Post List

  • March 18, 2017
  • 04:58 AM
  • 251 views

HSV-2 gestational infection and offspring autism risk

by Paul Whiteley in Questioning Answers

"In our cohort, high levels of antibodies to herpes simplex virus 2 at midpregnancy were associated with an elevated risk of autism spectrum disorder in male offspring. These findings provide support for the hypothesis that gestational infection may contribute to the pathogenesis of autism spectrum disorder and have the potential to drive new efforts to monitor women more closely for cryptic gestational infection and to implement suppressive therapy during pregnancy."That was the conclusion reac........ Read more »

Milada Mahic, Siri Mjaaland, Hege Marie Bøvelstad, Nina Gunnes, Ezra Susser, Michaeline Bresnahan, Anne-Siri Øyen, Bruce Levin, Xiaoyu Che, Deborah Hirtz.... (2017) Maternal Immunoreactivity to Herpes Simplex Virus 2 and Risk of Autism Spectrum Disorder in Male Offspring. mSphere. info:/10.1128/mSphere.00016-17

  • March 17, 2017
  • 05:29 PM
  • 255 views

Unethical "Stem Cell" Therapy for Autism In India?

by Neuroskeptic in Neuroskeptic_Discover

I just read a concerning paper about an experimental stem cell treatment for children with autism.





The authors are Himanshu Bansal and colleagues of India. The senior author, Prasad S Koka, is the Editor-in-Chief of the Journal of Stem Cells where the paper appeared, which raises questions about whether the manuscript received a thorough peer review. Koka is actually an author on all five of the research papers published in that issue of the journal. But that's a minor issue compared ... Read more »

Bansal H, Verma P, Agrawal A, Leon J, Sundell IB, Koka PS. (2016) A Short Study Report on Bone Marrow Aspirate Concentrate Cell Therapy in Ten South Asian Indian Patients with Autism. Journal of Stem Cells, 11(1). info:/

  • March 17, 2017
  • 07:02 AM
  • 237 views

Don’t do this at work, beards, ear worms, narcissists, &  discarding advances in knowledge

by Rita Handrich in The Jury Room

Here’s another this-and-that post documenting things you need to know but that we don’t want to do a whole post about–so you get a plethora of factoids that will entertain your family and entrance your co-workers. Or at least be sort of fun to read and (probably) as awe-inspiring as the stack of vegetables and […]... Read more »

Beaman, CP, Powell, K, & Rapley, E. (2015) Want to block eagworms from conscious awareness? Buy gum! . The Quarterly Journal of Experimental Psychology,, 68(6), 1049-1057. info:/

Hepper EG, Hart CM, & Sedikides C. (2014) Moving Narcissus: Can Narcissists Be Empathic?. Personality , 40(9), 1079-1091. PMID: 24878930  

  • March 17, 2017
  • 07:00 AM
  • 235 views

Friday Fellow: Pliable Brachionus

by Piter Boll in Earthling Nature

by Piter Kehoma Boll Charles Darwin had already noticed that small animals, such as those found in zooplankton, are widely distributed around the world, even those that are found in small ponds of freshwater. This seemed to go against the … Continue reading →... Read more »

  • March 17, 2017
  • 03:39 AM
  • 256 views

Fatty acids and autism meta-analysed yet again (with a different result?)

by Paul Whiteley in Questioning Answers

OK I'm a little confused right now.Not so long ago I talked about the paper from Horvath and colleagues [1] (see here) concluding that "the limited data currently available suggest that ω-3 FA [omega-3 fatty acid] supplementation does not enhance the performance of children with ASD [autism spectrum disorder]." Such a conclusion was based on the application of a systematic review and meta-analysis of the available peer-reviewed literature up to August 2016.Now however, another sy........ Read more »

  • March 16, 2017
  • 03:44 AM
  • 274 views

Autoimmune disease(s) and ADHD: birds of a feather?

