5 posts · 3,108 views
September 5th saw the simultaneous publication of more than 30 papers in Nature, Genome Research and Genome Biology detailing the findings of the ENCODE project (Encyclopedia of DNA Elements)—an international collaborative research effort involving the work of more than 400 scientists in 32 groups over the last eight years. Building on the work of the [...]... Read more »
ENCODE Project Consortium, Bernstein BE, Birney E, Dunham I, Green ED, Gunter C, & Snyder M. (2012) An integrated encyclopedia of DNA elements in the human genome. Nature, 489(7414), 57-74. PMID: 22955616
Gerstein MB, Bruce C, Rozowsky JS, Zheng D, Du J, Korbel JO, Emanuelsson O, Zhang ZD, Weissman S, & Snyder M. (2007) What is a gene, post-ENCODE? History and updated definition. Genome research, 17(6), 669-81. PMID: 17567988
Anyone who has travelled across time zones knows how unpleasant it is when the regular rhythm of your biological clock is disrupted. Jetlag results when the body’s internal clock, or circadian rhythm is out of sync with external cues for “day and “night”, resulting in insomnia, extreme tiredness, difficulty concentrating and various other unpleasant symptoms. [...]... Read more »
Narasimamurthy R, Hatori M, Nayak SK, Liu F, Panda S, & Verma IM. (2012) Circadian clock protein cryptochrome regulates the expression of proinflammatory cytokines. Proceedings of the National Academy of Sciences of the United States of America, 109(31), 12662-7. PMID: 22778400
This is probably old news for neuroscientists and YouTube regulars, but it was news to me. I thought I would write a post about it, in case, like me, you are not one of the 4 million or so who have already seen the video of Snowball, the dancing Cockatoo, or heard about how he [...]... Read more »
Patel, A., Iversen, J., Bregman, M., & Schulz, I. (2009) Experimental Evidence for Synchronization to a Musical Beat in a Nonhuman Animal. Current Biology, 19(10), 827-830. DOI: 10.1016/j.cub.2009.03.038
On Saturday I ran 12 miles. “Well, at least I have staved off apoptosis in my peripheral blood mononuclear cells” I thought as I hobbled down the stairs on Sunday morning. Normally I don’t think about mononuclear cells on Sunday mornings, only of coffee. However, a paper published last week in BMC Physiology changed that [...]... Read more »
Marfe, G., Tafani, M., Pucci, B., Di Stefano, C., Indelicato, M., Andreoli, A., Russo, M., Manzi, V., & Sinibaldi-Salimei, P. (2010) The effect of marathon on mRNA expression of anti-apoptotic and pro-apoptotic proteins and sirtuins family in male recreational long-distance runners. BMC Physiology, 10(1), 7. DOI: 10.1186/1472-6793-10-7
Did you know that the microorganisms living in and on the human body (most on the skin, in the gut, and in the mouth) outnumber all our human cells by a factor of ten? But read on before you grab the hand sanitizer and schedule a colonic, these “germs” may be an integral [...]... Read more »
Fierer, N., Lauber, C., Zhou, N., McDonald, D., Costello, E., & Knight, R. (2010) Forensic identification using skin bacterial communities. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1000162107
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