Editor’s Selections: M cells – gatekeepers or gateway in the gut, a home for bugs in our appendix, and exome sequencing bags a rare disease

Editor's Selections 1 Comment
By Vincent Racaniello

Vincent RacanielloVincent Racaniello selects several notable posts each week from molecular and cellular biology and virology. He blogs at virology blog.

  • Transcytosis by microfold (M) cells, specialised intestinal cells located over mucosal lymphoid tissue called Peyer’s patches, is important for sampling microorganisms in the gut. The immune response to bacteria is mediated by glycoprotein 2, which is the M cell receptor for type I pili.
  • The appendix has long been considered a useless, vestigial organ, because it can be removed with no visibly harmful effects. Recent evidence indicates that recent evidence posits that it plays a crucial role in maintaining important gut symbionts.
  • The damaged gene in Miller’s syndrome, a rare Mendelian disorder, was identified by sequencing only 30 MB of the genome from four individuals with the affliction.

I’ll be back next Friday with more selections.

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One Response to “Editor’s Selections: M cells – gatekeepers or gateway in the gut, a home for bugs in our appendix, and exome sequencing bags a rare disease”

  1. antique sewing machines Says:
    February 10th, 2010 at 3:46 am

    What are you talking about ??!!!! I’d tell you to visit my site but I dont think you would be able to read it??!! arrrrggghhhhhh!!!

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