Scott Gavura , Scott , Scott Gavura

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  • August 1, 2011
  • 09:18 AM
  • 1,975 views

Salt: More confirmation bias for your preferred narrative

by Scott in Science-Based Pharmacy

Judging by the recent press reports, the latest Cochrane review reveals that everything we’ve been told about eating salt, and cardiovascular disease, is wrong: The New York Times: Nostrums: Cutting Salt Has Little Effect on Heart Risk The Daily Mail: Cutting back on salt ‘does not make you healthier’ (despite nanny state warnings) Scientific American: [...]... Read more »

  • July 21, 2011
  • 09:00 AM
  • 2,095 views

Salt: More confirmation bias for your preferred narrative

by Scott Gavura in Science-Based Medicine

Judging by the recent press reports, the latest Cochrane review reveals that everything we’ve been told about eating salt, and cardiovascular disease, is wrong: The New York Times: Nostrums: Cutting Salt Has Little Effect on Heart Risk The Daily Mail: Cutting back on salt ‘does not make you healthier’ (despite nanny state warnings) Scientific American: [...]... Read more »

Taylor RS, Ashton KE, Moxham T, Hooper L, & Ebrahim S. (2011) Reduced dietary salt for the prevention of cardiovascular disease. Cochrane database of systematic reviews (Online). PMID: 21735439  

  • July 10, 2011
  • 06:38 PM
  • 2,165 views

Vaccine Confidence: Attitudes and Actions

by Scott in Science-Based Pharmacy

Few groups are more hazardous to public health than the anti-vaccine movement — because there’s a body count affiliated with their actions. When vaccination rates drop, communicable diseases re-emerge, and people suffer. While anti-vaccine sentiment will probably persist as long as vaccines are around, we’re fortunate that vaccination rates, on balance, remain very high. In [...]... Read more »

Kennedy A, Lavail K, Nowak G, Basket M, & Landry S. (2011) Confidence about vaccines in the United States: understanding parents' perceptions. Health affairs (Project Hope), 30(6), 1151-9. PMID: 21653969  

  • July 7, 2011
  • 09:00 AM
  • 1,840 views

Vaccine Confidence: Attitudes and Actions

by Scott Gavura in Science-Based Medicine

Few groups are more hazardous to public health than the anti-vaccine movement – because there’s a body count affiliated with their actions. When vaccination rates drop, communicable diseases re-emerge, and people suffer. While anti-vaccine sentiment will probably persist as long as vaccines are around, we’re fortunate that vaccination rates, on balance, remain very high. In [...]... Read more »

Kennedy A, Lavail K, Nowak G, Basket M, & Landry S. (2011) Confidence about vaccines in the United States: understanding parents' perceptions. Health affairs (Project Hope), 30(6), 1151-9. PMID: 21653969  

  • June 23, 2011
  • 09:13 PM
  • 1,828 views

Making sense of biomarker research

by Scott in Science-Based Pharmacy

Everything you know may be wrong. Well, not really, but reading the research of John Ioannidis does make you wonder. His work, concentrated on research about research, is popular among those that want to improve the way we deliver medicine. And that’s because he’s focused on improving the way evidence is brought to bear on [...]... Read more »

  • June 23, 2011
  • 08:30 AM
  • 1,989 views

Et tu, Biomarkers?

by Scott Gavura in Science-Based Medicine

Everything you know may be wrong. Well, not really, but reading the research of John Ioannidis does make you wonder. His work, concentrated on research about research, is a popular topic here at SBM.  And that’s because he’s focused on improving the way evidence is brought to bear on decision-making. His most famous papers get [...]... Read more »

  • June 9, 2011
  • 07:49 PM
  • 1,655 views

Placebos as Medicine: The Ethics of Homeopathy

by Scott in Science-Based Pharmacy

Is it ever ethical to provide a placebo treatment? What about when that placebo is homeopathy? Last month at Science-Based Medicine I blogged about the frequency of placebo prescribing by physicians. I admitted my personal discomfort, stating I’d refuse to dispense any prescription that would require me to deceive the patient. The discussion continued in [...]... Read more »

