Post List

Research / Scholarship posts

(Modify Search »)

  • August 12, 2014
  • 02:07 PM
  • 288 views

Treatment and Prevention of PTSD

by Dr. Jekyll in Lunatic Laboratories

It’s no secret for anyone who follows me that I am a Marine veteran. It’s also no secret for anyone who follows me that I’ve had my own ups and downs in life because of my experiences. PTSD is a nightmare, one that you can’t quite shake no matter how hard you try. Then again, not everyone reacts the same way to the trauma that typically causes PTSD, not everyone walks away from war with it. The big question that scientists set out to answer was, why? And now they might just have an answer.[…]... Read more »

Nikolaos P. Daskalakis, Hagit Cohen, Guiqing Caia, Joseph D. Buxbaum, & Rachel Yehuda. (2014) Expression profiling associates blood and brain glucocorticoid receptor signaling with trauma-related individual differences in both sexes. Proceedings of the National Academy of Sciences of the United States of America, 111(32). info:/10.1073/pnas.1401660111

  • August 11, 2014
  • 01:30 PM
  • 348 views

New Hope for Autoimmune Diseases

by Dr. Jekyll in Lunatic Laboratories

Autoimmune diseases are on the rise. Since I have a history of over sharing, my Uncle suffered from a form of lupus. It caused him intense and — in my opinion — unbearable pain although he shouldered it like the incredible man he was and never complained. My sister unfortunately is suffering from a rare disease that has yet to be diagnosed, which in my opinion has autoimmune dysfunction as the root cause. If you or anyone you know suffers in a similar fashion then you know that the treatments for such things are, expensive, moderately effective at best, and are overall inadequate.[…]... Read more »

Chhabra S, Chang SC, Nguyen HM, Huq R, Tanner MR, Londono LM, Estrada R, Dhawan V, Chauhan S, Upadhyay SK.... (2014) Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. PMID: 24891519  

  • August 10, 2014
  • 12:03 PM
  • 324 views

Pregnancy and Antibacterial Soap a Potentially Dangerous Combination

by Dr. Jekyll in Lunatic Laboratories

My wife likes to sanitize everything with bleach. I don’t really approve, but I bite my tongue because it makes her feel better. Germs are everywhere and honestly there is […]... Read more »

Pycke BF, Geer LA, Dalloul M, Abulafia O, Jenck AM, & Halden RU. (2014) Human biomonitoring of prenatal exposure to triclosan and triclocarban in a multiethnic urban population from Brooklyn, New York. Environmental Science , 8831-8838. info:/10.1021/es501100w

  • August 10, 2014
  • 05:18 AM
  • 337 views

Canine Science Forum 2014 - we come full circle!

by Cobb & Hecht in Do You Believe In Dog?

Aw - it's Us @ CSF2014! Thanks Tamás Faragó :)Dear Julie,while you've been off enjoying the fjords of Norway and I've been recovering from six legs of long haul flying with a three year old as hand luggage, I thought I'd put up a quick post to recap the wonderful week in Lincoln, UK that was the (Feline and) Canine Science Forum 2014.Such a fun, stimulating, inspiring week comprising the Feline Science day (Monday), public lecture by James Serpell (rhymes with purple) on Monday evening, Canine Science Forum (Tue-Wed-Thu), including the wonderful gala dinner at Lincoln Castle on Wednesday night and finally, the Companion Animals: Human Health & Disease day (Friday).If anyone out there happened to miss it, we live tweeted nearly all of the presentations so you can easily catch up on all the great thoughts via the magic of Storify here. Feline Science Day:[View the story "Feline Science Forum 2014" on Storify]Public lecture by James Serpell:[View the story "Feline & Canine Science Forum, Public Lecture: James Serpell" on Storify] Canine Science Forum Day 1:[View the story "4th Canine Science Forum - Lincoln UK 2014 - Day 1" on Storify] Canine Science Forum Day 2:[View the story "4th Canine Science Forum - Lincoln UK 2014 - Day 2" on Storify]Which, of course, included us being real life #scientists (we don't make this stuff up!): You talked about Project: Play with Your Dog and the role that citizen science can play in canine science.Nancy Dreschel (now on Twitter at @ndreschel) presented the key findings from our collaborative meta-analysis looking at canine salivary cortisol.And I explored if using group averages is really the best way to determine and analyse the stress and welfare experience of working dogs (and my points were relevant to all animals!). Then we drank wine in at a castle. Which was a mighty fine way to end that day. Canine Science Forum Day 3:[View the story "4th Canine Science Forum - Lincoln UK 2014 - Day 3" on Storify]Companion  Animals: Human Health & Disease 2014... Read more »

