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Brief summaries of sick papes.
Sick Papes
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- January 22, 2013
- 03:54 PM
- 138 views
These dudes figured out how to identify supposedly anonymous people whose genomes are publically available
by Sick Papes in Sick Papes
Super nasty genome hacking I CANT BELIEVE IT!!... Read more »
Gymrek M, McGuire AL, Golan D, Halperin E, & Erlich Y. (2013) Identifying personal genomes by surname inference. Science (New York, N.Y.), 339(6117), 321-4. PMID: 23329047
- January 3, 2013
- 04:23 PM
- 103 views
A large-scale model of the functioning brain.
by Sick papes in Sick Papes
The H. P. Lovecraft novella At the Mountains of Madness is a story about scientific hubris, and the insignificance of human achievement when confronted with the vastness that is the cosmos...... Read more »
Eliasmith, C., Stewart, T., Choo, X., Bekolay, T., DeWolf, T., Tang, Y., & Rasmussen, D. (2012) A Large-Scale Model of the Functioning Brain. Science, 338(6111), 1202-1205. DOI: 10.1126/science.1225266
- December 19, 2012
- 06:57 PM
- 225 views
God made Eve from Adam's Penis Bone
by Sick Papes in Sick Papes
Gilbert, S., & Zevit, Z. (2001). Congenital human baculum deficiency: The generative bone of Genesis 2:21-23 American Journal of Medical Genetics, 101 (3), 284-285 DOI: 10.1002/ajmg.1387
Humans are the only primates that don’t have bones in their penises (dicks). This beautiful pape proves that this is because God took the penis bone out of Adam to make Eve.
Though hilarious, this pape is actually a work of legit biblical scholarship by my scientific hero, Dr. Scott Gilbert, who literally ........ Read more »
Gilbert, S., & Zevit, Z. (2001) Congenital human baculum deficiency: The generative bone of Genesis 2:21-23. American Journal of Medical Genetics, 101(3), 284-285. DOI: 10.1002/ajmg.1387
- December 18, 2012
- 07:11 PM
- 163 views
Giant Robber Crabs Monitored from Space
by Sick Papes in Sick Papes
Krieger J, Grandy R, Drew MM, Erland S, Stensmyr MC, Harzsch S, & Hansson BS (2012). Giant Robber Crabs Monitored from Space: GPS-Based Telemetric Studies on Christmas Island (Indian Ocean). PloS one, 7 (11) PMID: 23166774
Anybody who knows me will tell you that I have a soft spot in my heart for the hard shell of our fellow crab-man. For all the land-lubbers out there, the crab is a heavily-armored, sideways-running little fellow that specializes in shoveling detritus (= trash) into its adorab........ Read more »
Krieger J, Grandy R, Drew MM, Erland S, Stensmyr MC, Harzsch S, & Hansson BS. (2012) Giant Robber Crabs Monitored from Space: GPS-Based Telemetric Studies on Christmas Island (Indian Ocean). PloS one, 7(11). PMID: 23166774
- December 8, 2012
- 04:40 PM
- 105 views
Spider legs and credit card debt
by Sick Papes in Sick Papes
Although I cannot mask my disappointment that it has taken 2012 years, I am nonetheless ecstatic to report that humankind has collectively figured out how to make four-legged and ten-legged spiders.... Read more »
Schwager, E., Pechmann, M., Feitosa, N., McGregor, A., & Damen, W. (2009) hunchback Functions as a Segmentation Gene in the Spider Achaearanea tepidariorum. Current Biology, 19(16), 1333-1340. DOI: 10.1016/j.cub.2009.06.061
- December 4, 2012
- 01:45 PM
- 172 views
Druckmann, S., & Chklovskii, D. (2012). Neuronal Circuits...
by Sick Papes in Sick Papes
To celebrate the dawn of December, a month of intense introspection and widespread brooding, Sick Papes brings you an exclusive soul-wrenching interview with neuroscientist and celebrity theoretician, Dr. Shaul Druckmann. Shaul’s recent pape (w/ Mitya Chklovskii) suggests a fresh answer to a beguiling question- how does the brain maintain persistent representations despite the fact that neuronal activity is constantly changing?
