Be the highlight of Thanksgiving dinner conversation after you learn these fascinating facts about turkeys!... Read more »
Russo, E., Scicchitano, F., Citraro, R., Aiello, R., Camastra, C., Mainardi, P., Chimirri, S., Perucca, E., Donato, G., & De Sarro, G. (2012) Protective activity of α-lactoalbumin (ALAC), a whey protein rich in tryptophan, in rodent models of epileptogenesis. Neuroscience, 282-288. DOI: 10.1016/j.neuroscience.2012.09.021
Bruce KR, Steiger H, Young SN, Kin NM, Israël M, & Lévesque M. (2009) Impact of acute tryptophan depletion on mood and eating-related urges in bulimic and nonbulimic women. Journal of psychiatry , 34(5), 376-82. PMID: 19721848
Chocolate agar refers to two very different foods, only one of which actually contains chocolate. Both are prepared using agar, a mixture obtained by boiling certain types of algae to release a sugar called agarose that forms a gel when it cools. Thus agar (also called agar agar) can be used to make jelly desserts, flavours of which include coffee-coconut and, you guessed it, chocolate. It's basically a vegan form of Jell-O (which contains gelatin derived from animal bits).The second type of cho........ Read more »
Stephens D. (2009) Biology and pathogenesis of the evolutionarily successful, obligate human bacterium Neisseria meningitidis. Vaccine, 27(Suppl 2). DOI: 10.1016/j.vaccine.2009.04.070
MedicalResearch.com Interview with: Isaac Yi Kim, MD, PhD Acting Chief and Associate Professor, Division of Urology Rutgers Robert Wood Johnson Medical School Chief, Section of Urologic Oncology and Young Suk “Joseph” Kwon, MD Post-doctoral fellow Section of Urologic Oncology Rutgers Cancer … Continue reading →
The post Can Active Surveillance Be Extended To Some Men With Elevated PSAs? appeared first on MedicalResearch.com.
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Isaac Yi Kim, MD, PhD, & Young Suk "Joseph" Kwon,. (2015) Can Active Surveillance Be Extended To Some Men With Elevated PSAs?. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Karina Birgitta Berg MD Department of Ophthalmology Oslo University Hospital Oslo, Norway Medical Research: What is the background for this study? What are the main findings? Dr. Berg: Neovascular age-related macular degeneration (nAMD) has been the leading … Continue reading →
The post LUCAS: Lucentis Compared to Avastin Treat and Extend Study For Macular Degeneration appeared first on MedicalResearch.com.
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Karina Birgitta Berg MD. (2015) LUCAS: Lucentis Compared to Avastin Treat and Extend Study For Macular Degeneration. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Arri Coomarasamy, MBChB, MD, FRCOG Professor of Gynaecology and Reproductive Medicine University of Birmingham Medical Research: What is the background for this study? What are the main findings? Professor Coomarasamy: Progesterone is a natural hormone that is essential to … Continue reading →
The post Progesterone In Early Pregnancy Not Effective in Preventing Miscarriage appeared first on MedicalResearch.com.
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Arri Coomarasamy, MBChB, MD, FRCOG. (2015) Progesterone In Early Pregnancy Not Effective in Preventing Miscarriage. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Dr. Andrew Whittle, joint first-author of the paper and a postdoc in the Prof. Vidal-Puig’s lab at the time the research was conducted. Medical Research: What is the background for this study? Dr. Whittle: Antonio Vidal-Puig heads … Continue reading →
The post Circulating Protein Helps Fat Cells Resist Weight Loss appeared first on MedicalResearch.com.
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Dr. Andrew Whittle. (2015) Circulating Protein Helps Fat Cells Resist Weight Loss. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Dr. Ole Jakob Storebø Region Zealand, Child and Adolescent Psychiatric Department, Roskilde Region Zealand Psychiatry Psychiatric Research Unit, Slagelse University of Southern Denmark Department of Psychology Faculty of Health Science, Odense Denmark Medical Research: What is the background for … Continue reading →
The post Cochrane Analysis Reviews Studies of Ritalin For ADHD appeared first on MedicalResearch.com.
