Post List

  • April 27, 2015
  • 08:32 PM
  • 7 views

A bacterium that loves Roman mythology, sharing with worms, and playing with nitrogen

by Rosin Cerate in Rosin Cerate

Opitutus terrae is a bacterium found in rice paddy soil. It's well suited to this environment, being able to operate without oxygen (rice paddies are flooded with water, limiting the movement of gases from the atmosphere into the soil) and capable of eating chains of sugar made by rice plants (which are introduced into the soil when paddies are plowed at the end of a harvest). O. terrae was first isolated from a rice paddy in Vercelli, a city in northern Italy. Vercelli is situated in the Po Val........ Read more »

  • April 27, 2015
  • 02:03 PM
  • 14 views

Google searches for ‘n-word’ associated with black mortality

by Dr. Jekyll in Lunatic Laboratories

Google searches could unveil patterns in Black mortality rates across the US, according to a new study. Researchers found that those areas with greater levels of racism, as indexed by the proportion of Google searches containing the “n-word,” had higher mortality rates among Blacks. The study is the first to examine an Internet query-based measure of racism in relation to mortality risk.... Read more »

Chae, D., Clouston, S., Hatzenbuehler, M., Kramer, M., Cooper, H., Wilson, S., Stephens-Davidowitz, S., Gold, R., & Link, B. (2015) Association between an Internet-Based Measure of Area Racism and Black Mortality. PLOS ONE, 10(4). DOI: 10.1371/journal.pone.0122963  

  • April 27, 2015
  • 01:39 PM
  • 9 views

Parasite-Infected Bumblebees Seek out Flowers with Nicotine

by beredim in Strange Animals



 A buff-tailed bumblebee (Bombus terrestris

Buff-tailed bumblebees (Bombus terrestris) that have been infected by parasites seek out flowers with nicotine in their nectar, according to a new study by researchers at the Royal Holloway University of London and Queen Mary University of London, UK.

Apparently, the nicotine in the flowers slows the progression of disease in infected bees but has ... Read more »

  • April 27, 2015
  • 12:28 PM
  • 13 views

Boron and the Permian extinction: a glimpse into the past gives a hint of the future

by Jonathan Trinastic in Goodnight Earth

How will ocean acidification from anthropogenic CO2 emissions affect marine life? Recent work studying a similar time during the Permian extinction 200 million years ago gives a clue.... Read more »

Clarkson MO, Kasemann SA, Wood RA, Lenton TM, Daines SJ, Richoz S, Ohnemueller F, Meixner A, Poulton SW, & Tipper ET. (2015) Ocean acidification and the Permo-Triassic mass extinction. Science (New York, N.Y.), 348(6231), 229-32. PMID: 25859043  

  • April 27, 2015
  • 10:50 AM
  • 10 views

ADHD and Vehicular Accident Risk

by William Yates, M.D. in Brain Posts

Attention and impulsive behaviors found in attention deficit hyperactivity disorder (ADHD) can contribute to accident risk in children and adults.A recent study of adult drivers in France provides evidence for increased accident risk in adults with ADHD.Researchers at the Bordeaux University Hospital interviewed a series of adult drivers seen in the emergency department following a road traffic crash.A total of 777 eligible subjects completed assessments of accident information, distraction expo........ Read more »

  • April 27, 2015
  • 08:34 AM
  • 19 views

Phytozome notice, new and improved v10 coming soon

by Mary in OpenHelix

This announcement came out while I was at a conference last week–but I wanted to pass it along. This appears to be a big change in the way Phytozome works. And there will be down-time before it rolls out, starting May 1. I like to post major announcements from mailing lists because I know everyone […]... Read more »

Goodstein D. M., R. Howson, R. Neupane, R. D. Hayes, J. Fazo, T. Mitros, W. Dirks, U. Hellsten, N. Putnam, & D. S. Rokhsar. (2011) Phytozome: a comparative platform for green plant genomics. Nucleic Acids Research, 40(D1). DOI: http://dx.doi.org/10.1093/nar/gkr944  