by Paul Whiteley in Questioning Answers

"A personal history and a maternal history of autoimmune disease were associated with an increased risk of ADHD [attention-deficit hyperactivity disorder]. The previously reported association between type 1 diabetes and ADHD was confirmed. In addition, specific parental autoimmune diseases were associated with ADHD in offspring."So said the study results published by Nielsen and colleagues [1] including "a study population of 983,680 individuals followed from 1995 to 2012." Reliant once aga........ Read more »

  • March 15, 2017
  • 12:57 PM
  • 263 views

Emotional Intelligence and the Physician

by William Yates, M.D. in Brain Posts

Emotional intelligence (EI) is characterized by the ability to recognize emotional states in self and in others.This emotional recognition may be helpful in guiding behavior and in improving interpersonal relationships.It seems logical on a face validity level to assume that higher levels of EI would be good in the selection of students for medical school.However, there are few studies assessing EI in physicians. There are fewer studies that examine whether EI influences physician behavior, pati........ Read more »

  • March 15, 2017
  • 09:43 AM
  • 255 views

The Incredible Lesion-Proof Brain?

by Neuroskeptic in Neuroskeptic_Discover

How much damage can the brain take and still function normally? In a new paper, A Lesion-Proof Brain?, Argentinian researchers Adolfo M. García et al. describe the striking case of a woman who shows no apparent deficits despite widespread brain damage.



The patient, "CG", is 44 years old and was previously healthy until a series of strokes lesioned large parts of her brain, as shown below.

García et al. say that the damage included "extensive compromise of the right fronto-temporo-parie... Read more »

  • March 15, 2017
  • 08:30 AM
  • 257 views

CHL1 Hypermethylation in Breast Cancer

by Esperanza Martín Sánchez in EpiBeat

Breast cancer (BC) is the most common cancer among women and one of the leading causes of cancer-related deaths worldwide (1-3). It is a clinically heterogeneous disease, with at least 5 different subtypes (4) and quite variable prognosis, even within a subtype. In spite of early detection programmes, unfortunately 20-30% of early stage cases will eventually experience recurrence and develop distant metastasis. However, currently, there is no acceptable method for monitoring patients who are lik........ Read more »

Martín-Sánchez E, Mendaza S, Ulazia-Garmendia A, Monreal-Santesteban I, Blanco-Luquin I, Córdoba A, Vicente-García F, Pérez-Janices N, Escors D, Megías D.... (2017) CHL1 hypermethylation as a potential biomarker of poor prognosis in breast cancer. Oncotarget. PMID: 28178655  

Stefansson OA, Moran S, Gomez A, Sayols S, Arribas-Jorba C, Sandoval J, Hilmarsdottir H, Olafsdottir E, Tryggvadottir L, Jonasson JG.... (2015) A DNA methylation-based definition of biologically distinct breast cancer subtypes. Molecular oncology, 9(3), 555-68. PMID: 25468711  

He LH, Ma Q, Shi YH, Ge J, Zhao HM, Li SF, & Tong ZS. (2013) CHL1 is involved in human breast tumorigenesis and progression. Biochemical and biophysical research communications, 438(2), 433-8. PMID: 23906755  

Smith RA, Andrews K, Brooks D, DeSantis CE, Fedewa SA, Lortet-Tieulent J, Manassaram-Baptiste D, Brawley OW, & Wender RC. (2016) Cancer screening in the United States, 2016: A review of current American Cancer Society guidelines and current issues in cancer screening. CA: a cancer journal for clinicians, 66(2), 96-114. PMID: 26797525  

Feng W, Shen L, Wen S, Rosen DG, Jelinek J, Hu X, Huan S, Huang M, Liu J, Sahin AA.... (2007) Correlation between CpG methylation profiles and hormone receptor status in breast cancers. Breast cancer research : BCR, 9(4). PMID: 17764565  

Karsli-Ceppioglu S, Dagdemir A, Judes G, Ngollo M, Penault-Llorca F, Pajon A, Bignon YJ, & Bernard-Gallon D. (2014) Epigenetic mechanisms of breast cancer: an update of the current knowledge. Epigenomics, 6(6), 651-64. PMID: 25531258  

Widschwendter M, Siegmund KD, Müller HM, Fiegl H, Marth C, Müller-Holzner E, Jones PA, & Laird PW. (2004) Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen. Cancer research, 64(11), 3807-13. PMID: 15172987  

