MedicalResearch.com Interview with: Tae-Hyun Yoo MD PhD Department of Internal Medicine, College of Medicine Severance Biomedical Science Institute, Brain Korea 21 PLUS Yonsei University, Seoul, Korea Medical Research: What is the background for this study? What are the main findings? … Continue reading →
The post Protein Irisin Linked to Muscle Wasting and Atherosclerosis in Dialysis Patients appeared first on MedicalResearch.com Medical Research Interviews and News.
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Tae-Hyun Yoo MD PhD. (2015) Protein Irisin Linked to Muscle Wasting and Atherosclerosis in Dialysis Patients. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Sandrine Colas, MSc, MPH Department of Epidemiology of Health Products French National Agency for Medicines and Health Products Safety (ANSM) Saint-Denis, France Medical Research: What is the background for this study? What are the main findings? Response: Total hip … Continue reading →
The post Factors Identified For Lasting Total Hip Replacement appeared first on MedicalResearch.com Medical Research Interviews and News.
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Sandrine Colas, MSc, MPH. (2015) Factors Identified For Lasting Total Hip Replacement. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Bjarne Linde Norgaard, MD PhD Department of Cardiology, Aarhus University Hospital Skejby Aarhus, Denmark Medical Research: What is the background for this study? What are the main findings? Dr. Norgaard: Noninvasive fractional flow reserve derived from … Continue reading →
The post Noninvasive FFR Study Superior to CT Angiography In Patients With Highly Calcified Coronary Disease appeared first on MedicalResearch.com Medical Research Interviews........ Read more »
Bjarne Linde Norgaard, MD PhD. (2015) Noninvasive FFR Study Superior to CT Angiography In Patients With Highly Calcified Coronary Disease. MedicalResearch.com. info:/
MedicalResearch.com Interview with: David B. Weiner, Ph.D. Professor, Department of Pathology and Laboratory Medicine Chair, Gene Therapy and Vaccine Program, CAMB Co-Leader Tumor Virology Program, Abramson Cancer Program University of Pennsylvania, Perelman School of Medicine Medical Research: What is the background … Continue reading →
The post Novel DNA Vaccine Provides Protection Against MERS Virus appeared first on MedicalResearch.com Medical Research Interviews and News.
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David B. Weiner, Ph.D. (2015) Novel DNA Vaccine Provides Protection Against MERS Virus. MedicalResearch.com. info:/
I'd like to briefly draw your attention to the review published by Elizabeth DeVilbiss and colleagues  today, covering "what is known about the role of folate in the aetiology of neurodevelopmental disorders."Folate, is a topic that has graced this blog a few times with autism in mind (see here for example) based on various ideas that folate status during pregnancy might have the ability to modify offspring risk of autism  alongside the idea that autoimmune processes might act on fola........ Read more »
DeVilbiss EA, Gardner RM, Newschaffer CJ, & Lee BK. (2015) Maternal folate status as a risk factor for autism spectrum disorders: a review of existing evidence. The British journal of nutrition, 1-10. PMID: 26243379
MedicalResearch.com Interview with: Gary S. Marshall, M.D. Professor of Pediatrics Chief, Division of Pediatric Infectious Diseases Director, Pediatric Clinical Trials Unit University of Louisville School of Medicine Medical Research: What is the background for this study? What are … Continue reading →
The post Single Vaccine Can Protect Against Six Common Childhood Diseases appeared first on MedicalResearch.com Medical Research Interviews and News.
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Gary S. Marshall, M.D. (2015) Single Vaccine Can Protect Against Six Common Childhood Diseases. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Hendrik Marks Ph.D Group leader Epigenetics of Stem Cells Radboud University, Department of Molecular Biology, RIMLS Nijmegen, The Netherlands Medical Research: What is the background for this study? What are the main findings? Dr. Marks: In mammals, … Continue reading →
The post How Do Female Cells Inactivate One X Chromosome? appeared first on MedicalResearch.com Medical Research Interviews and News.
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Hendrik Marks Ph.D. (2015) How Do Female Cells Inactivate One X Chromosome?. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Lainie Rutkow, JD, PhD, MPH Associate Professor Department of Health Policy and Management Johns Hopkins Bloomberg School of Public Health Medical Research: What is the background for this study? What are the main findings? Dr. Rutkow: Rates … Continue reading →
The post Florida’s Drug and Pill Mills Law Reduced Opioids Prescriptions appeared first on MedicalResearch.com Medical Research Interviews and News.
