Editor’s Selections: Viral fossils, cloning mice from T cells, and bad mutations are good for you

Editor's Selections 3 Comments
By Vincent Racaniello

Vincent RacanielloVincent Racaniello selects several notable posts each week from molecular and cellular biology and virology. He blogs at virology blog.

  • Investigating the natural history of viruses is a challenge because they do not leave behind fossils. Viral prehistory is inferred by phylogenetic reconstruction, and endogenous proviruses – the remnants of retroviruses integrated into cellular genomes – contribute mightily.
  • T cell receptor transgenic mice have led to many advances in immunology, but they are time consuming to produce. Now it is possible to clone mice from a T single cell. All the T cells in these mice only recognize the desired antigen, instead of several trillion different ones.
  • Many evolutionary biologists also assume that deleterious mutations are prohibitive for evolution. A simulation of evolution in a fitness landscape shows that the population crosses two valleys. This would not have occurred if deleterious mutations were not allowed, proving that such mutations are beneficial.

I’ll be back next Friday with more selections.

Was your post selected? Copy the text below and place it on your blog post to display a custom "Editor's Selection" icon!

Editor's Selection Icon<span style="float: left; padding: 5px;"><a href="http://researchblogging.org/news/?p=1244"><img alt="This post was chosen as an Editor's Selection for ResearchBlogging.org" src="http://www.researchblogging.org/public/citation_icons/rb_editors-selection.png" style="border:0;"/></a></span>

3 Responses to “Editor’s Selections: Viral fossils, cloning mice from T cells, and bad mutations are good for you”

  1. Alva Corle Says:
    January 23rd, 2012 at 10:03 am

    I am often to running a blog and i really recognize your content. The article has actually peaks my interest. I’m going to bookmark your web site and preserve checking for brand spanking new information.

  2. Kevin Says:
    January 31st, 2012 at 9:40 am

    This is indeed an eye opener for me. I by no means realized came across these facts until now. Thank you so considerably for sharing these superb insights with us and I hope that you will continue to do so.

  3. julien mesa Says:
    April 24th, 2012 at 4:37 pm

    36. hi!,I love your writing very a lot! proportion we keep in touch more about your post on AOL? I need a specialist on this area to resolve my problem. Maybe that is you! Having a look ahead to see you.

Leave a Reply

Icons by N.Design Studio. Based on a theme by Ben Swift.
Entries RSS Comments RSS Log in