Today I picked a special article on corporate risks. “How Risky is your Company?” by Robert Simons of the Harvard Business School. Its a more business oriented view on how companies should handle risks, internally. But since internal risk management can be seen as a part of supply chain risk management, I also include it here.... Read more »
Simons, R. (1999) How Risky is your Company?. Harvard Business Review, 85-94. info:/
In today’s population of just over 7 billion people, more than 900 million are undernourished and over 2 billion have nutrient deficiencies, yet over 1 billion adults are overweight. Lots of work has gone on to address the problems of undernourishment and obesity, but the problem of nutrient deficiency has taken second place.
... Read more »
Remans R, Flynn DF, DeClerck F, Diru W, Fanzo J, Gaynor K, Lambrecht I, Mudiope J, Mutuo PK, Nkhoma P.... (2011) Assessing nutritional diversity of cropping systems in African villages. PloS one, 6(6). PMID: 21698127
Cholera is a disease of seemingly endless fascination to epidemiologists for good reason. Vibrio cholerae emerged on a global stage in the 19th century just in time for the beginnings of modern medicine to grapple with it and for its transmission to prove the worth of epidemiological work. Although we understand its treatment and transmission [...]... Read more »
Another post inspired by Quora. Someone asked the question: "Can brain trauma cause cognitive enhancement?".Obviously this topic is dear to me, so I felt compelled to answer.(Read previously on my TEDx talk, my Neuron paper on functional recovery after stroke, my PNAS paper on working memory network deficits after stroke, why we don't need a brain, and my discussion of Rep. Grabrielle Giffords' brain surgery).The full response to the Quora question is below.*****Maybe! But most likely only in ve........ Read more »
Reverberi, C. (2005) Better without (lateral) frontal cortex? Insight problems solved by frontal patients. Brain, 128(12), 2882-2890. DOI: 10.1093/brain/awh577
The Zuker lab recently reported the existence of taste hotspots in gustatory cortex. I go through the paper, and look at what that means.... Read more »
Self-rating is a popular way to measure emotional intelligence in the workplace. Under lab conditions it's been shown that these ratings vary depending on what your (imaginary) objective is: to give a 'true' picture or to successfully win a job. A new study translates this lab finding to the workplace, finding that applicants for jobs really do rate themselves higher on EI than counterparts already working in that organisation.
The study compared scores for 109 job applicants with 239 volunteer........ Read more »
Lievens, F., Klehe, U., & Libbrecht, N. (2011) Applicant Versus Employee Scores on Self-Report Emotional Intelligence Measures. Journal of Personnel Psychology, 10(2), 89-95. DOI: 10.1027/1866-5888/a000036
I haven't done many walkalongs about new papers, so let's review a new paper from Charles Zuker's lab.
First, two pieces of background. There are two diametrically opposed theories of taste coding. The "labeled line" theory states that each taste quality (sweet, salty, bitter, etc.) is encoded by a single cell type, and individual cells respond to single taste qualities. In contrast,... Read more »
It’s really hot right now in Texas. We are in extreme drought. This weekend things became heated on my neighborhood email list when someone asked if our HOA had relaxed standards since so many lawns were brown. Multiple others took offense. Finally, someone recommended a cool glass of water for everyone. What’s amusing is that [...]
Related posts:When cross-examination [of the expert witness] offends
But, your honor! That witness was drunk!
The Jury Expert for May 2010 is uploaded
... Read more »
Baron, R., & Bell, P. (1976) Aggression and heat: The influence of ambient temperature, negative affect, and a cooling drink on physical aggression. Journal of Personality and Social Psychology, 33(3), 245-255. DOI: 10.1037//0022-35184.108.40.206
When you hear the word “angiogenesis,” do you start hissing? Many of us associate angiogenesis with tumors on their way to becoming malignant cancer. Well, if it weren’t for angiogenesis, we’d all be in trouble. Angiogenesis is the formation of blood vessels from pre-existing ones, and is a key process during development.
