435 posts · 451,911 views

Brain Blogger covers topics from multidimensional biopsychosocial perspectives. It reviews the latest news and stories related to neuroscience, psychiatry, and neurology. It serves as a focal point for attracting new minds beyond the science of the mind-and-brain and into the biopsychosocial model.

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June 17, 2011
08:00 AM
900 views

Brain Growth in Autism

by Shaheen Lakhan in Brain Blogger

Brain overgrowth has been noted among children with autism spectrum disorder (ASD). Now, a new imaging study suggests that the accelerated brain growth appears before 2 years of life, offering new avenues for early identification and intervention of ASD. Investigators conducted a longitudinal magnetic resonance imaging (MRI) study of 59 children with ASD and 38 [...]... Read more »

Cheng Y, Chou KH, Fan YT, & Lin CP. (2011) ANS: Aberrant Neurodevelopment of the Social Cognition Network in Adolescents with Autism Spectrum Disorders. PloS one, 6(4). PMID: 21541322

Courchesne E, Campbell K, & Solso S. (2011) Brain growth across the life span in autism: age-specific changes in anatomical pathology. Brain research, 138-45. PMID: 20920490

Courchesne E, Carper R, & Akshoomoff N. (2003) Evidence of brain overgrowth in the first year of life in autism. JAMA : the journal of the American Medical Association, 290(3), 337-44. PMID: 12865374

Courchesne E, Redcay E, & Kennedy DP. (2004) The autistic brain: birth through adulthood. Current opinion in neurology, 17(4), 489-96. PMID: 15247547

Hazlett HC, Poe MD, Gerig G, Styner M, Chappell C, Smith RG, Vachet C, & Piven J. (2011) Early brain overgrowth in autism associated with an increase in cortical surface area before age 2 years. Archives of general psychiatry, 68(5), 467-76. PMID: 21536976

Redcay E, & Courchesne E. (2005) When is the brain enlarged in autism? A meta-analysis of all brain size reports. Biological psychiatry, 58(1), 1-9. PMID: 15935993

June 14, 2011
08:00 AM
876 views

Genetic Link to Depression Identified

by Shaheen Lakhan in Brain Blogger

Many studies have shown a heritable component to depressive disorders, but a specific cause has not been identified. Recently, scientists in two separate studies located a specific chromosomal region that is associated with depression. Both studies were recently published in the American Journal of Psychiatry. One study was led by a team at Washington University [...]... Read more »

Breen G, Webb BT, Butler AW, van den Oord EJ, Tozzi F, Craddock N, Gill M, Korszun A, Maier W, Middleton L.... (2011) A Genome-Wide Significant Linkage for Severe Depression on Chromosome 3: The Depression Network Study. The American journal of psychiatry. PMID: 21572164

Lewis CM, Ng MY, Butler AW, Cohen-Woods S, Uher R, Pirlo K, Weale ME, Schosser A, Paredes UM, Rivera M.... (2010) Genome-wide association study of major recurrent depression in the U.K. population. The American journal of psychiatry, 167(8), 949-57. PMID: 20516156

Pergadia ML, Glowinski AL, Wray NR, Agrawal A, Saccone SF, Loukola A, Broms U, Korhonen T, Penninx BW, Grant JD.... (2011) A 3p26-3p25 Genetic Linkage Finding for DSM-IV Major Depression in Heavy Smoking Families. The American journal of psychiatry. PMID: 21572167

Shi J, Potash JB, Knowles JA, Weissman MM, Coryell W, Scheftner WA, Lawson WB, DePaulo JR Jr, Gejman PV, Sanders AR.... (2011) Genome-wide association study of recurrent early-onset major depressive disorder. Molecular psychiatry, 16(2), 193-201. PMID: 20125088

Uher R. (2011) Genes, environment, and individual differences in responding to treatment for depression. Harvard review of psychiatry, 19(3), 109-24. PMID: 21631158

Wray NR, Pergadia ML, Blackwood DH, Penninx BW, Gordon SD, Nyholt DR, Ripke S, Macintyre DJ, McGhee KA, Maclean AW.... (2010) Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned. Molecular psychiatry. PMID: 21042317

