Post List

  • October 20, 2014
  • 10:56 AM
  • 133 views

Persistent Insomnia and Alcoholism

by William Yates, M.D. in Brain Posts

Sleep problems complicate the treatment and recovery in alcoholism. Heavy alcohol consumption modifies the nature of sleep architecture.A high blood alcohol concentration at bedtime may promote sleep early in the sleep cycle.However, as alcohol levels decline, sleep is often interrupted with limiting rapid eye movement (REM) sleep duration.Shortened total sleep time with alcohol can produce a lack of feeling well rested on awakening.For those with alcoholism or alcohol dependence, successfu........ Read more »

Brower KJ, Krentzman A, & Robinson EA. (2011) Persistent insomnia, abstinence, and moderate drinking in alcohol-dependent individuals. The American journal on addictions / American Academy of Psychiatrists in Alcoholism and Addictions, 20(5), 435-40. PMID: 21838842  

  • October 20, 2014
  • 07:02 AM
  • 147 views

Morality in everyday life for the religious and the nonreligious

by Rita Handrich in The Jury Room

The researchers recruited a sample of 1,252 adults ranging in age from 18 to 68 years of age who reside in the US and Canada. Each participant completed measures of religiosity and political ideation prior to participation in the actual study. All participants had smartphones and were randomly signaled on their phone for 3 days […]

Related posts:
Should I choose the creative juror, the introvert/extravert, or the religious juror?
“Everyday liars” and “Prolific liarsR........ Read more »

Hofmann W, Wisneski DC, Brandt MJ, & Skitka LJ. (2014) Morality in everyday life. Science (New York, N.Y.), 345(6202), 1340-3. PMID: 25214626  

  • October 20, 2014
  • 05:38 AM
  • 126 views

Removing Disease from the Genome

by Gunnar de Winter in United Academics

Using agenetic cut-and-paste system, scientists have removed and replaced the gene causing muscular dystrophy in mice.... Read more »

Long C, McAnally JR, Shelton JM, Mireault AA, Bassel-Duby R, & Olson EN. (2014) Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA. Science (New York, N.Y.), 345(6201), 1184-8. PMID: 25123483  

  • October 20, 2014
  • 04:46 AM
  • 93 views

Decades of lie detection research has been unrealistic

by BPS Research Digest in BPS Research Digest

According to decades of psychology research, most people, including law enforcement professionals, are useless at detecting lies. But in a new paper, a team led by Tim Levine argues that nearly all previous research has been unrealistic. The field has been dominated by studies that place the "lie detector" in a passive role, tasked with spotting "tells" leaked by the liar. But this just isn't how deception detection works in real life, say Levine and his team. Rather, the interrogator interacts ........ Read more »

  • October 20, 2014
  • 04:36 AM
  • 125 views

Reasons for visiting ER by those with autism

by Paul Whiteley in Questioning Answers

ER - Emergency Room - or as we call it here in Blighty Accident & Emergency (A & E), is never a particularly desirable place to visit given the emphasis on illness or injury of yourself or loved one. That being said, staff there do a sterling job sometimes under very stressful circumstances, responding to all-manner of complaints, some of which are life-threatening.The paper by Dorothea Iannuzzi and colleagues [1] sought to identify some of the medical reasons why ER visit........ Read more »

Iannuzzi DA, Cheng ER, Broder-Fingert S, & Bauman ML. (2014) Brief Report: Emergency Department Utilization by Individuals with Autism. Journal of autism and developmental disorders. PMID: 25261249  

  • October 20, 2014
  • 12:05 AM
  • 119 views

Novel NSAID has Differential Tissue Effects in the Treatment of Chronic Rotator Cuff Repairs

by Sarah Ilkhanipour Rooney in Sports Medicine Research (SMR): In the Lab & In the Field

Licofelone, a non-steroidal anti-inflammatory treatment, has tissue-specific effects. In a rotator cuff repair rat model, this drug reduces functional muscle regeneration but improves tendon healing.... Read more »

  • October 19, 2014
  • 07:11 PM
  • 130 views

Running Shoes Can Control Motion

by Craig Payne in Running Research Junkie

Running Shoes Can Control Motion... Read more »

  • October 19, 2014
  • 06:39 PM
  • 143 views

Pain is not a "Thing"

by Bronwyn Thompson in Healthskills: Skills for Healthy Living

ResearchBlogging.org
I’m reading some fascinating books at the moment. I’m such a pain geek I take pain books away with me on holiday! Anyway, the two books to hit me between the eyeballs recently are The Pain Chronicles by Melanie Thernstrom (published 2010), and The Story of Pain by Joanna Bourke (published 2014). What makes both of these books fascinating is that these both look at the history of pain and pain management, and explore the “what it is like” to be in pai........ Read more »