Blood vessels are the tubular structures that transport all of the good stuff in our blood. The formation of blood vessels depends on angiogenesis, the process in ........ Read more »
Zygmunt, T., Gay, C., Blondelle, J., Singh, M., Flaherty, K., Means, P., Herwig, L., Krudewig, A., Belting, H., Affolter, M.... (2011) Semaphorin-PlexinD1 Signaling Limits Angiogenic Potential via the VEGF Decoy Receptor sFlt1. Developmental Cell. DOI: 10.1016/j.devcel.2011.06.033
Buffer Because Facebook use can evoke a positive emotional state. Researchers have esthablished these positive responses during an expirement in which they measured several psychophysiological measures. They recorded skin conductance, blood volume pulse, electroencephalogram, electromyography, respiratory activity, and pupil dilationstate. They measured these psychophysiological patterns in 30 healthy subjects during relaxation condition, showing slides of [...]
No related posts.... Read more »
Mauri, M., Cipresso, P., Balgera, A., Villamira, M., & Riva, G. (2011) Why Is Facebook So Successful? Psychophysiological Measures Describe a Core Flow State While Using Facebook. Cyberpsychology, Behavior, and Social Networking, 2147483647. DOI: 10.1089/cyber.2010.0377
Oldest fossilized cells ever found seem to be sulphur metabolizing bacteria... Read more »
Wacey, D., Kilburn, M., Saunders, M., Cliff, J., & Brasier, M. (2011) Microfossils of sulphur-metabolizing cells in 3.4-billion-year-old rocks of Western Australia. Nature Geoscience. DOI: 10.1038/ngeo1238
It’s an age-old aphorism preached to us by our parents, teachers, and coaches – Don’t Judge a Book By Its Cover. The lesson has manifested itself in a number of ways throughout history: Shakespeare said that all that glitters is not gold; MLK told us to judge a person not by the color of their [...]... Read more »
Wansink, B., Payne, C., & North, J. (2007) Fine as North Dakota wine: Sensory expectations and the intake of companion foods. Physiology , 90(5), 712-716. DOI: 10.1016/j.physbeh.2006.12.010
Does HIV-1 Tat protein induce pain in HIV/AIDS sufferers? Notice a Tat induced increase in activity when compared to control or inactivated protein. (Taken from: Chi, et al, 2011)
Pain is an extremely complicated symptom - just see the TED talk below on chronic pain, yet of the 33.4 million people currently living with HIV/AIDS worldwide, 90% will experience peripheral neuropathy - otherwise known as pain. This a general unrecognised and under-diagnosed (and under-treated) outcome of HIV infe........ Read more »
Chi, X., Amet, T., Byrd, D., Chang, K., Shah, K., Hu, N., Grantham, A., Hu, S., Duan, J., Tao, F.... (2011) Direct Effects of HIV-1 Tat on Excitability and Survival of Primary Dorsal Root Ganglion Neurons: Possible Contribution to HIV-1-Associated Pain. PLoS ONE, 6(9). DOI: 10.1371/journal.pone.0024412
As Tropical Storm Lee makes landfall over the Louisiana coast and moves inland into southeast Louisiana, Mississippi, and Alabama, primary concerns include extensive flooding and damage from looming tornado weather. Tropical cyclones, or hurricanes, actually produce conditions amenable to tornado genesis.... Read more »
McCaul, E. W., Jr., D.E.Buechler, S.J.Goodman, and M.Cammarata. (2004) Doppler radar and lightning network observations of a severe outbreak of tropical cyclone tornadoes. Mon. Wea. Rev. info:/
It seems as though every couple of months a new paper is published reporting Yersinia pestis DNA from ancient remains. This week brought the latest installment from London’s East Smithfield Black Death cemetery. This cemetery holds a special place in the scientific investigations of the Black Death because it is so well documented as being [...]... Read more »
Schuenemann, V., Bos, K., DeWitte, S., Schmedes, S., Jamieson, J., Mittnik, A., Forrest, S., Coombes, B., Wood, J., Earn, D.... (2011) PNAS Plus: Targeted enrichment of ancient pathogens yielding the pPCP1 plasmid of Yersinia pestis from victims of the Black Death. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1105107108
A small "Signal-to-Noise Ratio" means that there is not enough real information (signal) compared to the background noise to make a definitive statement about something. With a sufficiently high Signal-to-Noise Ratio, it is possible to make statistically valid statements about some measure or observation. This applies to a lot of day to day decisions you make in life.
