A. Goldstein

64 posts · 38,079 views

WiSci is a blog that aims to provide interesting, informative posts about discoveries, debates, and dilemmas within the life sciences. This blog, formerly known as Beyond the Bench, attempts to reach any reader who has an interest in science and provide him or her with an accessible gateway into professionally published science content, whether by analyzing a journal article, interviewing a book author, or pointing out pieces written on other blogs.

WiSci
64 posts

Sort by Latest Post, Most Popular

View by Condensed, Full

  • March 2, 2011
  • 08:10 AM
  • 1,017 views

Weed Biology and Climate Change

by A. Goldstein in WiSci

Homeowners detest dandelions, and hikers abhor poison ivy. However, as pesky and unwanted as they often are, weeds’ stubborn resilience makes them well worth studying, especially as climate change affects plant life around the world. To find out more, we interviewed Dr. Lewis Ziska and Dr. Jeffrey Dukes, two editors who worked on the recently [...]... Read more »

James I.L. Morison, Michael D. Morecroft, Lewis H. Ziska, & James A. Bunce. (2007) Chapter 2. Plant Responses to Rising Atmospheric Carbon Dioxide. Plant Growth and Climate Change. DOI: 10.1002/9780470988695.ch2  

David M. Richardson, & Jeffrey S. Dukes. (2010) 26. Responses of Invasive Species to a Changing Climate and Atmosphere. Fifty Years of Invasion Ecology: The Legacy of Charles Elton. info:/10.1002/9781444329988.ch26

  • February 24, 2011
  • 10:11 AM
  • 1,224 views

Curing Cancer with Dwarfism, Down syndrome, and Vegetables

by A. Goldstein in WiSci

With the world abuzz about dwarfism preventing cancer, we wondered: what other sorts of genetic tinkering can, unexpectedly, prevent or cure cancer? Dwarfism Laron syndrome is a genetic disorder that causes dwarfism. Individuals with Laron syndrome possess a mutation on the GHR gene, rendering the gene defective and body insensitive to human growth hormone—hence stunted [...]... Read more »

Guevara-Aguirre, J., Balasubramanian, P., Guevara-Aguirre, M., Wei, M., Madia, F., Cheng, C., Hwang, D., Martin-Montalvo, A., Saavedra, J., Ingles, S.... (2011) Growth Hormone Receptor Deficiency Is Associated with a Major Reduction in Pro-Aging Signaling, Cancer, and Diabetes in Humans. Science Translational Medicine, 3(70), 70-70. DOI: 10.1126/scitranslmed.3001845  

Baek, K., Zaslavsky, A., Lynch, R., Britt, C., Okada, Y., Siarey, R., Lensch, M., Park, I., Yoon, S., Minami, T.... (2009) Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1. Nature, 459(7250), 1126-1130. DOI: 10.1038/nature08062  

Wang, X., Di Pasqua, A., Govind, S., McCracken, E., Hong, C., Mi, L., Mao, Y., Wu, J., Tomita, Y., Woodrick, J.... (2011) Selective Depletion of Mutant p53 by Cancer Chemopreventive Isothiocyanates and Their Structure−Activity Relationships. Journal of Medicinal Chemistry, 54(3), 809-816. DOI: 10.1021/jm101199t  

  • February 9, 2011
  • 03:04 PM
  • 921 views

Stopping HIV in the Macrophage

by A. Goldstein in WiSci

HIV is an elusive virus. Affecting more than 30 million people worldwide, the virus thrives in the human immune system by adapting in a number of ways, which makes effective treatments and an eventual cure exceedingly difficult. However, scientists at the University of Rochester and Emory University recently unveiled one of the mechanisms by which [...]... Read more »

Benaroch, P., Billard, E., Gaudin, R., Schindler, M., & Jouve, M. (2010) HIV-1 assembly in macrophages. Retrovirology, 7(1), 29. DOI: 10.1186/1742-4690-7-29  

  • January 26, 2011
  • 01:58 PM
  • 579 views

Michael Lea: Moringa oleifera tree, low-cost water purification

by A. Goldstein in WiSci

Mindbogglingly useful: a new, low-cost water purification protocol for the developing world now freely available* to download from CP Microbiology: Unit 1G.2 Bioremediation of Turbid Surface Water Using Seed Extract from Moringa oleifera Lam. (Drumstick) Tree In the Hitch-hiker’s Guide to the Galaxy, Douglas Adams described his fictional creation, the all language-translating Babel fish, as [...]... Read more »

