A Friday Weird Science guest post on Neurotic Physiology takes a humorous look at anogenital distance and its implication for fertility in adult males.... Read more »
Eisenberg, M., Hsieh, M., Walters, R., Krasnow, R., & Lipshultz, L. (2011) The Relationship between Anogenital Distance, Fatherhood, and Fertility in Adult Men. PLoS ONE, 6(5). DOI: 10.1371/journal.pone.0018973
A popular series argues that positive thoughts attract positive events. What does psychology research have to say?... Read more »
Murray, S., Holmes, J., & Griffin, D. (1996) The benefits of positive illusions: Idealization and the construction of satisfaction in close relationships. Journal of Personality and Social Psychology, 70(1), 79-98. DOI: 10.1037/0022-3518.104.22.168
Recapping a cool study that locates where the receptors underlying the arousing effects of caffeine live in the brain....... Read more »
Lazarus M, Shen HY, Cherasse Y, Qu WM, Huang ZL, Bass CE, Winsky-Sommerer R, Semba K, Fredholm BB, Boison D.... (2011) Arousal Effect of Caffeine Depends on Adenosine A2A Receptors in the Shell of the Nucleus Accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(27), 10067-10075. PMID: 21734299
Great news for conservation is always exciting, so when I read about a remarkable wildlife rebound in this month's issue of PLoS ONE, I couldn't resist sharing it here. ... Read more »
Aburto-Oropeza, O., Erisman, B., Galland, G., Mascareñas-Osorio, I., Sala, E., . (2011) Large recovery of fish biomass in a no-take marine reserve. PLoS ONE. DOI: 10.1371/journal.pone.0023601
Sergio, F., Newton, I., Marchesi, L., , & Pedrini, P. (2006) Ecologically justified charisma: Preservation of top predators delivers biodiversity conservation. Journal of Applied Ecology, 1049-1055. DOI: 10.1111/j.1365-2664.2006.01218.x
A look at the biggest drugs news stories of the year and a statistical analysis of drugs deaths this year.... Read more »
Nutt, D., King, L., & Phillips, L. (2010) Drug harms in the UK: a multicriteria decision analysis. The Lancet, 376(9752), 1558-1565. DOI: 10.1016/S0140-6736(10)61462-6
Measham,F. Moore, K. Østergaard, J. (2011) Mephedrone, ‘‘Bubble’’ and unidentiﬁed white powders: the contested identities of synthetic ‘‘legal highs". DRUGS AND ALCOHOL TODAY, 137-146. info:/
Editorial team. (2010) The EMCDDA annual report 2010: the state of the drugs problem in Europe. The European Monitoring Centre for Drugs and Drug Addiction, also published in Euro surveillance :European communicable disease bulletin, 15(46). PMID: 21144426
This year 134 suspect new journals have appeared from the abyss, all published by the same clandestine company “Scientific & Academic Publishing, USA“... Read more »
Morrison, Heather. (2012) Scholarly Communication in Crisis. Freedom for scholarship in the internet age. Simon Fraser University School of Communication. info:/
What happens in an empirical test of the idea of magnetism-driven star formation, as compared to turbulence-driven star formation?... Read more »
Ohm's law (current proportional to voltage) was first formulated in 1827 and the discoverer George Ohm would be pleased to know that in 2012 the law still holds even at the smallest possible nanoscale. Weber et al. in their report in Science do not explain how they would expect conductors to behave in another way at this nanoscale but ventured ahead anyway to create a truly tiny electrical wire, run a current through it and measure resistivity. ... Read more »
Over in the US it has apparently become so difficult to get hold of pseudoephedrine (Sudafed), that one researcher has published a satirical paper explaining how to manufacture it out of crystal meth (PDF). The paper describes how “in the past most stores were able to sell pseudoephedrine”, the US’s most popular decongestant but new laws require only pharmacies, often with restricted opening hours to sell the medicine only to those carrying government issued ID. The paper argue........ Read more »
Hai, O. Hakkenshit, I.B. (2012) A Simple and Convenient Synthesis of Pseudoephedrine From N-Methylamphetamine. Journal of Apocryphal Chemistry. info:/
Rover-based research and the results of 3D simulations of the Martian ice table depth, as well as the formation of pure ice lenses.... Read more »
Sizemore, H., Mellon, M., Searls, M., Lemmon, M., Zent, A., Heet, T., Arvidson, R., Blaney, D., & Keller, H. (2010) In situ analysis of ice table depth variations in the vicinity of small rocks at the Phoenix landing site. Journal of Geophysical Research. DOI: 10.1029/2009JE003414
Sizemore, H. G., Zent, A. P., & Rempel, A. W. (2012) Ice Lens Formation and Unfrozen Water at the Phoenix Landing Site. 43rd Lunar and Planetary Science Conference. DOI: 2012LPI..43.2397S
A team of researchers from the Harvard School of Public Health in Boston have studied more than 120,000 people over 30 years to find that ‘red meat consumption is associated with an increased risk of total, CVD [Cardiovascular disease], and cancer mortality.’... Read more »
Pan, A., Sun, Q., Bernstein, A., Schulze, M., Manson, J., Stampfer, M., Willett, W., & Hu, F. (2012) Red Meat Consumption and Mortality: Results From 2 Prospective Cohort Studies. Archives of Internal Medicine. DOI: 10.1001/archinternmed.2011.2287