June 11, 2011
08:00 AM
621 views

Ambien, Sonata, and Lunesta – The Morning After

by Shaheen Lakhan in Brain Blogger

The latest generation of sleep hypnotics — Ambien (zolpidem), Sonata (zaleplon), and Lunesta (zopiclone) — have introduced new terms into the American lexicon. We now speak of people “sleep-driving” under the influence of these medications, for instance. The official guide that comes with Lunesta, to take one example, warns of the side effects this way: [...]... Read more »

Bocca ML, Marie S, Lelong-Boulouard V, Bertran F, Couque C, Desfemmes T, Berthelon C, Amato JN, Moessinger M, Paillet-Loilier M.... (2011) Zolpidem and zopiclone impair similarly monotonous driving performance after a single nighttime intake in aged subjects. Psychopharmacology, 214(3), 699-706. PMID: 21086117

Hesse, L., von Moltke, L., & Greenblatt, D. (2003) Clinically Important Drug Interactions with Zopiclone, Zolpidem and Zaleplon. CNS Drugs, 17(7), 513-532. DOI: 10.2165/00023210-200317070-00004

Otmani, S., Demazières, A., Staner, C., Jacob, N., Nir, T., Zisapel, N., & Staner, L. (2008) Effects of prolonged-release melatonin, zolpidem, and their combination on psychomotor functions, memory recall, and driving skills in healthy middle aged and elderly volunteers. Human Psychopharmacology: Clinical and Experimental, 23(8), 693-705. DOI: 10.1002/hup.980

June 8, 2011
08:00 AM
1,123 views

Health Care Market Equilibrium in a Changing Environment

by Shaheen Lakhan in Brain Blogger

Strategic market planning has always been a challenge in the rapidly changing health care industry. Both internal factors of unpredictability and external market threats create waves of instability in the health care market industry. For health care consumers, this often means fluctuating health care costs and unpredictable care availability. For health care providers, this means [...]... Read more »

Bonabeau E. (2004) The perils of the imitation age. Harvard business review, 82(6), 45. PMID: 15202286

Kumar K, Subramanian R, & Strandholm K. (2002) Market and efficiency-based strategic responses to environmental changes in the health care industry. Health care management review, 27(3), 21-31. PMID: 12146781

Schroeder, S. (2002) Primary Care at a Crossroads. Academic Medicine, 77(8), 767-773. DOI: 10.1097/00001888-200208000-00003

June 5, 2011
08:00 AM
782 views

Domestic Violence – Understanding is Getting More Nuanced

by Shaheen Lakhan in Brain Blogger

A few years ago I brain blogged about domestic violence (DV), focusing on how ideology, politics, and stereotypes were interfering with an effective social response. It got a big response, almost entirely supportive. At that time, the tide was turning because of lawsuits and a preponderance of research that were beginning to overwhelm the dominance [...]... Read more »

Ferguson, C. (2010) Genetic Contributions to Antisocial Personality and Behavior: A Meta-Analytic Review From an Evolutionary Perspective. The Journal of Social Psychology, 150(2), 160-180. DOI: 10.1080/00224540903366503

June 2, 2011
08:00 AM
687 views

Hold It! Stop Making Impulsive Decisions

by Shaheen Lakhan in Brain Blogger

To pee or not to pee? A new study published in Psychological Science says you may want to make important life decisions before finding that restroom. The study, conducted by a team in the Netherlands, evaluated how having a full bladder affected the ability to make decisions that required self-control. First, volunteers in the study [...]... Read more »

DeWall CN, Baumeister RF, Mead NL, & Vohs KD. (2011) How leaders self-regulate their task performance: evidence that power promotes diligence, depletion, and disdain. Journal of personality and social psychology, 100(1), 47-65. PMID: 20919772

Job V, Dweck CS, & Walton GM. (2010) Ego depletion--is it all in your head? implicit theories about willpower affect self-regulation. Psychological science : a journal of the American Psychological Society / APS, 21(11), 1686-93. PMID: 20876879

Kable JW, & Glimcher PW. (2010) An "as soon as possible" effect in human intertemporal decision making: behavioral evidence and neural mechanisms. Journal of neurophysiology, 103(5), 2513-31. PMID: 20181737

Martin LE, & Potts GF. (2009) Impulsivity in Decision-Making: An Event-Related Potential Investigation. Personality and individual differences, 46(3), 303-308. PMID: 20126284

Tuk MA, Trampe D, & Warlop L. (2011) Inhibitory spillover: increased urination urgency facilitates impulse control in unrelated domains. Psychological science : a journal of the American Psychological Society / APS, 22(5), 627-33. PMID: 21467548

