Phased

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295 posts · 184,430 views

Phased presents science journalism written for a lay audience, intending to cover technical subjects in an accessible manner. It covers science directly from the technical literature, and a wide range of subject areas.

Michael Long
295 posts

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  • October 1, 2010
  • 04:28 PM
  • 490 views

Viagra: A Chemotherapy Adjunct

by Michael Long in Phased

Anindita Das, Rakesh Kukreja (Virginia Commonwealth University, United States) and coworkers have shown that Viagra enhances the efficacy of doxorubicin against prostate cancer, minimizes the damage done to healthy cells, and reduces the heart damage caused by doxorubicin, findings very likely to find their way into real-world clinical settings in the short-term. This news feature was written on October 1, 2010.... Read more »

Das, A., Durrant, D., Mitchell, C., Mayton, E., Hoke, N. N., Salloum, F. N., Park, M. A., Qureshi, I., Lee, R., Dent, P.... (2010) Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1006965107  

  • September 29, 2010
  • 03:00 PM
  • 648 views

How Do Orb-Weaving Spider Webs Effectively Capture Fast-Moving Prey?

by Michael Long in Phased

Ali Dhinojwala (University of Akron, United States) and coworkers have found that the adhesive of orb-weaving spider webs is a viscoelastic solid, with implications in how the webs effectively ensnare quickly-moving prey as well as the design of synthetic adhesives. This news feature was written on September 29, 2010.... Read more »

Sahni, V., Blackledge, T. A., & Dhinojwala, A. (2010) Viscoelastic solids explain spider web stickiness. Nature Communications, 1(2), 1-4. DOI: 10.1038/ncomms1019  

  • September 28, 2010
  • 05:30 PM
  • 358 views

Minimally-Invasive Laser Surgery

by Michael Long in Phased

Dwayne Miller (University of Toronto, Canada) and coworkers have developed a picosecond infrared laser scalpel that reduces the scarring and adjacent tissue damage seen after conventional surgical incisions. This news feature was written on September 28, 2010.... Read more »

  • September 28, 2010
  • 03:30 PM
  • 621 views

Serotonin Modulates Prosocial Behavior via Harm Aversion

by Michael Long in Phased

Molly Crockett (University of Cambridge, United Kingdom) and coworkers present evidence that supports the harm aversion hypothesis, rather than the emotional regulation hypothesis, of serotonin's modulation of prosocial behavior. This news feature was written on September 28, 2010.... Read more »

  • September 27, 2010
  • 04:10 PM
  • 616 views

Was Ice the Original "Cell" in Early Earth?

by Michael Long in Phased

The research of Philipp Holliger (Medical Research Council, United Kingdom) and coworkers suggests that ice may have helped the first RNA molecules to self-replicate and isolate themselves from the surrounding environment, thereby serving as the first primitive living "cell." This news feature was written on September 27, 2010.... Read more »

Attwater, J., Wochner, A., Pinheiro, V. B., Coulson, A., & Holliger, P. (2010) Ice as a protocellular medium for RNA replication. Nature Communications, 1(6), 1-8. DOI: 10.1038/ncomms1076  

  • September 25, 2010
  • 01:25 PM
  • 805 views

Kinetic Traps of Single Biomolecule Refolding

by Michael Long in Phased

David Rueda (Wayne State University, United States) and coworkers have quantitated kinetic barriers to refolding in DNA and RNA, uncovering rare and transient events only addressable on the single molecule level. This news feature was written on September 25, 2010.... Read more »

Zhao, R., Marshall, M., Alemán, E. A., Lamichhane, R., Feig, A., & Rueda, D. (2010) Laser-Assisted Single-Molecule Refolding (LASR). Biophysical Journal, 99(6), 1925-1931. DOI: 10.1016/j.bpj.2010.07.019  

  • September 23, 2010
  • 11:35 AM
  • 347 views

Can Orangutans Survive in Paper Plantations?

by Michael Long in Phased

Erik Meijaard (People and Nature Consulting International, and Australian National University) and coworkers have asked whether paper plantations can provide valuable habitat for orangutan conservation. This news feature was written on September 23, 2010.... Read more »

  • September 22, 2010
  • 09:20 PM
  • 520 views

Ladybug Nanophysiological Response to Flashing Light

by Michael Long in Phased

Igor Sokolov (Clarkson University, United States) and coworkers have used atomic force microscopy to probe ladybug response and adaptability to flashing lights, and have unexpectedly found that ladybugs are blind to emerald light. This news feature was written on September 22, 2010.... Read more »

  • September 21, 2010
  • 12:58 PM
  • 629 views

Towards Practical Determination of Bloodstain Age

by Michael Long in Phased

Erin Hanson and Jack Ballantyne (National Center for Forensic Science and University of Central Florida, United States) have determined the age of bloodstains via hemoglobin oxidation chemistry and cheap, portable instrumentation. This news feature was written on September 21, 2010.... Read more »

  • September 20, 2010
  • 09:10 PM
  • 422 views

An Antiviral Agent that Acts by Targeting Cholesterol Biosynthesis

by Michael Long in Phased

Nicole Zitzmann (University of Oxford, United Kingdom) and coworkers' research shows exceptional promise for dramatically improving treatment efficacy for hepatitis B, hepatitis C, and HIV. This news feature was written on September 20, 2010.... Read more »

