Hormones and Research for Women’s Health. Hormones are powerful molecules. They are chemical messengers. And they exert powerful effects in many different ways. Changes in hormones effect athletic ability. TheyThe post Hormones: Exercise changes estrogens and reduces risk of breast cancer appeared first on WODMasters Stiff Competition.... Read more »
Smith AJ, Phipps WR, Thomas W, Schmitz KH, & Kurzer MS. (2013) The effects of aerobic exercise on estrogen metabolism in healthy premenopausal women. Cancer epidemiology, biomarkers , 22(5), 756-64. PMID: 23652373
Prefrontal Cortex Highlighted in RedIdentifying valid biomarkers for psychosis and schizophrenia is an active focus in brain research.Tyronne Cannon, Ph.D. from Yale University recently presented a summary of research on this topic at the William K. Warren Neuroscience Symposium in Tulsa, Oklahoma. Here are my notes from his presentation along with related free full-text research references.Biomarker research in psychosis is important because current treatment for psychosis with the antipsy........ Read more »
Sun D, van Erp TG, Thompson PM, Bearden CE, Daley M, Kushan L, Hardt ME, Nuechterlein KH, Toga AW, & Cannon TD. (2009) Elucidating a magnetic resonance imaging-based neuroanatomic biomarker for psychosis: classification analysis using probabilistic brain atlas and machine learning algorithms. Biological psychiatry, 66(11), 1055-60. PMID: 19729150
Seidman LJ, Giuliano AJ, Meyer EC, Addington J, Cadenhead KS, Cannon TD, McGlashan TH, Perkins DO, Tsuang MT, Walker EF.... (2010) Neuropsychology of the prodrome to psychosis in the NAPLS consortium: relationship to family history and conversion to psychosis. Archives of general psychiatry, 67(6), 578-88. PMID: 20530007
Gee DG, Karlsgodt KH, van Erp TG, Bearden CE, Lieberman MD, Belger A, Perkins DO, Olvet DM, Cornblatt BA, Constable T.... (2012) Altered age-related trajectories of amygdala-prefrontal circuitry in adolescents at clinical high risk for psychosis: a preliminary study. Schizophrenia research, 134(1), 1-9. PMID: 22056201
When you were young(er), did you also engage in personality predictions with your peers based on order in the family? For example, that the oldest of three siblings would be the bossiest and the youngest the most spoiled? Almost everyone (90% of us) have one or more siblings. And we know they play an important role in our lives. Scientists have now combined international research examining siblings’ role in children’s mental health. ... Read more »
Buist KL, Deković M, & Prinzie P. (2013) Sibling relationship quality and psychopathology of children and adolescents: a meta-analysis. Clinical psychology review, 33(1), 97-106. PMID: 23159327
The ability to gauge radiation at vanishingly low concentrations gives scientists a powerful tool for understanding ocean processes. “We can measure down to less than 1 becquerel”—one radioactive decay event per second, said Ken Buesseler, a marine chemist at Woods Hole Oceanographic Institution. “But just because we can measure it doesn’t mean it’s necessarily harmful to human health.”... Read more »
David Pacchioli. (2013) Radiation Health Risks. WHOI Oceanus Magazine. info:/
In spite of the evidence to the contrary and a lack of rationality in the claim, we continue to be told that increasing the number of people with a title, such as paramedic, will result in better care.
Here is more evidence that dividing the skills among more people leads to less skilled care.
The authors begin by referring to other studies that demonstrate the high failure rate of doctors performing procedures on children.
How is that relevant to EMS? We have a low frequency of use of ........ Read more »
Mittiga, M., Geis, G., Kerrey, B., & Rinderknecht, A. (2013) The Spectrum and Frequency of Critical Procedures Performed in a Pediatric Emergency Department: Implications of a Provider-Level View. Annals of Emergency Medicine, 61(3), 263-270. DOI: 10.1016/j.annemergmed.2012.06.021
Blaivas M. (2010) Inadequate needle thoracostomy rate in the prehospital setting for presumed pneumothorax: an ultrasound study. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 29(9), 1285-9. PMID: 20733183
Tanz RR, & Charrow J. (1993) Black clouds. Work load, sleep, and resident reputation. American journal of diseases of children (1960), 147(5), 579-84. PMID: 8488808
Meyr, A., Gonzalez, O., & Mayer, A. (2011) Quantification and Perception of On-call Podiatric Surgical Resident Workload. The Journal of Foot and Ankle Surgery, 50(5), 535-536. DOI: 10.1053/j.jfas.2011.04.035
When you think of drum circles taking place in the United States, visions of hippies, Birkenstocks and the vibrant green lawns of private colleges may appear. The bacteria Bacillus anthracis, or anthrax, does not often materialize alongside the skunky mix of patchouli and ganja hovering above the crowd in one’s visions of (ar)rhythmic drumming events.