May 30, 2011
08:00 AM
708 views

Electroconvulsive Therapy in Pediatric Psychiatry

by Shaheen Lakhan in Brain Blogger

Electroconvulsive therapy (ECT) is a controversial practice of dealing with mental disorders and one that has attracted its fair share of detractors. Despite the fact that it was first used as long ago as 1938, it still carries with it a stigma that some find difficult to overlook. One might believe this method is one [...]... Read more »

Avery D, & Winokur G. (1977) The efficacy of electroconvulsive therapy and antidepressants in depression. Biological psychiatry, 12(4), 507-23. PMID: 889984

Croarkin, P., McCaffrey, P., McClintock, S., Rodez, C., & Husain, M. (2009) Electroconvulsive Therapy in Child and Adolescent Psychiatry. Current Psychiatry Reviews, 5(4), 298-305. DOI: 10.2174/157340009789542141

Greenberg RM, & Kellner CH. (2005) Electroconvulsive therapy: a selected review. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 13(4), 268-81. PMID: 15845752

Payne NA, & Prudic J. (2009) Electroconvulsive therapy: Part I. A perspective on the evolution and current practice of ECT. Journal of psychiatric practice, 15(5), 346-68. PMID: 19820553

Wachtel LE, Griffin MM, Dhossche DM, & Reti IM. (2010) Brief report: Electroconvulsive therapy for malignant catatonia in an autistic adolescent. Autism : the international journal of research and practice, 14(4), 349-58. PMID: 20591959

Wachtel LE, Jaffe R, & Kellner CH. (2011) Electroconvulsive therapy for psychotropic-refractory bipolar affective disorder and severe self-injury and aggression in an 11-year-old autistic boy. European child , 20(3), 147-52. PMID: 21249407

May 24, 2011
08:00 AM
842 views

Adventures in the Study of Altruism

by Shaheen Lakhan in Brain Blogger

Altruism is a perplexing human trait. It is a form of behavior wherein one individual assists another without an expectation of reward and sometimes even in the face of causing oneself harm. Altruism might be considered one of those traits that distinguishes human beings from animals as it appears to be almost unique to the [...]... Read more »

Koenigs, M., & Tranel, D. (2007) Irrational Economic Decision-Making after Ventromedial Prefrontal Damage: Evidence from the Ultimatum Game. Journal of Neuroscience, 27(4), 951-956. DOI: 10.1523/JNEUROSCI.4606-06.2007

Krajbich, I., Adolphs, R., Tranel, D., Denburg, N., & Camerer, C. (2009) Economic Games Quantify Diminished Sense of Guilt in Patients with Damage to the Prefrontal Cortex. Journal of Neuroscience, 29(7), 2188-2192. DOI: 10.1523/JNEUROSCI.5086-08.2009

Moll J, Krueger F, Zahn R, Pardini M, de Oliveira-Souza R, & Grafman J. (2006) Human fronto-mesolimbic networks guide decisions about charitable donation. Proceedings of the National Academy of Sciences of the United States of America, 103(42), 15623-8. PMID: 17030808

Rilling JK, & Sanfey AG. (2011) The neuroscience of social decision-making. Annual review of psychology, 23-48. PMID: 20822437

May 18, 2011
08:00 AM
1,279 views

When Dieting Interferes with Dieting

by Shaheen Lakhan in Brain Blogger

The good news is that a tendency to binge on diet-destroyers is likely to be a matter of genes. The bad news is that our brain, body and external environment can fire up this tendency making some of us more likely to binge eat than others. Dietary restraint or just plain dieting involves a conscious [...]... Read more »

Racine SE, Burt SA, Iacono WG, McGue M, & Klump KL. (2011) Dietary restraint moderates genetic risk for binge eating. Journal of abnormal psychology, 120(1), 119-28. PMID: 21171725

May 15, 2011
08:00 AM
1,137 views

Pass the Salt – Risks Linked to Low Salt Diet?

by Shaheen Lakhan in Brain Blogger

In light of the fact that approximately 90% of all Americans will develop high blood pressure during their lifetime, the American Heart Association recommends a daily intake of no more than 1,500 milligrams of sodium to reduce the risk of high blood pressure, heart attacks, stroke, and kidney disease. However, results published in the Journal [...]... Read more »