  • April 27, 2015
  • 07:00 AM
  • 14 views

Role of EBV LMP-2A and LMP1 in inducing autophagy

by thelonevirologist in Virology Tidbits

Under conditions of cell stress such as nutrient deprivation or as a result of the accumulation of damaged organelles and misfolded proteins a lysosomal pathway is induced which degrades proteins as well organelles independent of the proteasomal pathway. The core machinery of this pathway -termed autophagy from the Greek  auto-, "self" and phagein, "to eat” (literally “selfeating”) - was discovered in genetic screens of yeast for genes required for survival ........ Read more »

Xi X, Zhang X, Wang B, Wang T, Wang J, Huang H, Wang J, Jin Q, & Zhao Z. (2013) The interplays between autophagy and apoptosis induced by enterovirus 71. PloS one, 8(2). PMID: 23437282  

Liu Y, & Levine B. (2015) Autosis and autophagic cell death: the dark side of autophagy. Cell death and differentiation, 22(3), 367-76. PMID: 25257169  

Liu Y, Shoji-Kawata S, Sumpter RM Jr, Wei Y, Ginet V, Zhang L, Posner B, Tran KA, Green DR, Xavier RJ.... (2013) Autosis is a Na ,K -ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia. Proceedings of the National Academy of Sciences of the United States of America, 110(51), 20364-71. PMID: 24277826  

Young, L., & Rickinson, A. (2004) Epstein–Barr virus: 40 years on. Nature Reviews Cancer, 4(10), 757-768. DOI: 10.1038/nrc1452  

Busson P, McCoy R, Sadler R, Gilligan K, Tursz T, & Raab-Traub N. (1992) Consistent transcription of the Epstein-Barr virus LMP2 gene in nasopharyngeal carcinoma. Journal of virology, 66(5), 3257-62. PMID: 1313931  

Li Y, Zhang L, Zhou J, Luo S, Huang R, Zhao C, & Diao A. (2015) Nedd4 E3 ubiquitin ligase promotes cell proliferation and autophagy. Cell proliferation. PMID: 25809873  

Kuang E, Qi J, & Ronai Z. (2013) Emerging roles of E3 ubiquitin ligases in autophagy. Trends in biochemical sciences, 38(9), 453-60. PMID: 23870665  

Xia P, Wang S, Du Y, Zhao Z, Shi L, Sun L, Huang G, Ye B, Li C, Dai Z.... (2013) WASH inhibits autophagy through suppression of Beclin 1 ubiquitination. The EMBO journal, 32(20), 2685-96. PMID: 23974797  

  • April 27, 2015
  • 04:36 AM
  • 22 views

When optimal outcome in autism meets ESSENCE

by Paul Whiteley in Questioning Answers

I recently came across the paper by Martina Barnevik Olsson and colleagues [1] (open-access) and their rather interesting take on the issue of optimal outcome and autism (see here for some background on this concept).Based on the idea that a diagnosis of autism or autism spectrum disorder (ASD) might not be as immutable as perhaps once thought (as in 'no longer meeting the diagnostic criteria for the condition'), Barnevik Olsson et al reported that loss of the autism/ASD label does not........ Read more »

Barnevik Olsson, M., Westerlund, J., Lundström, S., Giacobini, M., Fernell, E., & Gillberg, C. (2015) “Recovery” from the diagnosis of autism – and then?. Neuropsychiatric Disease and Treatment, 999. DOI: 10.2147/NDT.S78707  

  • April 27, 2015
  • 12:05 AM
  • 14 views

As if Sustaining a TBI was not Enough….TBI May Accelerate Brain Aging

by Jane McDevitt in Sports Medicine Research (SMR): In the Lab & In the Field

A patient with a moderate or severe traumatic brain injury is likely to have structural brain changes that are associated with an older brain than his/her actual age.... Read more »

Cole JH, Leech R, Sharp DJ, & Alzheimer's Disease Neuroimaging Initiative. (2015) Prediction of brain age suggests accelerated atrophy after traumatic brain injury. Annals of Neurology, 77(4), 571-81. PMID: 25623048  

