Research shows microRNA based strategy to fight against viral pathogens.... Read more »
Langlois, RA, Albrecht, RA, Kimble, B, Sutton, T, Shapiro, JS, Finch, C, Angel, M, Chua, MA, Gonzalez-Reiche, AS, Xu, K.... (2013) MicroRNA-based strategy to mitigate the risk of gain-of-function influenza studies. . Nature Biotechnology. DOI: 10.1038/nbt.2666
“I’ve heard stories that some modeling agents encourage girls to do speed and cocaine in order to speed up metabolism and eat less,” Russian model Kira Dikhtyar told Fox News.
It’s an alarming phenomenon that many models and socialites use cocaine to stay thin. And this is not just a lady thing. Nowadays, prevailing beauty standards also influence men in a way some opt to use the same method to lose weight.... Read more »
Ersche, KD, Stochl, J, Woodward, JM, & Fletcher, PC. (2013) The skinny on cocaine. Insights into eating behavior and body weight in cocaine-dependent men. Appetite. DOI: 10.1016/j.appet.2013.07.011
Hydrogen is one of the most promising alternative fuels being investigated. Not only because burning it only produces water but because it can act as a sort of chemical storage for more intermittent sources of energy. While there are many ways to chemically produce hydrogen gas, most involve expensive metals like platinum as a catalyst to make the process at all economical. Another approach borrows from biology, and in particular the enzyme hydrogenase. As with many things borrowed from nature it’s extremely good at what it does, the issue is extracting the enzyme from a living organism for use on its own. Fortunately some researchers from Germany (Ruhr-Universität Bochum) have managed to do the next best thing.... Read more »
Esselborn J, Lambertz C, Adamska-Venkatesh A, Simmons T, Berggren G, Noth J, Siebel J, Hemschemeier A, Artero V, Reijerse E.... (2013) Spontaneous activation of [FeFe]-hydrogenases by an inorganic [2Fe] active site mimic. Nature chemical biology. PMID: 23934246
The point of surgical procedures is to save or improve the quality of our lives, but things can and do go wrong because of system or human errors. In too many cases patients are failed because of so called “never events” – serious incidents that should never happen because they’re entirely preventable.
The official list of never events in surgery includes operating on the wrong part of the body, performing the wrong procedure, leaving instruments or swabs inside the body, or having the wrong prosthesis or medical device implanted.
Never events, such as having the wrong testicle removed, can be devastating, while others prove fatal.... Read more »
Blaming Facebook is a popular train of thought, also for scientists. They already conducted many studies on the, mostly negative, psychological effects of the social network. Here are 8 findings, some of them contradictive.... Read more »
Fenne große Deters, & Matthias R. Mehl. (2013) Does Posting Facebook Status Updates Increase or Decrease Loneliness? An Online Social Networking Experiment. Social Psychological and Personality Science . DOI: 10.1177/1948550612469233
Stephanie Tom Tong. (2012) Facebook Use During Relationship Termination: Uncertainty Reduction and Surveillance. Cyberpsychology, Behavior, and Social Networking. DOI: 10.1089/cyber.2012.0549
Tara C. Marshall. (2012) Facebook Surveillance of Former Romantic Partners: Associations with PostBreakup Recovery and Personal Growth. Cyberpsychology, Behavior, and Social Networking. DOI: 10.1089/cyber.2012.0125
Clayton RB, Nagurney A, & Smith JR. (2013) Cheating, Breakup, and Divorce: Is Facebook Use to Blame?. Cyberpsychology, behavior and social networking. PMID: 23745615
Chen W, & Lee KH. (2013) Sharing, Liking, Commenting, and Distressed? The Pathway Between Facebook Interaction and Psychological Distress. Cyberpsychology, behavior and social networking. PMID: 23745614
Gonzales AL, & Hancock JT. (2011) Mirror, mirror on my Facebook wall: effects of exposure to Facebook on self-esteem. Cyberpsychology, behavior and social networking, 14(1-2), 79-83. PMID: 21329447
Chou HT, & Edge N. (2012) "They are happier and having better lives than I am": the impact of using Facebook on perceptions of others' lives. Cyberpsychology, behavior and social networking, 15(2), 117-21. PMID: 22165917
