Shaheen Lakhan

328 posts · 199,610 views

Brain Blogger covers topics from multidimensional biopsychosocial perspectives. It reviews the latest news and stories related to neuroscience, psychiatry, and neurology. It serves as a focal point for attracting new minds beyond the science of the mind-and-brain and into the biopsychosocial model.

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  • July 12, 2010
  • 08:00 AM
  • 89 views

Mind your Immune System

by Shaheen Lakhan in Brain Blogger

Another significant piece in the mind-body puzzle comes from this new study where obsessive-compulsive behavior in mice was cured by a bone marrow transplant. A rare form of a genetic disorder in mice causes a “hair pulling” disorder, very similar to its human counterpart trichotillomania. In their new findings published in Cell, Mario Capecchi and [...]... Read more »

Chen SK, Tvrdik P, Peden E, Cho S, Wu S, Spangrude G, & Capecchi MR. (2010) Hematopoietic origin of pathological grooming in Hoxb8 mutant mice. Cell, 141(5), 775-85. PMID: 20510925  

  • July 9, 2010
  • 08:00 AM
  • 115 views

The Handwriting on the Wall

by Shaheen Lakhan in Brain Blogger

Children with autism spectrum disorder (ASD) often have poor penmanship. In turn, poor penmanship leads to decreased success in communication, failed academics, and a lack of self-esteem. Until now, clinicians and autism experts believed that developmental delays were to blame for inferior handwriting skills, but a new study in Neurology reports that weak motor skills [...]... Read more »

Beversdorf DQ, Anderson JM, Manning SE, Anderson SL, Nordgren RE, Felopulos GJ, & Bauman ML. (2001) Brief report: macrographia in high-functioning adults with autism spectrum disorder. Journal of autism and developmental disorders, 31(1), 97-101. PMID: 11439759  

Dziuk MA, Gidley Larson JC, Apostu A, Mahone EM, Denckla MB, & Mostofsky SH. (2007) Dyspraxia in autism: association with motor, social, and communicative deficits. Developmental medicine and child neurology, 49(10), 734-9. PMID: 17880641  

Frings M, Gaertner K, Buderath P, Christiansen H, Gerwig M, Hein-Kropp C, Schoch B, Hebebrand J, & Timmann D. (2010) Megalographia in Children with Cerebellar Lesions and in Children with Attention-Deficit/Hyperactivity Disorder. Cerebellum (London, England). PMID: 20480275  

Fuentes CT, Mostofsky SH, & Bastian AJ. (2009) Children with autism show specific handwriting impairments. Neurology, 73(19), 1532-7. PMID: 19901244  

  • July 3, 2010
  • 02:24 PM
  • 153 views

The Bold and the Beautiful

by Shaheen Lakhan in Brain Blogger

Personality is a complicated interplay of traits that influence well-being, cognition and mental health. The so-called Big Five personality traits include extraversion, agreeableness, conscientiousness, neuroticism and openness. It is difficult to quantify personality characteristics and their roles in mood, behavior and reasoning, but several recent studies have proclaimed the significant effect of extraversion — the [...]... Read more »

Styśko-Kunkowska MA, & Borecka D. (2010) Extraversion and evaluation of humorous advertisements. Psychological reports, 106(1), 44-8. PMID: 20402425  

Terracciano A, McCrae RR, & Costa PT. (2010) Intra-individual Change in Personality Stability and Age. Journal of research in personality, 44(1), 31-37. PMID: 20305728  

  • June 26, 2010
  • 12:23 PM
  • 144 views

Only the Brain is Worried about Getting Fat

by Shaheen Lakhan in Brain Blogger

One thing that virtually all women share is body image issues. No matter how thin or fat, short or tall, or muscular or slim, women dislike something about their body. According to a new study published in the journal Personality and Individual Differences, even women who are seemingly well-adjusted with no overt body image issues have [...]... Read more »

Owens, T., Allen, M., & Spangler, D. (2010) An fMRI study of self-reflection about body image: Sex differences. Personality and Individual Differences, 48(7), 849-854. DOI: 10.1016/j.paid.2010.02.012  

  • June 22, 2010
  • 10:54 AM
  • 88 views

Goal Setting – Pitfalls and Benefits

by Shaheen Lakhan in Brain Blogger

Goal setting is a funny thing. Like many of you, I’m sure, I’ve had a long and checkered relationship with it. I’ve gone back and forth, was a big fan, hated it, went back to goal setting again. What is it that fascinates and repels about goal setting? I set out to look at some [...]... Read more »

  • June 17, 2010
  • 09:10 PM
  • 109 views

Medical Art Imitating Life

by Shaheen Lakhan in Brain Blogger

The ideal human body shape has evolved — for better or worse — over the course of human history. Its depiction in art parallels society’s beliefs regarding what is and is not attractive and desirable. The representation of the human form has, too, undergone a metamorphosis in the oft-forgotten field of medical illustration. With the [...]... Read more »