Senchenko VN, Krasnov GS, Dmitriev AA, Kudryavtseva AV, Anedchenko EA, Braga EA, Pronina IV, Kondratieva TT, Ivanov SV, Zabarovsky ER.... (2011) Differential expression of CHL1 gene during development of major human cancers. PloS one, 6(3). PMID: 21408220  

  • March 15, 2017
  • 04:30 AM
  • 229 views

Balance Assessments Unable to Predict ACL Injury in Elite Female Athletes

by Nicole Cattano in Sports Medicine Research (SMR): In the Lab & In the Field

Balance assessments were not associated with anterior cruciate ligament injury risk among elite female handball and soccer athletes.
... Read more »

  • March 15, 2017
  • 04:08 AM
  • 271 views

The extra-intestinal effects of coeliac disease autoimmunity?

by Paul Whiteley in Questioning Answers

"In 3.5-year-old children, CDA [coeliac disease autoimmunity] is associated with increased reports of child depression and anxiety, aggressive behavior, and sleep problems when mothers are unaware of their child’s CDA status."So said the findings reported by Laura Smith and colleagues [1] (open-access available here) adding to an emerging body of peer-reviewed research suggesting that the archetypal 'gluten is the baddie' autoimmune condition known as coeliac disease might, when not manag........ Read more »

Smith LB, Lynch KF, Kurppa K, Koletzko S, Krischer J, Liu E, Johnson SB, Agardh D, & TEDDY study group. (2017) Psychological Manifestations of Celiac Disease Autoimmunity in Young Children. Pediatrics. PMID: 28219962  

  • March 14, 2017
  • 08:26 PM
  • 248 views

‘I’m not listening to you!’ Interacting in a linguistically diverse society

by Ingrid Piller in Language on the Move

On December 23, 2016, as most Australians were winding down for the holiday week ahead, Faysal Ishak Ahmed, a 27-year-old...... Read more »

Kenison TC, Madu A, Krupat E, Ticona L, Vargas IM, & Green AR. (2017) Through the Veil of Language: Exploring the Hidden Curriculum for the Care of Patients With Limited English Proficiency. Academic medicine : journal of the Association of American Medical Colleges, 92(1), 92-100. PMID: 27166864  

  • March 14, 2017
  • 01:30 PM
  • 245 views

Internationalization as an indicator of journal performance in Brazil: the case of Psychology

by SciELO in SciELO in Perspective

The path to strengthening scientific publications almost always goes through internationalization. Publishing in English, however, is not enough to reach a truly global audience and indices comparable to the most prestigious journals. A study on the degree of internationalization of Brazilian psychology journals shows how to walk this path. … Read More →... Read more »

Gamba, E., Packer, A., & Meneghini, R. (2015) Pathways to Internationalize Brazilian Journals of Psychology. Psicologia: Reflexão e Crítica, 66-71. DOI: 10.1590/1678-7153.20152840010  

  • March 14, 2017
  • 08:05 AM
  • 248 views

Solar Science with the Atacama Large Millimeter/Submillimeter Array — A New View of Our Sun by S. Wedemeyer

by CESRA in Solar Radio Science

The Atacama Large Millimeter/submillimeter Array (ALMA), which consists of 66 antennas placed on the Chajnantor plateau in the Chilean Andes, has already produced impressive results for a large range of astronomical objects. Regular observations of the Sun have been carried out for the first time in December 2016 and exciting results can be expected soon. ALMA combines high spatial, temporal, and spectral resolution with the diagnostic advantages of radiation at [...]... Read more »

Wedemeyer, S., Bastian, T., Brajša, R., Hudson, H., Fleishman, G., Loukitcheva, M., Fleck, B., Kontar, E., De Pontieu, B., Yagoubov, P.... (2015) Solar Science with the Atacama Large Millimeter/Submillimeter Array—A New View of Our Sun. Space Science Reviews, 200(1-4), 1-73. DOI: 10.1007/s11214-015-0229-9  