Objective quantification of taste intensity would be extremely useful for product development and quality control in the food industry. The tastes of industrial food products in development are still usually discriminated by trained food panelists that sense and score the tastes of foods by tasting the products themselves. Therefore there is a limit number of products that can be evaluated in a single sitting, and this limitation poses a crucial disadvantage in the case of quality control in an industrial production area.... Read more »
Misaka, T. (2013) Development of a Cultured Cell-Based Human-Taste Evaluation System. Biosci. Biotechnol. Biochem., 77(8). DOI: 10.1271/bbb.130288
Yarmolinsky, DA, Zuker, CS, & Ryba, NJP. (2009) Common sense about taste: from mammals to insects. Cell. DOI: 10.1016/j.cell.2009.10.001
Hi Mia & Julie – Firstly, thanks so much for letting me drop a verse in the rap song of your blog! I feel so awesome being featured. It’s like being Lil Wayne or something. Anyway…I’m just recently back from ISAZ 2013, where I had a most excellent time chatting with other anthrozoologist-y types. As you know, I just graduated from the Anthrozoology Master’s Program at Canisius College, so I was uber-excited to have a chance to share my research with colleagues in the field. ISAZ did not disappoint. Pauleen Bennett & Heather at ISAZ 2013Now I get to share with you two and it just gets better and better! :-)My master’s thesis research project (advised by the oh-so-awesome Christy Hoffman) looked to answer the question: “Does Black Dog Syndrome Exist?”Animal welfare folks are probably familiar with the concept of Black Dog Syndrome (BDS) that Julie introduced last week: it’s the idea that dogs with black coats have a harder time than other dogs getting adopted, and as a result, may face higher rates of euthanasia and longer stays in adoption programs. Popular media - but is it correct?A lot of popular media articles focus on this concept (like here, here, here and here) but the research results have been mixed: in a study published earlier this year, participants rated an image of a black dog as significantly less agreeable, less conscientious, and less emotionally stable than a yellow dog (Fratkin & Baker, 2013). Yet research into factors influencing shelter dogs’ lengths of stay (LOS) found that LOS was not significantly correlated with coat color (Brown, Davidson, & Zuefle, 2013; Protopopova, Gilmour, Weiss, Shen, & Wynne, 2012).To dig deeper into the questions of whether potential adopters discriminate against black dogs in a shelter and whether black dog discrimination is reflected in shelter stats, I conducted a two-part research project: Shelter Visitor Pilot Study – examined interaction between potential adopters and shelter dogs Shelter Data Analysis Study – investigated relationships between LOS and coat color, age, sex and breed, as well as the impact of these variables on likelihood of euthanasiaAnd what I found may surprise you. There was very little evidence to support the concept of Black Dog Syndrome! From Heather's ISAZ 2013 posterI know animal shelter workers are going “WHAT!?” right now – I know because I AM a shelter worker – but the truth is, even if many potential adopters come to the shelter with a negative bias toward black dogs, it’s not resulting in crazy-long shelter stays or greater risk of euthanasia for black dogs. In fact, according to analysis of shelter statistics, black dogs were adopted out faster than average at both shelters in my study. Black dogs were also less likely than expected to be euthanized (good news for black dogs, eh?).When shelter visitors video-recorded their walk through the adoption area, I found that they spent about equal amounts of time looking at every dog, regardless of coat color. Visitors also rarely made specific comments with regards to coat color, although one guy did say: “I like black. Black dogs ... Read more »
Fratkin Jamie L., & Baker Suzanne C. (2013) The Role of Coat Color and Ear Shape on the Perception of Personality in Dogs. Anthrozoos: A Multidisciplinary Journal of The Interactions of People , 26(1), 125-133. DOI: 10.2752/175303713X13534238631632
Protopopova Alexandra, Gilmour Amanda Joy, Weiss Rebecca Hannah, Shen Jacqueline Yontsye, & Wynne Clive David Lawrence. (2012) The effects of social training and other factors on adoption success of shelter dogs. Applied Animal Behaviour Science, 142(1-2), 61-68. DOI: 10.1016/j.applanim.2012.09.009
Autism reveals itself in different ways in women than in men, according to new research from the University of Cambridge. And this has the potential to great advance our understanding of the condition.