Five years from now it may be possible to prevent breast cancer by taking a simple blood test. New research shows that the chances of developing the disease are linked to a molecular modification of the gene ATM, present on white blood cells. In the future, doctors may identify women with this molecular modification to prevent breast cancer occurrence.... Read more »
Brennan, K., Garcia-Closas, M., Orr, N., Fletcher, O., Jones, M., Ashworth, A., Swerdlow, A., Thorne, H., , ., Riboli, E.... (2012) Intragenic ATM Methylation in Peripheral Blood DNA as a Biomarker of Breast Cancer Risk. Cancer Research, 72(9), 2304-2313. DOI: 10.1158/0008-5472.CAN-11-3157
The Smith Cloud, a high-velocity neutral hydrogen cloud in the halo of the Milky Way, helps explain how the Galaxy has been able to continue forming stars at its current rate, despite an apparent lack of interstellar gas.... Read more »
Lockman, F., Benjamin, R., Heroux, A., & Langston, G. (2008) The Smith Cloud: A High-Velocity Cloud Colliding with the Milky Way. The Astrophysical Journal, 679(1). DOI: 10.1086/588838
Lockman, F. (2012) The Milky Way and its gas: Cold fountains and accretion. EPJ Web of Conferences, 8003. DOI: 10.1051/epjconf/20121908003
The man on the picture, William McElligott, spent 28 years of his life driving a delivery truck in Chicago. Only the left side of his face was exposed to the sun, with the result that it now looks much older than his right side. His case is a rare reminder of the aging effects of the sun, but also of the need to take precautions when working under certain conditions.... Read more »
We recently published a gene expression microarray-based paper in PLOS Neglected Tropical Diseases. As a "reductionist", it was challenging for me to deal with the massive amount of data associated with the paper. ... Read more »
Ray D, Nelson TA, Fu CL, Patel S, Gong DN, Odegaard JI, & Hsieh MH. (2012) Transcriptional profiling of the bladder in urogenital schistosomiasis reveals pathways of inflammatory fibrosis and urothelial compromise. PLoS neglected tropical diseases, 6(11). PMID: 23209855
Recent surprising evidence has shown that metastatic tumors usually do not vary in their genomes within an individual. Yet, these tumors behave differently at different sites around the body. Does that mean that epigenetic profiling will be too variable to target for cancer treatment? In a word, no.... Read more »
Aryee MJ, Liu W, Engelmann JC, Nuhn P, Gurel M, Haffner MC, Esopi D, Irizarry RA, Getzenberg RH, Nelson WG.... (2013) DNA methylation alterations exhibit intraindividual stability and interindividual heterogeneity in prostate cancer metastases. Science translational medicine, 5(169). PMID: 23345608
That is the recipe for depression. Chronic Mild Stress (CMS). Or at least it is the recipe I used to depress rats. As I mentioned earlier I worked with rats to research the mood-effects of Salvia. One important piece of this research was the idea that a depressed brain is different than a healthy brain and may respond differently to drug exposure. So in order to apply that in rats, I needed a way to create depressed rats. For me, that meant using CMS.
... Read more »
Katz, R. (1982) Animal model of depression: Pharmacological sensitivity of a hedonic deficit. Pharmacology Biochemistry and Behavior, 16(6), 965-968. DOI: 10.1016/0091-3057(82)90053-3
Willner, P. (2005) Chronic Mild Stress (CMS) Revisited: Consistency and Behavioural-Neurobiological Concordance in the Effects of CMS. Neuropsychobiology, 52(2), 90-110. DOI: 10.1159/000087097
For the first time, researchers have found that stress can leave an epigenetic mark on sperm, which then alters the offspring’s hypothalamic-pituitary-adrenal (HPA) axis, a part of the brain that deals with responding to stress. The study was published in the Journal of Neuroscience.... Read more »
Rodgers, A., Morgan, C., Bronson, S., Revello, S., & Bale, T. (2013) Paternal Stress Exposure Alters Sperm MicroRNA Content and Reprograms Offspring HPA Stress Axis Regulation. Journal of Neuroscience, 33(21), 9003-9012. DOI: 10.1523/JNEUROSCI.0914-13.2013
Ten years ago, Professor Miguel Nicolelis and his team at Duke University made history. They implanted electrodes — sensors — into a monkey’s brain and trained her to control a robotic arm with her thoughts. That may sound like the stuff of science-fiction, but his latest work is even more incredible. In a paper recently published in Scientific Reports, Professor Nicolelis and his team used similar technology to enable a pair of rats to communicate — one brain to another ........ Read more »
Pais-Vieira, M., Lebedev, M., Kunicki, C., Wang, J., . (2013) A Brain-to-Brain Interface for Real-Time Sharing of Sensorimotor Information. Scientific Reports. DOI: 10.1038/srep01319
s it how much you’re expected to eat? How much you should eat? Pardon me, but if I want to eat an entire bag of potato chips, that’s exactly what I’m going to do.
I say this as the guy who helps create nutrition facts panels for food products for a living. I have read, reread, proof read, and colored red hundreds of these little tables in my time, and believe it or not, people aren’t lining up at parties to hear my thrilling stories... Read more »
Conrad J. Choinière, & Amy Lando. (2008) 2008 Health and Diet Survey. FDA Consumer Behavior Research Foos Safety Surveys (FSS). info:/
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