  • March 14, 2017
  • 07:08 AM
  • 63 views

Nonlinear effects in shallow water waves

by Mirjam Sophia Glessmer in Adventures in Oceanography and Teaching

I recently googled for something related to the shape of waves and came across a photo of a wave that caught my eye, and it took me to a journey that lead to the article “nonlinear shallow ocean wave soliton interactions on flat beaches” by Ablowitz and Baldwin (2012). What’s discussed in that article is that while…... Read more »

Mark J. Ablowitz, & Douglas E. Baldwin. (2012) Nonlinear shallow ocean wave soliton interactions on flat beaches. Physical Review E, vol. 86(3), pp. 036305 (2012). arXiv: 1208.2904v1

  • March 14, 2017
  • 03:56 AM
  • 280 views

Depression in parents of children with autism

by Paul Whiteley in Questioning Answers

"Mothers (OR 2.95, 95% CI 2.81-3.09) and fathers (OR 2.41, 95% CI 2.25-2.58) of children with ASD [autism spectrum disorder] were more likely to have a diagnosis of depression than parents of children without ASD."The paper by Cohrs and Leslie [1] is probably not going to win any awards for novelty when it comes to their findings that: "Autism Spectrum Disorder (ASD) in children can have secondary effects on the child's parents." It does however represent another important piece of evidence........ Read more »

  • March 13, 2017
  • 11:38 AM
  • 246 views

Earliest Brain Changes in Alzheimer's Disease

by William Yates, M.D. in Brain Posts

Amyloid brain plaques are well-known pathological changes associated with Alzheimer's disease. Changes preceding amyloid plaque build up are less well studied and understood. Some of this relates to limitations to current imaging technology.Klementieva and colleagues from Sweden and Spain recently published an important reserach topic in this area.Their studied used a rat model of Alzheimer's disease and imaging techniques that included infrared microspectroscopy and gel electrophoresis.The........ Read more »

Klementieva, O., Willén, K., Martinsson, I., Israelsson, B., Engdahl, A., Cladera, J., Uvdal, P., & Gouras, G. (2017) Pre-plaque conformational changes in Alzheimer’s disease-linked Aβ and APP. Nature Communications, 14726. DOI: 10.1038/ncomms14726  

  • March 13, 2017
  • 07:02 AM
  • 211 views

Identifying deception when the witness wears a face-covering veil

by Rita Handrich in The Jury Room

In 2014, we wrote about research investigating how people felt when a witness wore a veil such as some forms of a hijab or a niqab. Here were some of the findings we described in that research. We’ve written a number of times about bias against Muslims. But here’s a nice article with an easy […]... Read more »

Leach AM, Ammar N, England DN, Remigio LM, Kleinberg B, & Verschuere BJ. (2016) Less is more? Detecting lies in veiled witnesses. Law and Human Behavior, 40(4), 401-10. PMID: 27348716  

  • March 13, 2017
  • 03:29 AM
  • 289 views

Mitochondria support for mitochondrial activity in [some] autism

by Paul Whiteley in Questioning Answers

"This study examined the effect of common mitochondrial treatments on specific mitochondrial components in a group of children diagnosed with ASD [autism spectrum disorder], some of which also were diagnosed with co-morbid mitochondrial disease."That was the premise of the study results published by Leanna Delhey and colleagues [1] (open-access available here) and follows previous discussions suggesting that mitochondrial disease might not be totally unfamiliar to at least some autism ........ Read more »

Delhey LM, Nur Kilinc E, Yin L, Slattery JC, Tippett ML, Rose S, Bennuri SC, Kahler SG, Damle S, Legido A.... (2017) The Effect of Mitochondrial Supplements on Mitochondrial Activity in Children with Autism Spectrum Disorder. Journal of clinical medicine, 6(2). PMID: 28208802  

  • March 11, 2017
  • 04:45 PM
  • 247 views

Badass females are unpopular among praying mantids

by Piter Boll in Earthling Nature

by Piter Kehoma Boll One of the most iconic representations of praying mantids is that of a female eating the male after (or during) sex, an unpleasant scenario that starts with a beheading before the poor male even finishes his … Continue reading →... Read more »

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