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Dr. Ole Jakob Storebø. (2015) Cochrane Analysis Reviews Studies of Ritalin For ADHD. MedicalResearch.com. info:/
Around the world many health services are moving towards generic (non-branded) medicines as a way to reduce costs. Where does psychology come into this? Well, we know that, thanks to the placebo effect, people's expectations about a treatment can influence the effects that treatment has on them. We also know, thanks to research conducted over the last decade, that people expect branded medicines to be more effective and to have fewer side effects than their generic counterparts. A new study in H........ Read more »
Faasse, K., Martin, L., Grey, A., Gamble, G., & Petrie, K. (2015) Impact of Brand or Generic Labeling on Medication Effectiveness and Side Effects. Health Psychology. DOI: 10.1037/hea0000282
For anyone that has followed this blog down the years you'll probably have noticed that I'm quite a big fan of the inclusion of the science of metabolomics on to the autism research menu (see here for example).Looking at the myriad of chemical footprints left behind by an almost incomprehensible number of cellular processes, metabolomics offers some real promise to autism in terms of teasing apart phenotypes and as a valuable partner to other -omics sciences in ascertaining the relevance or not ........ Read more »
Dieme B, Mavel S, Blasco H, Tripi G, Bonnet-Brilhault F, Malvy J, Bocca C, Andres CR, Nadal-Desbarats L, & Emond P. (2015) Metabolomics study of urine in autism spectrum disorders using a multiplatform analytical methodology. Journal of proteome research. PMID: 26538324
Nearly 37 million people worldwide are living with HIV. When the virus destroys so many immune cells that the body can’t fight off infection, AIDS will develop. The disease took the lives of more than a million people last year.... Read more »
Lu, M., Hou, G., Zhang, H., Suiter, C., Ahn, J., Byeon, I., Perilla, J., Langmead, C., Hung, I., Gor'kov, P.... (2015) Dynamic allostery governs cyclophilin A–HIV capsid interplay. Proceedings of the National Academy of Sciences, 201516920. DOI: 10.1073/pnas.1516920112
MedicalResearch.com Interview with: Anup Das Medical Scientist Training Program Department of Health Management and Policy University of Michigan, Ann Arbor Medical Research: What is the background for this study? What are the main findings? Response: The Centers for Medicare & … Continue reading →
The post Skilled Nursing and Readmissions Drive Up Post Hospital Discharge Spending appeared first on MedicalResearch.com.
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Anup Das. (2015) Skilled Nursing and Readmissions Drive Up Post Hospital Discharge Spending. MedicalResearch.com. info:/
MedicalResearch.com Interview Grant S Schulert MD, PhD Clinical Fellow, Division of Rheumatology Cincinnati Childrens Hospital Medical Research: What is the background for this study? What are the main findings? Dr. Schulert: Influenza infection causes millions of illnesses annually, but most of … Continue reading →
The post Genetic Links To Fatal Inflammatory Flu Reaction Discovered appeared first on MedicalResearch.com.
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Grant S Schubert MD, PhD. (2015) Genetic Links To Fatal Inflammatory Flu Reaction Discovered. MedicalResearch.com. info:/
The peer review of research proposals (grants) aims to judge the merit of projects and researchers and enable the best to be contemplated. The director of an institution in the United Kingdom shared on Twitter his struggle in evaluating the numerous proposals received and started a discussion forum from which ideas and suggestions emerged. … Read More →... Read more »
MedicalResearch.com Interview with: Dr. Ffion C Davies Consultant in Emergency Medicine & Paediatric Lead University Hospitals of Leicester NHS Trust Leicester Royal Infirmary Leicester UK Medical Research: What is the background for this study? Dr. Davies: This study is from … Continue reading →
The post Young Children Most Likely To Severe Injury and Death From Abuse appeared first on MedicalResearch.com.
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Dr. Ffion C Davies. (2015) Young Children Most Likely To Severe Injury and Death From Abuse. MedicalResearch.com. info:/
This is not a study that has a valid control group to determine if there is any benefit from ventilation. There is no group that does not receive ventilations, so it is like a study of one type of blood-letting vs. another type of blood-letting with the researchers taking for granted that blood-letting does improve outcomes. That is not a problem if blood-letting actually improves outcomes.