Ashton-James, C., Richardson, D., Williams, A., Bianchi-Berthouze, N., & Dekker, P. (2014) Impact of pain behaviors on evaluations of warmth and competence. PAIN®. DOI: 10.1016/j.pain.2014.09.031  

  • October 19, 2014
  • 01:43 PM
  • 144 views

DNA Nanotech: The First Large DNA Crystals

by Gabriel in Lunatic Laboratories

DNA is the stuff of life as we know it, but it is the potential as a programmable material platform that could spawn entire new and revolutionary nanodevices in computer science, microscopy, biology, and more. Researchers have been working to master the ability to coax DNA molecules to self assemble into the precise shapes and sizes needed in order to fully realize these nanotechnology dreams. A dream that been going on for 20 years now and was just realized.... Read more »

Ke, Y., Ong, L., Sun, W., Song, J., Dong, M., Shih, W., & Yin, P. (2014) DNA brick crystals with prescribed depths. Nature Chemistry. DOI: 10.1038/nchem.2083  

  • October 19, 2014
  • 11:00 AM
  • 132 views

Ten years into the making, the HIV-1 mosaic vaccine finally goes into human trial

by EE Giorgi in CHIMERAS

© Bette Korber et al. I hope you will all forgive me if this week I'm gushing over my amazing mentor Bette Korber, as last week she shared some awesome news on Facebook:"A landmark in my life happened yesterday, a major step in a long story. A decade ago I had an idea for making an HIV vaccine that had the potential to work globally. After a struggle (in my first 2 failed proposals, reviewers declared what I proposed was impossible), I got an internal grant from Los Alamos to develop the idea (........ Read more »

Fischer W, Perkins S, Theiler J, Bhattacharya T, Yusim K, Funkhouser R, Kuiken C, Haynes B, Letvin NL, Walker BD.... (2007) Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants. Nature medicine, 13(1), 100-6. PMID: 17187074  

Nkolola JP, Bricault CA, Cheung A, Shields J, Perry J, Kovacs JM, Giorgi E, van Winsen M, Apetri A, Brinkman-van der Linden EC.... (2014) Characterization and immunogenicity of a novel mosaic M HIV-1 gp140 trimer. Journal of virology, 88(17), 9538-52. PMID: 24965452  

Barouch DH, Stephenson KE, Borducchi EN, Smith K, Stanley K, McNally AG, Liu J, Abbink P, Maxfield LF, Seaman MS.... (2013) Protective efficacy of a global HIV-1 mosaic vaccine against heterologous SHIV challenges in rhesus monkeys. Cell, 155(3), 531-9. PMID: 24243013  

Barouch DH, O'Brien KL, Simmons NL, King SL, Abbink P, Maxfield LF, Sun YH, La Porte A, Riggs AM, Lynch DM.... (2010) Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeys. Nature medicine, 16(3), 319-23. PMID: 20173752  

  • October 19, 2014
  • 07:24 AM
  • 52 views

Power Makes People Deliberate Less Over Emails

by Neuroskeptic in Neuroskeptic_Discover

When it comes to emails, power makes people spend less time thinking and more time typing. So say German cyber-psychologists Annika Scholl and Kai Sassenberg in a new paper just published: Experienced Social Power Reduces Deliberation During E-Mail Communication In their study, they recruited 49 undergraduate students. Each participant was first randomly assigned to play […]The post Power Makes People Deliberate Less Over Emails appeared first on Neuroskeptic.... Read more »

  • October 18, 2014
  • 02:55 PM
  • 140 views

New Genetic Test to help Solve Rare Disease Diagnosis

by Gabriel in Lunatic Laboratories

My sister suffers from a rare disease which causes small fiber polyneuropathy, or the killing of nerves in her hands and feet. As it progresses she has trouble standing or using her hands. If that was the worst of it, then it might be liveable given the time between severe attacks is years or more. Unfortunately, it also causes intense and mostly constant pain and burning sensations, pain so bad that conventional narcotic painkillers have trouble controlling it. After some time working with the ........ Read more »

Lee, H., Deignan, J., Dorrani, N., Strom, S., Kantarci, S., Quintero-Rivera, F., Das, K., Toy, T., Harry, B., Yourshaw, M.... (2014) Clinical Exome Sequencing for Genetic Identification of Rare Mendelian Disorders. JAMA. DOI: 10.1001/jama.2014.14604  

  • October 18, 2014
  • 09:45 AM
  • 119 views

Immunoglobulin E: not just a bystander in lupus?