Personal experience tells us that the brain can maintain stable r........ Read more »
Druckmann, S., & Chklovskii, D. (2012) Neuronal Circuits Underlying Persistent Representations Despite Time Varying Activity. Current Biology, 22(22), 2095-2103. DOI: 10.1016/j.cub.2012.08.058
- November 25, 2012
- 07:28 PM
- 127 views
Mainen, Z., & Sejnowski, T. (1995). Reliability of spike...
by Sick Papes in Sick Papes
It is with great ambivalence that we recently learned that Hostess Bakeries, the corporation that coated generations of sniveling youngsters with a thin sticky film of fructose, has permanently extinguished its great roaring Twinkie ovens. Since the Great Depression, the specter of Hostess has haunted the American childhood, transforming many precocious naturalists-to-be into taffy-gargling, scrap-booking diabetic uncles. My own personal savior from the purgatory of Ding-Dong-dom was the health-........ Read more »
Mainen, Z., & Sejnowski, T. (1995) Reliability of spike timing in neocortical neurons. Science, 268(5216), 1503-1506. DOI: 10.1126/science.7770778
- October 30, 2012
- 08:47 PM
- 68 views
The cells that regulate sex hormones are born in your nose
by Sick Papes in Sick Papes
First things first: I just want to be totally clear that there is nothing funny about sickness, as it is traditionally defined. Real diseases aren’t a joke, no two ways about that.
But diseases can also reveal some of the really surprising ways that our bodies work. For instance, as many of my distinguished (and currently robo-tripping in the parking lot of a Houston Astro’s game) colleagues have pointed out, we know a lot about how language works from studies of people who have outrageousl........ Read more »
Hanchate NK, Giacobini P, Lhuillier P, Parkash J, Espy C, Fouveaut C, Leroy C, Baron S, Campagne C, Vanacker C.... (2012) SEMA3A, a gene involved in axonal pathfinding, is mutated in patients with Kallmann syndrome. PLoS genetics, 8(8). PMID: 22927827
- September 20, 2012
- 08:24 AM
- 106 views
Sick Papes Special on Central Pattern Generators, Part 2Finan...
by Sick Papes in Sick Papes
There is a rumor in the scientific community that, by entering the right combination of keywords and Boolean expressions into PubMed, one can unlock a clandestine trove of high-quality, peer-reviewed, NIH-funded pornography. Although the cipher has not yet been cracked (it’s definitely not “intrinsic+sucking+dynamics-nutritive”), this exercise recently led us to a fetching little pape of disarming sickness.
In 1998, Donald Finan and Steven Barlow embarked on the exploration of the central........ Read more »
Finan DS, & Barlow SM. (1998) Intrinsic dynamics and mechanosensory modulation of non-nutritive sucking in human infants. Early human development, 52(2), 181-97. PMID: 9783819
- September 17, 2012
- 09:42 PM
- 75 views
Sick Papes Special on Central Pattern Generators, Part 1
by Sick Papes in Sick Papes
It’s such a personal fantasy to go from human domestication into genetics into neural circuit physiology.... Read more »
Andersson, L., Larhammar, M., Memic, F., Wootz, H., Schwochow, D., Rubin, C., Patra, K., Arnason, T., Wellbring, L., Hjälm, G.... (2012) Mutations in DMRT3 affect locomotion in horses and spinal circuit function in mice. Nature, 488(7413), 642-646. DOI: 10.1038/nature11399
- August 2, 2012
- 07:28 PM
- 97 views
Warmth, flight, and hallucinogenic beauty: the story of feather evolution
by Sick Papes in Sick Papes
Bear with me as I share with you a tale of woe. Last summer, I had just taken a bunch of unusually strong hallucinogenic mushrooms when I learned via text-message that my family dog had been killed by coyotes. This obviously would have been devastating news under any circumstances, but given my precarious situation I had to additionally deal with the threat of having a dangerously terrible psychedelic experience. As I teetered on the edge, I received another text message - this one from a dear f........ Read more »
Ng CS, Wu P, Foley J, Foley A, McDonald ML, Juan WT, Huang CJ, Lai YT, Lo WS, Chen CF.... (2012) The chicken frizzle feather is due to an α-keratin (KRT75) mutation that causes a defective rachis. PLoS genetics, 8(7). PMID: 22829773
- July 18, 2012
- 09:20 PM
- 97 views
Brennecke, J. et al. An epigenetic role for maternally inherited...