  • January 20, 2011
  • 10:06 AM
  • 581 views

Exercise First, Eat Later

by A. Goldstein in WiSci

They say that breakfast is the most important meal of the day. Yet, as counter-intuitive as it may seem, research suggests that you may want to wait to eat your banana and peanut butter toast until after a morning workout. One practical benefit of eating breakfast in the morning is to lessen feelings of hunger [...]... Read more »

Pereira MA, Erickson E, McKee P, Schrankler K, Raatz SK, Lytle LA, & Pellegrini AD. (2011) Breakfast frequency and quality may affect glycemia and appetite in adults and children. The Journal of nutrition, 141(1), 163-8. PMID: 21123469  

Berkey, C., Rockett, H., Gillman, M., Field, A., & Colditz, G. (2003) Longitudinal study of skipping breakfast and weight change in adolescents. International Journal of Obesity, 27(10), 1258-1266. DOI: 10.1038/sj.ijo.0802402  

Van Proeyen K, Szlufcik K, Nielens H, Pelgrim K, Deldicque L, Hesselink M, Van Veldhoven PP, & Hespel P. (2010) Training in the fasted state improves glucose tolerance during fat-rich diet. The Journal of physiology, 588(Pt 21), 4289-302. PMID: 20837645  

Van Proeyen K, Szlufcik K, Nielens H, Ramaekers M, & Hespel P. (2011) Beneficial metabolic adaptations due to endurance exercise training in the fasted state. Journal of applied physiology (Bethesda, Md. : 1985), 110(1), 236-45. PMID: 21051570  

Schabort EJ, Bosch AN, Weltan SM, & Noakes TD. (1999) The effect of a preexercise meal on time to fatigue during prolonged cycling exercise. Medicine and science in sports and exercise, 31(3), 464-71. PMID: 10188753  

  • January 6, 2011
  • 03:35 PM
  • 803 views

Video Games Enhance Visual Attention

by A. Goldstein in WiSci

Video games might cause aggressive behavior,1 and they may contribute to childhood obesity,2 but recent research by Daphne Bavelier and her colleagues at the University of Rochester suggests that playing video games can have at least one benefit: they enhance visual attention. Visual attention is the mental mechanism we use to select relevant visual information [...]... Read more »

  • December 13, 2010
  • 10:12 AM
  • 669 views

The Vitamin D Controversy

by A. Goldstein in WiSci

Vitamin D could quite possibly be one of the most controversial supplements of the decade. Deficiency can cause rickets (in children) or osteoporosis, and experts such as Dr. Michael Holick of Boston University assert that the average modern-world citizen doesn’t get enough.1 Alternatively, other researchers such as Dr. Clifford Rosen of the Maine Medical Center [...]... Read more »

Sullivan SS, Rosen CJ, Halteman WA, Chen TC, . (2005) Adolescent Girls in Maine Are at Risk for Vitamin D Insufficiency. Journal of the American Dietetic Association, 105(6), 971-974. DOI: 10.1016/j.jada.2005.03.002  

Ross AC, Manson JE, Abrams SA, Aloia JF, Brannon PM, Clinton SK, Durazo-Arvizu RA, Gallagher JC, Gallo RL, Jones G.... (2010) The 2011 Report on Dietary Reference Intakes for Calcium and Vitamin D from the Institute of Medicine: What Clinicians Need to Know. The Journal of clinical endocrinology and metabolism. PMID: 21118827  

  • December 6, 2010
  • 08:28 AM
  • 519 views

Can Arsenic Replace Phosphorus? One Bacterium Says “Yes”

by A. Goldstein in WiSci

Up until a few days ago, scientists believed that all life forms on Earth were composed of six elements: carbon, hydrogen, nitrogen, oxygen, sulfur, and phosphorus. Then, on December 2, 2010, NASA researchers made a discovery that forced scientists everywhere to reconsider this belief: a bacterium that can replace phosphorus with arsenic.1 Typically, arsenic is [...]... Read more »

Wolfe-Simon, F., Blum, J., Kulp, T., Gordon, G., Hoeft, S., Pett-Ridge, J., Stolz, J., Webb, S., Weber, P., Davies, P.... (2010) A Bacterium That Can Grow by Using Arsenic Instead of Phosphorus. Science. DOI: 10.1126/science.1197258  

  • November 10, 2010
  • 10:05 AM
  • 506 views

Were the winters really colder when grandfather was a boy?

by A. Goldstein in WiSci

People tend to assume that scientists have only begun to find answers to climate change questions in the last few years. However, the following recording from 1956 offers evidence that climate change has been under scrutiny for over a century. Scientists have been noting upward temperature trends and glacial shrinkage since 1890, and carbon dioxide [...]... Read more »