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Lainie Rutkow, JD, PhD, MPH. (2015) Florida's Drug and Pill Mills Laws Reduced Opioids Prescriptions. MedicalResearch.com. info:/
In human cells, shortened telomeres, the protective caps at the ends of chromosomes, are both a sign of aging and contribute to it. Scientists have found that the dietary supplement alpha lipoic acid (ALA) can stimulate telomerase, the enzyme that lengthens telomeres, with positive effects in a mouse model of atherosclerosis.... Read more »
Xiong, S., Patrushev, N., Forouzandeh, F., Hilenski, L., & Alexander, R. (2015) PGC-1α Modulates Telomere Function and DNA Damage in Protecting against Aging-Related Chronic Diseases. Cell Reports. DOI: 10.1016/j.celrep.2015.07.047
Hungry mosquitoes use an arsenal of sensory tools to hunt you down. They sniff out the carbon dioxide you exhale; they home in on your heat signature. But a previously under-appreciated tool in the mosquito's kit is the same one you use just before slapping at it in horror: vision.
At Caltech, Floris van Breugel put mosquitoes in a wind tunnel to tease apart how they find their meals. He used Aedes aegypti, a tropical species that spreads yellow fever and other diseases. The insects wer........ Read more »
van Breugel, F., Riffell, J., Fairhall, A., & Dickinson, M. (2015) Mosquitoes Use Vision to Associate Odor Plumes with Thermal Targets. Current Biology, 25(16), 2123-2129. DOI: 10.1016/j.cub.2015.06.046
MedicalResearch.com Interview with: Ben Domingue Assistant Professor (starting 9/2015) Stanford Graduate School of Education Medical Research: What is the background for this study? What are the main findings? Response: Earlier research has started to illuminate which genetic … Continue reading →
The post Polygenetic Score Predicts Educational Attainment appeared first on MedicalResearch.com Medical Research Interviews and News.
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Ben Domingue. (2015) Polygenetic Score Predicts Educational Attainment. MedicalResearch.com. info:/
Folliculin interaction protein 1 (FNIP1), through interactions with FLCN, plays a role in a range of cellular processes (Baba et al., 2006). Alternative splicing of FNIP1, under the control of MBNL1, was previously reported in late mesenchymal differentiation (Venables et al., 2013). New research from De Conti et al., (2015) has identified FNIP1 as also being differentially spliced by TDP-43 – a protein associated with neurodegeneration in ALS and fronto-temporal dementia (Neumann et al., ........ Read more »
De Conti L, Akinyi MV, Mendoza-Maldonado R, Romano M, Baralle M, & Buratti E. (2015) TDP-43 affects splicing profiles and isoform production of genes involved in the apoptotic and mitotic cellular pathways. Nucleic acids research. PMID: 26261209
In most areas of life, we expect the free versions of products to be sub-standard compared with the "premium" paid-for versions. After all, why would anyone pay for something if the free equivalent were better? However, a new study of personality tests boots this logic off the park – psychologists at the University of Texas report in the Journal of Psychology that free tests are more reliable and efficient than their paid-for, proprietary counterparts.To measure test reliability, Tyler Ha........ Read more »
Hamby, T., Taylor, W., Snowden, A., & Peterson, R. (2015) A Meta-Analysis of the Reliability of Free and For-Pay Big Five Scales. The Journal of Psychology, 1-12. DOI: 10.1080/00223980.2015.1060186
"The ASD [autism spectrum disorder] group receiving digestive enzyme therapy for 3 months had significant improvement in emotional response, general impression autistic score, general behavior and gastrointestinal symptoms. Our study demonstrated the usefulness of digestive enzyme in our population of ASD patients."So said the results of a randomised, placebo-controlled clinical trial published by Khaled Saad and colleagues  (open-access available here) on the use of a specific dige........ Read more »
Saad K, Eltayeb AA, Mohamad IL, Al-Atram AA, Elserogy Y, Bjørklund G, El-Houfey AA, & Nicholson B. (2015) A Randomized, Placebo-controlled Trial of Digestive Enzymes in Children with Autism Spectrum Disorders. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, 13(2), 188-93. PMID: 26243847
This paper investigates the scope for resilience indicators to predict an upcoming stock collapse. We find that economic information, such as profits, may complement biological information when assessing the state of fisheries.
