Post List

  • March 2, 2017
  • 12:19 PM
  • 166 views

Improving Hearing-Aid Access in Older Adults

by William Yates, M.D. in Brain Posts

There are significant barriers to widespread use of hearing-aids in older adults with age-related hearing loss.Sensitivity to the stigma of wearing a hearing-aid is one barrier.Cost is another significant barrier. In the U.S., bilateral hearing-aid purchase amounts to a cost of $2400 to $5800. This cost is typically not covered by Medicare or other health insurance plans.I ran into a interesting manuscript on looking at an alternative less costlier approach to hearing-aid selection and purchase......... Read more »

  • March 2, 2017
  • 03:11 AM
  • 176 views

Subgroups in autism (without intellectual disability)

by Paul Whiteley in Questioning Answers

"Children with ASD [autism spectrum disorder] without ID [intellectual disability] could be differentiated into Moderate and Severe Social Impairment subgroups when core ASD symptoms were more closely examined."So said the findings reported by Felicity Klopper and colleagues [1] looking at an important part of the autism research scene related to the 'plurality' of the term autism and the seemingly vast range of presentations included under the label. Reliant on data obtained........ Read more »

Felicity Klopper, Renee Testa, Christos Pantelis, & Efstratios Skafidas. (2017) A cluster analysis exploration of autism spectrum disorder subgroups in children without intellectual disability. Research in Autism Spectrum Disorders. info:/10.1016/j.rasd.2017.01.006

  • March 1, 2017
  • 10:30 AM
  • 161 views

What kind of scratching post do cats prefer?

by CAPB in Companion Animal Psychology Blog

It’s important to provide cats with the right kind of scratching post – and reward them for using it.Inappropriate scratching is a fairly common complaint about cats. That’s inappropriate from the owner’s perspective, because from the cat’s point of view they are just doing what comes naturally. Research by Colleen Wilson DVM et al tells us what kind of scratching post to provide in order to keep both cat and owner happy.Cats scratch in order to mark their territory. It leaves a visual........ Read more »

Wilson C, Bain M, DePorter T, Beck A, Grassi V, & Landsberg G. (2016) Owner observations regarding cat scratching behavior: an internet-based survey. Journal of feline medicine and surgery, 18(10), 791-7. PMID: 26179574  

  • March 1, 2017
  • 09:27 AM
  • 150 views

Politics Trump Healthcare Information: News Coverage of the Affordable Care Act

by Jalees Rehman in The Next Regeneration

Gollust and colleagues found that 55% of the news stories either focused on the politics of the ACA such as political disagreements over its implementation (26.5%) or combined information regarding its politics with information on how it would affect healthcare insurance options (28.6%). Only 45% of the news stories focused exclusively on the healthcare insurance options provided by the law. The politics-focused news stories were also more likely to refer to the law as “Obamacare” wh........ Read more »

  • March 1, 2017
  • 08:00 AM
  • 128 views

Transient Imprinting of Genes in the Human Placenta

by Marta Sanchez Delgado in EpiBeat

When the fertilization occurs, the maternal and paternal pronuclei have thousands of opposite methylated regions. Most of this germline methylation are resolved during the postfertilization epigenetic reprogramming by active mechanism for the sperm-derived methylated regions and depending on DNA replication for the oocyte-derived ones. There is a subset of regions that are known to avoid this demethylation: the imprinted differentially methylated regions (DMRs). The imprinted DMRs are in general........ Read more »

Sanchez-Delgado M, Court F, Vidal E, Medrano J, Monteagudo-Sánchez A, Martin-Trujillo A, Tayama C, Iglesias-Platas I, Kondova I, Bontrop R.... (2016) Human Oocyte-Derived Methylation Differences Persist in the Placenta Revealing Widespread Transient Imprinting. PLoS genetics, 12(11). PMID: 27835649  

Smallwood SA, & Kelsey G. (2012) De novo DNA methylation: a germ cell perspective. Trends in genetics : TIG, 28(1), 33-42. PMID: 22019337  

