Cancer, one of the oldest and most formidable foes of humanity has an advanced, new adversary. 16 terminally-ill liver cancer patients treated with a high dose of the vaccine Pexa-Vec survived an average of 14.1 months, compared to 6.7 for patients receiving a low dose.... Read more »
Heo J, Reid T, Ruo L, Breitbach, C., Rose S, Bloomston M, Cho M, Lim H, Chung H, Kim, C.... (2013) Randomized Dose-Finding Clinical Trial of Oncolytic Immunotherapeutic Vaccinia JX-594 in Liver Cancer. Nature Medicine. DOI: 10.1038/nm.3089
Courtney killed Kurt. Cancer has a cure. Aliens built the pyramids. 9/11 was an inside job. Territory once regarded as the domain of your hare-brained uncle, eccentric neighbor, or other vaguely threatening social leper, seems lately to have leaked precariously into the mainstream. The idea that elaborate conspiracies are being worked upon the nation –nay, the world – seem to be accepted more and more as not just true, but worthy of vitriolic defense by anyone who might call into qu........ Read more »
Marathe, A., Lewis, B., Barrett, C., Chen, J., Marathe, M., Eubank, S., & Ma, Y. (2011) Comparing Effectiveness of Top-Down and Bottom-Up Strategies in Containing Influenza. PLoS ONE, 6(9). DOI: 10.1371/journal.pone.0025149
Grapefruits, albeit sour, are nutritious and can be delicious. But they’ve also been known to interfere with many medications, and even some dietary supplements. So, many doctors try to steer some patients away from eating grapefruit.... Read more »
Greenblatt, D., Zhao, Y., Hanley, M., Chen, C., Harmatz, J., Cancalon, P., & Gmitter, F. (2012) Mechanism-based inhibition of human Cytochrome P450-3A activity by grapefruit hybrids having low furanocoumarin content. Xenobiotica, 42(12), 1163-1169. DOI: 10.3109/00498254.2012.700428
What do you do when you’re single and want to have sex? There’s the option to hookup with strangers. But you can also stay in your “comfort zone” and have sex with someone you already hang out with.... Read more »
Lehmiller, J., VanderDrift, L., & Kelly, J. (2012) Sexual Communication, Satisfaction, and Condom Use Behavior in Friends with Benefits and Romantic Partners. Journal of Sex Research, 1-12. DOI: 10.1080/00224499.2012.719167
If you are reading things from home or from the office, chances are there is something from Ikea in the room. Over the past decade, the affordable and semi-clever designs from the Swedish furniture juggernaut have become one of those recognizable symbols regardless of where in the world you live. And one aspect that is true about most Ikea stuff, is that you probably built it yourself. And if you built it yourself, there is a certain satisfaction that comes with having used that strange little........ Read more »
If the quest for the perfect night’s sleep remains one of your goals, you might need to start at the grocery store.
A recently published study out of the University of Pennsylvania isolated a few key nutrients and total caloric intake as contributing factors for length and duration of sleep. They also looked at the role that overall diet, demographics, socioeconomics, physical activity, and obesity, to rule out other potential causes.... Read more »
Grandner M, Jackson N, Gerstner J, & Knutson K. (2013) Dietary nutrients associated with short and long sleep duration. Data from a nationally representative sample. Appetite. DOI: 10.1016/j.appet.2013.01.004
North Americans and Europeans have ballooned up to noticeably fatter proportions in recent decades, and new research originating from the University of Granada has revealed a direct connection between exposure to pesticides in food, air, and water & incidence of adult-onset type 2 diabetes. The relationship was found to exist without respect to age, gender or body mass index, according to data in the study.... Read more »
Arrebola, J., Pumarega, J., Gasull, M., Fernandez, M., Martin-Olmedo, P., Molina-Molina, J., Fernández-Rodríguez, M., Porta, M., & Olea, N. (2013) Adipose tissue concentrations of persistent organic pollutants and prevalence of type 2 diabetes in adults from Southern Spain. Environmental Research. DOI: 10.1016/j.envres.2012.12.001
It’s important to find a balance in life between work and relaxation. In order to put your mind and body at ease, you may like to take a hot bath, roll out a yoga mat or enjoy a massage. But according to science there are more ways that lead to calmness. ... Read more »
Barker, R., Knisely, J., Barker, S., Cobb, R., & Schubert, C. (2012) Preliminary investigation of employee's dog presence on stress and organizational perceptions. International Journal of Workplace Health Management, 5(1), 15-30. DOI: 10.1108/17538351211215366
Lee, J., Lee, J., Lim, H., Son, J., Lee, J., Kim, D., & Ko, S. (2012) Cartoon Distraction Alleviates Anxiety in Children During Induction of Anesthesia. Anesthesia , 115(5), 1168-1173. DOI: 10.1213/ANE.0b013e31824fb469
Martin, F., Rezzi, S., Peré-Trepat, E., Kamlage, B., Collino, S., Leibold, E., Kastler, J., Rein, D., Fay, L., & Kochhar, S. (2009) Metabolic Effects of Dark Chocolate Consumption on Energy, Gut Microbiota, and Stress-Related Metabolism in Free-Living Subjects. Journal of Proteome Research, 8(12), 5568-5579. DOI: 10.1021/pr900607v
Historical accounts tell us that the stimulating power of caffeine was first noticed in the 9th century by an Ethiopian goatherd who found his flock wildly excited after consuming coffee berries. Whoever he was, a substantial portion from the efforts of human progress since remains indebted to that discovery.... Read more »
Shown at three times natural speed, this video the first ever thought being documented while it was being formed. The zebrafish is an ideal candidate for this advanced area of study as its skin remains transparent during early development. The brilliant flash in this particular moment coincided with the passing of a nearby paramecium, and correlated with hunting behavior in the zebrafish. To put it bluntly, the fish was thinking; dinner. Truly a remarkable leap forward in field of neuroscience... Read more »