  • April 26, 2015
  • 11:53 PM
  • 22 views

FDA says no to marketing FDDNP for CTE

by The Neurocritic in The Neurocritic

The U.S. Food and Drug Administration recently admonished TauMark™, a brain diagnostics company, for advertising brain scans that can diagnose chronic traumatic encephalopathy (CTE), Alzheimer's disease, and other types of dementia. The Los Angeles Times reported that the FDA ordered UCLA researcher Dr. Gary Small and his colleague/business partner Dr. Jorge Barrio to remove misleading information from their company website (example shown below).CTE has been in the news because the neurodegene........ Read more »

Barrio, J., Small, G., Wong, K., Huang, S., Liu, J., Merrill, D., Giza, C., Fitzsimmons, R., Omalu, B., Bailes, J.... (2015) In vivo characterization of chronic traumatic encephalopathy using [F-18]FDDNP PET brain imaging. Proceedings of the National Academy of Sciences, 201409952. DOI: 10.1073/pnas.1409952112  

Zimmer, E., Leuzy, A., Gauthier, S., & Rosa-Neto, P. (2014) Developments in Tau PET Imaging. The Canadian Journal of Neurological Sciences, 41(05), 547-553. DOI: 10.1017/cjn.2014.15  

  • April 26, 2015
  • 11:21 PM
  • 18 views

References to alcohol in UK pop music are on the increase

by BPS Research Digest in BPS Research Digest

"My wine is good to me, it helps me pass the time. And my good old buddy whiskey keeps me warmer than the sunshine," Aloe Blacc – I need a dollar, 2011.Psychologists have documented a striking increase in references to alcohol and heavy drinking in the lyrics of UK chart music. They warn this could mean that attempts to control the direct advertising of alcohol to young people will be in vain, as pop music is effectively spreading a positive message on the drinks companies' behalf.Katheri........ Read more »

  • April 26, 2015
  • 03:14 PM
  • 31 views

Fatal attraction: the intuitive appeal of GMO opposition

by Dr. Jekyll in Lunatic Laboratories

A team of Belgian philosophers and plant biotechnologists have turned to cognitive science to explain why opposition to genetically modified organisms (GMOs) has become so widespread, despite positive contributions GM crops have made to sustainable agriculture. They argue that the human mind is highly susceptible to the negative and often emotional representations put out by certain environmental groups and other opponents of GMOs. The researchers urge the general public to form opinions on GMOs........ Read more »

Blancke, S., Van Breusegem, F., De Jaeger, G., Braeckman, J., & Van Montagu, M. (2015) Fatal attraction: the intuitive appeal of GMO opposition. Trends in Plant Science. DOI: 10.1016/j.tplants.2015.03.011  

  • April 26, 2015
  • 02:48 PM
  • 26 views

Single Pill Combination Therapy For Some Hepatitis C Subtypes

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Stefan Zeuzem, MD Professor of Medicine Chief Department of Medicine Goethe University Hospital Frankfurt Medical Research: What is the background for this study? What are the main findings? Dr. Zeuzem: Interferon- and ribavirin-free regimens are needed to … Continue reading →
The post Single Pill Combination Therapy For Some Hepatitis C Subtypes appeared first on MedicalResearch.com Medical ........ Read more »

MedicalResearch.com Interview with: Stefan Zeuzem, MD. (2015) Single Pill Combination Therapy For Some Hepatitis C Subtypes. MedicalResearch.com. info:/

  • April 26, 2015
  • 01:47 PM
  • 26 views

Genetic Basis of Transcriptome Diversity in Drosophila melanogaster

by Dave Bridges in Metabolism Preprints

This preprint from Trudy Mackay‘s group at NC State uses a recombinant inbred series of flies known as the Drosophila Genome Reference Panel (DGRP) to evaluate how genetic variation affects transcription.  To do this they extracted RNA from whole flies, pooled from males and females of each of the 192 recombinant inbred fly lines.  They fit…... Read more »

Wen Huang, Mary Anna Carbone, Michael Magwire, Jason Peiffer, Richard Lyman, Eric Stone, Robert Anholt, & Trudy Mackay. (2015) Genetic Basis of Transcriptome Diversity in Drosophila melanogaster. bioRxiv. info:/10.1101/018325

  • April 26, 2015
  • 10:27 AM
  • 29 views

The Story Behind the Paper: The role of TORC1 in muscle development in Drosophila

by Dave Bridges in Bridges Lab Commentaries

A summary of our recent paper on the role of the TORC1 complex in drosophila muscle function... Read more »