Smith ZD, Chan MM, Humm KC, Karnik R, Mekhoubad S, Regev A, Eggan K, & Meissner A. (2014) DNA methylation dynamics of the human preimplantation embryo. Nature, 511(7511), 611-5. PMID: 25079558  

Barbaux S, Gascoin-Lachambre G, Buffat C, Monnier P, Mondon F, Tonanny MB, Pinard A, Auer J, Bessières B, Barlier A.... (2012) A genome-wide approach reveals novel imprinted genes expressed in the human placenta. Epigenetics, 7(9), 1079-90. PMID: 22894909  

Hanna CW, Peñaherrera MS, Saadeh H, Andrews S, McFadden DE, Kelsey G, & Robinson WP. (2016) Pervasive polymorphic imprinted methylation in the human placenta. Genome research, 26(6), 756-67. PMID: 26769960  

  • March 1, 2017
  • 07:02 AM
  • 123 views

So maybe it doesn’t pay to be beautiful  

by Doug Keene in The Jury Room

Or at least, maybe there is no “ugliness penalty” if you are not beautiful. We’ve written a number of times here about the many benefits given to those who are seen as beautiful or attractive. This paper debunks the stereotype and says that salary goes beyond appearance and individual differences matter too. The researchers used […]... Read more »

Kanazawa, S., & Still, MC. (2017) Is there really a beauty premium or an ugliness penalty on earnings?. Journal of Business and Psychology. info:/

  • March 1, 2017
  • 04:30 AM
  • 148 views

Timing is Everything & Fatigue is Inevitable

by Jane McDevitt in Sports Medicine Research (SMR): In the Lab & In the Field

Athletes suffered more lower extremity injuries towards the middle to end of the competition and practices, which suggest that fatigue may play a role in lower extremity injury risk.... Read more »

  • March 1, 2017
  • 03:13 AM
  • 171 views

Sex and age might affect comorbidity profiles in autism

by Paul Whiteley in Questioning Answers

The paper by Supekar and colleagues [1] provides some food for thought today specifically with the idea that comorbidity profiles accompanying autism might be influenced by age and gender in mind.To quote: "These results highlight crucial differences between cross-sectional comorbidity patterns and their interactions with sex and age, which may aid in the development of effective sex- and age-specific diagnostic/treatment strategies for ASD [autism spectrum disorder] and comorbid condi........ Read more »

Supekar K, Iyer T, & Menon V. (2017) The influence of sex and age on prevalence rates of comorbid conditions in autism. Autism research : official journal of the International Society for Autism Research. PMID: 28188687  

  • March 1, 2017
  • 03:12 AM
  • 131 views

The slowing down of the biggest scientific journal

by Richard Kunert in Brain's Idea

PLoS ONE started 11 years ago to disruptively change scholarly publishing. By now it is the biggest scientific journal out there. Why has it become so slow? Many things changed at PLoS ONE over the years, reflecting general trends in how researchers publish their work. For one thing, PLoS ONE grew enourmously. After publishing only […]... Read more »

Wakeling S, Willett P, Creaser C, Fry J, Pinfield S, & Spezi V. (2016) Open-Access Mega-Journals: A Bibliometric Profile. PloS one, 11(11). PMID: 27861511  

  • March 1, 2017
  • 12:44 AM
  • 138 views

Neurofeedback Training For Insomnia No Better Than Sham

by The Neurocritic in The Neurocritic





Neurofeedback training (NFT) is a procedure that tries to shape a participant's pattern of brain activity by providing real-time feedback, often in the form of a video game combined with other sensory stimuli that provide rewards when the “correct” state is achieved. The most common form of NFT uses EEG (brainwave) activity recorded non-invasively from the scalp. The EEG is a complex mixture

... Read more »

