Post List

  • July 14, 2014
  • 05:02 AM
  • 78 views

Joint hypermobility, gait and autism

by Paul Whiteley in Questioning Answers

I have already made mention of the paper by Maya Shetreat-Klein and colleagues [1] on this blog as part of a post on the potential usefulness of kata training for at least some people on the autism spectrum (see here). Based on an analysis of 38 children diagnosed with autism spectrum disorder (ASD) and a similar number of asymptomatic controls (all medication free), researchers set about recording "the characteristics of gait and prevalence of toe walking, the range of passive joint mobility, a........ Read more »

  • July 14, 2014
  • 12:05 AM
  • 63 views

Pitching: We Can Have too Much of a Good Thing

by Mark Rice in Sports Medicine Research (SMR): In the Lab & In the Field

Young pitchers who engage in “risk-prone” pitching activities are more likely to report arm tiredness and pain, which is related to shoulder and elbow injuries.... Read more »

Yang, J., Mann, B., Guettler, J., Dugas, J., Irrgang, J., Fleisig, G., & Albright, J. (2014) Risk-Prone Pitching Activities and Injuries in Youth Baseball: Findings From a National Sample. The American Journal of Sports Medicine, 42(6), 1456-1463. DOI: 10.1177/0363546514524699  

  • July 13, 2014
  • 08:53 PM
  • 60 views

Photosynthesis in action: new technique resolves atomic changes in undamaged photosystems

by Jonathan Trinastic in Goodnight Earth

A new experimental technique allows scientists to see conformational changes in photosynthetic systems without damaging the samples!... Read more »

Kupitz, C., Basu, S., Grotjohann, I., Fromme, R., Zatsepin, N., Rendek, K., Hunter, M., Shoeman, R., White, T., Wang, D.... (2014) Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser. Nature. DOI: 10.1038/nature13453  

  • July 13, 2014
  • 03:15 PM
  • 81 views

New ways to test for Alzheimers

by Gabriel in Lunatic Laboratories

Accurately diagnosing alzheimer’s is not an easy thing to do. In fact most of the time people aren’t diagnosed until very late in the progression of the disease, long after […]... Read more »

Matthew E Growdon,, Aaron Schultz,, Alexander Dagley,, Rebecca Amariglio,, Trey Hedden,, Dorene M. Rentz,, Keith Johnson,, Reisa Sperling,, Mark W. Albers,, & Gad Marshall,. (2014) Olfactory identification and Alzheimer's disease biomarkers in clinically normal elderly. Nature Neuroscience. info:/

  • July 13, 2014
  • 09:23 AM
  • 80 views

Language and handedness

by Janet Kwasniak in Neuro-patch

  I am both left handed and dyslexic and so a recent paper on the connection in hemispheric dominance for hand and for language was a paper I had to read. The Mazoyer study seems to be the first to use a reasonable number of left- and as well as right-handed people to look at […]... Read more »

  • July 13, 2014
  • 05:21 AM
  • 4 views

Hotter, Smarter, Better Brains

by Viputheshwar Sitaraman in Draw Science

It is evident that (a) higher body temperature leads to higher brain performance and (b) the sames holds true in an evolutionary context in terms of brain size. So hotter = smarter?... Read more »

James F. Gillooly. (2013) Hotter is Smarter: The temperature-dependence of brain size in vertebrates. PeerJ. info:/10.7287/peerj.preprints.155v1

Wright KP Jr, Hull JT, & Czeisler CA. (2002) Relationship between alertness, performance, and body temperature in humans. American journal of physiology. Regulatory, integrative and comparative physiology, 283(6). PMID: 12388468  

  • July 12, 2014
  • 07:02 PM
  • 92 views

Legal highs – not for human consumption

by DJMac in Recovery Review

Legal highs in Lothian The UK has the largest market for new psychoactive substances (NSP or “legal highs”) in Europe. Scotland is no stranger to them and, as a seminar in Edinburgh heard last week, the Lothian area is seeing a surge in demand, some worrying trends in injecting and significant new presentations due to problems [...]
The post Legal highs – not for human consumption appeared first on Recovery Review.
... Read more »

  • July 12, 2014
  • 05:59 PM
  • 86 views

Barefoot running survey: Evidence from the field???

by Craig Payne in Running Research Junkie

Barefoot running survey: Evidence from the field???... Read more »

