by sandnsurf in Life in the Fast Lane
A 7 year-old girl was brought to hospital with lethargy, irritability and vomiting. A week previously she developed chicken pox, and was treated with regular aspirin and paracetamol for fever and discomfort.... Read more »
Glasgow JF, & Middleton B. (2001) Reye syndrome--insights on causation and prognosis. Archives of disease in childhood, 85(5), 351-3. PMID: 11668090
Schrör K. (2007) Aspirin and Reye syndrome: a review of the evidence. Paediatric drugs, 9(3), 195-204. PMID: 17523700
by sandnsurf in Life in the Fast Lane
You are asked to review a 73 year old lady who is in hospital for treatment of septic arthritis affecting a prosthetic right hip joint inserted 5 years earlier. The joint has been washed out and debrided twice, and she is receiving IV flucloxacillin and meropenem following culture of a methicillin-sensitive Staphylococcus aureus. She is on regular paracetamol for pain. Unfortunately, she has continued to deteriorate...
Related posts:Metabolic Muddle #003
Metabolic Muddle #001
Metabolic Muddle ........ Read more »
Dempsey GA, Lyall HJ, Corke CF, & Scheinkestel CD. (2000) Pyroglutamic acidemia: a cause of high anion gap metabolic acidosis. Critical care medicine, 28(6), 1803-7. PMID: 10890623
Mizock BA, & Mecher C. (2000) Pyroglutamic acid and high anion gap: looking through the keyhole?. Critical care medicine, 28(6), 2140-1. PMID: 10890683
Peter JV, Rogers N, Murty S, Gerace R, Mackay R, & Peake SL. (2006) An unusual cause of severe metabolic acidosis. The Medical journal of Australia, 185(4), 223-5. PMID: 16922670
by Chris Nickson in Life in the Fast Lane
The fourth rule of Expensive Scare Medicine: 'If you measure something and it is not normal, make it normal if it is safe to do so'. But beware! This can lead to a dangerous and insatiable desire for 'euboxia' - the pathophysiological state whereby 'all boxes on a pathology print-out are in the normal range'.... Read more »
Reade MC. (2009) Should we question if something works just because we don't know how it works?. Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 11(4), 235-6. PMID: 20001869
by Laika in Laika's Medliblog
Respiratory tract infections acquired in the intensive care unit (ICU) are important causes of morbidity and mortality, the most significant risk factor being mechanical ventilation. It is thought that hospital pneumonia commonly originates from flora colonized in the patient’s oropharynx (the area of the throat at the back of the mouth). Therefore, reduction of [...]... Read more »
de Smet, A., Kluytmans, J., Cooper, B., Mascini, E., Benus, R., van der Werf, T., van der Hoeven, J., Pickkers, P., Bogaers-Hofman, D., van der Meer, N.... (2009) Decontamination of the Digestive Tract and Oropharynx in ICU Patients. New England Journal of Medicine, 360(1), 20-31. DOI: 10.1056/NEJMoa0800394
de Smet, A., Kluytmans, J., Cooper, B., Mascini, E., Benus, R., van der Werf, T., van der Hoeven, J., Pickkers, P., Bogaers-Hofman, D., van der Meer, N.... (2009) Decontamination of the Digestive Tract and Oropharynx in ICU Patients. New England Journal of Medicine, 360(1), 20-31. DOI: 10.1056/NEJMoa0800394
de Smet, A., Kluytmans, J., Cooper, B., Mascini, E., Benus, R., van der Werf, T., van der Hoeven, J., Pickkers, P., Bogaers-Hofman, D., van der Meer, N.... (2009) Decontamination of the Digestive Tract and Oropharynx in ICU Patients. New England Journal of Medicine, 360(1), 20-31. DOI: 10.1056/NEJMoa0800394
de Smet, A., Kluytmans, J., Cooper, B., Mascini, E., Benus, R., van der Werf, T., van der Hoeven, J., Pickkers, P., Bogaers-Hofman, D., van der Meer, N.... (2009) Decontamination of the Digestive Tract and Oropharynx in ICU Patients. New England Journal of Medicine, 360(1), 20-31. DOI: 10.1056/NEJMoa0800394
de Smet, A., Kluytmans, J., Cooper, B., Mascini, E., Benus, R., van der Werf, T., van der Hoeven, J., Pickkers, P., Bogaers-Hofman, D., van der Meer, N.... (2009) Decontamination of the Digestive Tract and Oropharynx in ICU Patients. New England Journal of Medicine, 360(1), 20-31. DOI: 10.1056/NEJMoa0800394
de Smet, A., Kluytmans, J., Cooper, B., Mascini, E., Benus, R., van der Werf, T., van der Hoeven, J., Pickkers, P., Bogaers-Hofman, D., van der Meer, N.... (2009) Decontamination of the Digestive Tract and Oropharynx in ICU Patients. New England Journal of Medicine, 360(1), 20-31. DOI: 10.1056/NEJMoa0800394
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