by Sick Papes in Sick Papes
In his classic song “Heart of a Woman” (Double Up; 2007, Jive/Zumba Records), R. Kelly lays out the list of qualities of women which make them so wonderful:
1) “[Women] take us and lift us up.”
2) “[Women] give us chance after chance and we still find a way to F things up.”
3) “[Women] love us so much our lies become the truth.”
4) “[Women find] a way to smile just to keep from showing [their] hurt.”
I know what you’re thinking: this is definitely a comprehensive list ........ Read more »
Vagin VV, Sigova A, Li C, Seitz H, Gvozdev V, & Zamore PD. (2006) A distinct small RNA pathway silences selfish genetic elements in the germline. Science (New York, N.Y.), 313(5785), 320-4. PMID: 16809489
- June 6, 2012
- 03:26 PM
- 100 views
Jonathan D. Charlesworth„ Timothy L. Warren, & Michael...
by Sick Papes in Sick Papes
This hump day, we at Sick Papes bring you an exclusive heart-to-heart poolside chat with Jonathan Charlesworth, the author of a hot-off-the-press pape that was described by one of our Sick Papes interns as, “so-sick-it’ll-make-your-antiobiotic-resistant-staph-infection-feel-like-a-sensuous-spaghetti-squash-rubdown.” Currently AOP in the journal Nature, Jonathan’s pape investigates the neural mechanisms of trial-and-error song learning in the adorable Bengalese Finch. Along with his emin........ Read more »
Jonathan D. Charlesworth,, Timothy L. Warren, & Michael S. Brainard. (2012) Covert skill learning in a cortical-basal ganglia circuit. Nature. DOI: 10.1038/nature11078
- May 23, 2012
- 05:52 PM
- 103 views
Kato M, Han TW, Xie S, Shi K, Du X, Wu LC, Mirzaei H, Goldsmith...
by Sick Papes in Sick Papes
Strap in, friends, because I’m about to tell you about the weirdest pape I have ever read [editor’s note: it’s also fucking SICK]. To help prepare for the emotional landscape that you will traverse as you read it, I suggest starting with the following sentence, which comes at the end of the acknowledgements section: “This work was funded by an unrestricted endowment provided S.L.M [the senior author] by an anonymous donor.”
Out of curiosity, reader, what would you do if a masked stran........ Read more »
Kato M, Han TW, Xie S, Shi K, Du X, Wu LC, Mirzaei H, Goldsmith EJ, Longgood J, Pei J.... (2012) Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels. Cell, 149(4), 753-67. PMID: 22579281
- February 8, 2012
- 08:01 AM
- 123 views
Dank De Novo: The Purple Kush Genome
by Sick Papes in Sick Papes
The weed genome... Read more »
van Bakel, H., Stout, J., Cote, A., Tallon, C., Sharpe, A., Hughes, T., & Page, J. (2011) The draft genome and transcriptome of Cannabis sativa. Genome Biology, 12(10). DOI: 10.1186/gb-2011-12-10-r102
- November 30, 1999
- 12:00 AM
- 43 views
Tadpoles see through their asses
by Papes in Sick Papes
A compelling example of the brain’s dynamic ballsiness (i.e., the ability of neural circuits to learn to detect unfamiliar sensory stimuli), is described in a recent exercise in sickness by the duo of Blackiston and Levin. ... Read more »
Blackiston DJ, & Levin M. (2013) Ectopic eyes outside the head in Xenopus tadpoles provide sensory data for light-mediated learning. The Journal of experimental biology, 216(Pt 6), 1031-40. PMID: 23447666
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