Stolarz-Skrzypek K, Kuznetsova T, Thijs L, Tikhonoff V, Seidlerová J, Richart T, Jin Y, Olszanecka A, Malyutina S, Casiglia E.... (2011) Fatal and nonfatal outcomes, incidence of hypertension, and blood pressure changes in relation to urinary sodium excretion. JAMA : the journal of the American Medical Association, 305(17), 1777-85. PMID: 21540421

Morrison AC, & Ness RB. (2011) Sodium intake and cardiovascular disease. Annual review of public health, 71-90. PMID: 21219163

Centers for Disease Control and Prevention (CDC). (2010) Sodium intake among adults - United States, 2005-2006. MMWR. Morbidity and mortality weekly report, 59(24), 746-9. PMID: 20577156

Krzesinski JM. (2009) [Sodium and arterial hypertension --one hundred years of controversies]. Bulletin et memoires de l'Academie royale de medecine de Belgique, 164(3-4), 143. PMID: 20120089

Mattes RD, & Donnelly D. (1991) Relative contributions of dietary sodium sources. Journal of the American College of Nutrition, 10(4), 383-93. PMID: 1910064

May 9, 2011
08:00 AM
1,151 views

Maternal Relationship Reduces Violence and Improves Intelligence

by Shaheen Lakhan in Brain Blogger

There is no substitute for a good mother, and a mother’s influence is one of the most powerful forces in the lives of young children. Now, research shows that a healthy, playful relationship between a child and a mother leads to adult children with higher intelligence and less involvement in violence. Beginning in the 1980s, [...]... Read more »

Walker SP, Chang SM, Powell CA, & Grantham-McGregor SM. (2005) Effects of early childhood psychosocial stimulation and nutritional supplementation on cognition and education in growth-stunted Jamaican children: prospective cohort study. Lancet, 366(9499), 1804-7. PMID: 16298218

Walker SP, Chang SM, Powell CA, Simonoff E, & Grantham-McGregor SM. (2006) Effects of psychosocial stimulation and dietary supplementation in early childhood on psychosocial functioning in late adolescence: follow-up of randomised controlled trial. BMJ (Clinical research ed.), 333(7566), 472. PMID: 16877454

Walker SP, Chang SM, Powell CA, Simonoff E, & Grantham-McGregor SM. (2007) Early childhood stunting is associated with poor psychological functioning in late adolescence and effects are reduced by psychosocial stimulation. The Journal of nutrition, 137(11), 2464-9. PMID: 17951486

Walker SP, Chang SM, Vera-Hernández M, & Grantham-McGregor S. (2011) Early childhood stimulation benefits adult competence and reduces violent behavior. Pediatrics, 127(5), 849-57. PMID: 21518715

May 3, 2011
08:00 AM
915 views

Alzheimer’s Disease and Insulin Resistance

by Shaheen Lakhan in Brain Blogger

For years, researchers have noted a connection between conditions of impaired insulin use and regulation, such as obesity and type 2 diabetes, and Alzheimer’s Disease (AD), but the mechanism of association has not been well-defined. Now, researchers report that proteins that influence the development and progression of AD are suppressed by insulin, encouraging new treatment [...]... Read more »

Biessels GJ, Kappelle LJ, & Utrecht Diabetic Encephalopathy Study Group. (2005) Increased risk of Alzheimer's disease in Type II diabetes: insulin resistance of the brain or insulin-induced amyloid pathology?. Biochemical Society transactions, 33(Pt 5), 1041-4. PMID: 16246041

Dandona P, Mohamed I, Ghanim H, Ling Sia C, Dhindsa S, Dandona S, Makdissi A, & Chaudhuri A. (2011) Insulin Suppresses the Expression of Amyloid Precursor Protein, Presenilins, and Glycogen Synthase Kinase-3{beta} in Peripheral Blood Mononuclear Cells. The Journal of clinical endocrinology and metabolism. PMID: 21411544

Maccioni RB, Muñoz JP, & Barbeito L. (2001) The molecular bases of Alzheimer's disease and other neurodegenerative disorders. Archives of medical research, 32(5), 367-81. PMID: 11578751

Naderali EK, Ratcliffe SH, & Dale MC. (2009) Obesity and Alzheimer's disease: a link between body weight and cognitive function in old age. American journal of Alzheimer's disease and other dementias, 24(6), 445-9. PMID: 19801534