Bonafini BA, & Pozzilli P. (2010) Body weight and beauty: the changing face of the ideal female body weight. Obesity reviews : an official journal of the International Association for the Study of Obesity. PMID: 20492540  

Pearce JM. (2009) Henry Gray's Anatomy. Clinical anatomy (New York, N.Y.), 22(3), 291-5. PMID: 19280653  

  • June 12, 2010
  • 10:28 AM
  • 574 views

Female Teachers’ Math Anxiety Negatively Affects Female Students

by Shaheen Lakhan in Brain Blogger

For a long time it was believed that males have better spatial and numerical abilities resulting in their greater aptitude for mathematics compared to females. But research in cognitive development of human infants and children has failed to support these claims. Instead, scientists now have enough evidence to conclude that the same set of biologically [...]... Read more »

Beilock SL, Gunderson EA, Ramirez G, & Levine SC. (2010) Female teachers' math anxiety affects girls' math achievement. Proceedings of the National Academy of Sciences of the United States of America, 107(5), 1860-3. PMID: 20133834  

Hyde JS, Lindberg SM, Linn MC, Ellis AB, & Williams CC. (2008) Diversity. Gender similarities characterize math performance. Science (New York, N.Y.), 321(5888), 494-5. PMID: 18653867  

  • June 9, 2010
  • 08:00 AM
  • 123 views

Antidepressants Carry Equal Risks

by Shaheen Lakhan in Brain Blogger

For nearly a decade, the public has heeded warnings of suicidal behavior related to antidepressant use in children and adolescents. However, the use of antidepressants in this population is still increasing. Initially, selective serotonin reuptake inhibitors (SSRIs), the most common class of antidepressants prescribed for children, were the only drugs associated with the increase in [...]... Read more »

Jick H, Kaye JA, & Jick SS. (2004) Antidepressants and the risk of suicidal behaviors. JAMA : the journal of the American Medical Association, 292(3), 338-43. PMID: 15265848  

Schneeweiss S, Patrick AR, Solomon DH, Dormuth CR, Miller M, Mehta J, Lee JC, & Wang PS. (2010) Comparative safety of antidepressant agents for children and adolescents regarding suicidal acts. Pediatrics, 125(5), 876-88. PMID: 20385637  

Simon GE, Savarino J, Operskalski B, & Wang PS. (2006) Suicide risk during antidepressant treatment. The American journal of psychiatry, 163(1), 41-7. PMID: 16390887  

Vitiello B, Silva SG, Rohde P, Kratochvil CJ, Kennard BD, Reinecke MA, Mayes TL, Posner K, May DE, & March JS. (2009) Suicidal events in the Treatment for Adolescents With Depression Study (TADS). The Journal of clinical psychiatry, 70(5), 741-7. PMID: 19552869  

  • June 6, 2010
  • 08:00 AM
  • 130 views

Trick of the Light – Optical Illusions Can’t be Beat

by Shaheen Lakhan in Brain Blogger

You know ‘em, you love ‘em: Suddenly, pictures bulge out in three dimensions, or static dots begin to swirl, or you see colors that aren’t really there. Tricking your eye is as easy as the well-known “finger sausage” maneuver: Hold out your arms, point your index fingers toward each other, then move them slowly together [...]... Read more »

Kuriki I, Ashida H, Murakami I, & Kitaoka A. (2008) Functional brain imaging of the Rotating Snakes illusion by fMRI. Journal of vision, 8(10), 16-10. PMID: 19146358  

  • June 3, 2010
  • 08:00 AM
  • 147 views

Exercise – It Works For Depression

by Shaheen Lakhan in Brain Blogger

I’m currently reading with great pleasure Tony Schwartz’s new book, The Way We’re Working Isn’t Working – The Four Forgotten Needs That Energize Great Performance. Schwartz’s main premise is that we need balance — between activity and rest on the physical level, between performance and renewal on the emotional level, between left and right brain [...]... Read more »

Babyak M, Blumenthal JA, Herman S, Khatri P, Doraiswamy M, Moore K, Craighead WE, Baldewicz TT, & Krishnan KR. (2000) Exercise treatment for major depression: maintenance of therapeutic benefit at 10 months. Psychosomatic medicine, 62(5), 633-8. PMID: 11020092  

Blumenthal JA, Babyak MA, Moore KA, Craighead WE, Herman S, Khatri P, Waugh R, Napolitano MA, Forman LM, Appelbaum M.... (1999) Effects of exercise training on older patients with major depression. Archives of internal medicine, 159(19), 2349-56. PMID: 10547175  