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Richter, A., & Dakos, V. (2015) Profit fluctuations signal eroding resilience of natural resources. Ecological Economics, 12-21. DOI: 10.1016/j.ecolecon.2015.05.013
Ostrom, E. (1999) Revisiting the Commons: Local Lessons, Global Challenges. Science, 284(5412), 278-282. DOI: 10.1126/science.284.5412.278
Dakos, V., Carpenter, S., van Nes, E., & Scheffer, M. (2014) Resilience indicators: prospects and limitations for early warnings of regime shifts. Philosophical Transactions of the Royal Society B: Biological Sciences, 370(1659), 20130263-20130263. DOI: 10.1098/rstb.2013.0263
Richter, A., van Soest, D., & Grasman, J. (2013) Contagious cooperation, temptation, and ecosystem collapse. Journal of Environmental Economics and Management, 66(1), 141-158. DOI: 10.1016/j.jeem.2013.04.004
MedicalResearch.com Interview with: Edward Hill PhD student Centre for Complexity Science Member of the Warwick Infectious Disease Epidemiology Research Centre (WIDER) at the University of Warwick Medical Research: What is the background for this study? Response: Depression is a major public health … Continue reading →
The post Fortunately, Good Moods Are Contagious But Depression Is Not appeared first on MedicalResearch.com Medical Research Interviews and News.
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Edward Hill PhD student. (2015) Fortunately, Good Moods Are Contagious But Depression Is Not. MedicalResearch.com. info:/
Old writings spanning the last four hundred years have been discovered in China that detail eras of drought. Using these as a starting point, researchers have connected the time periods with changes in rainfall to predict future droughts in the region.... Read more »
Tan, L., Cai, Y., An, Z., Cheng, H., Shen, C., Breitenbach, S., Gao, Y., Edwards, R., Zhang, H., & Du, Y. (2015) A Chinese cave links climate change, social impacts, and human adaptation over the last 500 years. Scientific Reports, 12284. DOI: 10.1038/srep12284
Disease-causing viruses engage their hosts in ongoing arms races: positive selection for antiviral genes increases host fitness and survival, and viruses in turn select for mutations that counteract the antiviral host factors. Studying such adaptive mutations can provide insights into the distant history of host-virus interactions. A study of antiviral gene sequences in African monkeys suggests that lentiviruses closely related to HIV have infected primates in Africa as far back as 16 million ye........ Read more »
Kevin R. McCarthy, Andrea Kirmaier, Patrick Autissier, & Welkin E. Johnson. (2015) Evolutionary and Functional Analysis of Old World Primate TRIM5 Reveals the Ancient Emergence of Primate Lentiviruses and Convergent Evolution Targeting a Conserved Capsid Interface. PLOS Pathogens. info:/10.1371/journal.ppat.1005085
Sometimes I read a paper because the methods catch my eye. I can just imagine some scientists sitting around a table with a beer and saying, “I wonder what would happen if we just dropped a bunch of spiders from the tops of trees.” An article published online yesterday did just that.Barro Colorado Island is a man-made island is located in Gatun Lake, created by filling of the Panama Canal. It is covered in tropical rainforests, and its inhabitants have been studied extensively. It would be a........ Read more »
Stephen P. Yanoviak, Yonatan Munk, & Robert Dudley. (2015) Arachnid aloft: directed aerial descent in neotropical canopy spiders. J. R. Soc. Interface. info:/10.1098/rsif.2015.0534
The hippocampus in the brain’s temporal lobe is responsible for more than just long-term memory. Researchers have for the first time demonstrated that it is also involved in quick and successful conflict resolution.... Read more »
C.R. Oehrn, C. Baumann, J. Fell, H. Lee, H. Kessler, U. Habel, S. Hanslmayr, & N. Axmacher. (2015) Human hippocampal dynamics during response conflict. Current Biology. info:/10.1016/j.cub.2015.07.032
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