Autism is estimated to affect 1% of the population and is believed to be more prevalent in males. As most studies have focused on this gender, this has led to a male-biased understanding of autism and, the Cambridge researchers say, the prevalence of female autism could be largely underestimated.... Read more »
Meng-Chuan Lai, Michael V. Lombardo, John Suckling, Amber N. V. Ruigrok, Bhismadev Chakrabarti, Christine Ecker, Sean C. L. Deoni, Michael C. Craig, Declan G. M. Murphy, Edward T. Bullmore, MRC AIMS Consortium, Simon Baron-Cohen. (2013) Biological sex affects the neurobiology of autism. Brain. DOI: 10.1093/brain/awt216
In humans, recent theories have suggested that contagious yawning is an indicator of empathy. When we yawn in response to someone else’s yawn, we are communicating that we empathise with them. Being the social creatures that we are, empathy is an important social emotion that can strengthen the bonds between people.
But what about when a dog yawns after seeing a human yawn? Is the dog being empathic, or is there some other explanation?... Read more »
Romero T, Konno A . (2013) Familiarity bias and physiological responses in contagious yawning by dogs support link to empathy. PLoS ONE. DOI: 10.1371/journal.pone.0071365
What do bankers and bacteria have in common? Finite resources, quick decision-making and an appreciation of trade-offs, according to a study in Ecology Letters. So could bacterial modelling ever help us avoid another banking crash?... Read more »
Ram Maharjan1,Susanna Nilsson, Judy Sung, Ken Haynes, Robert E. Beardmore, Laurence D. Hurst, Tom Ferenci, Ivana Gudelj. (2013) The form of a trade-off determines the response to competition. Ecology Letters. DOI: 10.1111/ele.12159
Practically everyone knows friends or family suffering from heart disease. Many sufferers have ischaemic heart disease, the most common type of heart disease worldwide. The World Health Organisation ranked ischaemic heart disease as the leading cause of death in 2004...... Read more »
Berenson GS, Srinivasan SR, Bao W, Newman WP 3rd, Tracy RE, & Wattigney WA. (1998) Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. The Bogalusa Heart Study. The New England journal of medicine, 338(23), 1650-6. PMID: 9614255
Chen LJ, Lim SH, Yeh YT, Lien SC, & Chiu JJ. (2012) Roles of microRNAs in atherosclerosis and restenosis. Journal of biomedical science, 19(1), 79. PMID: 22931291
Lee RC, Feinbaum RL, & Ambros V. (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell, 75(5), 843-54. PMID: 8252621
Raitoharju E, Lyytikäinen LP, Levula M, Oksala N, Mennander A, Tarkka M, Klopp N, Illig T, Kähönen M, Karhunen PJ.... (2011) miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study. Atherosclerosis, 219(1), 211-7. PMID: 21820659
Climate change resulting from increased atmospheric carbon dioxide (CO2) and other greenhouse gases could also have other consequences.
Scientists are concerned that the absorption of atmospheric CO2 in the oceans could have an impact on marine ecosystems. This would result from absorption of atmospheric CO2, which causes a decrease in seawater pH and carbonate ion concentrations, while increasing CO2 and bicarbonate ion concentrations.... Read more »
Kroeker KJ, Gambi MC and Micheli F. (2013) Community dynamics and ecosystem simplification in a high-CO2 ocean. Proceedings of the National Academy of Sciences of the United States of America. DOI: 10.1073/pnas.1216464110
Professor Paul Piff at UC Berkeley recently conducted a study attempting to see if there was some type of correlation between a person’s socio-economic status and the way they conduct themselves morally and ethically. Piff felt compelled to disprove the popular conservative stereotype that people in lower socio-economic positions tend to act out of greed and personal benefit.... Read more »
Piff PK, Stancato DM, Côté S, Mendoza-Denton R, & Keltner D. (2012) Higher social class predicts increased unethical behavior. Proceedings of the National Academy of Sciences of the United States of America, 109(11), 4086-91. PMID: 22371585
All scientific evidence points to the fact that, if you go far enough back, all life on Earth is related through common ancestry. Turns out that applying the same sort of analysis shows that all humans alive today are descendants of one man and one woman who walked our planet thousands of years ago.
