415 posts · 641,336 views
This is the personal blog of a Dutch psychiatrist working in a University hospital. His specialty in psychiatry is the treatment of depression. This explains his interest in electroconvulsive therapy and the development of new forms of neurostimulation for the treatment of depression. He is also involved in medical education. He does research in the treatment and neuroscience of depression. He mostly writes about these topics on this blog for fun and to keep up with recent developments. Besides writing about his work he also writes about other subjects that (neuro)stimulates him such as chocolate, computer gaming, gadgets, and Internet. The postings are based on what I want to write about and what I feel will be interesting to read.
Dr Shock MD PhD
415 posts
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- December 23, 2009
- 02:30 AM
- 1,823 views
Deep Brain Stimulation for Schizophrenia?
by Dr Shock in Dr Shock MD PhD
In short, a recent article proposed to do deep brain stimulation for schizophenia. Schizophrenia has positive-, negative- and cognitive symptoms (see the figure above). The authors propose the DBS for positive symptoms. Their approach is based on current models of the neurocircuitry of psychosis .
They hypothesize:
that chronic, high frequency electrical stimulation (HFS) of [...]
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Mikell, C., McKhann, G., Segal, S., McGovern, R., Wallenstein, M., & Moore, H. (2009) The Hippocampus and Nucleus Accumbens as Potential Therapeutic Targets for Neurosurgical Intervention in Schizophrenia. Stereotactic and Functional Neurosurgery, 87(4), 256-265. DOI: 10.1159/000225979
Bakay, R. (2009) Deep Brain Stimulation for Schizophrenia. Stereotactic and Functional Neurosurgery, 87(4), 266-266. DOI: 10.1159/000225980
- December 21, 2009
- 02:50 AM
- 1,430 views
Virtual Reality for Treatment of PTSD
by Dr Shock in Dr Shock MD PhD
Three fast track articles were recently published on CyberPsychology and Behavior about the treatment of PTSD with virtual reality exposure therapy. Exposure therapy is the most evidence based treatment for Post Traumatic Stress Disorder (PTSD). More than 18 studies have been published on the use of virtual reality exposure treatment for PTSD.
One of [...]
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McLay, R., McBrien, C., Wiederhold, M., & Wiederhold, B. (2009) Exposure Therapy with and without Virtual Reality to Treat PTSD while in the Combat Theater: A Parallel Case Series. CyberPsychology , 2147483647. DOI: 10.1089/cpb.2009.0346
Gamito, P., Oliveira, J., Rosa, P., Morais, D., Duarte, N., Oliveira, S., & Saraiva, T. (2009) PTSD Elderly War Veterans: A Clinical Controlled Pilot Study. CyberPsychology , 2147483647. DOI: 10.1089/cpb.2009.0237
Botella, C., García-Palacios, A., Guillen, V., Baños, R., Quero, S., & Alcaniz, M. (2009) An Adaptive Display for the Treatment of Diverse Trauma PTSD Victims. CyberPsychology , 2147483647. DOI: 10.1089/cpb.2009.0353
- December 16, 2009
- 05:35 AM
- 1,685 views
Personality Traits and Political Attitude
by Dr Shock in Dr Shock MD PhD
The relationship between personality and political preferences is not the simple relation between conservatism and negative personality traits on the one hand and liberalism and positive personality traits on the other hand. Personality is understood as the combination of innate dispositions and personal experiences that guides behavior in a stable and predictive manner. Behavior is [...]
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Verhulst, B., Hatemi, P., & Martin, N. (2009) The nature of the relationship between personality traits and political attitudes. Personality and Individual Differences. DOI: 10.1016/j.paid.2009.11.013
- December 15, 2009
- 02:06 AM
- 1,837 views
The Neurobiology of Love
by Dr Shock in Dr Shock MD PhD
Previously we discussed the neurobiology of falling in love. But this is only the beginning, the process of attraction followed by the attachment process. This process can develop and last for a while or in some cases for ever. Biologically is falling in love the first step in pair formation.
Falling in love is more accompanied [...]
