Post List

  • November 28, 2016
  • 07:02 AM
  • 80 views

It’s late in 2016 and we still neither like nor trust atheists

by Doug Keene in The Jury Room

We’ve written about atheists here (and how unpopular they are in North America) a number of times. The first time was in 2010 when we wrote an article in The Jury Expert because we were so taken aback by the level of vitriol we’d seen in a blog post describing a new research article on […]

Related posts:
Everything you ever wanted to know about atheists  (the 2016 update)
An update on disrupting suspicion of atheists
Everyone knows you just can’t trust an atheist!


... Read more »

  • November 28, 2016
  • 04:51 AM
  • 136 views

Airplane Headache II: The Sequel

by The Neurocritic in The Neurocritic




Airline travel during the holidays is one big headache. But for some people, “airplane headache” is a truly painful experience. The headache occurs during take-off and landing, is unique to plane travel, and is not associated with other conditions. The pain is severe, with a jabbing or stabbing quality, and located on one side of the head (usually around the eye sockets or forehead).



... Read more »

Bui, S., Petersen, T., Poulsen, J., & Gazerani, P. (2016) Headaches attributed to airplane travel: a Danish survey. The Journal of Headache and Pain, 17(1). DOI: 10.1186/s10194-016-0628-7  

Headache Classification Committee of the International Headache Society (IHS). (2013) The International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia, 33(9), 629-808. DOI: 10.1177/0333102413485658  

  • November 28, 2016
  • 04:30 AM
  • 105 views

By Standing More at Work Do We Sit More at Home?

by Amanda Estep in Sports Medicine Research (SMR): In the Lab & In the Field

Sit-to-stand workstations is an effective strategy to decrease sedentary time and increase light activity time during working hours; however, during non-working hours more time was still spent sitting. ... Read more »

Mansoubi M, Pearson N, Biddle SJ, & Clemes SA. (2016) Using Sit-to-Stand Workstations in Offices: Is There a Compensation Effect?. Medicine and science in sports and exercise, 48(4), 720-5. PMID: 26496419  

  • November 28, 2016
  • 03:23 AM
  • 125 views

On moving off the autism spectrum

by Paul Whiteley in Questioning Answers

The paper by Nahit Motavalli Mukaddes and colleagues [1] provides some important, if small-scale, information when it comes to that still controversial term - optimal outcome - with the diagnosis of autism in mind. Optimal outcome basically refers to a particular 'type' of autism whereby following a definite diagnosis of autism or autism spectrum disorder (ASD), a later re-evaluation of signs and symptoms reveals that diagnostic thresholds are subsequently not reached and/or exceeded a........ Read more »

  • November 27, 2016
  • 04:16 PM
  • 101 views

Interview with Tunca Doğan, OMA Visiting Fellow 2016

by Christophe Dessimoz in Open Reading Frame

Note: the “Life in the Lab” series features interviews of interns and visitors. This post is by our second 2016 OMA Visiting Fellow Tunca Doğan, who spent a month with us earlier this year. You can follow Tunca on Twitter at @tuncadogan. —Christophe



Please introduce yourself in a few sentences.

My name is Tunca Doğan. I received my PhD in 2013 with a thesis study in the fields of bioinformatics and computational biology where we developed methods for the clustering........ Read more »

  • November 26, 2016
  • 04:33 AM
  • 134 views

Acetylation focus over methylation in autism epigenetics?

by Paul Whiteley in Questioning Answers

The paper by Wenjie Sun and colleagues [1] (open-access) provides the blogging fodder for today's post and although based on the science of epigenetics, the usual suspect - DNA methylation - gives way to another concept: histone acetylation with autism in mind. Before heading into the paper myself, I'll draw your attention to some other write-ups of the study including a hat-tip to Jeff Craig and his piece on the topic (see here).So histone acetylation... I've covered the subject ........ Read more »

Sun, W., Poschmann, J., Cruz-Herrera del Rosario, R., Parikshak, N., Hajan, H., Kumar, V., Ramasamy, R., Belgard, T., Elanggovan, B., Wong, C.... (2016) Histone Acetylome-wide Association Study of Autism Spectrum Disorder. Cell, 167(5), 1385-2147483647. DOI: 10.1016/j.cell.2016.10.031  

  • November 25, 2016
  • 08:00 PM
  • 133 views

Three mechanisms of dark selection for ruxolitinib resistance

by Artem Kaznatcheev in Evolutionary Games Group

Last week I returned from the 6th annual IMO Workshop at the Moffitt Cancer Center in Tampa, Florida. As I’ve sketched in an earlier post, my team worked on understanding ruxolitinib resistance in chronic myelomonocytic leukemia (CMML). We developed a suite of integrated multi-scale models for uncovering how resistance arises in CMML with no apparent […]... Read more »

Merlevede, J., Droin, N., Qin, T., Meldi, K., Yoshida, K., Morabito, M., Chautard, E., Auboeuf, D., Fenaux, P., Braun, T.... (2016) Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents. Nature Communications, 10767. PMID: 26908133  

  • November 25, 2016
  • 03:48 PM
  • 111 views

When Facing Predators, Male Monkeys Do Whatever Females Tell Them

by Elizabeth Preston in Inkfish



In the forests of West Africa, bands of handsome primates called Diana monkeys roam the tree branches. Each group has just one male and several females with their babies. The tradeoff for his apparently cushy living situation is that the male has to chase off predators. His female companions use specific calls to tell him what kinds of threats are nearby. And he responds to whatever they tell him—even if it goes against his own judgment.



