2 posts · 476 views
I'm a visiting scientist at the EMBL-European Bioinformatics Institute. My research seeks to understand the forces that shape genes, genomes, and species, using computational and statistical methods.
A recent PNAS article entitled "￼Heavy use of equations impedes communication among biologists" has caught considerable attention.In my view, the problem is not so much with their observation (equation denser papers tend to collect fewer citations) as with their main conclusion:"To maximize the scientific impact of their work, biologists should consider reducing the equation density in the main text of their theoretical articles."These type of observational analyses (i.e. *not* randomise........ Read more »
Fawcett TW, & Higginson AD. (2012) Heavy use of equations impedes communication among biologists. Proceedings of the National Academy of Sciences of the United States of America. PMID: 22733777
We have been fortunate to publish two articles in last month's PLoS Computational Biology. The first one was on resolving the ortholog conjecture, and I have written about it at length in a guest post on Jonathan Eisen's blog.
This post focuses on the second paper, "Quality of Computationally Inferred Gene Ontology Annotations". Stimulated by Jonathan's story behind the paper series, I am going to try to put this work too in perspective.... Read more »
Skunca Nives, Altenhoff Adrian, & Dessimoz Christophe. (2012) Quality of computationally inferred gene ontology annotations. PLoS computational biology, 8(5). PMID: 22693439
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