295 posts · 212,659 views
Phased presents science journalism written for a lay audience, intending to cover technical subjects in an accessible manner. It covers science directly from the technical literature, and a wide range of subject areas.
Anindita Das, Rakesh Kukreja (Virginia Commonwealth University, United States) and coworkers have shown that Viagra enhances the efficacy of doxorubicin against prostate cancer, minimizes the damage done to healthy cells, and reduces the heart damage caused by doxorubicin, findings very likely to find their way into real-world clinical settings in the short-term. This news feature was written on October 1, 2010.... Read more »
Das, A., Durrant, D., Mitchell, C., Mayton, E., Hoke, N. N., Salloum, F. N., Park, M. A., Qureshi, I., Lee, R., Dent, P.... (2010) Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1006965107
Ali Dhinojwala (University of Akron, United States) and coworkers have found that the adhesive of orb-weaving spider webs is a viscoelastic solid, with implications in how the webs effectively ensnare quickly-moving prey as well as the design of synthetic adhesives. This news feature was written on September 29, 2010.... Read more »
Dwayne Miller (University of Toronto, Canada) and coworkers have developed a picosecond infrared laser scalpel that reduces the scarring and adjacent tissue damage seen after conventional surgical incisions. This news feature was written on September 28, 2010.... Read more »
Amini-Nik, S., Kraemer, D., Cowan, M. L., Gunaratne, K., Nadesan, P., Alman, B. A., & Miller, R. J. D. (2010) Ultrafast Mid-IR Laser Scalpel: Protein Signals of the Fundamental Limits to Minimally Invasive Surgery. PLoS ONE, 5(9). DOI: 10.1371/journal.pone.0013053
Molly Crockett (University of Cambridge, United Kingdom) and coworkers present evidence that supports the harm aversion hypothesis, rather than the emotional regulation hypothesis, of serotonin's modulation of prosocial behavior. This news feature was written on September 28, 2010.... Read more »
Crockett, M. J., Clark, L., Hauser, M. D., & Robbins, T. W. (2010) Serotonin selectively influences moral judgment and behavior through effects on harm aversion. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1009396107
The research of Philipp Holliger (Medical Research Council, United Kingdom) and coworkers suggests that ice may have helped the first RNA molecules to self-replicate and isolate themselves from the surrounding environment, thereby serving as the first primitive living "cell." This news feature was written on September 27, 2010.... Read more »
David Rueda (Wayne State University, United States) and coworkers have quantitated kinetic barriers to refolding in DNA and RNA, uncovering rare and transient events only addressable on the single molecule level. This news feature was written on September 25, 2010.... Read more »
Erik Meijaard (People and Nature Consulting International, and Australian National University) and coworkers have asked whether paper plantations can provide valuable habitat for orangutan conservation. This news feature was written on September 23, 2010.... Read more »
Meijaard, E., Albar, G., Nardiyono,, Rayadin, Y., Ancrenaz, M., & Spehar, S. (2010) Unexpected Ecological Resilience in Bornean Orangutans and Implications for Pulp and Paper Plantation Management. PLoS ONE, 5(9). DOI: 10.1371/journal.pone.0012813
Igor Sokolov (Clarkson University, United States) and coworkers have used atomic force microscopy to probe ladybug response and adaptability to flashing lights, and have unexpectedly found that ladybugs are blind to emerald light. This news feature was written on September 22, 2010.... Read more »
Guz, N. V., Dokukin, M. E., & Sokolov, I. (2010) Atomic Force Microscopy Study of Nano-Physiological Response of Ladybird Beetles to Photostimuli. PLoS ONE, 5(9). DOI: 10.1371/journal.pone.0012834
Erin Hanson and Jack Ballantyne (National Center for Forensic Science and University of Central Florida, United States) have determined the age of bloodstains via hemoglobin oxidation chemistry and cheap, portable instrumentation. This news feature was written on September 21, 2010.... Read more »
Hanson, E. K., & Ballantyne, J. (2010) A Blue Spectral Shift of the Hemoglobin Soret Band Correlates with the Age (Time Since Deposition) of Dried Bloodstains. PLoS ONE, 5(9). DOI: 10.1371/journal.pone.0012830
Nicole Zitzmann (University of Oxford, United Kingdom) and coworkers' research shows exceptional promise for dramatically improving treatment efficacy for hepatitis B, hepatitis C, and HIV. This news feature was written on September 20, 2010.... Read more »
Pollock, S.;, Nichita, N. B.;, Böhmera, A.;, Radulescu. C.;, Dwek, R. A.;, & Zitzmann, N. (2010) Polyunsaturated liposomes are antiviral against hepatitis B and C viruses and HIV by decreasing cholesterol levels in infected cells. Proceedings of the National Academy of Sciences. info:/10.1073/pnas.1009445107