Manuel Schabus, Hermann Griessenberger, Maria-Teresa Gnjezda, Dominik P.J. Heib, Malgorzata Wislowska, Kerstin Hoedlmoser. (2017) Better than sham? A double-blind placebo-controlled neurofeedback study in primary insomnia. Brain. info:/10.1093/brain/awx011

Sitaram, R., Ros, T., Stoeckel, L., Haller, S., Scharnowski, F., Lewis-Peacock, J., Weiskopf, N., Blefari, M., Rana, M., Oblak, E.... (2016) Closed-loop brain training: the science of neurofeedback. Nature Reviews Neuroscience, 18(2), 86-100. DOI: 10.1038/nrn.2016.164  

  • February 28, 2017
  • 06:00 PM
  • 120 views

Cataloging a year of blogging: complexity in evolution, general models, and philosophy

by Artem Kaznatcheev in Evolutionary Games Group

Last month, with just hours to spare in January, I shared a linkdex of the 14 cancer-related posts from TheEGG in 2016. Now, as February runs out, it’s time to reflect on the 15 non cancer-specific posts from last year. Although, as we’ll see, some of them are still related to mathematical oncology. With a […]... Read more »

  • February 28, 2017
  • 02:00 PM
  • 124 views

A Weekend Camping Trip Is Enough to Reset Your Internal Clock

by Elizabeth Preston in Inkfish



Humans have been fighting our internal clocks ever since we invented sitting around a campfire. We have powerful natural rhythms that keep us on a 24-hour cycle; if you've ever been steamrollered by jet lag after an intercontinental flight, you know how powerful those rhythms are. But we muffle them with caffeine, alarm clocks, and electric lights. It's easy to undo the damage, though. One weekend of camping can do the trick—and it'll even cure your case of the Mondays.



In 2013, rese........ Read more »

Stothard ER, McHill AW, Depner CM, Birks BR, Moehlman TM, Ritchie HK, Guzzetti JR, Chinoy ED, LeBourgeois MK, Axelsson J.... (2017) Circadian Entrainment to the Natural Light-Dark Cycle across Seasons and the Weekend. Current biology : CB, 27(4), 508-513. PMID: 28162893  

  • February 28, 2017
  • 10:43 AM
  • 171 views

Outcome in Early Education Interventions (Educare)

by William Yates, M.D. in Brain Posts

Despite centuries of experience in education, the best time to start formal education is still under debate. Is five years of age too old? Is three years of age too early?One issue with early education interventions is the potential for catch-up in children starting school later. In other words, early gains with younger children may evaporate overtime.One recent research study examines effectiveness of a child development intervention known as Educare. Educare seeks to reduce the achievement gap........ Read more »

Yazejian, N., Bryant, D., Hans, S., Horm, D., St. Clair, L., File, N., & Burchinal, M. (2017) Child and Parenting Outcomes After 1 Year of Educare. Child Development. DOI: 10.1111/cdev.12688  

  • February 28, 2017
  • 07:03 AM
  • 133 views

Quasi-periodic acceleration of electrons in the flare on 2012 July 19 by Jing Huang et al.*

by CESRA in Solar Radio Science

We study the quasi-periodic pulsations (QPPs) of nonthermal emission in an M7.7 class flare on 2012 July 19 with spatially resolved observations at microwave and HXR bands and with spectral observations at decimetric, metric waves. Microwave emission at 17 GHz of two footpoints, HXR emission at 20–50 keV of the north footpoint and loop top, and type III bursts at 0.7–3 GHz show prominent in-phase oscillations at 270$\,$s. Through the [...]... Read more »

Huang, J., Kontar, E., Nakariakov, V., & Gao, G. (2016) QUASI-PERIODIC ACCELERATION OF ELECTRONS IN THE FLARE ON 2012 JULY 19. The Astrophysical Journal, 831(2), 119. DOI: 10.3847/0004-637X/831/2/119  