Muto, A., Ohkura, M., Abe, G., Nakai, J., & Kawakami, K. (2013) Real-Time Visualization of Neuronal Activity during Perception. Current Biology. DOI: 10.1016/j.cub.2012.12.040
The skulls have very different forms, they lay in a seemingly insignificant location, and some of them have fingers in their eyes. What happened here?... Read more »
Morehart, C., Peñaloza, A., Sánchez, C., de Tapia, E., & Morales, E. (2012) Human Sacrifice During the Epiclassic Period in the Northern Basin of Mexico. Latin American Antiquity, 23(4), 426-448. DOI: 10.7183/1045-66126.96.36.1996
In the book ‘The Science of Yoga,’ William J. Broad discusses more than a century of research on the risks and rewards of yoga, confirming what we may already know about the ancient practice, but also revealing its dirty little secrets.... Read more »
Balasubramaniam M, Telles S, & Doraiswamy PM. (2012) Yoga on our minds: a systematic review of yoga for neuropsychiatric disorders. Frontiers in psychiatry / Frontiers Research Foundation, 117. PMID: 23355825
Hi Julie!What a busy week I’ve found myself having! Very productive indeed, with a lot of this:and some more of that: Fuelled by a ton of this:But I did take time to notice that your cat Josh broke something new. Oh Josh! Thanks for telling me about your ISHAR presentation about dogs and cats in the home. I can definitely relate to the importance of early socialisation = best chance at harmony. Take my dog Elke, for example.As a pup, she met and spent time aroun........ Read more »
Mellor David J., & Bayvel Angus Campbell David. (2008) New Zealand's inclusive science-based system for setting animal welfare standards. Applied Animal Behaviour Science, 113(4), 313-329. DOI: 10.1016/j.applanim.2008.01.010
Mellor DJ. (2012) Animal emotions, behaviour and the promotion of positive welfare states. New Zealand Veterinary Journal, 60(1), 1-8. DOI: 10.1080/00480169.2011.619047
Feeling like you’re falling behind on sleep lately? Don’t worry too much. Recently published research from the University of Sydney demonstrated that sleep duration shifts periodically over the course of the month. These shifts occur independent of lifestyle, social, and/or environmental influences.
‘Sleep requirements vary in a cyclical fashion and between individuals. If you incur a sleep debt, your body will signal a need to catch up on extra sleep,’ said Dr. Chi........ Read more »
Wong, S., Halaki, ., & Chow, . (2013) The periodicity of sleep duration – an infradian rhythm in spontaneous living. Nature and Science of Sleep, 1. DOI: 10.2147/NSS.S38116
There is quite a bit of debate about the scientific validity of the proverb “money can’t buy happiness”, because studies on this topic have resulted in discordant results. Some studies support the idea that richer people are happier on average than poor people, but there are also reports that while the median income in the US has grown in recent decades, average happiness among Americans has hardly changed.... Read more »
De Neve, J., & Oswald, A. (2012) Estimating the influence of life satisfaction and positive affect on later income using sibling fixed effects. Proceedings of the National Academy of Sciences, 109(49), 19953-19958. DOI: 10.1073/pnas.1211437109
Since 2007 when terahertz pulsed imaging (TPI) was first developed to non-destructively measure the coating thickness of pharmaceutical tablets there has been intense research in the PSSRC into how this technique can help improve the quality of pharmaceutical coatings and thus make controlled release technology based on coatings of single dosage forms attractive to industry.... Read more »
Zeitler, J., Shen, Y., Baker, C., Taday, P., Pepper, M., & Rades, T. (2007) Analysis of coating structures and interfaces in solid oral dosage forms by three dimensional terahertz pulsed imaging. Journal of Pharmaceutical Sciences, 96(2), 330-340. DOI: 10.1002/jps.20789
Brock, D., Zeitler, J., Funke, A., Knop, K., & Kleinebudde, P. (2012) A comparison of quality control methods for active coating processes. International Journal of Pharmaceutics, 439(1-2), 289-295. DOI: 10.1016/j.ijpharm.2012.09.021
Sex, it turns out, is a risky affair. Besides infidelity, sexually transmitted diseases or pregnancy, it can also perpetuate harmful genes. Also, compared to asexual reproduction, it’s very inefficient—bacteria, strawberries and even some amphibians don’t have to look for a mate. So, why have sex—sexual reproduction, that is?... Read more »
Otto, S. (2008) Sexual reproduction and the evolution of sex. Nature Education, 1(1). info:/
As you read this very post, you may be sitting at home, one of the small but growing percentage of individuals around the world who work from home. Or perhaps you some work from home and other days you go to the office. Whatever the arrangement, is it a well known trend with a mix of benefits and long term questions, as more businesses and workers invest in the concept of what is sometimes called telework. Frequently updated research looks into aspects such as cost/benefit and productivity. ........ Read more »
Are you one of the millions around the world that work from home full time? Are you satisfied with your work-life balance? New research from the UK compares the level of satisfaction between those working from home, those working at the office, and those in between.... Read more »
In last week's issue of Science, Melissa Gymrek and colleagues from the lab of Yaniv Erlich (Whitehead) report a method for the triangulation the identity of a sample donor using genomic data and public databases.
As a proof-of-principle, they uncovered the identities of about 50 sample donors from the CEPH Utah collection, perhaps the best-studied collection of "anonymous" samples to date. Their approach exploits several facts of this "information age" we live in.... Read more »
Gymrek M, McGuire AL, Golan D, Halperin E, & Erlich Y. (2013) Identifying personal genomes by surname inference. Science (New York, N.Y.), 339(6117), 321-4. PMID: 23329047
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