Post List

  • November 19, 2014
  • 06:29 AM

Do you remember the time? How collective nostalgia inspires group loyalty

by BPS Research Digest in BPS Research Digest

Nostalgia seems like a distraction in a world that’s moving forward. But new research proposes a powerful function of the emotion: as a glue to bind members of social groups.Students from the University of Southampton recalled and wrote about an experience either involving other students, or where they were alone. They were either asked to choose an ordinary event or one that triggered nostalgic feeling, defined in the instructions as "sentimental longing for the past".Next they were asked how........ Read more »

Wildschut, T., Bruder, M., Robertson, S., van Tilburg, W., & Sedikides, C. (2014) Collective nostalgia: A group-level emotion that confers unique benefits on the group. Journal of Personality and Social Psychology, 107(5), 844-863. DOI: 10.1037/a0037760  

  • November 19, 2014
  • 06:21 AM

Why Cancer Doesn’t Favor Large Animals

by Gunnar de Winter in United Academics

Most cancers have their origin in the buildup of harmful mutations, so every active cell is at risk of unwittingly transforming into a murderer. Stands to reason then, that long-living animals with lots of cells should be more prone to succumb to the blight of cancer.... Read more »

  • November 19, 2014
  • 04:57 AM

Down Syndrome Disintegrative Disorder

by Paul Whiteley in Questioning Answers

"Down syndrome disintegrative disorder seems an appropriate name for this newly recognized clinical association, which may be due to autoimmunity.""Hi, everyone. I'm Olaf and I like warm hugs!"That was the bottom line of the study published by Gordon Worley and colleagues [1] reviewing a small number of cases (N=11) of children diagnosed with Down's syndrome presenting at clinic "with a history of new-onset... or worsening... autistic characteristics" among other things. Based on some potentiall........ Read more »

  • November 19, 2014
  • 12:05 AM

Are They Really up to the Task or is it Just Sandbagging?

by Kyle Harris in Sports Medicine Research (SMR): In the Lab & In the Field

Among athletes with an invalid computerized neurocognitive test at baseline, 87% received valid scores upon reassessment, which suggests reassessment can be used to gain a valid baseline score.... Read more »

Schatz, P., Kelley, T., Ott, S., Solomon, G., Elbin, R., Higgins, K., & Moser, R. (2014) Utility of Repeated Assessment After Invalid Baseline Neurocognitive Test Performance. Journal of Athletic Training, 49(5), 659-664. DOI: 10.4085/1062-6050-49.3.37  

  • November 18, 2014
  • 09:29 PM

Is There Such a Thing as ‘Facebook Murder’?

by Wiley Asia Blog in Wiley Asia Blog - Social Science

Investigators recently set out to consider whether homicides involving social networking sites were unique and worthy of labels such as ‘Facebook Murder’, and to explore the ways in which perpetrators had used such sites in the homicides they had committed.

The cases they identified were not collectively unique or unusual when compared with general trends and characteristics—certainly not to a degree that would necessitate the introduction of a new category of homicide or a ........ Read more »

  • November 18, 2014
  • 06:08 PM

HIV-1 and autophagy: Gag, Nef, and Tat

by thelonevirologist in Virology Tidbits

Patients infected with a virus that harbours a deletion of the nef gene either do not progress to full blown AIDS or -if so- with a considerable delay compared to patients infected with “standard” HIV as well as lower virus loads, suggesting that the expression of Nef is necessary for maintaining high viral loads and AIDS pathogenicity. In addition, deletions of nef within the genome of the simian equivalent of HIV, SIV, have similar effects in Rhesus monkeys. In general, Nef is bel........ Read more »

Kyei GB, Dinkins C, Davis AS, Roberts E, Singh SB, Dong C, Wu L, Kominami E, Ueno T, Yamamoto A.... (2009) Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages. The Journal of cell biology, 186(2), 255-68. PMID: 19635843  

Shoji-Kawata S, Sumpter R, Leveno M, Campbell GR, Zou Z, Kinch L, Wilkins AD, Sun Q, Pallauf K, MacDuff D.... (2013) Identification of a candidate therapeutic autophagy-inducing peptide. Nature, 494(7436), 201-6. PMID: 23364696  

Geist MM, Pan X, Bender S, Bartenschlager R, Nickel W, & Fackler OT. (2014) Heterologous Src homology 4 domains support membrane anchoring and biological activity of HIV-1 Nef. The Journal of biological chemistry, 289(20), 14030-44. PMID: 24706755  

Dinkins, C., Pilli, M., & Kehrl, J. (2014) Roles of autophagy in HIV infection. Immunology and Cell Biology. DOI: 10.1038/icb.2014.88  

Dinkins, C., Arko-Mensah, J., & Deretic, V. (2010) Autophagy and HIV. Seminars in Cell , 21(7), 712-718. DOI: 10.1016/j.semcdb.2010.04.004  