  • May 31, 2010
  • 08:00 AM
  • 138 views

Life is Like a Box of Chocolates

by Shaheen Lakhan in Brain Blogger

Through the course of modern human history, chocolate has been considered the most special of all confections. Chocolate inspires deep love and devotion from those who partake of it, and its ability to enhance one’s mood has been advertised by men, women and children — and candy manufacturers — everywhere. Now, new evidence may put [...]... Read more »

Strandberg TE, Strandberg AY, Pitkälä K, Salomaa VV, Tilvis RS, & Miettinen TA. (2008) Chocolate, well-being and health among elderly men. European journal of clinical nutrition, 62(2), 247-53. PMID: 17327862  

Williams S, Tamburic S, & Lally C. (2009) Eating chocolate can significantly protect the skin from UV light. Journal of cosmetic dermatology, 8(3), 169-73. PMID: 19735513  

  • May 20, 2010
  • 08:00 AM
  • 131 views

Clinical Psychologists’ Perceptions of Persons with Mental Illness

by Shaheen Lakhan in Brain Blogger

Many people have fabulous relationships with their psychologists. They feel supported, understood, well-liked. But there are also those who feel a little uneasy. Research by Lynn Servais and Stephen Saunders of Marquette University in Milwaukee, Wisconsin may have unearthed one of the reasons why.
Some psychologists have a hard time connecting with people with mental illness, [...]... Read more »

Servais, L., & Saunders, S. (2007) Clinical psychologists' perceptions of persons with mental illness. Professional Psychology: Research and Practice, 38(2), 214-219. DOI: 10.1037/0735-7028.38.2.214  

  • May 17, 2010
  • 01:31 PM
  • 164 views

Take Two of These… And You Still Might Have Pain

by Shaheen Lakhan in Brain Blogger

Migraines are severe, often debilitating, headaches that may be accompanied by visual symptoms, as well as nausea and vomiting. Migraines may last up to 24 hours. The exact cause of migraine is unknown, and most treatment focuses on acute pain relief once the migraine begins. For many migraine sufferers, acute pain relief is often ineffective [...]... Read more »

Kirthi V, Derry S, Moore RA, & McQuay HJ. (2010) Aspirin with or without an antiemetic for acute migraine headaches in adults. Cochrane database of systematic reviews (Online). PMID: 20393963  

Lovell BV, & Marmura MJ. (2010) New therapeutic developments in chronic migraine. Current opinion in neurology, 23(3), 254-8. PMID: 20442572  

Paemeleire K, & Bartsch T. (2010) Occipital nerve stimulation for headache disorders. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 7(2), 213-9. PMID: 20430321  

  • May 10, 2010
  • 08:00 AM
  • 185 views

Antidepressants Not Effective for Some Types of Depression

by Shaheen Lakhan in Brain Blogger

Antidepressant medications have been the mainstay of treatment for depressive disorders for decades. But these drugs may not be as effective as once believed, according to a new analysis published in the Journal of the American Medical Association (JAMA). Researchers at the University of Pennsylvania conducted a meta-analysis of data from trials of antidepressants and [...]... Read more »

Fournier, J., DeRubeis, R., Hollon, S., Dimidjian, S., Amsterdam, J., Shelton, R., & Fawcett, J. (2010) Antidepressant Drug Effects and Depression Severity: A Patient-Level Meta-analysis. JAMA: The Journal of the American Medical Association, 303(1), 47-53. DOI: 10.1001/jama.2009.1943  

  • May 7, 2010
  • 08:00 AM
  • 194 views

Light at the End of the Tunnel or Too Much Carbon Dioxide?

by Shaheen Lakhan in Brain Blogger

The connection between mind and body is never as ambiguous as when the body is near death. Reports of near-death experiences (NDEs) in people who suffer cardiac arrest or other life-threatening traumas are unexplained by current science. Theories of psychological, physiological, and transcendental causes abound, but none has defined the true source of the phenomenon. [...]... Read more »

Lai CF, Kao TW, Wu MS, Chiang SS, Chang CH, Lu CS, Yang CS, Yang CC, Chang HW, Lin SL.... (2007) Impact of near-death experiences on dialysis patients: a multicenter collaborative study. American journal of kidney diseases : the official journal of the National Kidney Foundation, 50(1), 124. PMID: 17591532  

  • May 4, 2010
  • 08:00 AM
  • 172 views

Always Look on the Bright Side of Life

by Shaheen Lakhan in Brain Blogger

Winston Churchill once defined a pessimist as one who sees the difficulty in every opportunity, but an optimist as one who sees the opportunity in every difficulty. New research shows that optimists, who already enjoy better goal attainment, more resilience, and better overall well-being compared to pessimists, also enjoy a healthier immune system. The new [...]... Read more »