Rönnemaa E, Zethelius B, Sundelöf J, Sundström J, Degerman-Gunnarsson M, Berne C, Lannfelt L, & Kilander L. (2008) Impaired insulin secretion increases the risk of Alzheimer disease. Neurology, 71(14), 1065-71. PMID: 18401020

Suh YH, & Checler F. (2002) Amyloid precursor protein, presenilins, and alpha-synuclein: molecular pathogenesis and pharmacological applications in Alzheimer's disease. Pharmacological reviews, 54(3), 469-525. PMID: 12223532

Watson GS, & Craft S. (2003) The role of insulin resistance in the pathogenesis of Alzheimer's disease: implications for treatment. CNS drugs, 17(1), 27-45. PMID: 12467491

April 30, 2011
08:33 AM
913 views

Reading between the Blogs

by Shaheen Lakhan in Brain Blogger

Blogger Lorelle VanFossen got it right when she wrote, “Your blog is your unedited version of yourself.” Personal blogs not only reveal bloggers’ opinions on assorted motley topics such as fashion, politics, TV shows, food, pop culture, subculture, whatnots, but also expose the bloggers’ psyche. Psychologists have long suspected links between language and personality, but [...]... Read more »

Yarkoni, T. (2010) Personality in 100,000 Words: A large-scale analysis of personality and word use among bloggers. Journal of Research in Personality, 44(3), 363-373. DOI: 10.1016/j.jrp.2010.04.001

April 27, 2011
08:00 AM
928 views

Self-Injury and the Internet

by Shaheen Lakhan in Brain Blogger

Deliberate nonsuicidal self-injury is the intentional harming of one’s own body, and may include cutting, burning, scratching, minor overdosing, banging, or hitting. New research finds that images and live-action videos depicting self-injury permeate the internet. The images are accessible to youth at risk for this dangerous behavior, and reinforce, glamorize, and provoke self-destructive behavior. The [...]... Read more »

Borzekowski DL, Schenk S, Wilson JL, & Peebles R. (2010) e-Ana and e-Mia: A content analysis of pro-eating disorder Web sites. American journal of public health, 100(8), 1526-34. PMID: 20558807

Jett S, LaPorte DJ, & Wanchisn J. (2010) Impact of exposure to pro-eating disorder websites on eating behaviour in college women. European eating disorders review : the journal of the Eating Disorders Association, 18(5), 410-6. PMID: 20572210

Klonsky ED, & Muehlenkamp JJ. (2007) Self-injury: a research review for the practitioner. Journal of clinical psychology, 63(11), 1045-56. PMID: 17932985

Lewis SP, Heath NL, St Denis JM, & Noble R. (2011) The scope of nonsuicidal self-injury on YouTube. Pediatrics, 127(3). PMID: 21339269

Nixon MK, Cloutier P, & Jansson SM. (2008) Nonsuicidal self-harm in youth: a population-based survey. CMAJ : Canadian Medical Association journal , 178(3), 306-12. PMID: 18227450

Tuisku V, Pelkonen M, Kiviruusu O, Karlsson L, Ruuttu T, & Marttunen M. (2009) Factors associated with deliberate self-harm behaviour among depressed adolescent outpatients. Journal of adolescence, 32(5), 1125-36. PMID: 19307015

April 24, 2011
08:00 AM
932 views

Standardized Labels to Improve Low Health Literacy

by Shaheen Lakhan in Brain Blogger

Low health literacy contributes to medication errors, noncompliance, low quality of life, and poor health outcomes. With an aging population on a never-ending stream of prescription and over-the-counter medications, the risk of confusion and misunderstanding of drug regimens is substantial. A new study published in Archives of Internal Medicine reports that most patients cannot even [...]... Read more »

Macabasco-O'Connell A, Dewalt DA, Broucksou KA, Hawk V, Baker DW, Schillinger D, Ruo B, Bibbins-Domingo K, Holmes GM, Erman B.... (2011) Relationship Between Literacy, Knowledge, Self-Care Behaviors, and Heart Failure-Related Quality of Life Among Patients With Heart Failure. Journal of general internal medicine. PMID: 21369770

Osborn CY, Paasche-Orlow MK, Bailey SC, & Wolf MS. (2011) The mechanisms linking health literacy to behavior and health status. American journal of health behavior, 35(1), 118-28. PMID: 20950164

