Post List

  • June 14, 2016
  • 11:15 AM

Our Bodies Were Not Built To Last

by Jason Organ in The 'Scope

Evolution reveals why the human body deteriorates with age... Read more »

  • June 14, 2016
  • 08:47 AM

MaMaLoc: How To Change Cancer Surgeries With Magnets

by Rita dos Santos Silva in United Academics

A small magnetic device might transform breast cancer surgeries... Read more »

Anderson, R., Kimmick, G., McCoy, T., Hopkins, J., Levine, E., Miller, G., Ribisl, P., & Mihalko, S. (2011) A randomized trial of exercise on well-being and function following breast cancer surgery: the RESTORE trial. Journal of Cancer Survivorship, 6(2), 172-181. DOI: 10.1007/s11764-011-0208-4  

Lovrics, P., Cornacchi, S., Vora, R., Goldsmith, C., & Kahnamoui, K. (2011) Systematic review of radioguided surgery for non-palpable breast cancer. European Journal of Surgical Oncology (EJSO), 37(5), 388-397. DOI: 10.1016/j.ejso.2011.01.018  

  • June 14, 2016
  • 04:50 AM

Fingerprint matching is biased by the assessor's prejudices

by BPS Research Digest in BPS Research Digest

When we think of crime scene forensics, it’s easy to view it as the objective end of criminal investigation. Witnesses waffle, suspects slide around from the truth, and jurors can be misled by emotive evidence. but the physical evidence simply is what it is. Yet forensic work requires human judgment, and opens the door for human error: for example, a tendency to evaluate evidence differently depending on background information. Now a new study in Law and Human Behaviour suggests that investiga........ Read more »

  • June 14, 2016
  • 03:01 AM

Xenodiagnosis to detect Borrelia burgdorferi in humans

by Microbe Fan in Spirochetes Unwound

We've seen that live Borrelia burgdorferi persists (in unculturable form) when infected mice are treated with antibiotics.  What we don't know is whether they persist in humans with post-treatment Lyme disease syndrome (PTLDS), which refers to the lingering long-term symptoms experienced by a minority of Lyme disease patients who have been treated with the standard course of antibiotics.In theory, one could simply determine whether B. burgdorferi can be detected in bits of tissue or blood e........ Read more »

Marques A, Telford SR 3rd, Turk SP, Chung E, Williams C, Dardick K, Krause PJ, Brandeburg C, Crowder CD, Carolan HE.... (2014) Xenodiagnosis to detect Borrelia burgdorferi infection: a first-in-human study. Clinical Infectious Diseases, 58(7), 937-45. PMID: 24523212  

Telford SR 3rd, Hu LT, & Marques A. (2014) Is there a place for xenodiagnosis in the clinic?. Expert Review of Anti-infective Therapy, 12(11), 1307-10. PMID: 25301228  

  • June 14, 2016
  • 02:42 AM

On fatty acid metabolism and autism and ADHD (again)

by Paul Whiteley in Questioning Answers

"Children with ADHD [attention-deficit hyperactivity disorder] and ASD [autism spectrum disorder] had low levels of EPA [eicosapentaenoic acid], DHA [docosahexaenoic acid] and AA [arachidonic acid] and high ratio of n-6/n-3 PUFAs [polyunsaturated fatty acid] and these correlated significantly with symptoms. Future research should further investigate abnormal fatty acid metabolism in these disorders."So said the research publication by Natalie Par........ Read more »

  • June 13, 2016
  • 08:30 PM

This Month in Blastocystis Research (MAY 2016)

by Christen Rune Stensvold in Blastocystis Parasite Blog

The May entry of "This Month in Blastocystis Research" focusses especially on the increasing interest in Blastocystis in a gut microbiota context. ... Read more »

Andersen LO, Bonde I, Nielsen HB, & Stensvold CR. (2015) A retrospective metagenomics approach to studying Blastocystis. FEMS microbiology ecology, 91(7). PMID: 26130823  

Stensvold CR, & Clark CG. (2016) Current status of Blastocystis: A personal view. Parasitology international. PMID: 27247124  

O'Brien Andersen L, Karim AB, Roager HM, Vigsnæs LK, Krogfelt KA, Licht TR, & Stensvold CR. (2016) Associations between common intestinal parasites and bacteria in humans as revealed by qPCR. European journal of clinical microbiology . PMID: 27230509  

Ramírez JD, Sánchez A, Hernández C, Flórez C, Bernal MC, Giraldo JC, Reyes P, López MC, García L, Cooper PJ.... (2016) Geographic distribution of human Blastocystis subtypes in South America. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 32-5. PMID: 27034056  

  • June 13, 2016
  • 01:43 PM

Experimental antibiotic treats deadly MRSA infection

by Dr. Jekyll in Lunatic Laboratories

The antibiotic arms race is on, while we are rushing to find new antibiotics, bacteria are working on finding ways around them. With that in mind, a new experimental antibiotic developed by a team of scientists successfully treats the deadly MRSA infection and restores the efficacy of a commonly prescribed antibiotic that has become ineffective against MRSA.

