Translating Autism

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Translating Autism is an informational blog intended to rapidly disseminate the latest scientific findings related to the nature, causes, & treatments of autism spectrum disorders. Translating Autism reviews the latest scientific studies published in peer-reviewed journals and translate these findings into applicable and useful information for parents, teachers, clinicians.

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  • April 1, 2009
  • 10:35 AM
  • 1,256 views

Expressive communication in children with severe autism

by Nestor Lopez-Duran in Translating Autism

Harold L Doherty, an autism advocate and parent of a child with autism, has commented on the limited amount of research conducted with kids with severe autism. Although this is an empirical question, and I have not seen data confirming this possible trend, Mr. Doherty is most likely right, in that it appears that children with severe autism are underrepresented in today's published research. For

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  • March 31, 2009
  • 08:48 AM
  • 1,103 views

Eyes aversion reconsidered: Kids with autism may prefer Lip-Sync.

by Nestor Lopez-Duran in Translating Autism

Last week I discussed a study showing that kids with low functioning autism identify noses better when these are presented upside down than when presented upright. In the context of that study, the authors suggested that these kids have an aversion to examining eyes directly and tend to focus on parts of the face away from the eyes.This week a group of researchers from Yale University published a

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  • March 30, 2009
  • 11:49 AM
  • 979 views

Siblings of kids with autism: 7 years later.

by Nestor Lopez-Duran in Translating Autism

A number of studies have shown that some parents of children with autism show mild autistic tendencies. This has been called the 'broader autism phenotype'. However, less is known as to whether such phenomenon also affects typically developing brothers and sisters of children with autism. That is, are non-affected siblings of kids with autism free developmental problems or do they show a broader

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  • March 27, 2009
  • 09:33 AM
  • 867 views

Hyperbaric treatment for children with autism: First controlled clinical trials.

by Nestor Lopez-Duran in Translating Autism

This week Biomed central published a double-blind placebo study of the effectiveness of hyperbaric treatment for autism. The study was published in Biomed, which is an open access journal, so readers are invited to read the entire study here. In sum, the authors randomly assigned 62 children (52 boys, 10 girls) between the ages of 2 to 7 to either a hyperbaric treatment condition or a control... Read more »

Rossignol, D., Rossignol, L., Smith, S., Schneider, C., Logerquist, S., Usman, A., Neubrander, J., Madren, E., Hintz, G., Grushkin, B.... (2009) Hyperbaric treatment for children with autism: a multicenter, randomized, double-blind, controlled trial. BMC Pediatrics, 9(1), 21. DOI: 10.1186/1471-2431-9-21  

  • March 25, 2009
  • 09:01 AM
  • 1,093 views

Cognitive Behavioral Therapy for Anxiety in Autism

by Nestor Lopez-Duran in Translating Autism

A review of:Wood, J., Drahota, A., Sze, K., Har, K., Chiu, A., & Langer, D. (2009). Cognitive behavioral therapy for anxiety in children with autism spectrum disorders: a randomized, controlled trial Journal of Child Psychology and Psychiatry, 50 (3), 224-234 DOI: 10.1111/j.1469-7610.2008.01948.xThis is a randomized controlled study of the treatment of anxiety symptoms in children with high... Read more »

  • March 23, 2009
  • 10:08 AM
  • 843 views

Are Pressure Vests Effective? Why do we publish case reports?

by Nestor Lopez-Duran in Translating Autism

This week I will be writing a series of micro reviews of recent treatment studies. Some of these articles are controversial for different reasons, for example below I discuss issues with single-case reports and later this week I will discuss issues regarding conflict of interest in the publication process. The Journal of Autism and Developmental Disorders just published a case report on the... Read more »

  • March 20, 2009
  • 08:53 AM
  • 1,033 views

Eyes aversion in autism may affect face recognition

by Nestor Lopez-Duran in Translating Autism

A brief review of Annaz, D., Karmiloff-Smith, A., Johnson, M., & Thomas, M. (2009). A cross-syndrome study of the development of holistic face recognition in children with autism, Down syndrome, and Williams syndrome Journal of Experimental Child Psychology, 102 (4), 456-486 DOI: 10.1016/j.jecp.2008.11.005Holistic face recognition is the tendency to experience and process faces as a “whole”... Read more »

  • March 18, 2009
  • 09:28 AM
  • 964 views

How much does your pediatrician actually know about Autism?

by Nestor Lopez-Duran in Translating Autism

A review of: Golnik, A., Ireland, M., & Borowsky, I. (2009). Medical Homes for Children With Autism: A Physician Survey PEDIATRICS, 123 (3), 966-971 DOI: 10.1542/peds.2008-1321I’m usually extremely political when talking about other disciplines (pediatricians, speech therapists, neurologists, etc) since I think all of these clinicians have an important role in the care of children with autism.... Read more »

  • March 16, 2009
  • 09:00 AM
  • 1,106 views

Sensory sensitivity as early sign of autism: more empirical evidence.