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ZEKI, S. (2007) The neurobiology of love. FEBS Letters, 581(14), 2575-2579. DOI: 10.1016/j.febslet.2007.03.094
Esch T, & Stefano GB. (2005) The Neurobiology of Love. Neuro endocrinology letters, 26(3), 175-92. PMID: 15990719
- December 9, 2009
- 02:25 AM
- 1,679 views
Empathy for the Mentally Ill in Medical Education
by Dr Shock in Dr Shock MD PhD
Empathy is an important asset for a doctor. This ability to appreciate patients’ emotions and express this emotional awareness improves clinical outcomes, professional satisfaction, and patient adherence to medical recommendations, and is believed to significantly improve patient satisfaction. More on empathy and what it is can be read here
There is a significant decline in empathy [...]
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William Bunn, D.O. and Jan Terpstra, M.D. (2009) Cultivating Empathy for the Mentally Ill Using Simulated Auditory Hallucinations. Academic Psychiatry. DOI: 10.1176/appi.ap.33.6.457
- December 8, 2009
- 02:40 AM
- 1,434 views
Love is Great for Creativity, Sex for Analytical Thinking
by Dr Shock in Dr Shock MD PhD
Most people think that love and sex are tightly related. Nevertheless the size of the overlap between these two varies with culture, history, education and social values.
In the United States, males report having less problems imagining sex without love than females do; in China, however the link between love and romance seems to be [...]
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Forster, J., Epstude, K., & Ozelsel, A. (2009) Why Love Has Wings and Sex Has Not: How Reminders of Love and Sex Influence Creative and Analytic Thinking. Personality and Social Psychology Bulletin, 35(11), 1479-1491. DOI: 10.1177/0146167209342755
- December 1, 2009
- 01:53 AM
- 1,457 views
Searching Dating Sites Reduces Decision Quality
by Dr Shock in Dr Shock MD PhD
Dating sites as well as social networking sites have search options. In the case of dating sites were people can look for interpersonal romantic relationships these search options deliver more options to search and more possible partners. More options with searching often are accompanied by excessive searching and decreasing the quality of the choices.
In [...]
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Yang, M., & Chiou, W. (2009) Looking Online for the Best Romantic Partner Reduces Decision Quality: The Moderating Role of Choice-Making Strategies. CyberPsychology , 2147483647. DOI: 10.1089/cpb.2009.0208
- November 25, 2009
- 03:09 AM
- 1,917 views
Can MRI Scans Predict Outcome in Depression?
by Dr Shock in Dr Shock MD PhD
In a recent previous post the topic was the neuroanatomy of depression, or which sites of the brain can play a role in depression. Which parts of the brain show the dysfunction underlying depression. MRI scans can link neurobiology of depression with clinical findings through brain imaging studies that examine regional structure, regional function or [...]
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MacQueen GM. (2009) Magnetic resonance imaging and prediction of outcome in patients with major depressive disorder. Journal of psychiatry , 34(5), 343-9. PMID: 19721844
- November 23, 2009
- 02:39 AM
- 1,963 views
The Functional Neuroanatomy of Depression
by Dr Shock in Dr Shock MD PhD
Based on the results from functional neuroimaging studies, lesion patient studies and brain stimulation studies two important brain areas play an important role in the pathophysiology of depression. These two brain area s are the ventromedial prefrontal cortex and the dorsolateral prefrontal cortex. The ventromedial prefrontal cortex is depicted in red on the picture above [...]
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Koenigs, M., & Grafman, J. (2009) The functional neuroanatomy of depression: Distinct roles for ventromedial and dorsolateral prefrontal cortex. Behavioural Brain Research, 201(2), 239-243. DOI: 10.1016/j.bbr.2009.03.004
Lui, S., Parkes, L., Huang, X., Zou, K., Chan, R., Yang, H., Zou, L., Li, D., Tang, H., Zhang, T.... (2009) Depressive Disorders: Focally Altered Cerebral Perfusion Measured with Arterial Spin-labeling MR Imaging. Radiology, 251(2), 476-484. DOI: 10.1148/radiol.2512081548
Costafreda, S., Chu, C., Ashburner, J., & Fu, C. (2009) Prognostic and Diagnostic Potential of the Structural Neuroanatomy of Depression. PLoS ONE, 4(7). DOI: 10.1371/journal.pone.0006353
- November 19, 2009
- 02:22 AM
- 2,529 views
Lying on Adolescents’ Blogs
by Dr Shock in Dr Shock MD PhD
Adolescents are the most truthful about school and their life on blogs, whereas they are the least truthful about intimate topics such as family life and partnership. Adolescents present their personal information on blogs very truthfully. A girls of fourteen is really a girl of fourteen.