Pollock, S.;, Nichita, N. B.;, Böhmera, A.;, Radulescu. C.;, Dwek, R. A.;, & Zitzmann, N. (2010) Polyunsaturated liposomes are antiviral against hepatitis B and C viruses and HIV by decreasing cholesterol levels in infected cells. Proceedings of the National Academy of Sciences. info:/10.1073/pnas.1009445107

  • September 20, 2010
  • 05:00 PM
  • 456 views

Newborn Loggerhead Sea Turtles Exploit Surface Yield Stress to Walk Across Sand

by Michael Long in Phased

Daniel Goldman (Georgia Institute of Technology, United States) and coworkers' research will be useful for Loggerhead sea turtle conservation, as well as the design of robots that can walk across challenging surfaces. This news feature was written on September 20, 2010.... Read more »

  • September 18, 2010
  • 02:27 PM
  • 480 views

A Remarkably Tough and Stretchy Spider Silk

by Michael Long in Phased

Ingi Agnarsson (University of Puerto Rico, Slovenian Academy of Sciences and Arts, and University of Akron) and coworkers' discovery will aid efforts aimed at synthesizing super tough and stretchy synthetic fibers. This news feature was written on September 18, 2010.... Read more »

  • September 17, 2010
  • 06:35 PM
  • 423 views

Towards New Pharmaceuticals via Cell Wall Disruption

by Michael Long in Phased

Maya Elbaz and Sigal Ben-Yehuda (Hebrew University of Jerusalem) have found a functional linkage between cell shape and genetic replication in Bacillus subtilis cells, with possible implications in drug discovery. This news feature was written on September 17, 2010.... Read more »

  • September 17, 2010
  • 02:30 PM
  • 600 views

Oxygen-Deprived Microbial Growth on Formate: A Renewable Energy Source?

by Michael Long in Phased

Jung-Hyun Lee, Sung Gyun Kang (Korean Ocean Research and Development Institute, and University of Science and Technology, Korea) and coworkers have found a microorganism which grows at 80 degrees Celsius, and uses formate to synthesize both hydrogen and adenosine triphosphate (energy) molecules, in oxygen-deprived conditions. This news feature was written on September 17, 2010.... Read more »

Kim, Y. J., Lee, H. S., Kim, E. S., Bae, S. S., Lim, J. K., Matsumi, R., Lebedinsky, A. V., Sokolova, T. G., Kozhevnikova, D. A., Cha, S.-S.... (2010) Formate-driven growth coupled with H2 production. Nature, 467(7313), 352-355. DOI: 10.1038/nature09375  

  • September 16, 2010
  • 12:05 PM
  • 434 views

Uncovering Plagiarism in Biomedical Research

by Michael Long in Phased

Harold Garner (Virginia Bioinformatics Institute, United States) and coworkers have improved upon the eTBLAST tool for uncovering plagiarism in the technical science literature. This news feature was written on September 16, 2010.... Read more »

  • September 15, 2010
  • 02:25 PM
  • 412 views

Improving the Quality of Medical News Reporting

by Michael Long in Phased

David Henry (Institute for Clinical Evaluative Sciences, Canada) and coworkers demonstrate that specialist health reporters deliver superior medical news reporting, with implications for news outlets facing financial pressure and competition from alternative media. This news feature was written on September 15, 2010.... Read more »

Wilson, A., Robertson, J., McElduff, P., Jones, A., & Henry, D. (2010) Does It Matter Who Writes Medical News Stories?. PLoS Medicine, 7(9). DOI: 10.1371/journal.pmed.1000323  

  • September 14, 2010
  • 02:55 PM
  • 529 views

How Ebola-Infected Cells Evade the Immune System

by Michael Long in Phased

Paul Bates (University of Pennsylvania, United States) and coworkers have shown that Ebola-infected cells express a glycoprotein on the cell surface that shields the cells from the cell-mediated immune system, a finding which is also relevant to HIV and certain cancers. This news feature was written on September 14, 2010.... Read more »

  • September 13, 2010
  • 03:43 PM
  • 519 views

Wyeth's Ghostwriters Falsely Promoted Hormone Replacement Therapy

by Michael Long in Phased

Adriane Fugh-Berman (Georgetown University, United States) exposes the campaign of Wyeth and DesignWrite to falsely market hormone replacement therapy in non-symptomatic women, thereby profiting from a medical treatment which is not based on science. This news feature was written on September 13, 2010.... Read more »

  • September 12, 2010
  • 08:10 PM
  • 673 views

Did Comet Impacts Catalyze Amino Acid Production in Pre-Life Earth?

by Michael Long in Phased

Nir Goldman (Lawrence Livermore National Laboratory, United States) and coworkers' computer simulations suggest that the high temperatures and pressures of cometary impacts are sometimes within a range compatible with comets as a catalyst for amino acid synthesis in pre-life Earth. This news feature was written on September 12, 2010.... Read more »

  • September 12, 2010
  • 03:55 PM
  • 350 views

The Extent of Human Genetic Variation

by Michael Long in Phased

David Goldstein (Duke University, United States) and coworkers report steps towards unraveling the extent of human genetic variation, useful for directing medical effort towards genes critical to life. This news feature was written on September 12, 2010.... Read more »

Pelak, K., Shianna, K. V., Ge, D., Maia, J. M., Zhu, M., Smith, J. P., Cirulli, E. T., Fellay, J., Dickson, S. P., Gumbs, C. E.... (2010) The Characterization of Twenty Sequenced Human Genomes. PLoS Genetics, 6(9). DOI: 10.1371/journal.pgen.1001111  

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