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A look at advances and highlights in the world of microbiology.
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Tim Sampson
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- March 22, 2008
- 09:07 PM
- 1,082 views
I'll Have My Bacteria Extra-CRISPR
by Tim Sampson in The Times Microbial
The microbial cold war between species has been widely studied and is, in my opinion, one of the most interesting topics in current biology. Fungi make compounds to destroy bacteria, bacteria make compounds to destroy fungi. But it doesn't stop there. Phages mutate constantly to evade bacterial defenses. We've known about a handful of bacterial defenses against phage-- repressor systems, restriction enzymes, receptor modification, DNA modification, etc. We have utlized these ........ Read more »
Rotem Sorek, Victor Kunin, & Philip Hugenholtz. (2008) CRISPR — a widespread system that provides acquired resistance against phages in bacteria and archaea. Nature Reviews Microbiology, 6(3), 181-186. DOI: 10.1038/nrmicro1793
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