Editor’s Selections: It’s not lonely at the top, pathogenesis of Spanish flu, and sequencing on the benchtopFebruary 11th, 2011 Editor's Selections 4 Comments
Vincent Racaniello selects several notable posts each week from molecular and cellular biology and virology. He unravels viruses at virology blog.
- High levels of the immunosuppressive testosterone are associated with a high dominance rank. In a study of west Ugandan chimps, higher ranking animals had higher testosterone levels and greater parasite burden than the lower ranking ones.
- The ability to reconstruct the 1918 pandemic influenza virus strain from the genome sequence has allowed research into why the virus was particularly virulent. The results of experiments in ferrets implicate the viral HA glycoprotein and RNA polymerase complex in this property.
- DNA sequencing yields yields have skyrocketed from 10 gigabases per run to the current and outrageous 180-200 gb. Now companies are taking another approach, to bring sequencing to the masses at a price most labs can afford: a benchtop sequencer with short run times and appreciable read lengths (100bp) for under $50K.
I’ll be back next Friday with more selections.