by Aurelie in The Immuno Blog

IgE antibodies are mostly known for their pathophysiological role in allergic reactions and in certain immune deficiencies referred to as hyper-IgE syndromes. In a study published in The Journal of Experimental Medicine in September, Dema et al. find that IgE … Continue reading →... Read more »

Dema B, Charles N, Pellefigues C, Ricks TK, Suzuki R, Jiang C, Scheffel J, Hasni S, Hoffman V, Jablonski M.... (2014) Immunoglobulin E plays an immunoregulatory role in lupus. The Journal of experimental medicine. PMID: 25267791  

  • October 18, 2014
  • 09:34 AM
  • 175 views

Merit’s Liquidity

by nooffensebut in The Unsilenced Science

The latest SAT and ACT data suggest that America’s cognitive elite have been enjoying new geographic mobility, but difficult economic times push them out of the elite strata, contrary to a prediction of The Bell Curve by Richard Herrnstein and Charles Murray.... Read more »

nooffensebut. (2014) Parents’ Income is a Poor Predictor of SAT Score. Open Differential Psychology, 1-19. info:other/

  • October 18, 2014
  • 05:30 AM
  • 123 views

More epigenetics, EN-2 and autism... the plot thickens

by Paul Whiteley in Questioning Answers

I don't mind admitting that I was to some extent 'winging it' with my previous post on epigenetics and Engrailed-2 (EN-2) as a consequence of the findings reported by Jill James and colleagues [1] with autism in mind. Although an avid follower of the science of epigenetics when (cautiously) applied to autism, I am by no means any authority on the subject matter particularly when it comes to the nitty-gritty details. You can probably therefore expect similar things in my latest discussi........ Read more »

  • October 18, 2014
  • 01:42 AM
  • 101 views

Full-term developmet of quail chick by ICSI

by Mizushima S in the Node

The eggs of domestic birds have been used in the study of developmental biology, leading to the extensive accumulation of knowledge on embryonic development. However, the early events involved in bird development, particularly the mechanism underlying fertilization, have not been elucidated in as much detail as those of other species of animals. The ooplasm in […]... Read more »

Mizushima, S., Hiyama, G., Shiba, K., Inaba, K., Dohra, H., Ono, T., Shimada, K., & Sasanami, T. (2014) The birth of quail chicks after intracytoplasmic sperm injection. Development, 141(19), 3799-3806. DOI: 10.1242/dev.111765  

  • October 17, 2014
  • 10:29 PM
  • 130 views

Translational Findings: Fruit fly contributions to research in circadian rhythms

by Bethany Christmann in Fly on the Wall

What are circadian rhythms, and why are they important to humans? Over the past century, technological innovations have changed human society dramatically, undeniably for the better. But the advent of jet travel, round-the-clock manufacturing, and internet communication has also had a disruptive effect on our bodies’ circadian rhythms. The word “circadian” comes from the latin […]... Read more »

  • October 17, 2014
  • 04:02 PM
  • 176 views

A look at Air Pollution and Your Body

by Gabriel in Lunatic Laboratories

We have all probably seen stories from China on the horrid air pollution there. Accompanying those reports of course are the statistics for air pollution that deaths have caused. For the record, the World Health Organization estimated that ambient air pollution caused 3.7 million premature deaths (worldwide) in 2012 alone – yet what exactly happens to your body when it encounters pollutants?... Read more »

  • October 17, 2014
  • 11:40 AM
  • 128 views

October 17, 2014

by Erin Campbell in HighMag Blog

For years the prettiest cells to image were flat cells in a dish. Thanks to the tireless work of many, beautiful high-resolution images can now come from tissue in a living organism. Today’s image is from a paper showing improved techniques for imaging fine cellular processes within large volumes, from the lab of recent Nobel prize winner, Eric Betzig. A material’s refractive index refers to how light travels through it; the simplest example being how light bends when passed through wat........ Read more »

Wang, K., Milkie, D., Saxena, A., Engerer, P., Misgeld, T., Bronner, M., Mumm, J., & Betzig, E. (2014) Rapid adaptive optical recovery of optimal resolution over large volumes. Nature Methods, 11(6), 625-628. DOI: 10.1038/nmeth.2925  

  • October 17, 2014
  • 08:55 AM
  • 165 views

People Are More Swayed by Things That Look Sciencey

by Elizabeth Preston in Inkfish

Anyone who’s paged through a women’s magazine will recognize this strategy: to make a product seem better, surround it with a scientific glow. “Clinical trials show lashes grow up to 400% fuller!” “27% reduction of dark spots in 10 weeks!” “Ceramides!” Does this actually help convince people to hand over their cash? A study using […]The post People Are More Swayed by Things That Look Sciencey appeared first on Inkfish.... Read more »

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