  • November 4, 2010
  • 03:06 PM
  • 790 views

Stress: Does Gender Matter?

by A. Goldstein in WiSci

According to the Anxiety Disorders Association of America, 40 million Americans suffer from anxiety disorders—over twice the number of people who suffer from alcoholism,1 and nearly three times the number who suffer from depression.2 Of these 40 million people, two-thirds are female. While culture and environment might play contributing roles, science suggests that women may [...]... Read more »

  • October 26, 2010
  • 11:13 AM
  • 855 views

Worldwide Drought: Current Conditions and Future Predictions

by A. Goldstein in WiSci

From rising temperatures to rising seas, the consequences of global warming are here now, and predictions for the future are dire. In his review “Drought under global warming,” UCAR author Aiguo Dai indicates that yet another consequence is already affecting our planet and, over time, will almost certainly become more severe: worldwide drought. Wait, drought [...]... Read more »

  • October 22, 2010
  • 08:24 AM
  • 595 views

Geim and Novoselov Isolate Graphene, Win 2010 Nobel Prize in Physics

by A. Goldstein in WiSci

It is 100 times stronger than steel and the best heat conductor known to man. Most people have produced this substance unwittingly, yet it could be used to substantially improve computer chips, solar cells, and even satellites. What is this astonishing material? The first truly 2-dimensional crystalline material: graphene. This year, two pioneering physicists received [...]... Read more »

Tsoukleri, G., Parthenios, J., Papagelis, K., Jalil, R., Ferrari, A., Geim, A., Novoselov, K., & Galiotis, C. (2009) Subjecting a Graphene Monolayer to Tension and Compression. Small, 5(21), 2397-2402. DOI: 10.1002/smll.200900802  

  • October 14, 2010
  • 12:36 PM
  • 526 views

Fitter Kids = Bigger Brains

by agoldstein in WiSci

Parents take note: if you want your kids to grow bigger brains, think twice about letting schools cut recess or skimp on physical education.

Animal and human studies have long shown that exercise increases neurogenesis, especially in memory- and learning-related areas of the brain. More recently, research on human adolescents has not only confirmed these findings, but highlighted the importance of physical activity for children.... Read more »

Chaddock, L., Erickson, K., Prakash, R., VanPatter, M., Voss, M., Pontifex, M., Raine, L., Hillman, C., & Kramer, A. (2010) Basal Ganglia Volume Is Associated with Aerobic Fitness in Preadolescent Children. Developmental Neuroscience, 32(3), 249-256. DOI: 10.1159/000316648  

van Praag, H., Lucero, M., Yeo, G., Stecker, K., Heivand, N., Zhao, C., Yip, E., Afanador, M., Schroeter, H., Hammerstone, J.... (2007) Plant-Derived Flavanol (-)Epicatechin Enhances Angiogenesis and Retention of Spatial Memory in Mice. Journal of Neuroscience, 27(22), 5869-5878. DOI: 10.1523/JNEUROSCI.0914-07.2007  

  • October 1, 2010
  • 09:16 AM
  • 515 views

Frankenfish: Genetically Modified Salmon

by A. Goldstein in WiSci

Critics call them “frankenfish.” Advocates call them delicious. Either way, a genetically engineered salmon may be served up on your plate sooner than you think. In the United States, over 90% of corn, cotton, soybeans, and sugar beets we grow and consume are already genetically modified (GM). Therefore, the absence of GM animals may seem [...]... Read more »

Richt, J., Kasinathan, P., Hamir, A., Castilla, J., Sathiyaseelan, T., Vargas, F., Sathiyaseelan, J., Wu, H., Matsushita, H., Koster, J.... (2006) Production of cattle lacking prion protein. Nature Biotechnology, 25(1), 132-138. DOI: 10.1038/nbt1271  

  • September 17, 2010
  • 10:11 AM
  • 554 views

Brain Port: Seeing With Your Tongue

by A. Goldstein in WiSci

It sounds like a science fiction movie: a blind man wearing sunglasses licks a plastic lollipop and can suddenly see. This device, however, exists today. The Brain Port—a contraption comprised of a tiny video camera attached to a pair of sunglasses linked to a plastic “lollipop”—is enabling the blind to see . . . with [...]... Read more »

BACH-Y-RITA, P., COLLINS, C., SAUNDERS, F., WHITE, B., & SCADDEN, L. (1969) Vision Substitution by Tactile Image Projection. Nature, 221(5184), 963-964. DOI: 10.1038/221963a0  

