rest of this post... | Read the comments on this post...... Read more »
Robinson, Robert, Lawson, Becki, Toms, Mike, Peck, Kirsi, Kirckwood,James, Chantrye, Julian, Clatworthy, Innes, Evans, Andy, Hughes, Laura, Hutchinson, Oliver.... (2010) Emerging Infectious Disease Leads to Rapid Population Declines of Common British Birds . PLoS ONE, 5(8). info:/
Diet medications may damage your liver, low-carbohydrate diets can cause kidney failure, and gastric bypass carries with it all the risks and complications of any body-altering surgery. However, recent research has suggested a slightly less risky fat-fighting alternative: seaweed.... Read more »
PAXMAN, J., RICHARDSON, J., DETTMAR, P., & CORFE, B. (2008) Alginate reduces the increased uptake of cholesterol and glucose in overweight male subjects: a pilot study. Nutrition Research, 28(8), 501-505. DOI: 10.1016/j.nutres.2008.05.008
Brownlee, I., Allen, A., Pearson, J., Dettmar, P., Havler, M., Atherton, M., & Onsøyen, E. (2005) Alginate as a Source of Dietary Fiber. Critical Reviews in Food Science and Nutrition, 45(6), 497-510. DOI: 10.1080/10408390500285673
In the guts of each of us there are trillions of microbes. They provide us with "enhanced metabolic capabilities, protection against pathogens, education of the immune system, and modulation of gastrointestinal development" (De Filippo et al. 2010). The diversity of these organisms can play a role in the future development of disease. But, what makes our guts so diverse? As De Filippo et al. (2010) report, one main factor appears to be diet.... Read more »
De Filippo C, Cavalieri D, Di Paola M, Ramazzotti M, Poullet JB, Massart S, Collini S, Pieraccini G, & Lionetti P. (2010) Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proceedings of the National Academy of Sciences of the United States of America. PMID: 20679230
Arthur Michalek (Roswell Park Cancer Institute, United States) and coworkers show that scientific misconduct costs a tremendous amount of money, and is definitely not a "victimless crime." This news feature was written on August 18, 2010.... Read more »
Michalek, A. M., Hutson, A. D., Wicher, C. P., & Trump, D. L. (2010) The Costs and Underappreciated Consequences of Research Misconduct: A Case Study. PLoS Medicine, 7(8). DOI: 10.1371/journal.pmed.1000318
sourceThe recreational drug 4-methylmethcathinone (4-MMC; aka mephedrone, MMCAT) was legal in the UK up until mid April of this year. I had previously covered the only work in a behaving animal model that I could find, a paper using drug-discrimination techniques to evaluate the discriminative stimulus (aka, subjective) properties of several cathinone derivative compounds (but [...]... Read more »
Torrance H, & Cooper G. (2010) The detection of mephedrone (4-methylmethcathinone) in 4 fatalities in Scotland. Forensic science international. PMID: 20685050
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