Editor’s Selections: Globalization and shifting disease ecologies, a molecular fossil’s tale, and a gene polymorphism good malaria, bad for lupus

April 23rd, 2010 Editor's Selections 8 Comments
By Vincent Racaniello

Vincent RacanielloVincent Racaniello selects several notable posts each week from molecular and cellular biology and virology. He blogs at virology blog.

  • Multiple factors working synergistically are leaving humans more at risk of contracting infectious diseases. Globalization, ecological disruption, and reduced biodiversity all play a role.
  • Every living cell on earth carries a molecular fossil: the ribosome. Its structure provides hints about the origin of the genetic code.
  • A polymorphism in the human gene FCGR2B is associated with susceptibility to systemic lupus erythematosus (SLE). The same mutation leads to a non-functional Fc gamma receptor IIb that is important for protection against malaria. The survival advantage explains its prevalence in certain populations despite the increased risk of SLE.

I’ll be back next Friday with more selections.

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