  • September 17, 2010
  • 10:09 AM
  • 490 views

Brain Port: Seeing With Your Tongue

by agoldstein in WiSci

It sounds like a science fiction movie: a blind man wearing sunglasses licks a plastic lollipop and can suddenly see. This device, however, exists today. The Brain Port—a contraption comprised of a tiny video camera attached to a pair of sunglasses linked to a plastic “lollipop”—is enabling the blind to see . . . with their tongues.... Read more »

BACH-Y-RITA, P., COLLINS, C., SAUNDERS, F., WHITE, B., & SCADDEN, L. (1969) Vision Substitution by Tactile Image Projection. Nature, 221(5184), 963-964. DOI: 10.1038/221963a0  

  • September 8, 2010
  • 03:23 PM
  • 994 views

Finding the Gene for Migraines

by agoldstein in WiSci

Migraine headaches affect 1 in 6 women and 1 in 12 men, and can be triggered by any number of seemingly innocuous events, from eating cheese, to taking birth control pills, to exercising. In 2009, people worldwide spent $2.6 billion on preventative drugs, trying treatments from beta-blockers to anticonvulsants.1 Yet, despite being considered the most expensive brain disorder in the European Union and United States, the source of migraines has remained elusive . . . until now.... Read more »

  • August 25, 2010
  • 08:16 AM
  • 484 views

Bacterial Fingerprinting: A Microbial Future on CSI?

by A. Goldstein in WiSci

In 1915, detectives dusted for physical fingerprints. In 1990, they started using PCR (polymerase chain reaction) to determine DNA fingerprints from bits of hair and skin. In 2020, scientists might be identifying culprits with a whole new type of fingerprint: a bacterial fingerprint. A bacterial fingerprint is a unique mix of microbes by which an [...]... Read more »

Fierer, N., Lauber, C., Zhou, N., McDonald, D., Costello, E., & Knight, R. (2010) From the Cover: Forensic identification using skin bacterial communities. Proceedings of the National Academy of Sciences, 107(14), 6477-6481. DOI: 10.1073/pnas.1000162107  

Tucker JB, & Koblentz GD. (2009) The four faces of microbial forensics. Biosecurity and bioterrorism : biodefense strategy, practice, and science, 7(4), 389-97. PMID: 20028247  

  • August 25, 2010
  • 08:15 AM
  • 543 views

Bacterial Fingerprinting: A Microbial Future on CSI?

by agoldstein in WiSci

In 1915, detectives dusted for physical fingerprints. In 1990, they started using PCR (polymerase chain reaction) to extract DNA fingerprints from bits of hair and skin. In 2020, scientists might be identifying culprits with a whole new type of fingerprint: a bacterial fingerprint.... Read more »

Fierer, N., Lauber, C., Zhou, N., McDonald, D., Costello, E., & Knight, R. (2010) From the Cover: Forensic identification using skin bacterial communities. Proceedings of the National Academy of Sciences, 107(14), 6477-6481. DOI: 10.1073/pnas.1000162107  

Tucker JB, & Koblentz GD. (2009) The four faces of microbial forensics. Biosecurity and bioterrorism : biodefense strategy, practice, and science, 7(4), 389-97. PMID: 20028247  

  • August 18, 2010
  • 04:13 PM
  • 468 views

Is Seaweed the New Diet Food?

by agoldstein in WiSci

Diet medications may damage your liver, low-carbohydrate diets can cause kidney failure, and gastric bypass carries with it all the risks and complications of any body-altering surgery. However, recent research has suggested a slightly less risky fat-fighting alternative: seaweed.... Read more »

Brownlee, I., Allen, A., Pearson, J., Dettmar, P., Havler, M., Atherton, M., & Onsøyen, E. (2005) Alginate as a Source of Dietary Fiber. Critical Reviews in Food Science and Nutrition, 45(6), 497-510. DOI: 10.1080/10408390500285673  

Iain A. Brownlee, Chris J. Seal, Matthew Wilcox, Peter W. Dettmar and Jeff P. Pearson. (2009) Applications of Alginates in Food. Microbiology Monographs, 211-228. DOI: 10.1007/978-3-540-92679-5_9  

MacArtain, P., Gill, C., Brooks, M., Campbell, R., & Rowland, I. (2007) Nutritional Value of Edible Seaweeds. Nutrition Reviews, 65(12), 535-543. DOI: 10.1111/j.1753-4887.2007.tb00278.x  

join us!

Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.

If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.

Register Now

Research Blogging is powered by SMG Technology.

To learn more, visit seedmediagroup.com.