... Read more »
Centers for Disease Control and Prevention (CDC). (2010) Gastrointestinal anthrax after an animal-hide drumming event - New Hampshire and Massachusetts, 2009. MMWR. Morbidity and mortality weekly report, 59(28), 872-7. PMID: 20651643
Radioactive iodine is dangerous, and public health and academic researchers are now trying to determine what long-term damage can occur, where it can occur, and how long it will take to occur. What politcs can learn from Fukushima.... Read more »
J. Mangano, J. (2013) Elevated airborne beta levels in Pacific/West Coast US States and trends in hypothyroidism among newborns after the Fukushima nuclear meltdown. Open Journal of Pediatrics, 03(01), 1-9. DOI: 10.4236/ojped.2013.31001
It is 6 am. In the soft morning light, we can barely see the monkeys. They have just exited their sleep tree and fed on some succulent Pourouma nearby. Their … Continue reading →... Read more »
Diaz James H. (2009) Recognition, Management, and Prevention of Hymenopteran Stings and Allergic Reactions in Travelers. Journal of Travel Medicine, 16(5), 357-364. DOI: 10.1111/j.1708-8305.2009.00316.x
Haddad Junior Vidal, Cardoso João Luiz Costa, & Moraes Roberto Henrique Pinto. (2005) Description of an injury in a human caused by a false tocandira (Dinoponera gigantea, Perty, 1833) with a revision on folkloric, pharmacological and clinical aspects of the giant ants of the genera Paraponera and Dinoponera (sub-family Ponerinae). Revista do Instituto de Medicina Tropical de São Paulo, 47(4), 235-238. DOI: 10.1590/S0036-46652005000400012
Szolajska Ewa, Poznanski Jaroslaw, Ferber Miguel López, Michalik Joanna, Gout Evelyne, Fender Pascal, Bailly Isabelle, Dublet Bernard, & Chroboczek Jadwiga. (2004) Poneratoxin, a neurotoxin from ant venom: structure and expression in insect cells and construction of a bio-insecticide. European Journal of Biochemistry, 271(11), 2127-2136. DOI: 10.1111/j.1432-1033.2004.04128.x
Johnson Stephen R., Copello Julio A., Evans M. Steven, & Suarez Andrew V. (2010) A biochemical characterization of the major peptides from the venom of the giant Neotropical hunting ant Dinoponera australis. Toxicon, 55(4), 702-710. DOI: 10.1016/j.toxicon.2009.10.021
Like Mother, like baby! Photo from freedigitalphotos.net.Moms give us so much more than we ever give them credit for. Biologically speaking, we all have a mom and a dad (unless you’re a flatworm or some other species that can reproduce without sex) that provide us with one of each chromosome type (our chromosomes contain our genes, commonly thought of as our “biological blueprints”). So it makes sense that we tend to think of ourselves as being half-our-mom and half-our-dad. But not so! Al........ Read more »
epression together with pain, but not pain alone, may increase activity in the immune system and inflammation. These are the important findings of a new study just published in the journal “Pain Medicine”.... Read more »
Kim Kristiansen, M.D. (2013) Pain and Depression Linked to the Immune System. Picture of Pain Blog. info:/
Shocker alert: medicines might have more effects than those listed on the patient information leaflet.I like being surprised. I particularly like being surprised about medicines and health, and how many of the medicines which even reside in the typical household medicines cabinet* might carry the potential to do so much more than that listed on the package insert. Leaking? @ Wikipedia Take for example the recent paper I bumped into by Sommansson and colleagues** continuing their ........ Read more »
Sommansson A, Wan Saudi WS, Nylander O, & Sjöblom M. (2013) Melatonin inhibits alcohol-induced increases in duodenal mucosal permeability in rats in vivo. American journal of physiology. Gastrointestinal and liver physiology. PMID: 23639810
A recently published paper in Scientific Reports has found that climate variability in the form of the North Atlantic Oscillation (NAO) has had a significant impact on the occurrence of disease outbreaks in Europe over the past fifty years. Researchers in France and the United Kingdom studied 2,058 outbreaks occurring in 36 countries from 114 infectious diseases from 1950 to 2009 and found that climatic variations and seasonal changes in air pressure across the continent attributed to the NAO in........ Read more »
Morand S, Owers KA, Waret-Szkuta A, McIntyre KM, & Baylis M. (2013) Climate variability and outbreaks of infectious diseases in Europe. Scientific reports, 1774. PMID: 23639950
If Valium makes you groggy, and Ambien makes you sleepwalk…
A compound that blocks a brain receptor you probably have never heard of may hold the key to the next generation of sleeping pills—and there is always a next generation of sleeping pills.
