Editor’s Selections: Of warts and men, the black death genome, and a chimeric virus to cure leukemiaOctober 21st, 2011 Editor's Selections 1 Comment
Vincent Racaniello selects several notable posts each week from molecular and cellular biology and virology. He unravels viruses at virology blog.
- Every profession has its hazards. Veterinarians suffer bites and scratches, office workers develop carpal tunnel syndrome, and fish-mongers and those intimately involved in the meat-handling trade are more likely to be infected with a certain strain of human papillomavirus.
- Ancient, degraded fragments of Yersinia pests have been fished out of bone and teeth extracts from the East Smithfield Black Death cemetery. The similarity of the Black Death strain with modern strains validates public health and biosecurity concerns over the plague.
- A patient with refractory chronic myelogenous leukemia (CLL) was treated by removing T cells from the patient, infecting them with an HIV vector encoding a chimeric antigen receptor with specificity for the B-cell antigen CD19. One month after infusing the patient with the transducer T cells there were no detectable tumor cells in the patient’s blood.
I’ll be back next Friday with more selections.