During adolescence forming an identity is a key developmental task [...]
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Blinka, L., & Smahel, D. (2009) Fourteen Is Fourteen and a Girl Is a Girl: Validating the Identity of Adolescent Bloggers. CyberPsychology , 2147483647. DOI: 10.1089/cpb.2009.0044
- November 18, 2009
- 03:11 AM
- 2,022 views
Self Diagnosis in General Practice
by Dr Shock in Dr Shock MD PhD
With the Internet many patients visit the GP after extensive searches on the Internet. They usually have an idea about what’s wrong with them. In a recent publication in the British Medical Journal I found a recent article on this subject. In visits to a GP patients the self diagnosis (also called self labelling) was [...]
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Goyder, C., McPherson, A., & Glasziou, P. (2009) Self diagnosis. BMJ, 339(nov11 1). DOI: 10.1136/bmj.b4418
- November 17, 2009
- 02:29 AM
- 1,818 views
Chocolate Craving and the Menstrual Cycle
by Dr Shock in Dr Shock MD PhD
About chocolate craving:
Research suggests that up to 97% of women and 68% of men experience food cravings. Chocolate is the most common one of the craved foods, typically high calorie.
A number of situations have been shown to experimentally increase cravings of chocolate consumption. For example,chocolate abstinence, stress and exposure to chocolate cues increase urges to [...]
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Hormes, J., & Rozin, P. (2009) Perimenstrual chocolate craving. What happens after menopause?. Appetite, 53(2), 256-259. DOI: 10.1016/j.appet.2009.07.003
- November 16, 2009
- 02:35 AM
- 1,621 views
The Neuroscience of Music Enjoyment and Depression
by Dr Shock in Dr Shock MD PhD
When feeling down good music can cheer you up. But when depressed, I mean clinically depressed, can you enjoy music? How is music enjoyment processed by the brain and how is this influenced by depression?
All participants of this study enjoyed their favorite music more than the neutral music and depressed patients didn’t differ from the [...]
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Osuch, E., Bluhm, R., Williamson, P., Théberge, J., Densmore, M., & Neufeld, R. (2009) Brain activation to favorite music in healthy controls and depressed patients. NeuroReport, 20(13), 1204-1208. DOI: 10.1097/WNR.0b013e32832f4da3
- November 9, 2009
- 03:14 AM
- 1,805 views
Music Preference and Substance Use
by Dr Shock in Dr Shock MD PhD
From a large Dutch epidemiological study: overall, when all other factors were controlled, punk/hardcore, techno/hardhouse, and reggae were associated with more substance use, while pop and classical music marked less substance use. In contrast to previous research heavy metal and rap/hip-hop, were not of marked importance here.
Music in the life of an adolescent is very [...]
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Mulder, J., Ter Bogt, T., Raaijmakers, Q., Gabhainn, S., Monshouwer, K., & Vollebergh, W. (2009) The Soundtrack of Substance Use: Music Preference and Adolescent Smoking and Drinking. Substance Use , 44(4), 514-531. DOI: 10.1080/10826080802347537
- November 6, 2009
- 02:27 AM
- 1,734 views
Blog writing for professionalism in medical education
by Dr Shock in Dr Shock MD PhD
Had an idea to use writing of a blog for a minor in medical education. The idea was sacrificed for other options for minors. Seems that blogs in medical education can promote reflection and professionalism. Professionalism being one of the CanMed competences used in medical education and one of the most important ones not easily [...]
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Chretien, K., Goldman, E., & Faselis, C. (2008) The Reflective Writing Class Blog: Using Technology to Promote Reflection and Professional Development. Journal of General Internal Medicine, 23(12), 2066-2070. DOI: 10.1007/s11606-008-0796-5
- November 4, 2009
- 02:41 AM
- 1,484 views
Insomnia and Depression
by Dr Shock in Dr Shock MD PhD
patients with depression often complain of difficulty getting to sleep, frequent awakenings during the night, early morning awakening, or nonrestorative sleep
patients with mood disorders exhibit higher rates of sleep disturbance than the general population, and sleep disturbance can continue even during periods of remission
patients with insomnia are up to 10 times more likely to have [...]