A new class of hypnotic compounds that serve as antagonists for the neurotransmitter orexin may combat insomnia without the “confusional arousals” that have come to plague some users of zolpidem, otherwise known as Ambien. Sleepwalking, s........ Read more »
Uslaner J. M., Tye S. J., Eddins D. M., Wang X., Fox S. V., Savitz A. T., Binns J., Cannon C. E., Garson S. L., & Yao L. (2013) Orexin Receptor Antagonists Differ from Standard Sleep Drugs by Promoting Sleep at Doses That Do Not Disrupt Cognition. Science Translational Medicine, 5(179), 179-179. DOI: 10.1126/scitranslmed.3005213
A particularly sinister aspect of drug addiction is relapse. To the ex-addict, environmental cues, life stressors and even the drug itself serve as the sirens’ call, beckoning them back into the deadly realm of abuse. Currently, doctors battle heroin temptations with psychotherapy and replacement opioid drugs, such as methadone. While effective, these treatments rely heavily [...]... Read more »
Schlosburg, J., Vendruscolo, L., Bremer, P., Lockner, J., Wade, C., Nunes, A., Stowe, G., Edwards, S., Janda, K., & Koob, G. (2013) Dynamic vaccine blocks relapse to compulsive intake of heroin. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1219159110
Sleep problems may increase your risk of prostate cancer, according to a new study. Get better sleep now with these simple tips.... Read more »
Sigurdardottir, L., Valdimarsdottir, U., Mucci, L., Fall, K., Rider, J., Schernhammer, E., Czeisler, C., Launer, L., Harris, T., Stampfer, M.... (2013) Sleep Disruption Among Older Men and Risk of Prostate Cancer. Cancer Epidemiology Biomarkers , 22(5), 872-879. DOI: 10.1158/1055-9965.EPI-12-1227-T
Coconut oil is being promoted by some as a “perfect” food. This is common in the CrossFit and Paleo communities. Coconut oil is like animal fat in that it isThe post Coconut oil and the search for the perfect diet. appeared first on WODMasters Stiff Competition.... Read more »
Enos RT, Davis JM, Velázquez KT, McClellan JL, Day SD, Carnevale KA, & Murphy EA. (2013) Influence of dietary saturated fat content on adiposity, macrophage behavior, inflammation, and metabolism: composition matters. Journal of lipid research, 54(1), 152-63. PMID: 23103474
When you bring up the subject of listening to music while stoned, you get a range of responses, almost all of them positive. While you might enjoy a song in a non-altered state, under the influence of Cannabis, it has been established that listening to and creating music is somehow a deeper and more intense experience. The disputed issue that arises is why this happens and if the feeling is real.... Read more »
As consumers, we like to hear that produce growers and distributers go above and beyond food safety mandates to ensure that healthy fresh fruits and vegetables do not carry bacteria or viruses that can make us sick. But in California’s Salinas Valley, some more vigorous interventions are cutting into the last corners of wildlife habitat, without evidence of food safety benefits, creating tensions between wildlife preservation and food safety where none need exist.... Read more »
Sasha Gennet, Jeanette Howard, Jeff Langholz, Kathryn Andrews, Mark D Reynolds, & Scott A Morrison. (2013) Farm practices for food safety: an emerging threat to floodplain and riparian ecosystems. Frontiers in Ecology and the Environment, e-View ahead of print(May 6th). info:/10.1890/1202443
A lot has changed in the human body since our ancestors walked around on bare feet. We have less hair, we got bigger and we live longer, for example. But we’re still being haunted by some very stubborn diseases that survived the evolution. How is that possible?... Read more »
You’ve been hearing it for years; don’t eat too much sugar, because sugar rots your teeth. It turns out that sugar isn’t the real culprit behind tooth decay. Researchers, looking at the bacteria responsible for dental cavities, had found a molecule that can stop these common dental problems.
Jose Cordova, a Yale University researcher, and Erich Astudillo, from the University of Chile, identified the new molecule, called Keep32, that kills the Streptococcus Mutans bacteria an........ Read more »
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