Hatfield, I., Harvey, I., Yates, E., Redd, J., Reiter, L., & Bridges, D. (2015) The role of TORC1 in muscle development in Drosophila. Scientific Reports, 9676. DOI: 10.1038/srep09676  

  • April 25, 2015
  • 07:13 PM
  • 23 views

Malaria Vaccine Has Potential To Contribute To Disease Control

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Mary J Hamel, M.D. Chief, Strategic and Applied Sciences Unit, And Deputy Branch Chief for Science, CDC Malaria Branch US Centers for Disease Control and Prevention 1600 Clifton Rd, NE, MS A06 Atlanta GA 30333 Dr. Hamel … Continue reading →
The post Malaria Vaccine Has Potential To Contribute To Disease Control appeared first on MedicalResearch.com Medical Research Interviews and News.
... Read more »

MedicalResearch.com Interview with: Mary J Hamel, M.D. (2015) Malaria Vaccine Has Potential To Contribute To Disease Control . MedicalResearch.com. info:/

  • April 25, 2015
  • 06:56 PM
  • 26 views

Carotid Artery Stenting: Comparison Of Embolic-Prevention Devices

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with Jay Giri, MD MPH Director, Peripheral Intervention Assistant Professor of Clinical Medicine University of Pennsylvania MedicalResearch: What is the background for this study? What are the main findings? Dr. Giri: Carotid artery stents are placed by vascular … Continue reading →
The post Carotid Artery Stenting: Comparison Of Embolic-Prevention Devices appeared first on MedicalResearch.com Medi........ Read more »

MedicalResearch.com Interview with Jay Giri, MD MPH. (2015) Carotid Artery Stenting: Comparison Of Embolic-Prevention Devices. MedicalResearch.com. info:/

  • April 25, 2015
  • 06:37 PM
  • 26 views

Antibacterial Gloves May Reduce Cross Contamination In ICU Setting

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Ojan Assadian, M.D., DTMH Professor for Skin Integrity and Infection Prevention Institute for Skin Integrity and Infection Prevention School of Human & Health Sciences University of Huddersfield Queensgate, Huddersfield UK MedicalResearch: What is the background for this … Continue reading →
The post Antibacterial Gloves May Reduce Cross Contamination In ICU Setting appeared first on Medi........ Read more »

MedicalResearch.com Interview with:Ojan Assadian, M.D., DTMH. (2015) Antibacterial Gloves May Reduce Cross Contamination In ICU Setting. MedicalResearch.com. info:/

  • April 25, 2015
  • 06:21 PM
  • 25 views

Leveraging Big Data to Accelerate Drug Discovery

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Neel S. Madhukar Graduate student in the lab of Olivier Elemento, PhD, Associate Professor Head, Laboratory of Cancer Systems Biology Department of Physiology and Biophysics Institute for Computational Biomedicine Weill Cornell Medical College Medical Research: What is … Continue reading →
The post Leveraging Big Data to Accelerate Drug Discovery appeared first on MedicalResearch.com Medical ........ Read more »

MedicalResearch.com Interview with:Neel S. MadhukarGraduate student in the lab of, & Olivier Elemento, PhD, Associate Professor. (2015) Leveraging Big Data to Accelerate Drug Discovery . MedicalResearch.com. info:/

  • April 25, 2015
  • 01:59 PM
  • 63 views

Mental disorders do not predict violence, so please stop

by Dr. Jekyll in Lunatic Laboratories

When Sandy Hook happened, it was so shocking that to this day, some don’t actually believe it happened. Shortly after, something frustrating happened, the shooter was labeled with aspergers. This helped drive the mental health and violence connection to the point that Time came out with an article dispelling that myth. Even now according to new longitudinal study of delinquent youth, most psychiatric disorders – including depression — do not predict future violent behavior. The only except........ Read more »

Elkington, K., Teplin, L., Abram, K., Jakubowski, J., Dulcan, M., & Welty, L. (2015) Psychiatric Disorders and Violence: A Study of Delinquent Youth After Detention. Journal of the American Academy of Child , 54(4), 302-31200000. DOI: 10.1016/j.jaac.2015.01.002  

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