  • May 14, 2011
  • 03:20 PM
  • 2,008 views

Counting the Placebo Prescriptions

by Scott in Science-Based Pharmacy

How frequently are placebos prescribed and dispensed? I blogged earlier this week about Tom Blackwell’s recent article in the National Post on the prevalence of placebo prescriptions. The authors of the paper Blackwell summarized suggest that one in five physicians actively use placebos. Even if they’re being used sporadically, that’s a lot more use than [...]... Read more »

  • May 12, 2011
  • 09:00 AM
  • 2,099 views

Placebo Prescriptions

by Scott Gavura in Science-Based Medicine

Whether it’s acupuncture, homeopathy or the latest supplement, placebo effects can be difficult to distinguish from real effects. Today’s post sets aside the challenge of identifying placebo effects and look at how placebos are used in routine medical practice.  I’ve been a pharmacist for almost 20 years, and have never seen a placebo in practice, [...]... Read more »

  • April 28, 2011
  • 11:00 PM
  • 2,085 views

Do Calcium Supplements Cause Heart Attacks?

by Scott in Science-Based Pharmacy

Calcium is good for us, right? Milk products are great sources of calcium, and we’re told to emphasize milk products in our diets. Don’t (or can’t) eat enough dairy? Calcium supplements are very popular, especially among women seeking to minimize their risk of osteoporosis. Osteoporosis prevention and treatment guidelines recommend calcium and vitamin D as [...]... Read more »

  • April 28, 2011
  • 09:00 AM
  • 2,318 views

Do calcium supplements cause heart attacks?

by Scott Gavura in Science-Based Medicine

Calcium is good for us, right? Milk products are great sources of calcium, and we’re told to emphasize milk products in our diets. Don’t (or can’t) eat enough dairy? Calcium supplements are very popular, especially among women seeking to minimize their risk of osteoporosis. Osteoporosis prevention and treatment guidelines recommend calcium and vitamin D as [...]... Read more »

  • March 3, 2011
  • 09:00 AM
  • 2,011 views

Topical NSAIDs

by Scott in Science-Based Pharmacy

I have a mental basket of drugs that I suspect may be placebos. In that basket were the topical versions of non-steroidal anti-inflammatory drugs (NSAIDs). When the first products were commercially marketed over a decade ago, I found the clinical evidence unconvincing, and I suspected that the modestly positive effects were probably due to simply [...]... Read more »

Haroutiunian, S., Drennan, D., & Lipman, A. (2010) Topical NSAID Therapy for Musculoskeletal Pain. Pain Medicine, 11(4), 535-549. DOI: 10.1111/j.1526-4637.2010.00809.x  

Trelle S, Reichenbach S, Wandel S, Hildebrand P, Tschannen B, Villiger PM, Egger M, & Jüni P. (2011) Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis. BMJ (Clinical research ed.). PMID: 21224324  

  • March 3, 2011
  • 08:30 AM
  • 3,232 views

Topical NSAIDs

by Scott Gavura in Science-Based Medicine

I have a mental basket of drugs that I suspect may be placebos. In that basket were the topical versions of non-steroidal anti-inflammatory drugs (NSAIDs). When the first products were commercially marketed over a decade ago, I found the clinical evidence unconvincing, and I suspected that the modestly positive effects were probably due to simply [...]... Read more »

Massey T, Derry S, Moore RA, & McQuay HJ. (2010) Topical NSAIDs for acute pain in adults. Cochrane database of systematic reviews (Online). PMID: 20556778  

Trelle, S., Reichenbach, S., Wandel, S., Hildebrand, P., Tschannen, B., Villiger, P., Egger, M., & Juni, P. (2011) Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis. BMJ, 342(jan11 1). DOI: 10.1136/bmj.c7086  

Haroutiunian, S., Drennan, D., & Lipman, A. (2010) Topical NSAID Therapy for Musculoskeletal Pain. Pain Medicine, 11(4), 535-549. DOI: 10.1111/j.1526-4637.2010.00809.x  