... Read more »

  • June 13, 2016
  • 10:51 AM

The best of both worlds

by SciELO in SciELO in Perspective

Quality is an ill-defined concept with regard to scholarly literature. Some aspects of quality can be assessed reasonably objectively, and immediately, such as the quality of presentation. But some cannot be readily determined, and need time and ‘digestion’ by the scholarly community, such as the scientific quality of an article. And then there is the quality of a journal’s service to authors, of particular importance for open access publishing that is supported by Article Processing Charg........ Read more »

  • June 13, 2016
  • 07:24 AM

Collateral Damage: Anti-cancer therapy and Autoimmune disease: Part I

by AG McCluskey in Zongo's Cancer Diaries

This post describes what Autoimmune diseases are. Part II will describe the potential of anti-cancer therapies as treatments for Autoimmune disease.... Read more »

Bell, E., & Bird, L. (2005) Autoimmunity. Nature, 435(7042), 583-583. DOI: 10.1038/435583a  

AG McCluskey. (2016) Collateral Damage. Zongo's Cancer Diaries. info:/

  • June 13, 2016
  • 07:02 AM

Maladaptive daydreaming: The next legal defense theory? 

by Doug Keene in The Jury Room

Remember Walter Mitty? He was a fictional character who escaped his dull day-to-day existence by constructing elaborate daydreams wherein he was the hero rather than a wallflower. Well, apparently Walter was not so unusual. There are people who spend as much as 60% of their time lost in daydreams. These are people who realize their […]

Related posts:
Can you trust the results of forensic evaluations on legal sanity?
Legal decisions that tick jurors off
Will your genetic defense for that........ Read more »

  • June 13, 2016
  • 02:34 AM

A gluten-free diet, gastrointestinal issues and autism

by Paul Whiteley in Questioning Answers

Given my own research interest in the use of specific dietary modifications as possible intervention tools for some aspects of some autism (see here) I was more than interested to read the results published by Faezeh Ghalichi and colleagues [1] following their randomised-controlled trial of a gluten-free diet (GFD) including some 80 children diagnosed with an autism spectrum disorder (ASD).As part of an area of much discussion, debate and also heated argument down the years, the author........ Read more »

  • June 12, 2016
  • 10:35 PM

Seeing Through the Skin

by Aurametrix team in Olfactics and Diagnostics

​Human skin emits light (albeit the glow is extremely weak) and a wide variety of small molecules that may be sometimes "sniffed" by dogs or even other humans. These chemicals tell a story about our health and wellness, things we eat and drink, touch and breathe. Mosquitoes use such emissions to assess our "attractiveness" from indicators such as Indoles (unpleasantly smelling but healthy "inner soil" biomarker) or carbon dioxide (amount of which correlates with the size of the person........ Read more »

Gao W, Emaminejad S, Nyein HY, Challa S, Chen K, Peck A, Fahad HM, Ota H, Shiraki H, Kiriya D.... (2016) Fully integrated wearable sensor arrays for multiplexed in situ perspiration analysis. Nature, 529(7587), 509-14. PMID: 26819044  

Yokota T, Zalar P, Kaltenbrunner M, Jinno H, Matsuhisa N, Kitanosako H, Tachibana Y, Yukita W, Koizumi M, & Someya T. (2016) Ultraflexible organic photonic skin. Science advances, 2(4). PMID: 27152354  

  • June 12, 2016
  • 02:23 PM

Researchers show copper is essential for burning fat

by Dr. Jekyll in Lunatic Laboratories

Is copper deficiency contributing to the obesity epidemic? Though small amounts of copper are essential to health - oysters, liver, beans and nuts are good sources - copper's role in metabolism has been unclear: Some studies found that it boosted fat burning, others that it depressed it.

... Read more »

Krishnamoorthy, L., Cotruvo, J., Chan, J., Kaluarachchi, H., Muchenditsi, A., Pendyala, V., Jia, S., Aron, A., Ackerman, C., Wal, M.... (2016) Copper regulates cyclic-AMP-dependent lipolysis. Nature Chemical Biology. DOI: 10.1038/nchembio.2098  

  • June 11, 2016
  • 10:02 PM

Natural Selection, Sexual Selection, and Chameleons

by Emily Makowski in Sextraordinary!