  • February 28, 2017
  • 02:42 AM
  • 174 views

Premature mortality in intellectual disability in Australia (and England)

by Paul Whiteley in Questioning Answers

"Adults with ID [intellectual disability] experience premature mortality and over-representation of potentially avoidable deaths."The paper by Julian Trollor and colleagues [1] (open-access available here) provides some sombre reading today, as once again the topic of early mortality is raised on this blog. Looking at several measures - the "Age Standardised Mortality Rate (ASMR), Comparative Mortality Figure (CMF), years of productive life lost (YPLL) and proportion of deaths with pot........ Read more »

  • February 27, 2017
  • 05:29 AM
  • 183 views

Know your brain: Mammillary bodies

by neurosci in Neuroscientifically Challenged

Where are the mammillary bodies?























The mammillary bodies are part of the diencephalon, which is a collection of structures found between the brainstem and cerebrum. The diencephalon includes the hypothalamus, and the mammillary bodies are found on the inferior surface of the hypothalamus (the side of the hypothalamus that is closer to the brainstem). The mam........ Read more »

Vann SD, & Aggleton JP. (2004) The mammillary bodies: two memory systems in one?. Nature reviews. Neuroscience, 5(1), 35-44. PMID: 14708002  

  • February 27, 2017
  • 04:39 AM
  • 165 views

The First Family of Chaco

by teofilo in Gambler's House

A fascinating and important article about Chaco was published last week in Nature Communications, an open-access offshoot of the venerable journal Nature (already a good sign). Since it’s open-access, the full text of the article is available free online here. The researchers behind the article, based mainly at Penn State and Harvard but also including […]... Read more »

Kennett, D., Plog, S., George, R., Culleton, B., Watson, A., Skoglund, P., Rohland, N., Mallick, S., Stewardson, K., Kistler, L.... (2017) Archaeogenomic evidence reveals prehistoric matrilineal dynasty. Nature Communications, 14115. DOI: 10.1038/ncomms14115  

  • February 27, 2017
  • 03:16 AM
  • 185 views

Low muscle tone and autistic traits

by Paul Whiteley in Questioning Answers

"This large study showed a prospective association of infant muscle tone with autistic traits in childhood."So said the findings reported by Fadila Serdarevic and colleagues [1] who, looking at nearly 3000 children, were able to assess early motor development and muscle tone "between ages 2 and 5 months" and later parental ratings of autistic traits in children at 6 years of age. Said autistic traits were surveyed using the "the Social Responsiveness Scale (SRS) and the Pervasive Developmental P........ Read more »

Serdarevic F, Ghassabian A, van Batenburg-Eddes T, White T, Blanken LM, Jaddoe VW, Verhulst FC, & Tiemeier H. (2017) Infant muscle tone and childhood autistic traits: A longitudinal study in the general population. Autism research : official journal of the International Society for Autism Research. PMID: 28181411  

  • February 26, 2017
  • 06:53 PM
  • 177 views

Expert Knowledge: Birds and Worms

by Joshua Fisher in Text Savvy

As adults with expert knowledge, we see the logical and mathematical similarities between the “how many more” and “won’t get” situations, and, thus we are easily fooled into believing that applying skills and knowledge in one task is equivalent to doing so in the other.... Read more »

  • February 25, 2017
  • 04:07 AM
  • 224 views

1 in 5 children "met criteria for low language at 7 years"

by Paul Whiteley in Questioning Answers

Although primarily looking at the potential predictors of language outcome, the study results published by Cristina McKean and colleagues [1] revealed the rather important title heading this blog entry: "Almost 19% of children (22/1204;18.9%) met criteria for low language at 7 years."The source of the finding was a cohort of some 1900 infants "recruited at age 8 to 10 months" who were followed until aged 7 years old and subject to quite a bit of research inspection looking at "early life factors........ Read more »

McKean C, Reilly S, Bavin EL, Bretherton L, Cini E, Conway L, Cook F, Eadie P, Prior M, Wake M.... (2017) Language Outcomes at 7 Years: Early Predictors and Co-Occurring Difficulties. Pediatrics. PMID: 28179482  

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