7 posts · 2,715 views
TLneuro
6 posts
Sort by Latest Post, Most Popular
View by Condensed, Full
- March 23, 2011
- 02:47 PM
- 835 views
Web-based survey on mephedrone use
A recent Web-based survey paper from Carhart-Harris and colleagues gives us another look at the mephedrone (4-methylmethcathinone; 4-MMC) using population (see Winstock et al, 2011 for additional). The 4-MMC compound is a derivative of cathinone, the active constituent of the plant material khat which is chewed by populations from the Arabian Peninsula and the Horn [...]... Read more »
Winstock AR, Mitcheson LR, Deluca P, Davey Z, Corazza O, & Schifano F. (2011) Mephedrone, new kid for the chop?. Addiction (Abingdon, England), 106(1), 154-61. PMID: 20735367
Carhart-Harris RL, King LA, & Nutt DJ. (2011) A web-based survey on mephedrone. Drug and alcohol dependence. PMID: 21420252
- July 6, 2011
- 01:59 PM
- 461 views
Mephedrone Neurochemistry: MDMA-like?
A discussion of the first report on in vivo neurochemical responses to mephedrone.... Read more »
Kehr, J., Ichinose, F., Yoshitake, S., Goiny, M., Sievertsson, T., Nyberg, F., & Yoshitake, T. (2011) Mephedrone, compared to MDMA (ecstasy) and amphetamine, rapidly increases both dopamine and serotonin levels in nucleus accumbens of awake rats. British Journal of Pharmacology. DOI: 10.1111/j.1476-5381.2011.01499.x
- November 19, 2010
- 01:44 PM
- 426 views
Cosgrove et al, 2002: Wheel running suppresses cocaine taking
In 2008 at the Annual Meeting of CPDD, I heard Nora Volkow, Director of NIDA, describe a new interest of NIDA in the role that regular exercise plays in preventing or ameliorating drug use. Some of the rationale was epidemiological, you may think of this as “adolescents who are in sports are less likely to [...]... Read more »
Cosgrove KP, Hunter RG, & Carroll ME. (2002) Wheel-running attenuates intravenous cocaine self-administration in rats: sex differences. Pharmacology, biochemistry, and behavior, 73(3), 663-71. PMID: 12151042
- March 28, 2012
- 11:02 AM
- 325 views
The Mephedrone Conundrum
Recent reports from the UK Advisory Council on the Misuse of Drugs (Iversen et al. 2010) and the Europol-European Monitoring Centre for Drugs and Drug Addiction (Sedefov et al. 2010) emphasize that very little scientific information on substituted cathinones is available. Understanding of the effects of these compounds is at present by reference to the parent compound cathinone (found in khat, a plant material chewed for similant properties in the Horn of Africa and Arabian peninsula) and methcathinone. Cathinone is structurally similar to amphetamine and findings with various substituted amphetamine compounds suggests that modifications to the core structure can confer very different pharmacological properties, abuse liabilities and toxicological risks. ... Read more »
Baumann, M., Ayestas, M., Partilla, J., Sink, J., Shulgin, A., Daley, P., Brandt, S., Rothman, R., Ruoho, A., & Cozzi, N. (2011) The Designer Methcathinone Analogs, Mephedrone and Methylone, are Substrates for Monoamine Transporters in Brain Tissue. Neuropsychopharmacology, 37(5), 1192-1203. DOI: 10.1038/npp.2011.304
Hadlock GC, Webb KM, McFadden LM, Chu PW, Ellis JD, Allen SC, Andrenyak DM, Vieira-Brock PL, German CL, Conrad KM.... (2011) 4-Methylmethcathinone (mephedrone): neuropharmacological effects of a designer stimulant of abuse. The Journal of pharmacology and experimental therapeutics, 339(2), 530-6. PMID: 21810934
Kehr, J., Ichinose, F., Yoshitake, S., Goiny, M., Sievertsson, T., Nyberg, F., & Yoshitake, T. (2011) Mephedrone, compared to MDMA (ecstasy) and amphetamine, rapidly increases both dopamine and serotonin levels in nucleus accumbens of awake rats. British Journal of Pharmacology. DOI: 10.1111/j.1476-5381.2011.01499.x
Winder, G., Stern, N., & Hosanagar, A. (2012) Are “Bath Salts” the next generation of stimulant abuse?. Journal of Substance Abuse Treatment. DOI: 10.1016/j.jsat.2012.02.003
- March 27, 2012
- 01:52 PM
- 291 views
Cognitive impairment in Khat users
A recent paper described cognitive deficits in a group of chronic Khat users.... Read more »
Colzato LS, Ruiz MJ, van den Wildenberg WP, & Hommel B. (2011) Khat use is associated with impaired working memory and cognitive flexibility. PloS one, 6(6). PMID: 21698275
- November 12, 2010
- 11:56 AM
- 198 views
Does it matter which kind of cannabis you smoke?
A finding that cannabidiol content of smoked cannabis protects against memory impairment.... Read more »
Morgan CJ, Schafer G, Freeman TP, & Curran HV. (2010) Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study: naturalistic study [corrected]. The British journal of psychiatry : the journal of mental science, 197(4), 285-90. PMID: 20884951
- September 15, 2011
- 10:45 AM
- 179 views
Marijuana use trajectories in at-risk boys
by mtaffe in Scripps Center for Cannabis Addiction Neurobiology
Longitudinal study of at-risk boys shows some age out, some continue marijuana use. ... Read more »
Finlay, A., White, H., Mun, E., Cronley, C., & Lee, C. (2012) Racial differences in trajectories of heavy drinking and regular marijuana use from ages 13 to 24 among African-American and White males. Drug and Alcohol Dependence, 121(1-2), 118-123. DOI: 10.1016/j.drugalcdep.2011.08.020
topics
join us!
Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.
If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.