Climate change denialists understand this principle and they use it to try to fool people into thinking that "the jury is still........ Read more »
Santer, B., Karl, T., Lanzante, J., Meehl, G., Stott, P., Taylor, K., Thorne, P., Wehner, M., Wentz, F., Mears, C.... (2011) Separating Signal and Noise in Atmospheric Temperature Changes: The Importance of Timescale. Journal of Geophysical Research. DOI: 10.1029/2011JD016263
Ketoacidosis associated with fruitarianism.... Read more »
Causso C, Arrieta F, Hernández J, Botella-Carretero JI, Muro M, Puerta C, Balsa JA, Zamarron I, & Vázquez C. (2010) Severe ketoacidosis secondary to starvation in a frutarian patient. Nutricion hospitalaria : organo oficial de la Sociedad Espanola de Nutricion Parenteral y Enteral, 25(6), 1049-52. PMID: 21519781
How do you make a cloud? Well, first you start with an aerosol particle, a small particle around which the much larger cloud condensation nuclei (CCNs) can condense. It takes a large CCN – at least 100 nanometres in size – for water vapour to be able to condense from water vapour. Clouds are made [...]... Read more »
Kirkby, J., Curtius, J., Almeida, J., Dunne, E., Duplissy, J., Ehrhart, S., Franchin, A., Gagné, S., Ickes, L., Kürten, A.... (2011) Role of sulphuric acid, ammonia and galactic cosmic rays in atmospheric aerosol nucleation. Nature, 476(7361), 429-433. DOI: 10.1038/nature10343
A paper published this month by researchers from the University of Alberta (Canada) looked at a trade-off between proposed industrial developments and protecting habitats the industry would destroy.
How you choose which areas of land to preserve is a much-debated issue. In this paper they worked on the premise that by protecting every ecosystem type in the area most species will have their needs met.
... Read more »
Schneider, R., Hauer, G., Farr, D., Adamowicz, W., & Boutin, S. (2011) Achieving Conservation when Opportunity Costs Are High: Optimizing Reserve Design in Alberta's Oil Sands Region. PLoS ONE, 6(8). DOI: 10.1371/journal.pone.0023254
Intro/background: This is a post written as part of the Science Online London blogging workshop, which I am using to show how to embed media into a WordPress blog post and how to collaborate. The theme of the conference workshops is “spinal muscular atrophy”, and this post briefly explains how induced pluripotent stem cells can [...]... Read more »
Selvaraj, V., Plane, J., Williams, A., & Deng, W. (2010) Switching cell fate: the remarkable rise of induced pluripotent stem cells and lineage reprogramming technologies. Trends in Biotechnology, 28(4), 214-223. DOI: 10.1016/j.tibtech.2010.01.002
Ebert, A., Yu, J., Rose, F., Mattis, V., Lorson, C., Thomson, J., & Svendsen, C. (2008) Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature, 457(7227), 277-280. DOI: 10.1038/nature07677
Makhortova, N., Hayhurst, M., Cerqueira, A., Sinor-Anderson, A., Zhao, W., Heiser, P., Arvanites, A., Davidow, L., Waldon, Z., Steen, J.... (2011) A screen for regulators of survival of motor neuron protein levels. Nature Chemical Biology, 7(8), 544-552. DOI: 10.1038/nchembio.595
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