Yang YP, Hu LF, Zheng HF, Mao CJ, Hu WD, Xiong KP, Wang F, & Liu CF. (2013) Application and interpretation of current autophagy inhibitors and activators. Acta pharmacologica Sinica, 34(5), 625-35. PMID: 23524572  

Kang R, Zeh HJ, Lotze MT, & Tang D. (2011) The Beclin 1 network regulates autophagy and apoptosis. Cell death and differentiation, 18(4), 571-80. PMID: 21311563  

Bruno, A., De Simone, F., Iorio, V., De Marco, M., Khalili, K., Sariyer, I., Capunzo, M., Nori, S., & Rosati, A. (2014) HIV-1 Tat protein induces glial cell autophagy through enhancement of BAG3 protein levels. Cell Cycle. DOI: 10.4161/15384101.2014.952959  

Romani B, Engelbrecht S, & Glashoff RH. (2010) Functions of Tat: the versatile protein of human immunodeficiency virus type 1. The Journal of general virology, 91(Pt 1), 1-12. PMID: 19812265  

  • November 18, 2014
  • 05:14 PM

Does brain training really work?

by Gabriel in Lunatic Laboratories

Ever wonder if you could be the next Einstein if only you could do some brain training? Well as it turns out, while computer based ‘brain training’ can boost memory and thinking skills in older adults, many programs promoted by the $1 billion brain training industry are ineffective.... Read more »

  • November 18, 2014
  • 01:15 PM

From H. pylori to Spanish colonialism: the scales of cancer.

by Artem Kaznatcheev in Evolutionary Games Group

Yesterday was the first day of the 4th Integrated Mathematical Oncology Workshop here at Moffitt. This year, it is run jointly with the Center for Infection Research in Cancer and is thus focused on the interaction of infection disease and cancer. This is a topic that I have not focused much attention on — except […]... Read more »

Kodaman, N., Pazos, A., Schneider, B.G., Piazuelo, M.B., Mera, R., Sobota, R.S., Sicinschi, L.A., Shaffer, C.L., Romero-Gallo, J., de Sablet, T.... (2014) Human and Helicobacter pylori coevolution shapes the risk of gastric disease. Proceedings of the National Academy of Sciences of the United States of America, 111(4), 1455-60. PMID: 24474772  

  • November 18, 2014
  • 12:01 PM

Social Effectiveness Therapy Beats Social Anxiety, Study Shows

by Simon Moesgaard-Kjeldsen in Reflectd

A new randomized controlled trial shows promising results for the treatment of social anxiety disorder.... Read more »

Beidel, D., Alfano, C., Kofler, M., Rao, P., Scharfstein, L., & Wong Sarver, N. (2014) The impact of social skills training for social anxiety disorder: A randomized controlled trial. Journal of Anxiety Disorders, 28(8), 908-918. DOI: 10.1016/j.janxdis.2014.09.016  

  • November 18, 2014
  • 08:00 AM

This Is Your TV On Drugs

by Mark E. Lasbury in The 'Scope

There are more than 100 drug commercials on TV every hour of every day. Why? Because they work. Research shows that advertised drugs are prescribed 9x more than comparable drugs that aren’t advertised. And all those side effect notices? The drug companies like them because research says that all you remember is that they were “honest” with you.... Read more »

  • November 18, 2014
  • 07:02 AM

Feel like I-dosing? [Part 2]

by Henkjan Honing in Music Matters

"Digital drugs," otherwise known as binaural beats, have sparked an outcry in Lebanon, with the Justice Minister Ashraf Rifi calling Thursday for legal measures to be taken against the product...... Read more »

  • November 18, 2014
  • 04:52 AM

Paediatric congenital heart disease and autism risk?

by Paul Whiteley in Questioning Answers

"Children aged 2-17 with CHD [congenital heart disease] were more likely than those without CHD to have had a diagnosis of autism spectrum disorder (crude OR, 4.6; 95% CI, 1.9-11.0) or intellectual disability (Crude OR, 9.1; 95% CI, 5.4-15.4)".The traveller @ Wikipedia That was a key conclusion reported in the study by Hilda Razzaghi and colleagues [1] based on their analysis of data from "the 1997-2011 National Health Interview Survey", a US initiative which aims to pro........ Read more »

  • November 18, 2014
  • 12:05 AM

Psychological Strategies Effectively Reduce Perceived and Physiological Markers of Stress

by Caitlin Dios & Bryan Pope in Sports Medicine Research (SMR): In the Lab & In the Field

Both cognitive and somatic relaxation strategies reduce perceived stress and physiological markers of stress.... Read more »

  • November 17, 2014
  • 05:43 PM

Applications of homologous recombination-mediated genome engineering

by Jimann Shin in the Node

We recently demonstrated an improved method for homologous recombination (HR)-mediated genome editing using TALEN (Transcription activator-like effector nuclease) in zebrafish (Shin et al., 2014). In the study, we identified that a total of 3kb of homology in the targeting construct, 1kb of one arm and 2kb of the other arm, is sufficient to induce HR-mediated knock-in. […]... Read more »