Hryvniak, D., Dicharry, J., & Wilder, R. (2014) Barefoot running survey: Evidence from the field. Journal of Sport and Health Science, 3(2), 131-136. DOI: 10.1016/j.jshs.2014.03.008  

  • July 12, 2014
  • 01:59 PM
  • 115 views

Infant once thought Cured of HIV tests Positive

by Gabriel in Lunatic Laboratories

I hate doing sad posts, it’s not my thing. But this is a big deal so I thought I would share it, the child known as the “Mississippi baby” – whom for […]... Read more »

Persaud, D., Gay, H., Ziemniak, C., Chen, Y., Piatak, M., Chun, T., Strain, M., Richman, D., & Luzuriaga, K. (2013) Absence of Detectable HIV-1 Viremia after Treatment Cessation in an Infant. New England Journal of Medicine, 369(19), 1828-1835. DOI: 10.1056/NEJMoa1302976  

  • July 12, 2014
  • 01:42 PM
  • 120 views

Media and the Mind: Emotional Contagion

by JBSheppard in Antisense Science

Facebook recently carried out an experiment to change the emotions of over 600,000 users through a known psychological process called "emotional contagion". ... Read more »

  • July 12, 2014
  • 11:36 AM
  • 103 views

Organic food: meta-analysed

by Paul Whiteley in Questioning Answers

A very quick post to direct you to the paper by Barański and colleagues [1] which is currently making a few headlines and sparking some debate (see here and see here) with their assertions: "the concentrations of a range of antioxidants such as polyphenolics were found to be substantially higher in organic crops/crop-based foods" and "the frequency of occurrence of pesticide residues was found to be four times higher in conventional crops, which also contained significantly higher con........ Read more »

  • July 12, 2014
  • 06:50 AM
  • 88 views

Could climate’s crop impact catch us with our plants down?

by Andy Extance in Simple Climate

Global warming has sharply increased the odds of serious problems because of declining harvests, find David Lobell from and Claudia Tebaldi from NCAR, and though that situation remains fairly unlikely, they advise countries to prepare for it. ... Read more »

Mora, C., Frazier, A., Longman, R., Dacks, R., Walton, M., Tong, E., Sanchez, J., Kaiser, L., Stender, Y., Anderson, J.... (2013) The projected timing of climate departure from recent variability. Nature, 502(7470), 183-187. DOI: 10.1038/nature12540  

Hawkins, E., Anderson, B., Diffenbaugh, N., Mahlstein, I., Betts, R., Hegerl, G., Joshi, M., Knutti, R., McNeall, D., Solomon, S.... (2014) Uncertainties in the timing of unprecedented climates. Nature, 511(7507). DOI: 10.1038/nature13523  

  • July 12, 2014
  • 04:31 AM
  • 135 views

Gold standard addiction treatment

by DJMac in Recovery Review

  Gold standard addiction treatment Addiction to alcohol or other drugs is not easy to recover from. However there are many pathways to recovery, including through treatment. One group of patients does far better than most other groups. In fact their results are so impressive that many commentators have urged us to learn from what’s [...]
The post Gold standard addiction treatment appeared first on Recovery Review.
... Read more »

DuPont, R., McLellan, A., White, W., Merlo, L., & Gold, M. (2009) Setting the standard for recovery: Physicians' Health Programs. Journal of Substance Abuse Treatment, 36(2), 159-171. DOI: 10.1016/j.jsat.2008.01.004  

  • July 12, 2014
  • 02:29 AM
  • 126 views

Night-to-night variability of sleep in traumatic brain injury

by William Lu in The Quantum Lobe Chronicles

It's been a while since I've posted something substantial. My apologies to all 20 followers of TQLC. Academia and clinical cases have been taking up most of my time. However, some exciting news! My paper on variability of respiration during sleep in traumatic brain injury (TBI) has recently been accepted into Neurorehabilitation. In the paper my colleagues and I examined the sleep processes of individuals with TBI using polysomnography. Polysomnography is a tool used to measure biophysical ch........ Read more »

Lu W, Cantor J, Aurora RN, Nguyen M, Ashman T, Spielman L, Ambrose A, Krellman J, & Gordon W. (2014) Variability of respiration and sleep during polysomnography in individuals with TBI. NeuroRehabilitation. PMID: 24990025  