  • February 17, 2011
  • 10:00 AM
  • 2,756 views

Are you sure you’re allergic to penicillin?

by Scott in Science-Based Pharmacy

As a pharmacist, when I dispense medication, it’s my responsibility to ensure that the medication is safe and appropriate for the patient. There are numerous checks we go through including verifying the dose, ensuring there are no interactions with other drugs, and verifying the patient has no history of allergy to the product prescribed. Asking [...]... Read more »

Caubet JC, Kaiser L, Lemaître B, Fellay B, Gervaix A, & Eigenmann PA. (2011) The role of penicillin in benign skin rashes in childhood: a prospective study based on drug rechallenge. The Journal of allergy and clinical immunology, 127(1), 218-22. PMID: 21035175  

  • February 17, 2011
  • 09:00 AM
  • 4,119 views

Are you sure you’re allergic to penicillin?

by Scott Gavura in Science-Based Medicine

As a pharmacist, when I dispense medication, it’s my responsibility to ensure that the medication is safe and appropriate for the patient. There are numerous checks we go through including verifying the dose, ensuring there are no interactions with other drugs, and verifying the patient has no history of allergy to the product prescribed. Asking [...]... Read more »

Caubet JC, Kaiser L, Lemaître B, Fellay B, Gervaix A, & Eigenmann PA. (2011) The role of penicillin in benign skin rashes in childhood: a prospective study based on drug rechallenge. The Journal of allergy and clinical immunology, 127(1), 218-22. PMID: 21035175  

  • February 1, 2011
  • 12:59 AM
  • 1,670 views

Celebrating Two Years of SBP

by Scott in Science-Based Pharmacy

Science-Based Pharmacy hits its second birthday today.  Two years ago it started with this post on homeopathy, which I recognized as the most ludicrous “health” product I’d ever seen sold in a pharmacy, and one I felt seriously compromised the credibility of the pharmacy profession.  That assessment still stands. After two years, homeopathy remains as [...]... Read more »

Clauson KA, Ekins J, & Goncz CE. (2010) Use of blogs by pharmacists. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 67(23), 2043-8. PMID: 21098377  

  • January 20, 2011
  • 09:00 AM
  • 1,794 views

The risks of CAM: How much do we know?

by Scott in Science-Based Pharmacy

Working in pharmacies where supplements are sold alongside traditional (over-the-counter) medications, I’m regularly astonished at the different perceptions consumers can have about the relative efficacy and safety of different types of products. Once, speaking with a customer about a medical condition she wanted to treat, I indicated that there were no effective non-prescription therapies — [...]... Read more »

  • January 20, 2011
  • 08:45 AM
  • 2,135 views

The risks of CAM: How much do we know?

by Scott Gavura in Science-Based Medicine

Working in pharmacies where supplements are sold alongside traditional (over-the-counter) medications, I’m regularly astonished at the different perceptions consumers can have about the relative efficacy and safety of different types of products. Once, speaking with a customer about a medical condition she wanted to treat, I indicated that there were no effective non-prescription therapies — [...]... Read more »

  • January 6, 2011
  • 09:00 AM
  • 2,190 views

Energy Drinks

by Scott in Science-Based Pharmacy

My stimulant of choice is coffee. I started drinking it in first-year university, and never looked back. A tiny four-cup coffee maker became my reliable companion right through graduate school. But since I stopped needing to drink a pot at a time, an entirely new category of products has appeared — the energy drink. Targeting [...]... Read more »

  • January 6, 2011
  • 07:00 AM
  • 2,880 views

Energy Drinks

by Scott Gavura in Science-Based Medicine

My stimulant of choice is coffee. I started drinking it in first-year university, and never looked back. A tiny four-cup coffee maker became my reliable companion right through graduate school. But since I stopped needing to drink a pot at a time, an entirely new category of products has appeared — the energy drink. Targeting [...]... Read more »

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