Daniel Goldman (Georgia Institute of Technology, United States) and coworkers' research will be useful for Loggerhead sea turtle conservation, as well as the design of robots that can walk across challenging surfaces. This news feature was written on September 20, 2010.... Read more »
Mazouchova, N., Gravish, N., Savu, A., & Goldman, D. I. (2010) Utilization of granular solidification during terrestrial locomotion of hatchling sea turtles. Biology Letters, 6(3), 398-401. DOI: 10.1098/rsbl.2009.1041
Ingi Agnarsson (University of Puerto Rico, Slovenian Academy of Sciences and Arts, and University of Akron) and coworkers' discovery will aid efforts aimed at synthesizing super tough and stretchy synthetic fibers. This news feature was written on September 18, 2010.... Read more »
Agnarsson, I., Kuntner, M., & Blackledge, T. A. (2010) Bioprospecting Finds the Toughest Biological Material: Extraordinary Silk from a Giant Riverine Orb Spider. PLoS ONE, 5(9). DOI: 10.1371/journal.pone.0011234
Maya Elbaz and Sigal Ben-Yehuda (Hebrew University of Jerusalem) have found a functional linkage between cell shape and genetic replication in Bacillus subtilis cells, with possible implications in drug discovery. This news feature was written on September 17, 2010.... Read more »
Elbaz, M., & Ben-Yehuda, S. (2010) The Metabolic Enzyme ManA Reveals a Link between Cell Wall Integrity and Chromosome Morphology. PLoS Genetics, 6(9). DOI: 10.1371/journal.pgen.1001119
Jung-Hyun Lee, Sung Gyun Kang (Korean Ocean Research and Development Institute, and University of Science and Technology, Korea) and coworkers have found a microorganism which grows at 80 degrees Celsius, and uses formate to synthesize both hydrogen and adenosine triphosphate (energy) molecules, in oxygen-deprived conditions. This news feature was written on September 17, 2010.... Read more »
Harold Garner (Virginia Bioinformatics Institute, United States) and coworkers have improved upon the eTBLAST tool for uncovering plagiarism in the technical science literature. This news feature was written on September 16, 2010.... Read more »
Sun, Z., Errami, M., Long, T., Renard, C., Choradia, N., & Garner, H. (2010) Systematic Characterizations of Text Similarity in Full Text Biomedical Publications. PLoS ONE, 5(9). DOI: 10.1371/journal.pone.0012704
David Henry (Institute for Clinical Evaluative Sciences, Canada) and coworkers demonstrate that specialist health reporters deliver superior medical news reporting, with implications for news outlets facing financial pressure and competition from alternative media. This news feature was written on September 15, 2010.... Read more »
Paul Bates (University of Pennsylvania, United States) and coworkers have shown that Ebola-infected cells express a glycoprotein on the cell surface that shields the cells from the cell-mediated immune system, a finding which is also relevant to HIV and certain cancers. This news feature was written on September 14, 2010.... Read more »
Francica, J. R., Varela-Rohena, A., Medvec, A., Plesa, G., Riley, J. L., & Bates, P. (2010) Steric Shielding of Surface Epitopes and Impaired Immune Recognition Induced by the Ebola Virus Glycoprotein. PLoS Pathogens, 6(9). DOI: 10.1371/journal.ppat.1001098
Adriane Fugh-Berman (Georgetown University, United States) exposes the campaign of Wyeth and DesignWrite to falsely market hormone replacement therapy in non-symptomatic women, thereby profiting from a medical treatment which is not based on science. This news feature was written on September 13, 2010.... Read more »
Fugh-Berman, A. J. (2010) The Haunting of Medical Journals: How Ghostwriting Sold “HRT”. PLoS Medicine, 7(9). DOI: 10.1371/journal.pmed.1000335
Nir Goldman (Lawrence Livermore National Laboratory, United States) and coworkers' computer simulations suggest that the high temperatures and pressures of cometary impacts are sometimes within a range compatible with comets as a catalyst for amino acid synthesis in pre-life Earth. This news feature was written on September 12, 2010.... Read more »
Goldman, N., Reed, E. J., Fried, L. E., William Kuo, I.-F., & Maiti, A. (2010) Synthesis of glycine-containing complexes in impacts of comets on early Earth. Nature Chemistry. DOI: 10.1038/nchem.827
David Goldstein (Duke University, United States) and coworkers report steps towards unraveling the extent of human genetic variation, useful for directing medical effort towards genes critical to life. This news feature was written on September 12, 2010.... Read more »
Pelak, K., Shianna, K. V., Ge, D., Maia, J. M., Zhu, M., Smith, J. P., Cirulli, E. T., Fellay, J., Dickson, S. P., Gumbs, C. E.... (2010) The Characterization of Twenty Sequenced Human Genomes. PLoS Genetics, 6(9). DOI: 10.1371/journal.pgen.1001111
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