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Amasian Science
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- April 3, 2012
- 04:02 PM
- 546 views
A man, a mouse, and a fruit fly walk into a bar: Genetic approaches in understanding Alcohol Use Disorder (AUD)
by Viet Le in Amasian Science
The recent buzz surrounding the drinking habits of Drosophila, from dealing with rejection to killing parasites by self-medicating, got me thinking: How might fruit flies be used for research in understanding the cause of alcohol use disorder (AUD)? AUD, which encompasses both alcohol abuse and dependency, affects millions of Americans and is a complex disorder influenced … Continue reading »... Read more »
Joslyn, G., Wolf, F., Brush, G., Wu, L., Schuckit, M., White, R., & Hall, I. (2011) Glypican Gene GPC5 Participates in the Behavioral Response to Ethanol: Evidence from Humans, Mice, and Fruit Flies. G3: Genes|Genomes|Genetics, 1(7), 627-635. DOI: 10.1534/g3.111.000976
- April 23, 2012
- 05:41 PM
- 492 views
Condemned to a Skeletal Prison
by Viet Le in Amasian Science
Imagine going to sleep and waking up the next morning not able to bend your elbow or knee. Or imagine having difficulty drawing breath because your rib cage is starting to fuse. Imagine being unable to enjoy your favorite cut of steak because your jaw has locked into place. Even worse, imagine having … Continue reading »... Read more »
Chakkalakal, S., Zhang, D., Culbert, A., Convente, M., Caron, R., Wright, A., Maidment, A., Kaplan, F., & Shore, E. (2012) An Acvr1 R206H knock-in mouse has fibrodysplasia ossificans progressiva. Journal of Bone and Mineral Research. DOI: 10.1002/jbmr.1637
- November 30, 1999
- 12:00 AM
- 463 views
Pink Slime: My beef with Jamie Oliver and Food Blogs
by Viet Le in Amasian Science
Examining the importance of accurate representations of science in food safety.... Read more »
O'Brien, A., Newland, J., Miller, S., Holmes, R., Smith, H., & Formal, S. (1984) Shiga-like toxin-converting phages from Escherichia coli strains that cause hemorrhagic colitis or infantile diarrhea. Science, 226(4675), 694-696. DOI: 10.1126/science.6387911
Perna, N., Plunkett, G., Burland, V., Mau, B., Glasner, J., Rose, D., Mayhew, G., Evans, P., Gregor, J., Kirkpatrick, H.... (2001) Genome sequence of enterohaemorrhagic Escherichia coli O157:H7. Nature, 409(6819), 529-533. DOI: 10.1038/35054089
Diez-Gonzalez F, Callaway TR, Kizoulis MG, & Russell JB. (1998) Grain feeding and the dissemination of acid-resistant Escherichia coli from cattle. Science (New York, N.Y.), 281(5383), 1666-8. PMID: 9733511
- April 5, 2013
- 02:12 PM
- 85 views
An “Acceptable” GMO?
by Viet Le in Amasian Science
What if an already existing gene variant with a desired trait from one organism is genetically engineered into another organism of the same species?... Read more »
Liu, S., Kandoth, P., Warren, S., Yeckel, G., Heinz, R., Alden, J., Yang, C., Jamai, A., El-Mellouki, T., Juvale, P.... (2012) A soybean cyst nematode resistance gene points to a new mechanism of plant resistance to pathogens. Nature, 492(7428), 256-260. DOI: 10.1038/nature11651
- March 13, 2013
- 02:29 PM
- 83 views
Battle of the Sperms
by Viet Le in Amasian Science
Inside every Drosophila melanogaster (fruit fly) female is a sperm battleground where sperm from two different males jockey with each other for the honor of fertilizing her eggs. By sequentially mating females with males [...]... Read more »
Lüpold S, Manier MK, Berben KS, Smith KJ, Daley BD, Buckley SH, Belote JM, & Pitnick S. (2012) How multivariate ejaculate traits determine competitive fertilization success in Drosophila melanogaster. Current biology : CB, 22(18), 1667-72. PMID: 22840512
- March 12, 2013
- 11:18 AM
- 61 views
Drug Resistance in MRSA is Finely-tuned
by Viet Le in Amasian Science
Cross-posted at PLOS Public Health Perspectives. In hindsight, shoving my hand into a narrow drinking glass wasn’t such a good idea. I learned this the hard way a few years [...]... Read more »
Kouyos R, Klein E, & Grenfell B. (2013) Hospital-Community Interactions Foster Coexistence between Methicillin-Resistant Strains of Staphylococcus aureus. PLoS pathogens, 9(2). PMID: 23468619
Arêde P, Milheiriço C, de Lencastre H, & Oliveira DC. (2012) The anti-repressor MecR2 promotes the proteolysis of the mecA repressor and enables optimal expression of β-lactam resistance in MRSA. PLoS Pathogens, 8(7). PMID: 22911052
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