Diana monkeys (Cercopithecus diana) of both sex... Read more »

  • November 25, 2016
  • 03:33 PM
  • 581 views

Is forefoot varus related to patellofemoral osteoarthritis?

by Craig Payne in Its a Foot Captain, But Not as You Know It

Is forefoot varus related to patellofemoral osteoarthritis?... Read more »

  • November 25, 2016
  • 06:40 AM
  • 133 views

FLCN haploinsufficiency leads to lung fibroblast dysfunction in patients with BHD syndrome

by Joana Guedes in BHD Research Blog

Birt–Hogg–Dubé syndrome (BHD) is caused by germline mutations in the FLCN gene and characterized by fibrofolliculomas, lung cysts, spontaneous pneumothorax and renal tumours. The stretch hypothesis for pulmonary cyst formation proposes that cysts in BHD arise from defects in cell–cell adhesion, leading to repeated respiration-induced physical stretch-induced stress and, over time, expansion of alveolar spaces particularly in vulnerable regions of lung (Kennedy et al., 20........ Read more »

Hoshika, Y., Takahashi, F., Togo, S., Hashimoto, M., Nara, T., Kobayashi, T., Nurwidya, F., Kataoka, H., Kurihara, M., Kobayashi, E.... (2016) Haploinsufficiency of the gene leads to impaired functions of lung fibroblasts in patients with Birt–Hogg–Dubé syndrome . Physiological Reports, 4(21). DOI: 10.14814/phy2.13025  

  • November 25, 2016
  • 05:00 AM
  • 128 views

Friday Fellow: Persian Carpet Flatworm

by Piter Boll in Earthling Nature

by Piter Kehoma Boll A flatworm again, at last! Not a land planarian, but a flatworm nonetheless. If there is a group of flatworms that may put land planarians in second plan regarding beauty, those are the polyclads. Living in … Continue reading →... Read more »

  • November 25, 2016
  • 02:49 AM
  • 155 views

Screening for coeliac disease in autism

by Paul Whiteley in Questioning Answers

"The overall CD [coeliac disease or celiac disease depending on where you live] prevalence was 2.62%, which is statistically significant higher to that reported in the Italian paediatric population... If replicated, these data suggest the importance of regular screening for CD in young patients with ASD [autism spectrum disorder]."Those were some of the findings/conclusions reported in the paper by Sara Calderoni and colleagues [1] (open-access) and with them, some ........ Read more »

Calderoni, S., Santocchi, E., Del Bianco, T., Brunori, E., Caponi, L., Paolicchi, A., Fulceri, F., Prosperi, M., Narzisi, A., Cosenza, A.... (2016) Serological screening for Celiac Disease in 382 pre-schoolers with Autism Spectrum Disorder. Italian Journal of Pediatrics, 42(1). DOI: 10.1186/s13052-016-0308-x  

  • November 24, 2016
  • 04:48 AM
  • 159 views

Breastfeeding and autism (or autistic traits) continued?

by Paul Whiteley in Questioning Answers

"After adjustment for several confounders, longer duration of breastfeeding was independently associated with better cognitive development and with fewer autistic traits."So said the paper by Olivier Boucher and colleagues [1] communicating findings based on the examination of data from "the INMA Project, a Spanish multicenter birth-cohort study" (an initiative that has cropped up on this blog before).Including over 1300 children who were subject to a battery of psychometric and behavioural asse........ Read more »

Boucher O, Julvez J, Guxens M, Arranz E, Ibarluzea J, Sánchez de Miguel M, Fernández-Somoano A, Tardon A, Rebagliato M, Garcia-Esteban R.... (2016) Association between breastfeeding duration and cognitive development, autistic traits and ADHD symptoms: a multicenter study in Spain. Pediatric research. PMID: 27846197  

  • November 23, 2016
  • 05:24 PM
  • 174 views

Interpreting English language ideologies in Korea: dreams vs. realities

by Lg_on_the_move in Language on the Move

Many people around the world dream of learning English. The pursuit of English is rarely only, or even predominantly, about language learning: it’s...... Read more »