  • November 17, 2014
  • 04:23 PM


by patricktschopp in the Node

The morphological evolution of limbs and external genitalia were both essential adaptions to a life on land. While the former deals with the novel locomotory challenges facing an animal invading a terrestrial environment, the latter is concerned with something even more essential: reproduction! Living on land means that gametes can no longer be fertilized externally […]... Read more »

Kondo T, Zákány J, Innis JW, & Duboule D. (1997) Of fingers, toes and penises. Nature, 390(6655), 29. PMID: 9363887  

Yamada, G., Suzuki, K., Haraguchi, R., Miyagawa, S., Satoh, Y., Kamimura, M., Nakagata, N., Kataoka, H., Kuroiwa, A., & Chen, Y. (2006) Molecular genetic cascades for external genitalia formation: An emerging organogenesis program. Developmental Dynamics, 235(7), 1738-1752. DOI: 10.1002/dvdy.20807  

Tschopp, P., Sherratt, E., Sanger, T., Groner, A., Aspiras, A., Hu, J., Pourquié, O., Gros, J., & Tabin, C. (2014) A relative shift in cloacal location repositions external genitalia in amniote evolution. Nature. DOI: 10.1038/nature13819  

Wagner, G. (2007) The developmental genetics of homology. Nature Reviews Genetics, 8(6), 473-479. DOI: 10.1038/nrg2099  

Shubin, N., Tabin, C., & Carroll, S. (2009) Deep homology and the origins of evolutionary novelty. Nature, 457(7231), 818-823. DOI: 10.1038/nature07891  

  • November 17, 2014
  • 03:33 PM

The (Re)discovery of a major brain pathway

by Gabriel in Lunatic Laboratories

It was like something out of a mystery movie, a couple of years ago a scientist, looking at dozens of MRI scans of human brains noticed something surprising. A large, fiber pathway that seemed to be part of the network of connections that process visual information showed up on the scans, but the researcher couldn’t find it mentioned in any of the modern-day anatomy textbooks he had.... Read more »

Brian Wandell, Jason Yeatman, & Kevin Weiner. (2014) The vertical occipital fasciculus: A century of controversy resolved by in vivo measurements. Proceedings of the National Academy of Sciences. info:/10.1073/pnas.1418503111

  • November 17, 2014
  • 11:54 AM

That’s a Higgs but how many?

by Marco Frasca in The Gauge Connection

CMS and ATLAS collaborations are yet up to work producing results from the datasets obtained in the first phase of activity of LHC. The restart is really near the corner and, maybe already the next summer, things can change considerably. Anyway what they get from the old data can be really promising and rather intriguing. […]... Read more »

Marco Frasca. (2013) Scalar field theory in the strong self-interaction limit. Eur. Phys. J. C (2014) 74:2929. arXiv: 1306.6530v5

Marco Frasca. (2012) Classical solutions of a massless Wess-Zumino model. J.Nonlin.Math.Phys. 20:4, 464-468 (2013). arXiv: 1212.1822v2

  • November 17, 2014
  • 10:55 AM

Eating Disorders in Obesity: DSM-IV and DSM-5

by William Yates, M.D. in Brain Posts

The recent revision of the American Psychiatric Associations Diagnostic and Statistical Manual for Mental Disorders, Fifth Edition (DSM-5) altered several eating disorder diagnostic criteria.Some have expressed concern that these revisions are overly broad and may result in over diagnosis in some clinical populations. One clinical population where this is a concern is obesity.A research study has been recently published addressing this issue.Jennifer Thomas and colleagues at Harvard University a........ Read more »

  • November 17, 2014
  • 09:15 AM

Habits and learning

by Janet Kwasniak in Neuro-patch

Habits allow us to perform actions without attending to every detail; we can do complex things and more than one action at a time without overloading our cognitive and motor systems. They are goal-directed macro actions made up of a sequence of simple primitive actions. A habit allows a complex action to be launched as […]... Read more »

Balderas, G. (2014) Habits as learning enhancers. Frontiers in Human Neuroscience. DOI: 10.3389/fnhum.2014.00918  

  • November 17, 2014
  • 07:08 AM

How guessing the wrong answer helps you learn the right answer

by BPS Research Digest in BPS Research Digest

Guessing, even wrongly, is thought toactivate webs of knowledge, which leadsto richer encoding of the correct answer. It's well known that taking tests helps us learn. The act of retrieving information from memory helps that information stick. This seems intuitive. More surprising is the recent discovery that guessing aids subsequent learning of the correct answer, even if your initial guess was wrong.Let's consider a simple example in the context of learning capital cities. Imagine you don........ Read more »

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