4 posts · 7,901 views
a blog about eyes, fishes, undergraduate research and teaching
Understanding how blood cells are formed is not only important for developing treatments against numerous diseases, but also teaches us more about the fascinating process of turning stem cells into their specialized descendants. Recent work suggests that the initial stem cell that produces all of our blood’s formed elements (cells) comes in two flavors. But [...]... Read more »
Bertrand, J., Chi, N., Santoso, B., Teng, S., Stainier, D., & Traver, D. (2010) Haematopoietic stem cells derive directly from aortic endothelium during development. Nature, 464(7285), 108-111. DOI: 10.1038/nature08738
Kissa, K., & Herbomel, P. (2010) Blood stem cells emerge from aortic endothelium by a novel type of cell transition. Nature, 464(7285), 112-115. DOI: 10.1038/nature08761
I love showing students new research that will ultimately lead to a revision in their textbooks. Hey, something has got to make purchasing a new edition every two to three years seem worthwhile. And it is even more fun when these research headlines come out as we are covering that very topic in class. A [...]... Read more »
Challen, G., Boles, N., Chambers, S., & Goodell, M. (2010) Distinct Hematopoietic Stem Cell Subtypes Are Differentially Regulated by TGF-β1. Cell Stem Cell, 6(3), 265-278. DOI: 10.1016/j.stem.2010.02.002
When teaching marine biology I warn my students that if they are there to just learn about sharks and dolphins they will be sorely disappointed, because only microscopic plankton have the biomass to really affect the oceans. Being an ichthyologist this always hurt a bit. A recent paper in Science has restored my faith that all [...]... Read more »
R. W. Wilson, F. J. Millero, J. R. Taylor, P. J. Walsh, V. Christensen, S. Jennings, & M. Grosell. (2009) Contribution of Fish to the Marine Inorganic Carbon Cycle. Science, 323(5912), 359-362. DOI: 10.1126/science.1157972
Changing climates have the potential to wreck havoc on living things, which are often adapted to very specific local temperatures. These changes can alter the structure and, therefore, the function of the tens of thousands of proteins that keep cells and their owners alive. Yet, the presence of living things in extreme environments ranging from [...]... Read more »
Y. Dong, & G. N. Somero. (2009) Temperature adaptation of cytosolic malate dehydrogenases of limpets (genus Lottia): differences in stability and function due to minor changes in sequence correlate with biogeographic and vertical distributions. Journal of Experimental Biology, 212(2), 169-177. DOI: 10.1242/jeb.024505
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