Wolf MS, Curtis LM, Waite K, Bailey SC, Hedlund LA, Davis TC, Shrank WH, Parker RM, & Wood AJ. (2011) Helping patients simplify and safely use complex prescription regimens. Archives of internal medicine, 171(4), 300-5. PMID: 21357804

Wolf MS, Davis TC, Bass PF, Curtis LM, Lindquist LA, Webb JA, Bocchini MV, Bailey SC, & Parker RM. (2010) Improving prescription drug warnings to promote patient comprehension. Archives of internal medicine, 170(1), 50-6. PMID: 20065199

Wolf MS, Davis TC, Curtis LM, Webb JA, Bailey SC, Shrank WH, Lindquist L, Ruo B, Bocchini MV, Parker RM.... (2011) Effect of standardized, patient-centered label instructions to improve comprehension of prescription drug use. Medical care, 49(1), 96-100. PMID: 21150800

April 21, 2011
08:00 AM
772 views

Headache Treatment – Alternative or Illicit?

by Shaheen Lakhan in Brain Blogger

Headache disorders can be painful and debilitating conditions. Ranging from infrequent tension-type headaches to cluster headaches to migraines, headaches affect nearly every individual at one time or another. Pain – particularly of the neck and back – accompany many headaches. Traditional pharmacological treatment begins with acetaminophen (Tylenol), but this is not effective for all headache [...]... Read more »

Ahn CB, Lee SJ, Lee JC, Fossion JP, & Sant'ana A. (2011) A Clinical Pilot Study Comparing Traditional Acupuncture to Combined Acupuncture for Treating Headache, Trigeminal Neuralgia and Retro-auricular Pain in Facial Palsy. Journal of acupuncture and meridian studies, 4(1), 29-43. PMID: 21440878

Biondi DM. (2005) Physical treatments for headache: a structured review. Headache, 45(6), 738-46. PMID: 15953306

Biondi DM. (2005) Noninvasive treatments for headache. Expert review of neurotherapeutics, 5(3), 355-62. PMID: 15938668

Leone M, Franzini A, Cecchini AP, Mea E, Broggi G, & Bussone G. (2009) Cluster headache: pharmacological treatment and neurostimulation. Nature clinical practice. Neurology, 5(3), 153-62. PMID: 19262591

Sewell RA. (2009) Response of cluster headache to kudzu. Headache, 49(1), 98-105. PMID: 19125878

Sewell RA, Halpern JH, & Pope HG Jr. (2006) Response of cluster headache to psilocybin and LSD. Neurology, 66(12), 1920-2. PMID: 16801660

Söderberg E, Carlsson J, & Stener-Victorin E. (2006) Chronic tension-type headache treated with acupuncture, physical training and relaxation training. Between-group differences. Cephalalgia : an international journal of headache, 26(11), 1320-9. PMID: 17059439

Söderberg EI, Carlsson JY, Stener-Victorin E, & Dahlöf C. (2011) Subjective Well-being in Patients With Chronic Tension-type Headache: Effect of Acupuncture, Physical Training, and Relaxation Training. The Clinical journal of pain. PMID: 21317776

Sun-Edelstein C, & Mauskop A. (2011) Alternative headache treatments: nutraceuticals, behavioral and physical treatments. Headache, 51(3), 469-83. PMID: 21352222

April 18, 2011
08:00 AM
450 views

Mass Murderer Psychology – The Patterns of Horror

by Shaheen Lakhan in Brain Blogger

My first reaction on learning about the Realengo school shootings in Rio de Janeiro was to feel tremendous, almost physical pain at trying to imagine what could possess a man to shoot little children at random. After writing about how I felt and the implications of the event, I came across the murderer’s letter on [...]... Read more »

Knoll JL 4th. (2010) The "pseudocommando" mass murderer: part I, the psychology of revenge and obliteration. The journal of the American Academy of Psychiatry and the Law, 38(1), 87-94. PMID: 20305080

Meloy JR, Hempel AG, Mohandie K, Shiva AA, & Gray BT. (2001) Offender and offense characteristics of a nonrandom sample of adolescent mass murderers. Journal of the American Academy of Child and Adolescent Psychiatry, 40(6), 719-28. PMID: 11392351

Myers, W. (2004) Serial murder by children and adolescents. Behavioral Sciences , 22(3), 357-374. DOI: 10.1002/bsl.590