I discuss an upcoming article on how natural selection and sexual selection affect the courtship behavior of the common chameleon.... Read more »

Keren-Rotem, T., Levy, N., Wolf, L., Bouskila, A., & Geffen, E. (2016) Male preference for sexual signalling over crypsis is associated with alternative mating tactics. Animal Behaviour, 43-49. info:/

  • June 11, 2016
  • 05:29 AM

The Four-Dimensional Brain?

by Neuroskeptic in Neuroskeptic_Discover

"The brain is a three dimensional object." It would seem that this is one of the least controversial facts about the brain, something we can all agree on. But now, in a curious new paper, researchers Arturo Tozzi and James F. Peters suggest that the brain might have an extra dimension: Towards a fourth spatial dimension of brain activity

From topology, a strong concept comes into play in understanding brain functions, namely, the 4D space of a ‘‘hypersphere’s torus’’, undetectable by........ Read more »

Tozzi A, & Peters JF. (2016) Towards a fourth spatial dimension of brain activity. Cognitive neurodynamics, 10(3), 189-99. PMID: 27275375  

  • June 11, 2016
  • 03:51 AM

On biological markers and "subphenotypes" of autism

by Paul Whiteley in Questioning Answers

I don't want to keep you today. Just long enough to draw your attention to the paper by Jones and colleagues [1] regarding "ongoing efforts toward identification of early biological markers specific to subphenotypes of ASD [autism spectrum disorder]."The potential biomarkers in question this time around were the cytokines/chemokines - those various signalling molecules that seem to have more than a few connections to important processes like inflammation - and how their profile ("mid-gestat........ Read more »

  • June 10, 2016
  • 02:40 PM

New tool brings personalized medicine closer

by Dr. Jekyll in Lunatic Laboratories

Scientists have developed a powerful tool for exploring and determining the inherent biological differences between individuals, which overcomes a major hurdle for personalized medicine.

... Read more »

Williams, E., Wu, Y., Jha, P., Dubuis, S., Blattmann, P., Argmann, C., Houten, S., Amariuta, T., Wolski, W., Zamboni, N.... (2016) Systems proteomics of liver mitochondria function. Science, 352(6291). DOI: 10.1126/science.aad0189  

  • June 10, 2016
  • 02:14 PM

It can be a good thing for a therapist and client to disagree about the client's problems

by BPS Research Digest in BPS Research Digest

Rapport between a client and therapist is important for therapy to be successful, and part of that is agreeing about the aims of the exercise. You’d think this would include the therapist and client agreeing about the specific nature of the client’s psychological problems. In fact, a new study in Psychotherapy Research finds disagreement isn't harmful to therapy and can even be beneficial.Rolf Holmqvist and his colleagues recruited 846 therapy clients as they started a course of therapy at a........ Read more »

  • June 10, 2016
  • 01:51 PM

Yellow fever virus in Africa: current situation and importance

by thelonevirologist in Virology Tidbits

Yellow haemorraghic fever (YF) is caused by Yellow Fever Virus (YFV), a prototype Flavivirus and as such as related to Japanese Encephalitis Virus (JEV), Dengue Virus (DENV) and Zika Virus (ZIKV). Similar to DENV and ZIKV, YFV is transmitted by Aedes agypti both in Africa and South America and clinical manifestations range from asymptomatic infections to multi organ failure and subsequent death.Here the current outbreak in Angola is discussed. ... Read more »

Wasserman S, Tambyah PA, & Lim PL. (2016) Yellow fever cases in Asia: primed for an epidemic. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. PMID: 27156836  

Monath, T. (2001) Yellow fever: an update. The Lancet Infectious Diseases, 1(1), 11-20. DOI: 10.1016/S1473-3099(01)00016-0  

Carrington CV, & Auguste AJ. (2013) Evolutionary and ecological factors underlying the tempo and distribution of yellow fever virus activity. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 198-210. PMID: 22981999  

Cathey, J., & Marr, J. (2014) Yellow fever, Asia and the East African slave trade. Transactions of the Royal Society of Tropical Medicine and Hygiene, 108(8), 519-519. DOI: 10.1093/trstmh/tru081  

Monath TP. (1999) Facing up to re-emergence of urban yellow fever. Lancet (London, England), 353(9164), 1541. PMID: 10334247  

Theiler M, & Anderson CR. (1975) The relative resistance of dengue-immune monkeys to yellow fever virus. The American journal of tropical medicine and hygiene, 24(1), 115-7. PMID: 1111351  

  • June 10, 2016
  • 11:50 AM

Beetle Moms Make Anti-Aphrodisiac to Keep Dads Focused on Parenting

by Elizabeth Preston in Inkfish

"Not tonight, honey," says the female burying beetle, chewing up a mouthful of mouse carcass before spitting it into the mouth of a begging larva.

For the first few days of their babies' lives, burying beetles co-parent. They devote themselves to keeping their squirming larvae alive. That means mating and laying more eggs would be a waste of energy. And to make sure males get that message, females emit a pheromone that turns them off.

"It is quite surprising," says University of Ulm be... Read more »

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