For several decades, there has been debate about when these ancestors, popularly known as Y-chromosomal Adam and mitochondrial Eve, existed. Two studies published this week find that there is a good chance Adam and Eve may have existed about the same time, evolutionarily speaking.... Read more »
Could you ever imagine that one day testing a protein in your tiny sample would be so easy, just like performing a pregnancy strip test at home. Yes, this is made possible by a group of chemists from Johannes Gutenberg University Mainz (JGU). They have developed a new method for multiple protein analysis that is, in principle, capable of identifying hundreds or even thousands of different proteins.... Read more »
Rosman C, Prasad J, Neiser A, Henkel A, Edgar J, & Sönnichsen C. (2013) Multiplexed Plasmon Sensor for Rapid Label-Free Analyte Detection. Nano letters. PMID: 23789876
I recently came across a very interesting paper by Y. Yu and X. Meng who present an interweaving strategy between different model parameterizations to improve mixing. It is well known that different model parameterizations can perform better than others under certain conditions. Papaspiliopoulos, Roberts and Sköld  present a general framework for how to parameterize […]The post Model Scale Parameterization for MCMC Efficiency appeared first on Lindons Log.... Read more »
Yu Yaming, & Meng Xiao-Li. (2011) To Center or Not to Center: That Is Not the Question—An Ancillarity–Sufficiency Interweaving Strategy (ASIS) for Boosting MCMC Efficiency. Journal of Computational and Graphical Statistics, 20(3), 531-570. DOI: 10.1198/jcgs.2011.203main
In China the lightest material on Earth has recently been invented. Its weight makes it so light that it can be sustained by a blade of grass or a stalk of a flower. It’s an aerogel that has the form of a paper sheet and has the width of a carbon atom. Thanks to its characteristic shape, the material can take on many forms and dimensions. Also, it has the remarkable capability of absorbing liquid substances up to 900 times its weight.... Read more »
Sun H, Xu Z, & Gao C. (2013) Multifunctional, ultra-flyweight, synergistically assembled carbon aerogels. Advanced materials (Deerfield Beach, Fla.), 25(18), 2554-60. PMID: 23418099
In Lewis Caroll’s Through the Looking Glass, Alice wanders into a garden with flowers that can talk — the “garden of Live Flowers”. Of course, all plants are alive, but here the flowers are called “live” because they can talk. One of the greatest examples of human arrogance might be our attitude towards plants. We treat plants as objects, as part of the background, as mere things without any agency. We tend to forget that they’re dynamic, complex living creatures that react and respond to their environment — just in unfamiliar ways and on a different timescale.... Read more »
Sugimoto K, & Arimura GI. (2013) Maize plants prime anti-herbivore responses by the memorizing and recalling of airborne information in their genome. Plant signaling , 8(10). PMID: 23887489
While people cheating on their partners is frowned upon in modern society, monogamy among mammals is something of an evolutionary puzzle. Some stick to one sexual partner for a lifetime. That is why the evolution of monogamy among mammals is hotly debated. Two studies published this week, including one I worked on, weigh in on the debate.
Evolution dictates that genes have the final say. And if there is one thing genes want, it is to spread as far and wide as possible. That is why monogamy is rare among mammals.
Females have to wait for a long gestation period to have a child, where as males could go and inseminate many other females in that time. Most male mammals behave in this manner, but some don’t, and are monogamous.... Read more »
Christopher Opiea, Quentin D. Atkinson, Robin I. M. Dunbarc, and Susanne Shultzd. (2013) Male infanticide leads to social monogamy in primates. Proceedings of the National Academy of Sciences of the United States of America PNAS, Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1307903110
Genetics is becoming a bigger and bigger part of modern medicine as our knowledge increases. From diagnostics, to research, and even potential treatments, advanced biotechnologies are becoming more common.
Each of these medical fields requires precise analysis and often manipulation of human DNA. Diagnostics may require mutating certain genes to see what the effect is, in the hopes of identifying disease risk. For research and drug testing scientists need to have cell cultures that mimic the genetic characteristics of various diseases. And for many conditions with a genetic component, gene therapy is being researched as a potential cure. The issue was that scientists didn’t have a standard tool for manipulating DNA in this way, until now.... Read more »
Pablo Perez-Pinera et al. (2013) RNA-guided gene activation by CRISPR-Cas9–based transcription factors. NATURE METHODS. DOI: 10.1038/nmeth.2600
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