April 15, 2011
08:00 AM
1,372 views

FDA Supports Compounding of Off-Label Drug to Prevent Preterm Labor

by Shaheen Lakhan in Brain Blogger

Recently, the U.S. Food and Drug Administration (FDA) approved the new drug Makena (17-hydroxyprogesterone caproate) for the prevention of preterm labor. This is the first FDA-approved drug for this indication, but the active ingredient in the drug has been a standard of care for preventing preterm labor for nearly a decade. Until now, it has [...]... Read more »

Joy S, Rhea DJ, Istwan NB, Desch CN, & Stanziano G. (2010) The risk for preterm labor in women receiving 17 alpha-hydroxyprogesterone caproate prophylaxis for preterm birth prevention. American journal of perinatology, 27(4), 343-8. PMID: 20013580

ACOG Committee on Practice Bulletins--Obstetrics. (2003) ACOG practice bulletin. Management of preterm labor. Number 43, May 2003. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 82(1), 127-35. PMID: 12834934

Mason MV, Poole-Yaeger A, Krueger CR, House KM, & Lucas B. (2010) Impact of 17P usage on NICU admissions in a managed medicaid population--a five-year review. Managed care (Langhorne, Pa.), 19(2), 46-52. PMID: 20550052

Petrini JR, Callaghan WM, Klebanoff M, Green NS, Lackritz EM, Howse JL, Schwarz RH, & Damus K. (2005) Estimated effect of 17 alpha-hydroxyprogesterone caproate on preterm birth in the United States. Obstetrics and gynecology, 105(2), 267-72. PMID: 15684150

April 12, 2011
08:00 AM
538 views

Suicide Gene Identified

by Shaheen Lakhan in Brain Blogger

Suicidal behavior is a leading cause of death and disability in the United States. Suicide is influenced by a variety of factors, including psychological, social, moral, political, and economic influences. Heredity has also been linked to suicidal thoughts and actions. Now, new evidence suggests that suicide attempt is linked to a specific gene. In 2007, [...]... Read more »

Crosby AE, Ortega L, Stevens MR, & Centers for Disease Control and Prevention (CDC). (2011) Suicides - United States, 1999-2007. MMWR. Surveillance summaries : Morbidity and mortality weekly report. Surveillance summaries / CDC, 56-9. PMID: 21430622

Cui H, Supriyanto I, Sasada T, Shiroiwa K, Fukutake M, Shirakawa O, Asano M, Ueno Y, Nagasaki Y, & Hishimoto A. (2011) Association study of EP1 gene polymorphisms with suicide completers in the Japanese population. Progress in neuro-psychopharmacology . PMID: 21447366

Mahon PB, Stütz AM, Seifuddin F, Huo Y, Goes FS, Jancic D, Judy JT, Depaulo JR Jr, Gershon ES, McMahon FJ.... (2010) Case-control association study of TGOLN2 in attempted suicide. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 153B(5), 1016-23. PMID: 20468057

Perlis RH, Huang J, Purcell S, Fava M, Rush AJ, Sullivan PF, Hamilton SP, McMahon FJ, Schulze TG, Potash JB.... (2010) Genome-wide association study of suicide attempts in mood disorder patients. The American journal of psychiatry, 167(12), 1499-507. PMID: 21041247

Serafini G, Pompili M, Innamorati M, Giordano G, Tatarelli R, Lester D, Girardi P, & Dwivedi Y. (2011) Glycosides, depression and suicidal behaviour: the role of glycoside-linked proteins. Molecules (Basel, Switzerland), 16(3), 2688-713. PMID: 21441870

Willour VL, Seifuddin F, Mahon PB, Jancic D, Pirooznia M, Steele J, Schweizer B, Goes FS, Mondimore FM, Mackinnon DF.... (2011) A genome-wide association study of attempted suicide. Molecular psychiatry. PMID: 21423239

Willour VL, Zandi PP, Badner JA, Steele J, Miao K, Lopez V, MacKinnon DF, Mondimore FM, Schweizer B, McInnis MG.... (2007) Attempted suicide in bipolar disorder pedigrees: evidence for linkage to 2p12. Biological psychiatry, 61(5), 725-7. PMID: 17046723

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Why is this post inappropriate?

Why is this post inappropriate?

Why is this post inappropriate?

Why is this post inappropriate?

Why is this post inappropriate?

Why is this post inappropriate?

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