Avitsur, R., Powell, N., Padgett, D., & Sheridan, J. (2009) Social Interactions, Stress, and Immunity. Immunology and Allergy Clinics of North America, 29(2), 285-293. DOI: 10.1016/j.iac.2009.02.006  

Segerstrom, S. (2007) Stress, Energy, and Immunity: An Ecological View. Current Directions in Psychological Science, 16(6), 326-330. DOI: 10.1111/j.1467-8721.2007.00522.x  

  • May 1, 2010
  • 08:00 AM
  • 215 views

Societal Assumptions on Abuse and the Victim’s Perspective

by Shaheen Lakhan in Brain Blogger

Sexual abuse of children is morally revolting and a topic wrought with emotions. In the past few decades, awareness of the prevalence of child abuse and its psychological repercussions has increased. A “trauma model” has been built around sexual abuse that perceives it as being directly traumatic and frightening, and necessarily damaging.
Many psychologists now argue [...]... Read more »

Loftus, E., & Frenda, S. (2010) Bad Theories Can Harm Victims. Science, 327(5971), 1329-1330. DOI: 10.1126/science.1187716  

  • April 28, 2010
  • 08:00 AM
  • 196 views

The Brain Rejects Inequality

by Shaheen Lakhan in Brain Blogger

The human brain likes balance. Not simply biological and physiological homeostasis that maintains the proper functioning of the brain, but emotional, social and psychological balance. Notably, the human brain dislikes inequality when it comes to money, and rejects it at all costs, according to new research in the journal Nature.
Behavioral and anthropological evidence show that [...]... Read more »

Guroglu, B., van den Bos, W., Rombouts, S., & Crone, E. (2010) Unfair? It depends: Neural correlates of fairness in social context. Social Cognitive and Affective Neuroscience. DOI: 10.1093/scan/nsq013  

Smith, D., Hayden, B., Truong, T., Song, A., Platt, M., & Huettel, S. (2010) Distinct Value Signals in Anterior and Posterior Ventromedial Prefrontal Cortex. Journal of Neuroscience, 30(7), 2490-2495. DOI: 10.1523/JNEUROSCI.3319-09.2010  

Tricomi, E., Rangel, A., Camerer, C., & O’Doherty, J. (2010) Neural evidence for inequality-averse social preferences. Nature, 463(7284), 1089-1091. DOI: 10.1038/nature08785  

Yamagishi, T., Horita, Y., Takagishi, H., Shinada, M., Tanida, S., & Cook, K. (2009) The private rejection of unfair offers and emotional commitment. Proceedings of the National Academy of Sciences, 106(28), 11520-11523. DOI: 10.1073/pnas.0900636106  

  • April 25, 2010
  • 08:00 AM
  • 269 views

Good Health Equals Good Sex

by Shaheen Lakhan in Brain Blogger

Sexuality is an important component of overall health and quality of life. An active sex life can reduce stress, strengthen the immune system, improve cardiovascular health and promote longevity. Not only does sex lead to health benefits, but good health leads to improved sexuality. A recent British Medical Journal (BMJ) report concluded that the better [...]... Read more »

  • April 22, 2010
  • 08:00 AM
  • 223 views

The Neurobiology of Social Anxiety Disorder

by Shaheen Lakhan in Brain Blogger

Shyness is a unique trait and all of us experience it in various degrees when faced with performance situations or new social surroundings. However, many people go through life dreading such encounters and exposure to the feared social situation provokes anxiety, or possibly a panic attack. Social anxiety disorder (SAD) or social phobia is a [...]... Read more »

Stein, M., & Stein, D. (2008) Social anxiety disorder. The Lancet, 371(9618), 1115-1125. DOI: 10.1016/S0140-6736(08)60488-2  

Stein MB, & Gorman JM. (2001) Unmasking social anxiety disorder. Journal of psychiatry , 26(3), 185-9. PMID: 11394188  

Strug, L., Suresh, R., Fyer, A., Talati, A., Adams, P., Li, W., Hodge, S., Gilliam, T., & Weissman, M. (2008) Panic disorder is associated with the serotonin transporter gene (SLC6A4) but not the promoter region (5-HTTLPR). Molecular Psychiatry, 15(2), 166-176. DOI: 10.1038/mp.2008.79  

Smoller, J., Paulus, M., Fagerness, J., Purcell, S., Yamaki, L., Hirshfeld-Becker, D., Biederman, J., Rosenbaum, J., Gelernter, J., & Stein, M. (2008) Influence of RGS2 on Anxiety-Related Temperament, Personality, and Brain Function. Archives of General Psychiatry, 65(3), 298-308. DOI: 10.1001/archgenpsychiatry.2007.48  

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