by Nestor Lopez-Duran in Translating Autism

When compared to children with non-ASD developmental delays, children with autism had significantly more tactile sensitivity, auditory anomalies (low response), and taste/smell sensitivity. A brief review of: Wiggins, L., Robins, D., Bakeman, R., & Adamson, L. (2009). Breif Report: Sensory Abnormalities as Distinguishing Symptoms of Autism Spectrum Disorders in Young Children Journal of Autism... Read more »

  • March 13, 2009
  • 09:15 AM
  • 961 views

Autism, memory and theory of mind: Do parents of kids with autism show deficits?

by Nestor Lopez-Duran in Translating Autism

Some parents of children with low functioning autism show evidence of impaired social cognition and working memory.A brief review of: Sezen Gokcen, Emre Bora, Serpil Erermis, Hande Kesikci, Cahide Aydin (2009). Theory of mind and verbal working memory deficits in parents of autistic children Psychiatry Research, 166 (1), 46-53 DOI: 10.1016/j.psychres.2007.11.016I have written several times about... Read more »

Sezen Gokcen, Emre Bora, Serpil Erermis, Hande Kesikci, & Cahide Aydin. (2009) Theory of mind and verbal working memory deficits in parents of autistic children. Psychiatry Research, 166(1), 46-53. DOI: 10.1016/j.psychres.2007.11.016  

  • March 11, 2009
  • 09:44 AM
  • 1,125 views

Language and Autism: Grammaticality Judgments

by Nestor Lopez-Duran in Translating Autism

Children with autism show deficits in grammatical judgments but this may be due to working memory deficits.A brief review of: INGE-MARIE EIGSTI, LOISA BENNETTO (2009). Grammaticality judgments in autism: Deviance or delay Journal of Child Language DOI: 10.1017/s0305000909009362In this study the authors compared 21 children with ASDs (19 males, 10 to 16 years) and 22 typically developing kids (20... Read more »

INGE-MARIE EIGSTI, & LOISA BENNETTO. (2009) Grammaticality judgments in autism: Deviance or delay. Journal of Child Language, 1. DOI: 10.1017/s0305000909009362  

  • March 9, 2009
  • 09:38 AM
  • 925 views

Autism, neurofeedback , and the processing of novel distracters

by Nestor Lopez-Duran in Translating Autism

Children with autism show increased reaction time and unique brain wave patters during tasks that include novel distracters.A review of: Estate Sokhadze, Joshua Baruth, Allan Tasman, Lonnie Sears, Grace Mathai, Ayman El-Baz, Manuel F. Casanova (2009). Event-related Potential Study of Novelty Processing Abnormalities in Autism Applied Psychophysiology and Biofeedback, 34 (1), 37-51 DOI: 10.1007/... Read more »

Estate Sokhadze, Joshua Baruth, Allan Tasman, Lonnie Sears, Grace Mathai, Ayman El-Baz, & Manuel F. Casanova. (2009) Event-related Potential Study of Novelty Processing Abnormalities in Autism. Applied Psychophysiology and Biofeedback, 34(1), 37-51. DOI: 10.1007/s10484-009-9074-5  

  • March 6, 2009
  • 09:01 AM
  • 1,068 views

Vision problems in autism: Reduced convergence?

by Nestor Lopez-Duran in Translating Autism

Analysis of visual functioning in children with autism suggests impairment in visual convergence. A brief review of: Elizabeth Milne, Helen Griffiths, David Buckley, Alison Scope (2009). Vision in Children and Adolescents with Autistic Spectrum Disorder: Evidence for Reduced Convergence Journal of Autism and Developmental Disorders DOI: 10.1007/s10803-009-0705-8Although clinical observations,... Read more »

  • March 4, 2009
  • 09:24 AM
  • 1,033 views

Sevoflurane and Autism: Animal evidence of neonatal anesthesia risk?

by Nestor Lopez-Duran in Translating Autism

Animal study indicates that neonatal exposure to the anesthetic sevoflurane may lead to abnormal social behaviors.A review of: Maiko Satomoto, Yasushi Satoh, Katsuo Terui, Hideki Miyao, Kunio Takishima, Masataka Ito, Junko Imaki (2009). Neonatal Exposure to Sevoflurane Induces Abnormal Social Behaviors and Deficits in Fear Conditioning in Mice Anesthesiology, 110 (3), 628-637 DOI: 10.1097/ALN... Read more »

  • March 2, 2009
  • 08:59 AM
  • 989 views

Amygdala, autism and clinical impairment: When group comparisons are not enough.

by Nestor Lopez-Duran in Translating Autism

Two metabolites in the amygdala are associated with clinical impairment in autism. A review of: Natalia M. Kleinhans, Todd Richards, Kurt E. Weaver, Olivia Liang, Geraldine Dawson, Elizabeth Aylward (2009). Brief Report: Biochemical Correlates of Clinical Impairment in High Functioning Autism and Asperger’s Disorder Journal of Autism and Developmental Disorders DOI: 10.1007/s10803-009-0707-6This brief yet powerful article is an example of research moving beyond making simple comparisons betwee........ Read more »