Should we take it for granted that blood-letting improves outcomes and that the only hypothesis worth s........ Read more »
Nichol, G., Leroux, B., Wang, H., Callaway, C., Sopko, G., Weisfeldt, M., Stiell, I., Morrison, L., Aufderheide, T., Cheskes, S.... (2015) Trial of Continuous or Interrupted Chest Compressions during CPR. New England Journal of Medicine, 2147483647. DOI: 10.1056/NEJMoa1509139
Alldredge BK,, Gelb AM,, Isaacs SM,, Corry MD,, Allen F,, Ulrich S,, Gottwald MD,, O’Neil N,, Neuhaus JM,, Segal MR,.... (2001) A Comparison of Lorazepam, Diazepam, and Placebo for the Treatment of Out-of-Hospital Status Epilepticus. New England Journal of Medicine, 345(25), 1860-1860. DOI: 10.1056/NEJM200112203452521
MedicalResearch.com Interview with: Dr. William H. Shrank, MD, MSHS Senior Vice President, Chief Scientific Officer and Chief Medical Officer Provider Innovation and Analytics CVS Health Medical Research: What is the background for this study? Dr. Shrank: CVS Health launched, a … Continue reading →
The post Prescription ReadyFill® Program Improved Medication Adherence and Reduced Waste appeared first on MedicalResearch.com.
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Dr. William H. Shrank, MD, MSHS. (2015) Prescription ReadyFill® Program Improved Medication Adherence and Reduced Waste. MedicalResearch.com. info:/
Usually for Thanksgiving week posting is light. In the past, we’ve all done turkey breeding and genomics, cranberry genome, and some people have included apples, potatoes, and more. But another key aspect of the holiday is to remember the past and thank those who came before. And as I was watching this video that crossed my […]... Read more »
Nelson, G., Sweeney, P., Wallace, L., Rabeler, R., Allard, D., Brown, H., Carter, J., Denslow, M., Ellwood, E., Germain-Aubrey, C.... (2015) Digitization Workflows for Flat Sheets and Packets of Plants, Algae, and Fungi. Applications in Plant Sciences, 3(9), 1500065. DOI: 10.3732/apps.1500065
Nelson, G., Paul, D., Riccardi, G., & Mast, A. (2012) Five task clusters that enable efficient and effective digitization of biological collections. ZooKeys, 19-45. DOI: 10.3897/zookeys.209.3135
Jolley-Rogers, G., Varghese, T., Harvey, P., dos Remedios, N., & Miller, J. (2014) PhyloJIVE: Integrating biodiversity data with the Tree of Life. Bioinformatics, 30(9), 1308-1309. DOI: 10.1093/bioinformatics/btu024
by Rita Handrich in The Jury Room
The growing body of research on genetic variations and their relation to crime may leave you uncertain about how to best defend your client charged with a violent crime. Do you encourage jurors to support an insanity defense by using a genetic defense or does that route backfire and leave jurors seeing your client as […]
Teaching people about neuroscience can make them softer on crime!
The “Nerd Defense”: Redux
Automatism and the Ambien Defense
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Cheung BY, & Heine SJ. (2015) The Double-Edged Sword of Genetic Accounts of Criminality: Causal Attributions From Genetic Ascriptions Affect Legal Decision Making. Personality . PMID: 26498975
This is a post written jointly by Nelson Lau from Brandeis and me, Björn Brembs. In contrast to Nelson’s guest post, which focused on the open data aspect of our collaboration, this one describes the science behind our paper and […] ↓ Read the rest of this entry...... Read more »
Rahman R, Chirn GW, Kanodia A, Sytnikova YA, Brembs B, Bergman CM, & Lau NC. (2015) Unique transposon landscapes are pervasive across Drosophila melanogaster genomes. Nucleic acids research. PMID: 26578579
Chirn, G., Rahman, R., Sytnikova, Y., Matts, J., Zeng, M., Gerlach, D., Yu, M., Berger, B., Naramura, M., Kile, B.... (2015) Conserved piRNA Expression from a Distinct Set of piRNA Cluster Loci in Eutherian Mammals. PLOS Genetics, 11(11). DOI: 10.1371/journal.pgen.1005652
"Are you on the autistic spectrum? Take the test" read a recent media headline.Commenting on the findings reported by Emily Ruzich and colleagues , the headline is followed by some pretty bizarre text about how the study "has confirmed that men are more likely to be autistic than women."I have to take some exception to this sentence, as I quote from the Ruzich findings: "In a sample of nearly half a million individuals, we found a moderate effect of sex on AQ [Autism-Spectrum Quotie........ Read more »
Westwood, H., Eisler, I., Mandy, W., Leppanen, J., Treasure, J., & Tchanturia, K. (2015) Using the Autism-Spectrum Quotient to Measure Autistic Traits in Anorexia Nervosa: A Systematic Review and Meta-Analysis. Journal of Autism and Developmental Disorders. DOI: 10.1007/s10803-015-2641-0
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