  • August 9, 2014
  • 01:45 PM
  • 602 views

Marijuana and the Developing Brain

by Dr. Jekyll in Lunatic Laboratories

You can’t get away from it, the big marijuana debate here in the US. Is it good? Is it bad? What are other countries doing? There are also a lot of claims made about marijuana, most of which aren’t true, namely the big medical claims. Then there is the other side of that fence, what about some of the health issues that are claimed, where does science sit on that?[…]... Read more »

Giedd JN, Blumenthal J, Jeffries NO, Rajapakse JC, Vaituzis AC, Liu H, Berry YC, Tobin M, Nelson J, & Castellanos FX. (1999) Development of the human corpus callosum during childhood and adolescence: a longitudinal MRI study. Progress in neuro-psychopharmacology , 23(4), 571-88. PMID: 10390717  

Giedd, J. N. (2004) Structural magnetic resonance imaging of the adolescent brain. Adolescent Brain Development: Vulnerabilities and Opportunities. info:/

Choo EK, Benz M, Zaller N, Warren O, Rising KL, & McConnell KJ. (2014) The impact of state medical marijuana legislation on adolescent marijuana use. The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 55(2), 160-6. PMID: 24742758  

Joffe A, American Academy of Pediatrics Committee on Substance Abuse, & American Academy of Pediatrics Committee on Adolescence. (2004) Legalization of marijuana: potential impact on youth. Pediatrics, 113(6), 1825-6. PMID: 15173518  

  • August 8, 2014
  • 03:36 PM
  • 328 views

The Self Assembling Brain

by Dr. Jekyll in Lunatic Laboratories

Let’s face it, if the brain were a lego set I would still be staring at the box wondering what I got myself into. So I guess we can just […]... Read more »

Lorenzo I. Finci et. al. (2014) The Crystal Structure of Netrin-1 in Complex with DCC Reveals the Bifunctionality of Netrin-1 As a Guidance Cue. Neuron. info:/http://dx.doi.org/10.1016/j.neuron.2014.07.010

  • August 8, 2014
  • 09:13 AM
  • 249 views

Translational Findings: How fruit fly research has already contributed to human health

by Bethany Christmann in Fly on the Wall

How have fruit flies already contributed to human health? I review four landmark fly papers that won their authors Nobel Prizes in Physiology or Medicine. ... Read more »

  • August 7, 2014
  • 02:11 PM
  • 394 views

Nerve Regeneration: Another Piece of the Stem Cell Puzzle

by Dr. Jekyll in Lunatic Laboratories

Almost everyone regenerates nerves, but you! Sure, yesterday we talked about how other animals in the kingdom regenerate damaged nerves and how we got left in the dust. But we […]... Read more »

  • August 6, 2014
  • 07:14 PM
  • 360 views

Wait before you stamp out your next cigarette! Scientists use cigarette filters in advanced energy storage materials

by Jonathan Trinastic in Goodnight Earth

Scientists in Seoul use cigarette filters as electrode materials in supercapacitors based on a simple pyrolytic carbonization process.... Read more »

  • August 6, 2014
  • 01:29 PM
  • 458 views

Nerve Regeneration: Everyone does it, but you

by Dr. Jekyll in Lunatic Laboratories

Dogs do it, frogs do it, and even whales do it! No this isn’t everyone poops. I’m talking about regrowing nerves after an injury and sadly, we don’t do it… yet. […]... Read more »

  • August 5, 2014
  • 01:28 PM
  • 277 views

Weight loss Stalled? Kick those Hunger Cravings!

by Dr. Jekyll in Lunatic Laboratories

Trying to drop the weight, but find yourself picking up more of it? Is your diet failing because you are so hungry you could eat a horse?  Well a new […]... Read more »

Li SS, Kendall CW, de Souza RJ, Jayalath VH, Cozma AI, Ha V, Mirrahimi A, Chiavaroli L, Augustin LS, Blanco Mejia S.... (2014) Dietary pulses, satiety and food intake: A systematic review and meta-analysis of acute feeding trials. Obesity (Silver Spring, Md.), 22(8), 1773-80. PMID: 24820437  