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BENCA, R., & PETERSON, M. (2008) Insomnia and depression. Sleep Medicine. DOI: 10.1016/S1389-9457(08)70010-8
Holshoe, J. (2009) Antidepressants and Sleep: A Review. Perspectives in Psychiatric Care, 45(3), 191-197. DOI: 10.1111/j.1744-6163.2009.00221.x
- November 3, 2009
- 02:39 AM
- 1,690 views
Sleep Changes with Aging
by Dr Shock in Dr Shock MD PhD
Aging is associated with well described changing in sleep patterns.
Total sleep time decreases, elderly sleep less
It takes longer before falling a sleep
Elderly go to bed earlier and they awake earlier
There sleep architecture has changed, the slow wave sleep on EEG is reduced, REM sleep is reduced
They’re easier aroused from sleep
They sleep fragmented with many arousals
Daytime [...]
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Wolkove, N., Elkholy, O., Baltzan, M., & Palayew, M. (2007) Sleep and aging: 1. Sleep disorders commonly found in older people. Canadian Medical Association Journal, 176(9), 1299-1304. DOI: 10.1503/cmaj.060792
Wolkove, N., Elkholy, O., Baltzan, M., & Palayew, M. (2007) Sleep and aging: 2. Management of sleep disorders in older people. Canadian Medical Association Journal, 176(10), 1449-1454. DOI: 10.1503/cmaj.070335
- November 2, 2009
- 02:27 AM
- 1,658 views
Exercise and Mental Health
by Dr Shock in Dr Shock MD PhD
A recent review about the relationship between exercise and mental health in the elderly discussed the results of clinical research and biological explanations for the effects of exercise on mental health. Exercise is studied in the elderly in depression, Alzheimer’s disease and Parkinson’s disease.
We’ve discussed the topic of exercise and depression before on this blog. [...]
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Deslandes, A., Moraes, H., Ferreira, C., Veiga, H., Silveira, H., Mouta, R., Pompeu, F., Coutinho, E., & Laks, J. (2009) Exercise and Mental Health: Many Reasons to Move. Neuropsychobiology, 59(4), 191-198. DOI: 10.1159/000223730
- October 27, 2009
- 03:37 AM
- 1,072 views
Medical Education Evaluated With Twitter
by Dr Shock in Dr Shock MD PhD
The course in their third year of med school about the Brains and the Sensory system in which psychiatry participates is a course of at least three months. It’s made of different sub courses which each take about 3 to 4 weeks. These courses are evaluated at the end. That’s to say months after the [...]
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Stieger, S., & Burger, C. (2009) Let's Go Formative: Continuous Student Ratings with Web 2.0 Application Twitter. CyberPsychology , 2147483647. DOI: 10.1089/cpb.2009.0128
- October 21, 2009
- 02:39 AM
- 1,820 views
Conflicts of Interest in Medical Journal Publishing
by Dr Shock in Dr Shock MD PhD
Publish or Perish sums up the urgency for scientists to publish in top journals. Scientists work in competitive environments in which publishing is essential to their careers, reputation and research funding. Journal editors and peer reviewers are the ones to judge the manuscripts for quality and safeguard the interests of the readership of the journal.
The [...]
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Drazen, J., Van Der Weyden, M., Sahni, P., Rosenberg, J., Marusic, A., Laine, C., Kotzin, S., Horton, R., Hebert, P., Haug, C.... (2009) Uniform Format for Disclosure of Competing Interests in ICMJE Journals. New England Journal of Medicine. DOI: 10.1056/nejme0909052
Jefferson, T. (2002) Effects of Editorial Peer Review: A Systematic Review. JAMA: The Journal of the American Medical Association, 287(21), 2784-2786. DOI: 10.1001/jama.287.21.2784
DeMaria, A. (2003) Duplicate publication: insights into the essence of a medical journal. Journal of the American College of Cardiology, 41(3), 516-517. DOI: 10.1016/S0735-1097(03)00002-0
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