Science-Based Medicine

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Exploring issues and controversies in the relationship between science and medicine

Peter Lipson
13 posts

5 posts

Scott Gavura
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  • November 17, 2008
  • 04:03 AM

On the dangers of using valid placebo controls in clinical trials of acupuncture

by David Gorski in Science-Based Medicine

I don’t recall if I’ve ever mentioned this before on this blog, but there was a time when I was less skeptical of acupuncture than I am now. It’s true. Don’t get me wrong, though. I never for a minute considered that the whole rigamarole about “unblocking” or “redirecting” the flow of that mystical life [...]... Read more »

  • October 27, 2008
  • 05:00 AM

Placebos in the news again

by David Gorski in Science-Based Medicine

Towards the end of last week, I was contemplating what I would be writing about for Monday. No topic had quite floated my boat, but I hated to dip into the archive of topics I’ve written about before to update a post. After all, I like to be topical whenever possible. Then what to my [...]... Read more »

  • October 14, 2008
  • 05:00 AM

Massage for AIDS

by SBMBlogger in Science-Based Medicine

I recently learned of a study entitled “Dominican Children with HIV not Receiving Antiretrovirals: Massage Therapy Influences their Behavior and Development.” It disturbed me, and I couldn’t get it out of my head. They’re massaging these kids but letting them die of AIDS? I went back and read the complete article, and it left me [...]... Read more »

M. Hernandez-Reif, G. Shor-Posner, J. Baez, S. Soto, R. Mendoza, R. Castillo, N. Quintero, E. Perez, & G. Zhang. (2006) Dominican Children with HIV not Receiving Antiretrovirals: Massage Therapy Influences their Behavior and Development. Evidence-based Complementary and Alternative Medicine, 5(3), 345-354. DOI: 10.1093/ecam/nem032  

  • October 13, 2008
  • 02:01 AM

Fun with homeopaths and meta-analyses of homeopathy trials

by SBMBlogger in Science-Based Medicine

Homeopathy amuses me.

Well, actually it both amuses me and appalls me. The amusement comes from just how utterly ridiculous the concepts between homeopathy are. Think about it. It is nothing but pure magical thinking. Indeed, at the very core of homeopathy is a concept that can only be considered to be magic. In homeopathy, the [...]... Read more »

  • September 23, 2008
  • 09:00 AM

FDA approval of drugs and transparency in clinical trial results

by SBMBlogger in Science-Based Medicine

Note: The reason that I am posting today rather than my usual Monday slot is because the article I discuss here was embargoed until last night. Consequently, I asked Harriet if she would trade days with me this week, and she was kind enough to do so.

One thing that science relies on almost absolutely is [...]... Read more »

  • August 25, 2008
  • 10:00 AM

Threats to science-based medicine: When clinical trials for new drugs are designed by the marketing division

by SBMBlogger in Science-Based Medicine

When the marketing division designs clinical trials, scientific medicine loses.... Read more »

Kevin Hill, Joseph S. Ross, David S. Egilman, & Harlan M. Krumholz. (2008) The ADVANTAGE Seeding Trial: A Review of Internal Documents. Annals of Internal Medicine, 149(4), 251-258.

Harold Sox, & Drummond Rennie. (2008) Seeding Trials: Just Say \"No\". Annals of Internal Medicine, 149(4), 279-280.

  • August 18, 2008
  • 10:00 AM

High dose vitamin C and cancer: Has Linus Pauling been vindicated?

by SBMBlogger in Science-Based Medicine


Vitamin C as a treatment for cancer is back in the news again.

I’m not surprised. This is one therapy favored by advocates of “alternative” medicine that keeps popping up periodically (seemingly every couple of years or so). This latest bit of news has turned up almost right on time after the last [...]... Read more »

L Hoffer, M Levine, S Assouline, D Melnychuk, S J Padayatty, K Rosadiuk, C Rousseau, L Robitaille, & W H Miller. (2008) Phase I clinical trial of i.v. ascorbic acid in advanced malignancy. Annals of Oncology. DOI: 10.1093/annonc/mdn377  

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