Natalia M. Kleinhans, Todd Richards, Kurt E. Weaver, Olivia Liang, Geraldine Dawson, & Elizabeth Aylward. (2009) Brief Report: Biochemical Correlates of Clinical Impairment in High Functioning Autism and Asperger’s Disorder. Journal of Autism and Developmental Disorders. DOI: 10.1007/s10803-009-0707-6  

  • February 27, 2009
  • 05:30 PM
  • 833 views

Autism coverage and insurance premiums

by Nestor Lopez-Duran in Translating Autism

Autism insurance coverage at the rate of 20,000 per year would result in an insurance premium increase of $2.18 per month for the average family.A review/summary of: James N. Bouder, Stuart Spielman, David S. Mandell (2009). Brief Report: Quantifying the Impact of Autism Coverage on Private Insurance Premiums Journal of Autism and Developmental Disorders DOI: 10.1007/s10803-009-0701-zHealth care expenditures for children with autism and other ASD are disproportionally absorbed by families as com........ Read more »

  • February 25, 2009
  • 09:35 AM
  • 1,028 views

Autism and Serotonin: Is MAOB the missing link?

by Nestor Lopez-Duran in Translating Autism

A review of: Dubravka Hranilović, Zorana Bujas-Petković, Maja Tomičić, Tatjana Bordukalo-Nikšić, Sofia Blažević, Lipa Čičin-Šain (2009). Hyperserotonemia in autism: activity of 5HT-associated platelet proteins Journal of Neural Transmission DOI: 10.1007/s00702-009-0192-2Although dysregulation of serotonin has been associated with several psychiatric disorders, there is evidence suggesting that disruption in serotonin systems may be implicated in autism. Specifically, serotonin is a cr........ Read more »

Dubravka Hranilović, Zorana Bujas-Petković, Maja Tomičić, Tatjana Bordukalo-Nikšić, Sofia Blažević, & Lipa Čičin-Šain. (2009) Hyperserotonemia in autism: activity of 5HT-associated platelet proteins. Journal of Neural Transmission. DOI: 10.1007/s00702-009-0192-2  

  • February 20, 2009
  • 09:31 AM
  • 907 views

Oral immunoglobulin and Autism: Study shows no treatment effect.

by Nestor Lopez-Duran in Translating Autism

A review of: Benjamin L. Handen, Raun D. Melmed, Robin L. Hansen, Michael G. Aman, David L. Burnham, Jon B. Bruss, Christopher J. McDougle (2009). A Double-Blind, Placebo-Controlled Trial of Oral Human Immunoglobulin for Gastrointestinal Dysfunction in Children with Autistic Disorder Journal of Autism and Developmental Disorders DOI: 10.1007/s10803-008-0687-yI have previously reviewed studies testing the basic premises of the leaky gut theory of autism. This theory suggests that children with au........ Read more »

  • February 19, 2009
  • 10:30 AM
  • 962 views

High functioning autism vs. Asperger's. Autism diagnostic issues (Part II)

by Nestor Lopez-Duran in Translating Autism

Part II review of: Fred R. Volkmar, Matthew State, Ami Klin (2009). Autism and autism spectrum disorders: diagnostic issues for the coming decade Journal of Child Psychology and Psychiatry, 50 (1-2), 108-115 DOI: 10.1111/j.1469-7610.2008.02010.xMuch controversy and confusion remains about the differences between high functioning autism and Asperger’s syndrome. As the authors described, there are many areas of overlap as well as differences between the original Asperger’s proposal and autism......... Read more »

Fred R. Volkmar, Matthew State, & Ami Klin. (2009) Autism and autism spectrum disorders: diagnostic issues for the coming decade. Journal of Child Psychology and Psychiatry, 50(1-2), 108-115. DOI: 10.1111/j.1469-7610.2008.02010.x  

  • February 19, 2009
  • 10:30 AM
  • 873 views

High functioning autism vs. Asperger's. Autism diagnostic issues (Part II)

by Nestor Lopez-Duran in Translating Autism

Part II review of: Fred R. Volkmar, Matthew State, Ami Klin (2009). Autism and autism spectrum disorders: diagnostic issues for the coming decade Journal of Child Psychology and Psychiatry, 50 (1-2), 108-115 DOI: 10.1111/j.1469-7610.2008.02010.xMuch controversy and confusion remains about the differences between high functioning autism and Asperger’s syndrome. As the authors described, there are

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Fred R. Volkmar, Matthew State, & Ami Klin. (2009) Autism and autism spectrum disorders: diagnostic issues for the coming decade. Journal of Child Psychology and Psychiatry, 50(1-2), 108-115. DOI: 10.1111/j.1469-7610.2008.02010.x  

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