  • November 23, 2016
  • 10:30 AM
  • 162 views

Pets May Help Children Learn About Animal Welfare

by CAPB in Companion Animal Psychology Blog

Children’s beliefs about animal welfare and sentience are linked to their own experiences with animals.Surprisingly little is known about children’s beliefs and knowledge about animals. Yet this information could help to improve humane education programs for children. Two recent studies begin to fill this gap, with recommendations for how humane education is taught.We know from previous research that even very young children like animals, and that children with pets are more likely to attrib........ Read more »

  • November 23, 2016
  • 07:00 AM
  • 139 views

Hypertriacylglycerolaemia: Genetic and epigenetic factors jointly regulate circulating triacylglycerol levels

by Iris Oliva Rodriguez in EpiBeat

Apolipoprotein A5 gene (APOA5) is one of the genes implicated in contributing to a predisposition for hypertriacylglycerolaemia (HTG), a complex polygenic pathology that is highly influenced by environment. Hypertriacylglycerolaemia is characterized by having high circulating triacylglycerol levels and is a significant risk factor for cardiovascular disease and atherosclerosis. This genetic predisposition has an inherited component (based on polymorphisms) as well as an acquired component regu........ Read more »

Oliva, I., Guardiola, M., Vallve, J., Ibarretxe, D., Plana, N., Masana, L., Monk, D., & Ribalta, J. (2016) APOA5 genetic and epigenetic variability jointly regulate circulating triacylglycerol levels. Clinical Science, 130(22), 2053-2059. DOI: 10.1042/CS20160433  

  • November 23, 2016
  • 04:30 AM
  • 157 views

Tape (or Wait) for Stabilizers to Activate

by Nicole Cattano in Sports Medicine Research (SMR): In the Lab & In the Field

Shoulder taping is associated with early activation of scapular muscles; however, this only resulted in a minimal effect on shoulder kinematics. ... Read more »

  • November 23, 2016
  • 04:29 AM
  • 170 views

ADHD symptoms not methylphenidate treatment might prime for psychotic events

by Paul Whiteley in Questioning Answers

"This study does not support the hypothesis that MPH [methylphenidate] increases risk of incident psychotic events. It does indicate an increased risk of psychotic events before the first prescription of MPH, which may be because of an association between psychotic events and the behavioural and attentional symptoms that led to psychiatric assessment and initiation of MPH treatment."The results published by Man and colleagues [1] (open-access) sit right with me. I say that on the basis........ Read more »

Man, K., Coghill, D., Chan, E., Lau, W., Hollis, C., Liddle, E., Banaschewski, T., McCarthy, S., Neubert, A., Sayal, K.... (2016) Methylphenidate and the risk of psychotic disorders and hallucinations in children and adolescents in a large health system. Translational Psychiatry, 6(11). DOI: 10.1038/tp.2016.216  

  • November 22, 2016
  • 07:03 AM
  • 175 views

Energetic electrons generated during solar flares by Gottfried Mann

by CESRA in Solar Radio Science

The Sun is an active star. It manifests not only in everybody’s well-known Sun spots with the related 11-year cycle. This activity manifests not only as the well-known sun spot phenomenon with a related 11-year cycle, but also in flares, coronal mass ejections (CMEs), and solar energetic particle (SEP) events. Thus, [...]... Read more »

Gottfried Mann. (2016) Energetic electrons generated during solar flares. Journal of Plasma Physics. info:/

  • November 22, 2016
  • 03:43 AM
  • 165 views

Interview with Rosa Fernández, 2016 OMA Visiting Fellow

by Christophe Dessimoz in Open Reading Frame

Note: We are rebooting our “Life in the Lab” series, which features interviews of interns and visitors. This post is by our inaugural OMA Visiting Fellow Rosa Fernández García, who spent a month with us earlier this year. You can follow Rosa on Twitter at @Rosamygale. —Christophe

 

Please introduce yourself and your research interests.

I received my bachelor’s degree in Biology (major in Zoology) at Complutense University in Madrid, Spain. I got my master’s and PhD at the s........ Read more »

Fernández R, Laumer CE, Vahtera V, Libro S, Kaluziak S, Sharma PP, Pérez-Porro AR, Edgecombe GD, & Giribet G. (2014) Evaluating topological conflict in centipede phylogeny using transcriptomic data sets. Molecular biology and evolution, 31(6), 1500-13. PMID: 24674821  

Novo M, Fernández R, Andrade SC, Marchán DF, Cunha L, & Díaz Cosín DJ. (2016) Phylogenomic analyses of a Mediterranean earthworm family (Annelida: Hormogastridae). Molecular phylogenetics and evolution, 94(Pt B), 473-8. PMID: 26522608  

Sharma, P., Fernandez, R., Esposito, L., Gonzalez-Santillan, E., & Monod, L. (2015) Phylogenomic resolution of scorpions reveals multilevel discordance with morphological phylogenetic signal. Proceedings of the Royal Society B: Biological Sciences, 282(1804), 20142953-20142953. DOI: 10.1098/rspb.2014.2953  

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