  • July 11, 2014
  • 04:33 PM
  • 116 views

Coronavirus nsp-6 and the inhibition of autophagy

by thelonevirologist in Virology Tidbits

The Coronaviridae, which include viruses capable of infecting animals as well as humans, belong to order of the Nidovirales and as such are enveloped positive strand ssRNA viruses.
As described before, they induce the formation of Replication Transcription Complexes (RTCs), essentially double membrane vesicles (DMVs) derived from the ER containing enzymes and viral RNA. The biogenesis of these DMVs has been connected with the early secretory pathway and involves components of the autophagic p........ Read more »

Fujita N, Itoh T, Omori H, Fukuda M, Noda T, & Yoshimori T. (2008) The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Molecular biology of the cell, 19(5), 2092-100. PMID: 18321988  

Liu, D., Fung, T., Chong, K., Shukla, A., & Hilgenfeld, R. (2014) Accessory proteins of SARS-CoV and other coronaviruses. Antiviral Research. DOI: 10.1016/j.antiviral.2014.06.013  

Cottam EM, Whelband MC, & Wileman T. (2014) Coronavirus NSP6 restricts autophagosome expansion. Autophagy, 10(8). PMID: 24991833  

Flinn RJ, Yan Y, Goswami S, Parker PJ, & Backer JM. (2010) The late endosome is essential for mTORC1 signaling. Molecular biology of the cell, 21(5), 833-41. PMID: 20053679  

Li L, Kim E, Yuan H, Inoki K, Goraksha-Hicks P, Schiesher RL, Neufeld TP, & Guan KL. (2010) Regulation of mTORC1 by the Rab and Arf GTPases. The Journal of biological chemistry, 285(26), 19705-9. PMID: 20457610  

  • July 11, 2014
  • 04:11 PM
  • 127 views

Antioxidants can accelerate Cancer, ya really!

by Gabriel in Lunatic Laboratories

Oxidative stress on the body caused by free radicals, billed as a bad thing. Fruits, veggies and just about anything with the word healthy in the title is “jam packed” […]... Read more »

Phimister, E., Chandel, N., & Tuveson, D. (2014) The Promise and Perils of Antioxidants for Cancer Patients. New England Journal of Medicine, 371(2), 177-178. DOI: 10.1056/NEJMcibr1405701  

  • July 11, 2014
  • 02:38 PM
  • 122 views

Can one daily drink of alcohol increase risk of heart disease? . . . really?

by AB Kirk in Stiff Competition

Can one drink of alcohol increase risk of heart disease?  Reporters are saying a new study says “Yes”.  Many people have been advised through print or conversation that a daily glass of wine or beer is a healthy practice. And it might be for some. Many studies have found a longer lifespan in people who […]
The post Can one daily drink of alcohol increase risk of heart disease? . . . really? appeared first on WODMasters: Stiff Competition.
... Read more »

  • July 11, 2014
  • 01:45 PM
  • 132 views

Change your Genes with Stem Cells!

by Gabriel in Lunatic Laboratories

So researchers for the first time were evaluating the safety and reliability of the existing targeted gene correction technologies and in the process they successfully developed a new method of gene […]... Read more »

  • July 11, 2014
  • 10:22 AM
  • 121 views

Ye Old Science Journal. Interesting articles from the premiere journal of 1880.

by The Lab Hippo in The Lab Hippo

One of the perks to my job is that I can get access to just about any journal article I want for free. I know, it sounds like a dream life, but hey you go to college for 10 years and you get some favors thrown your way. A few years ago Science scanned all their historical archives put them online, so I begun to peruse a few and was pleasantly amused. In what may become a recurring theme to the LabHippo, I now present to you some of the more entertaining articles. We begin with the first year Sci........ Read more »

  • July 11, 2014
  • 10:21 AM
  • 109 views

Part 2. Epigenetics. Rat Tounges & Ham Sandwiches Can Influence Children

by The Lab Hippo in The Lab Hippo

Picture your parents having sex. No..no good, too weird? OK then, picture your grandparents having sex. Even weirder? Fine, picture your great-grandparents having sex. That one might not be as bad. Chances are you never met your great-grandparents, which makes them somewhat strangers to you. You had eight great-grandparents and though you might not even know their names, about 12.5 percent of your DNA was inherited from them. Now imagine your great-grandmother eating a ham sandwich while having ........ Read more »

Pembrey, M., Bygren, L., Kaati, G., Edvinsson, S., Northstone, K., Sjöström, M., & Golding, J. (2005) Sex-specific, male-line transgenerational responses in humans. European Journal of Human Genetics, 14(2), 159-166. DOI: 10.1038/sj.ejhg.5201538  

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