  • August 4, 2014
  • 03:00 PM
  • 242 views

One Gene, One Cancer

by Viputheshwar Sitaraman in Draw Science

A mutation in the BRAF gene, called V599E, is purportedly the cause of several different cell pathways leading to the symptoms of melanoma. This mutation is present in many patients with melanoma, and stopping it could mean a cure or treatment. [Infographic]... Read more »

Hingorani SR, Jacobetz MA, Robertson GP, Herlyn M, & Tuveson DA. (2003) Suppression of BRAF(V599E) in human melanoma abrogates transformation. Cancer research, 63(17), 5198-202. PMID: 14500344  

  • August 4, 2014
  • 02:02 PM
  • 289 views

Want a Larger Brain: How About an Implant?

by Dr. Jekyll in Lunatic Laboratories

Feel like you could use some extra grey matter? Maybe get a dash of genius added to all those cobwebs in the brain? Well then science might just have the […]... Read more »

Hemmer, K., Zhang, M., van Wüllen, T., Sakalem, M., Tapia, N., Baumuratov, A., Kaltschmidt, C., Kaltschmidt, B., Schöler, H., Zhang, W.... (2014) Induced Neural Stem Cells Achieve Long-Term Survival and Functional Integration in the Adult Mouse Brain. Stem Cell Reports. DOI: 10.1016/j.stemcr.2014.06.017  

  • August 3, 2014
  • 04:11 PM
  • 370 views

The Alondra Oubré Academic Fraud Exposed

by nooffensebut in The Unsilenced Science

Two respected authors, Alondra Oubré and Massimo Pigliucci, are implicated in the academic fraud of taking false information from Wikipedia and falsely attributing it to a research database in order to fulminate against the conclusions of Nicholas Wade’s book, A Troublesome Inheritance, and the science of the warrior gene, monoamine oxidase A.... Read more »

Alia-Klein N, Goldstein RZ, Tomasi D, Woicik PA, Moeller SJ, Williams B, Craig IW, Telang F, Biegon A, Wang GJ.... (2009) Neural mechanisms of anger regulation as a function of genetic risk for violence. Emotion (Washington, D.C.), 9(3), 385-96. PMID: 19485616  

Buckholtz JW, Callicott JH, Kolachana B, Hariri AR, Goldberg TE, Genderson M, Egan MF, Mattay VS, Weinberger DR, & Meyer-Lindenberg A. (2008) Genetic variation in MAOA modulates ventromedial prefrontal circuitry mediating individual differences in human personality. Molecular psychiatry, 13(3), 313-24. PMID: 17519928  

Cerasa A, Cherubini A, Quattrone A, Gioia MC, Magariello A, Muglia M, Manna I, Assogna F, Caltagirone C, & Spalletta G. (2010) Morphological correlates of MAO A VNTR polymorphism: new evidence from cortical thickness measurement. Behavioural brain research, 211(1), 118-24. PMID: 20303364  

Fergusson DM, Boden JM, Horwood LJ, Miller A, & Kennedy MA. (2012) Moderating role of the MAOA genotype in antisocial behaviour. The British journal of psychiatry : the journal of mental science, 200(2), 116-23. PMID: 22297589  

Gilad Y, Rosenberg S, Przeworski M, Lancet D, & Skorecki K. (2002) Evidence for positive selection and population structure at the human MAO-A gene. Proceedings of the National Academy of Sciences of the United States of America, 99(2), 862-7. PMID: 11805333  

Huang YY, Cate SP, Battistuzzi C, Oquendo MA, Brent D, & Mann JJ. (2004) An association between a functional polymorphism in the monoamine oxidase a gene promoter, impulsive traits and early abuse experiences. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 29(8), 1498-505. PMID: 15150530  

Koen L, Kinnear C, Corfield V, Emsley R, Jordaan E, Keyter N, Moolman-Smook J, Stein D, & Niehaus D. (2004) Violence in male patients with schizophrenia: risk markers in a South African population. Australian and New Zealand Journal of Psychiatry, 38(4), 254-259. DOI: 10.1111/j.1440-1614.2004.01338.x  

Kunugi H, Ishida S, Kato T, Tatsumi M, Sakai T, Hattori M, Hirose T, & Nanko S. (1999) A functional polymorphism in the promoter region of monoamine oxidase-A gene and mood disorders. Molecular psychiatry, 4(4), 393-5. PMID: 10483059  

Lei H, Zhang X, Di X, Rao H, Ming Q, Zhang J, Guo X, Jiang Y, Gao Y, Yi J.... (2014) A Functional Polymorphism of the MAOA Gene Modulates Spontaneous Brain Activity in Pons. BioMed research international, 243280. PMID: 24971323  

Philibert RA, Gunter TD, Beach SR, Brody GH, & Madan A. (2008) MAOA methylation is associated with nicotine and alcohol dependence in women. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 147B(5), 565-70. PMID: 18454435  

Williams RB, Marchuk DA, Gadde KM, Barefoot JC, Grichnik K, Helms MJ, Kuhn CM, Lewis JG, Schanberg SM, Stafford-Smith M.... (2003) Serotonin-related gene polymorphisms and central nervous system serotonin function. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 28(3), 533-41. PMID: 12629534  

Wong CC, Caspi A, Williams B, Craig IW, Houts R, Ambler A, Moffitt TE, & Mill J. (2010) A longitudinal study of epigenetic variation in twins. Epigenetics : official journal of the DNA Methylation Society, 5(6), 516-26. PMID: 20505345  

Yu YW, Tsai SJ, Hong CJ, Chen TJ, Chen MC, & Yang CW. (2005) Association study of a monoamine oxidase a gene promoter polymorphism with major depressive disorder and antidepressant response. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 30(9), 1719-23. PMID: 15956990  

  • August 3, 2014
  • 02:37 PM
  • 316 views

Is Fat making you… Fat?

by Dr. Jekyll in Lunatic Laboratories

Fast food, let’s face it, it’s not the best for you. Yet Mcdonalds and Pizza hut are known practically world wide [although menu options differ]. With the rise of our […]... Read more »

  • August 3, 2014
  • 11:34 AM
  • 346 views

Ignoring the dangers: fracking development outpacing knowledge of biotic impact

by Jonathan Trinastic in Goodnight Earth

New collaborative research across several institutions indicate a complete lack of knowledge about how fracking spills, accidents, and water contamination affect nearby biospheres.... Read more »

Souther, S., Tingley, M., Popescu, V., Hayman, D., Ryan, M., Graves, T., Hartl, B., & Terrell, K. (2014) Biotic impacts of energy development from shale: research priorities and knowledge gaps. Frontiers in Ecology and the Environment, 12(6), 330-338. DOI: 10.1890/130324  

  • August 2, 2014
  • 04:51 PM
  • 496 views

Parental Age and the Rise of Autism Spectrum Disorder

by Alexis Delanoir in How to Paint Your Panda

It has been documented that there has been a rise in Autism Spectrum Disorder (ASD) in the United States, and that a large cause of this is due to redefinition of the disorder in the Diagnostic and Statistical Manual of Mental Disorders - Fifth Edition (DSM-V) and an increased familiarization among psychiatrists and psychologists; but there is an unexplained portion of the increase. Studies have shown that parental age, namely maternal age can confer a higher risk for ASD. With the rise of parental age in the United States, does this association explain the undocumented portion of ASD increase? This post examines the data provided by the Center for Disease Control (CDC) and related studies to answer that question.... Read more »

  • August 2, 2014
  • 01:53 PM
  • 322 views

At risk for Cancer? Try Spicy Food!

by Dr. Jekyll in Lunatic Laboratories

Like spicy food? Well next time you eat some you should hug that chili pepper, because he might just save your life. This is an interesting find, researchers have found that […]... Read more »

de Jong PR, Takahashi N, Harris AR, Lee J, Bertin S, Jeffries J, Jung M, Duong J, Triano AI, Lee J.... (2014) Ion channel TRPV1-dependent activation of PTP1B suppresses EGFR-associated intestinal tumorigenesis. The Journal of clinical investigation. PMID: 25083990  

  • August 1, 2014
  • 01:12 PM
  • 312 views

Possible treatment and Prevention for Parkinson’s

by Dr. Jekyll in Lunatic Laboratories

Parkinson’s disease affects neurons in a particular brain region, when it develops brain cells have their mitochondrial activity cease and then the cells die. But now researchers have shown that supplying D-lactate […]... Read more »

  • July 31, 2014
  • 01:33 PM
  • 301 views

Mitochondria and Anti Aging

by Dr. Jekyll in Lunatic Laboratories

I’m sure you can all relate, you go to fix the sink and in the process you build a new kitchen on accident. Anyone… no? Well that is sort of […]... Read more »

join us!

Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.

If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.

Register Now

Research Blogging is powered by SMG Technology.

To learn more, visit seedmediagroup.com.